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| NCT ID | NCT03937219 |
| Title | Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (COSMIC-313) |
| Acronym | COSMIC-313 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Exelixis |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | POL | NZL | NLD | ITA | ISR | HUN | GBR | FRA | FIN | ESP | DEU | CZE | CAN | BRA | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Exelixis Clincal Site #129 | Ramat Gan | 5265601 | Israel | Details | ||
| Exelixis Clinical Site #1 | Spokane | Washington | 99208 | United States | Details | |
| Exelixis Clinical Site #10 | Nashville | Tennessee | 37203 | United States | Details | |
| Exelixis Clinical Site #100 | Santiago | 8420383 | Chile | Details | ||
| Exelixis Clinical Site #101 | Charlotte | North Carolina | 28204 | United States | Details | |
| Exelixis Clinical Site #102 | Charleston | South Carolina | 29425 | United States | Details | |
| Exelixis Clinical Site #104 | Perugia | 06132 | Italy | Details | ||
| Exelixis Clinical Site #105 | Winnipeg | Manitoba | R3E 0V9 | Canada | Details | |
| Exelixis Clinical Site #107 | Portland | Oregon | 97239 | United States | Details | |
| Exelixis Clinical Site #109 | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Exelixis Clinical Site #11 | North Adelaide | South Australia | 5006 | Australia | Details | |
| Exelixis Clinical Site #110 | Ciudad Autonoma de Buenos Aire | C1426ANZ | Argentina | Details | ||
| Exelixis Clinical Site #111 | Tuen Mun | Hong Kong | Details | |||
| Exelixis Clinical Site #112 | Brussels | 1000 | Belgium | Details | ||
| Exelixis Clinical Site #113 | Montréal | Quebec | H3T 1E2 | Canada | Details | |
| Exelixis Clinical Site #114 | Praha 4 | 140 59 | Czechia | Details | ||
| Exelixis Clinical Site #115 | Tübingen | Baden-Württemberg | 72076 | Germany | Details | |
| Exelixis Clinical Site #116 | La Jolla | California | 92093 | United States | Details | |
| Exelixis Clinical Site #117 | Frankfurt am main | Hessen | 60596 | Germany | Details | |
| Exelixis Clinical Site #118 | Praha 5 | 150 06 | Czechia | Details | ||
| Exelixis Clinical Site #119 | São Paulo | 01323-001 | Brazil | Details | ||
| Exelixis Clinical Site #12 | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Exelixis Clinical Site #120 | Córdoba | X5004 | Argentina | Details | ||
| Exelixis Clinical Site #121 | Kfar Saba | 4428164 | Israel | Details | ||
| Exelixis Clinical Site #122 | Hamilton | Waikato | 3204 | New Zealand | Details | |
| Exelixis Clinical Site #123 | Aguascalientes | Ags | 20116 | Mexico | Details | |
| Exelixis Clinical Site #124 | Dresden | 01307 | Germany | Details | ||
| Exelixis Clinical Site #125 | Rennes | 35042 | France | Details | ||
| Exelixis Clinical Site #126 | Vienna | 1090 | Austria | Details | ||
| Exelixis Clinical Site #127 | Heidelberg | Baden-Württemberg | 69120 | Germany | Details | |
| Exelixis Clinical Site #128 | Strasbourg | 67000 | France | Details | ||
| Exelixis Clinical Site #13 | Madison | Wisconsin | 53792 | United States | Details | |
| Exelixis Clinical Site #131 | Querétaro | 76000 | Mexico | Details | ||
| Exelixis Clinical Site #132 | Oaxaca de Juarez | Oaxaca | 68000 | Mexico | Details | |
| Exelixis Clinical Site #134 | Monterrey | Nuevo León | 64710 | Mexico | Details | |
| Exelixis Clinical Site #135 | Gdańsk | 80-219 | Poland | Details | ||
| Exelixis Clinical Site #136 | Shatin | Hong Kong | Details | |||
| Exelixis Clinical Site #137 | Jena | Thüringen | 077477 | Germany | Details | |
| Exelixis Clinical Site #138 | Taipei | 10002 | Taiwan | Details | ||
| Exelixis Clinical Site #139 | Münster | Nordrhein-Westfalen | 48149 | Germany | Details | |
| Exelixis Clinical Site #14 | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Exelixis Clinical Site #140 | Porto Alegre | Rio Grande Do Sul | 90110-270 | Brazil | Details | |
| Exelixis Clinical Site #141 | São Paulo | 01327-001 | Brazil | Details | ||
| Exelixis Clinical Site #142 | Taichung | 404 | Taiwan | Details | ||
| Exelixis Clinical Site #143 | Seoul | 03722 | Korea, Republic of | Details | ||
| Exelixis Clinical Site #144 | Amsterdam | 1105 AZ | Netherlands | Details | ||
| Exelixis Clinical Site #146 | Hasselt | 3500 | Belgium | Details | ||
| Exelixis Clinical Site #147 | Seongnam-si | Gyeonggi-do | 13620 | Korea, Republic of | Details | |
| Exelixis Clinical Site #148 | Newtown | Wellington | 6021 | New Zealand | Details | |
| Exelixis Clinical Site #149 | Rotterdam | 3015 GD | Netherlands | Details | ||
| Exelixis Clinical Site #15 | Detroit | Michigan | 48201 | United States | Details | |
| Exelixis Clinical Site #150 | Paris | 75015 | France | Details | ||
| Exelixis Clinical Site #151 | Seoul | 05505 | Korea, Republic of | Details | ||
| Exelixis Clinical Site #152 | Seoul | 06351 | Korea, Republic of | Details | ||
| Exelixis Clinical Site #153 | Pilar | Provincia De Buenos Aires | B1629ODT | Argentina | Details | |
| Exelixis Clinical Site #154 | Belo Horizonte | Minas Gerais | 30130-090 | Brazil | Details | |
| Exelixis Clinical Site #155 | Curitiba | Parana | 80530-010 | Brazil | Details | |
| Exelixis Clinical Site #158 | Porto Alegre | RS | 90050-170 | Brazil | Details | |
| Exelixis Clinical Site #159 | New York | New York | 10032 | United States | Details | |
| Exelixis Clinical Site #160 | Ciudad de México | 03100 | Mexico | Details | ||
| Exelixis Clinical Site #161 | Querétaro | 76090 | Mexico | Details | ||
| Exelixis Clinical Site #162 | São José Do Rio Preto | São Paulo | 15090-000 | Brazil | Details | |
| Exelixis Clinical Site #163 | Porto Alegre | Rio Grande Do Sul | 90610-000 | Brazil | Details | |
| Exelixis Clinical Site #164 | Mainz | Rheinland-Pfalz | 55131 | Germany | Details | |
| Exelixis Clinical Site #166 | Orange | California | 92868-3201 | United States | Details | |
| Exelixis Clinical Site #167 | León | Guanajuato | 37000 | Mexico | Details | |
| Exelixis Clinical Site #168 | Barretos | São Paulo | 14784-400 | Brazil | Details | |
| Exelixis Clinical Site #169 | Zapopan | Jalisco | 45070 | Mexico | Details | |
| Exelixis Clinical Site #17 | South Brisbane | Queensland | 4101 | Australia | Details | |
| Exelixis Clinical Site #171 | Münster | Nordrhein-Westfalen | 90419 | Germany | Details | |
| Exelixis Clinical Site #172 | London | W6 8RF | United Kingdom | Details | ||
| Exelixis Clinical Site #173 | Taoyuan | 333 | Taiwan | Details | ||
| Exelixis Clinical Site #18 | Adelaide | South Australia | 5000 | Australia | Details | |
| Exelixis Clinical Site #19 | Syracuse | New York | 13210 | United States | Details | |
| Exelixis Clinical Site #2 | Omaha | Nebraska | 68130 | United States | Details | |
| Exelixis Clinical Site #20 | Madrid | 28041 | Spain | Details | ||
| Exelixis Clinical Site #22 | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Exelixis Clinical Site #23 | Box Hill | Victoria | 3128 | Australia | Details | |
| Exelixis Clinical Site #24 | Kansas City | Missouri | 64132 | United States | Details | |
| Exelixis Clinical Site #25 | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Exelixis Clinical Site #26 | Subiaco | Western Australia | 6008 | Australia | Details | |
| Exelixis Clinical Site #27 | North Ryde | New South Wales | 2109 | Australia | Details | |
| Exelixis Clinical Site #28 | Hong Kong | Hong Kong | Details | |||
| Exelixis Clinical Site #29 | Boca Raton | Florida | 33486 | United States | Details | |
| Exelixis Clinical Site #3 | Atlanta | Georgia | 30318 | United States | Details | |
| Exelixis Clinical Site #30 | London | EC1A 7BE | United Kingdom | Details | ||
| Exelixis Clinical Site #31 | Biała Podlaska | 21-500 | Poland | Details | ||
| Exelixis Clinical Site #32 | Albury | New South Wales | 2640 | Australia | Details | |
| Exelixis Clinical Site #33 | Sydney | New South Wales | 2065 | Australia | Details | |
| Exelixis Clinical Site #34 | Madrid | 28009 | Spain | Details | ||
| Exelixis Clinical Site #35 | Kogarah | New South Wales | 2217 | Australia | Details | |
| Exelixis Clinical Site #36 | Barcelona | 08036 | Spain | Details | ||
| Exelixis Clinical Site #37 | Villejuif | 94800 | France | Details | ||
| Exelixis Clinical Site #38 | Nashville | Tennessee | 37232 | United States | Details | |
| Exelixis Clinical Site #39 | Budapest | 1122 | Hungary | Details | ||
| Exelixis Clinical Site #4 | Saint Louis | Missouri | 63110 | United States | Details | |
| Exelixis Clinical Site #40 | Singapore | 169610 | Singapore | Details | ||
| Exelixis Clinical Site #41 | Meldola | Forli - Cesena | 47014 | Italy | Details | |
| Exelixis Clinical Site #42 | Toulouse Cedex 9 | 31059 | France | Details | ||
| Exelixis Clinical Site #43 | Barcelona | 08035 | Spain | Details | ||
| Exelixis Clinical Site #44 | Miami | Florida | 33176 | United States | Details | |
| Exelixis Clinical Site #45 | Pamplona | Navarra | 31008 | Spain | Details | |
| Exelixis Clinical Site #46 | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Exelixis Clinical Site #47 | Arezzo | 52100 | Italy | Details | ||
| Exelixis Clinical Site #49 | Córdoba | 14004 | Spain | Details | ||
| Exelixis Clinical Site #5 | Myrtle Beach | South Carolina | 29572 | United States | Details | |
| Exelixis Clinical Site #50 | Helsinki | 00029 | Finland | Details | ||
| Exelixis Clinical Site #51 | Pécs | 7624 | Hungary | Details | ||
| Exelixis Clinical Site #52 | Turku | 20520 | Finland | Details | ||
| Exelixis Clinical Site #53 | Santiago De Compostela | Coruña | 15706 | Spain | Details | |
| Exelixis Clinical Site #54 | Ciudad Autonoma de Buenos Aires | C1125ABD | Argentina | Details | ||
| Exelixis Clinical Site #55 | Madrid | 28050 | Spain | Details | ||
| Exelixis Clinical Site #56 | Tampere | 33520 | Finland | Details | ||
| Exelixis Clinical Site #57 | Seattle | Washington | 98109 | United States | Details | |
| Exelixis Clinical Site #58A | Baltimore | Maryland | 21287 | United States | Details | |
| Exelixis Clinical Site #59 | Pavia | 27100 | Italy | Details | ||
| Exelixis Clinical Site #6 | Burlington | Massachusetts | 01805 | United States | Details | |
| Exelixis Clinical Site #60 | Modena | 41124 | Italy | Details | ||
| Exelixis Clinical Site #61 | Padova | 35128 | Italy | Details | ||
| Exelixis Clinical Site #62 | Bydgoszcz | 85-796 | Poland | Details | ||
| Exelixis Clinical Site #63 | Caba | C1120AAT | Argentina | Details | ||
| Exelixis Clinical Site #64 | Fairfax | Virginia | 22031 | United States | Details | |
| Exelixis Clinical Site #65 | Reims Cedex | 51726 | France | Details | ||
| Exelixis Clinical Site #66 | Nice Cedex 2 | 06189 | France | Details | ||
| Exelixis Clinical Site #67 | Vandœuvre-lès-Nancy | 54519 | France | Details | ||
| Exelixis Clinical Site #68 | Terni | 05100 | Italy | Details | ||
| Exelixis Clinical Site #69 | Scarborough | Maine | 04074 | United States | Details | |
| Exelixis Clinical Site #70 | Faenza | Ravenna | 48018 | Italy | Details | |
| Exelixis Clinical Site #71 | Le Mans | 72000 | France | Details | ||
| Exelixis Clinical Site #72 | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Exelixis Clinical Site #73 | San Miguel De Tucumán | Tucumán | T4000 | Argentina | Details | |
| Exelixis Clinical Site #74 | Valencia | 46009 | Spain | Details | ||
| Exelixis Clinical Site #75 | Salzburg | 5020 | Austria | Details | ||
| Exelixis Clinical Site #76 | Linz | Oberösterreich | 4020 | Austria | Details | |
| Exelixis Clinical Site #77 | Singapore | 119074 | Singapore | Details | ||
| Exelixis Clinical Site #78 | Lyon Cedex 8 | 69373 | France | Details | ||
| Exelixis Clinical Site #7A | Boston | Massachusetts | 02215 | United States | Details | |
| Exelixis Clinical Site #7B | Boston | Massachusetts | 02114 | United States | Details | |
| Exelixis Clinical Site #7C | Boston | Massachusetts | 02215 | United States | Details | |
| Exelixis Clinical Site #8 | New York | New York | 10065 | United States | Details | |
| Exelixis Clinical Site #80 | Montpellier Cedex 5 | 34295 | France | Details | ||
| Exelixis Clinical Site #81 | Haifa | 3109601 | Israel | Details | ||
| Exelixis Clinical Site #83 | Poznań | 60-693 | Poland | Details | ||
| Exelixis Clinical Site #84 | Jerusalem | 9112001 | Israel | Details | ||
| Exelixis Clinical Site #85 | Temuco | Región De La Araucanía (IX) | 4810561 | Chile | Details | |
| Exelixis Clinical Site #86 | Bordeaux | 33075 | France | Details | ||
| Exelixis Clinical Site #88 | Be'er Sheva | 84101 | Israel | Details | ||
| Exelixis Clinical Site #89 | Králová | 50005 | Czechia | Details | ||
| Exelixis Clinical Site #9 | Ballarat | Victoria | 3350 | Australia | Details | |
| Exelixis Clinical Site #90 | Strasbourg | 67200 | France | Details | ||
| Exelixis Clinical Site #91 | Santiago | 7500921 | Chile | Details | ||
| Exelixis Clinical Site #92 | Manchester | M20 4BX | United Kingdom | Details | ||
| Exelixis Clinical Site #93 | Glasgow | G12 0YN | United Kingdom | Details | ||
| Exelixis Clinical Site #94 | Madrid | 28040 | Spain | Details | ||
| Exelixis Clinical Site #95 | Chicago | Illinois | 60612 | United States | Details | |
| Exelixis Clinical Site #96 | Oviedo | 33011 | Spain | Details | ||
| Exelixis Clinical Site #97 | Petach Tikva | 49100 | Israel | Details | ||
| Exelixis Clinical Site #98 | Wiener Neustadt | Niederösterreich | 2700 | Austria | Details | |
| Exelixis Clinical Site #99 | Otwock | 05-400 | Poland | Details |
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