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| NCT ID | NCT03962543 |
| Title | MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas (ReNeu) |
| Acronym | ReNeu |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | SpringWorks Therapeutics, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | child | adult |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| AdventHealth Pediatric Oncology Hematology at Orlando | Orlando | Florida | 32804 | United States | Details | |
| Albany Medical Center | Albany | New York | 12208 | United States | Details | |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | United States | Details | |
| Children's Healthcare of Atlanta - Center for Advanced Pediatrics | Atlanta | Georgia | 30329 | United States | Details | |
| Children's Hospital at Montefiore | Bronx | New York | 10467 | United States | Details | |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | United States | Details | |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | United States | Details | |
| Children's Hospital of Orange County | Orange | California | 92868 | United States | Details | |
| Children's Hospital of Pittsburgh UPMC | Pittsburgh | Pennsylvania | 15224 | United States | Details | |
| Children's Hospital of The King's Daughters | Norfolk | Virginia | 23510 | United States | Details | |
| Children's Medical Center | Dallas | Texas | 75235 | United States | Details | |
| Children's National Medical Center | Washington | District of Columbia | 20010 | United States | Details | |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | United States | Details | |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | United States | Details | |
| Cook Children's Medical Center | Fort Worth | Texas | 76104 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Henry Ford Hospital | Detroit | Michigan | 48202 | United States | Details | |
| Henry-Joyce Cancer Clinic | Nashville | Tennessee | 37232 | United States | Details | |
| IU Health Brain Tumor Infusion Clinic | Indianapolis | Indiana | 46202 | United States | Details | |
| Johns Hopkins All Children's Hospital | Saint Petersburg | Florida | 33701 | United States | Details | |
| Kosair Charities Pediatric Clinical Research Unit | Louisville | Kentucky | 40202 | United States | Details | |
| Lucile Packard Children's Hospital Stanford | Palo Alto | California | 94304 | United States | Details | |
| MACC Fund Research Center | Milwaukee | Wisconsin | 53226 | United States | Details | |
| Mayo Clinic | Rochester | Minnesota | 55905 | United States | Details | |
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | United States | Details | |
| Nemours A. I. duPont Hospital for Children | Wilmington | Delaware | 19803 | United States | Details | |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | United States | Details | |
| Oregon Health and Science University | Portland | Oregon | 97239 | United States | Details | |
| Orlando Health, Inc. | Orlando | Florida | 32806 | United States | Details | |
| St. Joseph's Univeristy Medical Center | Paterson | New Jersey | 07503 | United States | Details | |
| Swedish Medical Center - Cherry Hill Campus | Seattle | Washington | 98122 | United States | Details | |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| UCLA Oncology Center | Los Angeles | California | 90095 | United States | Details | |
| UNC Medical Center | Chapel Hill | North Carolina | 27514 | United States | Details | |
| University of Alabama at Birmingham/Children's of Alabama | Birmingham | Alabama | 35233 | United States | Details | |
| University of California - Davis Comprehensive Cancer Center | Sacramento | California | 95817 | United States | Details | |
| University of California - Irvine Health | Orange | California | 92868-3201 | United States | Details | |
| University of Chicago Medical Centers | Chicago | Illinois | 60637 | United States | Details | |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | United States | Details | |
| University of Florida Clinical Research Center | Gainesville | Florida | 32610 | United States | Details | |
| University of Illinois Hospital and Health Systems | Chicago | Illinois | 60612 | United States | Details | |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | United States | Details | |
| University of Michigan CS Mott Children's Hospital | Ann Arbor | Michigan | 48109 | United States | Details | |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | United States | Details | |
| University of Oklahoma Health Sciences Center, Jimmy Everest Center for Cancer and Blood Disorders in Children | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| University of Utah, Center for Clinical and Translational Sciences | Salt Lake City | Utah | 84108 | United States | Details | |
| UVA Health, Division of Neuro-Oncology | Charlottesville | Virginia | 22903 | United States | Details | |
| Washington University School of Medicine-Siteman Cancer Center | Saint Louis | Missouri | 63110 | United States | Details |
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