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NCT ID NCT03975647
Title A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Seattle Genetics, Inc.
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | SWE | NLD | ITA | ISR | GBR | FRA | ESP | DNK | DEU | CHE | CAN | BEL | AUT | AUS

Facility Status City State Zip Country Details
University of South Alabama - Mitchell Cancer Institute Mobile Alabama 36604 United States Details
Ironwood Cancer & Research Centers - Chandler Chandler Arizona 85224 United States Details
Banner MD Anderson Cancer Center Gilbert Arizona 85234 United States Details
Cancer Treatment Centers of America / Western Regional Medical Center Goodyear Arizona 85338 United States Details
Arizona Oncology Associates, PC - HAL Phoenix Arizona 85016 United States Details
Arizona Oncology Associates, PC - HOPE Tucson Arizona 85710 United States Details
St. Bernards Medical Center Jonesboro Arkansas 72401 United States Details
City of Hope National Medical Center Duarte California 91010-3000 United States Details
California Cancer Associates for Research and Excellence Inc (cCARE) Encinitas California 92024 United States Details
St. Joseph Heritage Healthcare TRIO Fullerton California 92835 United States Details
Chao Family Comprehensive Cancer Center University of California Irvine Orange California 92868 United States Details
University of California Irvine - Newport Orange California 92868 United States Details
University of California Davis Sacramento California 95817 United States Details
San Francisco General Hospital San Francisco California 94110 United States Details
University of California, San Francisco | HDFCCC - Hematopoietic Malignancies San Francisco California 94134 United States Details
UCLA Department of Medicine - Hematology & Oncology Santa Monica California 90404 United States Details
Torrance Memorial Physician Network - TRIO Torrance California 90505 United States Details
Kaiser Permanente Medical Center Northern California Vallejo California 94589 United States Details
Rocky Mountain Cancer Centers - Aurora Aurora Colorado 80012 United States Details
University of Colorado Hospital / University of Colorado Aurora Colorado 80045-0510 United States Details
SCL Health Good Samaritan Medical Center Cancer Centers of Colorado Broomfield Colorado 80021 United States Details
University of Colorado Health Memorial Hospital Colorado Springs Colorado 80909 United States Details
Cancer Centers of Colorado - Denver Denver Colorado 80218 United States Details
Poudre Valley Health System (PVHS) Fort Collins Colorado 80524 United States Details
Helen F. Graham Cancer Center / Christiana Care Health Systems Newark Delaware 19713 United States Details
Lombardi Cancer Center / Georgetown University Medical Center Washington District of Columbia 20007 United States Details
Florida Cancer Specialists - South Region Fort Myers Florida 33901 United States Details
Baptist MD Anderson Cancer Center Jacksonville Florida 32207 United States Details
University of Miami Miami Florida 33136 United States Details
Miami Cancer Institute at Baptist Health, Inc. Miami Florida 33176 United States Details
AdventHealth Cancer Institute Orlando Florida 32804 United States Details
Orlando Health, Inc. TRIO Orlando Florida 32806 United States Details
Florida Cancer Specialists - North Region Saint Petersburg Florida 33705 United States Details
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612 United States Details
Florida Cancer Specialists - East West Palm Beach, FL (SCRI) West Palm Beach Florida 33401 United States Details
Winship Cancer Institute / Emory University School of Medicine Atlanta Georgia 30322 United States Details
Augusta University Augusta Georgia 30912 United States Details
Northside Hospital Canton Georgia 30115 United States Details
Kaiser Permanente Moanalua Medical Center Honolulu Hawaii 96819 United States Details
Kapi'olani Medical Center for Women and Children Honolulu Hawaii 96826 United States Details
Illinois Cancer Specialists - Arlington Heights Arlington Heights Illinois 60005 United States Details
Rush University Medical Center Chicago Illinois 60612 United States Details
University of Chicago Medical Center Chicago Illinois 60637-1470 United States Details
Illinois Cancer Care Peoria Illinois 61615 United States Details
Ft Wayne Medical Oncology and Hematology, Inc TRIO Fort Wayne Indiana 46804 United States Details
University of Kansas Medical Center Kansas City Kansas 66160 United States Details
CHI Saint Joseph Medical Group Cancer Care Center Lexington Kentucky 40509 United States Details
Ochsner Medical Center New Orleans Louisiana 70121 United States Details
University of Maryland Baltimore Maryland 21201 United States Details
Mercy Medical Center -Weinberg Center Baltimore Maryland 21202 United States Details
American Oncology Networks LLC Bethesda Maryland 20817 United States Details
Maryland Oncology Hematology, P.A. Rockville Maryland 20850 United States Details
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 United States Details
Dana Farber Cancer Institute Boston Massachusetts 02215 United States Details
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109 United States Details
Henry Ford Health System Detroit Michigan 48202 United States Details
Minnesota Oncology Hematology P.A. Minneapolis Minnesota 55404 United States Details
North Mississippi Medical Center Hematology Oncology - Tupelo Tupelo Mississippi 38801 United States Details
Saint Luke's Cancer Institute LLC Kansas City Missouri 64111 United States Details
HCA Midwest Health Kansas City Kansas City Missouri 64132 United States Details
Washington University in St Louis Saint Louis Missouri 63110 United States Details
St. Vincent Frontier Cancer Center Billings Montana 59102 United States Details
Nebraska Cancer Specialists Omaha Nebraska 68130 United States Details
Comprehensive Cancer Centers of Nevada Las Vegas Nevada 89169 United States Details
Summit Medical Group Florham Park New Jersey 07932 United States Details
Saint Barnabas Medical Center Cancer Center Livingston New Jersey 07039 United States Details
Rutgers Cancer Institute of New Jersey New Brunswick New Jersey 08903-2681 United States Details
New York Oncology Hematology, P.C. Albany New York 12206 United States Details
Stony Brook University Cancer Center Stony Brook New York 11794-7263 United States Details
UNC Lineberger Comprehensive Cancer Center / University of North Carolina Chapel Hill North Carolina 27599 United States Details
Levine Cancer Institute Charlotte North Carolina 28204 United States Details
Duke University Medical Center Durham North Carolina 27710 United States Details
Providence Portland Medical Center Portland Oregon 97213 United States Details
Oregon Health and Science University Portland Oregon 97239-3098 United States Details
Northwest Cancer Specialists, P.C. Tigard Oregon 97223 United States Details
University of Pennsylvania / Perelman Center for Advanced Medicine Philadelphia Pennsylvania 19104 United States Details
Cancer Treatment Centers of America / Eastern Regional Medical Center Philadelphia Pennsylvania 19124 United States Details
Brig Center for Cancer Care and Survivorship Knoxville Tennessee 37909 United States Details
Tennessee Oncology-Nashville/Sarah Cannon Research Institute Nashville Tennessee 37203 United States Details
Texas Oncology - Amarillo Amarillo Texas 79124 United States Details
Texas Oncology - Austin Central Austin Texas 78731 United States Details
Texas Oncology - DFW Bedford Texas 76022 United States Details
Texas Oncology - DFW Dallas Texas 75203 United States Details
Texas Oncology - Medical City Dallas Dallas Texas 75230 United States Details
Texas Oncology - DFW Dallas Texas 75246 United States Details
University of Texas Southwestern Medical Center Dallas Texas 75390 United States Details
The Center for Cancer and Blood Disorders: Fortworth Fort Worth Texas 76104 United States Details
Texas Oncology - Houston Memorial City Houston Texas 77024 United States Details
MD Anderson Cancer Center / University of Texas Houston Texas 77030-4095 United States Details
Baylor Clinic Houston Texas 77030 United States Details
Oncology Consultants, PA Houston Texas 77030 United States Details
Texas Oncology - San Antonio Medical Center San Antonio Texas 78240 United States Details
Huntsman Cancer Institute/University of Utah Salt Lake City Utah 84112 United States Details
Virginia Cancer Specialists, PC Fairfax Virginia 22031 United States Details
Saint Francis Hospital / Bon Secours - Virginia Midlothian Virginia 23114 United States Details
Peninsula Cancer Institute Newport News Virginia 23601 United States Details
Oncology & Hematology Associates of Southwest Virginia Inc dba Blue Ridge Cancer Care Salem Virginia 24153 United States Details
Swedish Cancer Institute - Edmonds Edmonds Washington 98026 United States Details
Swedish Cancer Institute - Issaquah Issaquah Washington 98029 United States Details
Swedish Cancer Institute Seattle Washington 98104 United States Details
Peter MacCallum Cancer Centre Melbourne Other 3000 Australia Details
Austin Health Melbourne Other 3084 Australia Details
Breast Cancer Research Centre Nedlands Other 6009 Australia Details
Mater Hospital Sydney Other 2060 Australia Details
Westmead Hospital Westmead Other 2145 Australia Details
LKH- Universitat Klinikum Graz Graz Other 8036 Austria Details
Medizinische Universitat Innsbruck Innsbruck Other 6020 Austria Details
LKH Salzburg, Universitatsklinikum der PMU Salzburg Other 5020 Austria Details
Medizinische Universitat Wien Vienna Other 1090 Austria Details
Klinik Ottakring Vienna Other 1160 Austria Details
Institut Jules Bordet Anderlecht Other B-1070 Belgium Details
Cliniques Universitaires Saint Luc Brussels Other 1200 Belgium Details
Grand Hôpital de Charleroi - Saint-Joseph Charleroi Other 6000 Belgium Details
Universitair Ziekenhuis Antwerpen Edegem Other 2650 Belgium Details
Academisch Ziekenhuis Groeninge Kortrijk Other 8500 Belgium Details
Universitair Ziekenhuis Leuven Leuven Other 3000 Belgium Details
CHU de Liege Liege Other 4000 Belgium Details
CHU UCL Namur-Site de Saint Elisabeth Namur Other 5000 Belgium Details
University of Alberta / Cross Cancer Institute Edmonton Alberta T6G 1Z2 Canada Details
Queen Elizabeth II Health Sciences Centre Halifax Nova Scotia B3H 2Y9 Canada Details
Cancer Centre of Southeastern Ontario At Kingston General Hospital Kingston Ontario K7L 5P9 Canada Details
London Health Sciences Centre - Victoria Hospital London Ontario N6A 5W9 Canada Details
University of Ottawa / Ottawa General Hospital Ottawa Ontario K1H 8L6 Canada Details
University Health Network, Princess Margaret Hospital Toronto Ontario M5G 2M9 Canada Details
Centre Hospitalier de l'Universite de Montreal Montreal Quebec H2X 3E4 Canada Details
Jewish General Hospital Montreal Quebec H3T 1E2 Canada Details
Saskatoon Cancer Centre Saskatoon Saskatchewan S7N 4H4 Canada Details
Hopital du Saint-Sacrement, CHU de Quebec-Universite Laval Quebec G1S 4L8 Canada Details
Cancer Hospital Chinese Academy of Medical Sciences Beijing City Other 100021 China Details
Peking University People's Hospital Beijing Other 100044 China Details
Jilin Province Cancer Hospital Changghun Other 130012 China Details
Hunan Cancer Hospital Changsha Other 410013 China Details
Sun Yat-sen University Cancer Center Guangzhou City Other 510060 China Details
Guangdong Provincial People's Hospital Guangzhou Other 510080 China Details
Zhejiang Cancer Hospital Hangzhou City Other 310022 China Details
First Affiliated Hospital of Zhejiang University Hangzhou City Other China Details
The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Other 0571 China Details
Shandong Cancer Hospital Jinan Other 250117 China Details
Gulou Hospital Affiliated to Nanjing University Medical College Nanjing Other 210008 China Details
Shengjing Hospital of China Medical University Shenyang City Other 110022 China Details
Tianjin Medical University - Cancer Institute & Hospital Tianjin Other 453000 China Details
Hubei Cancer Hospital Wuhan Other 430000 China Details
Wuhan University Wuhan Other 430060 China Details
The First Affiliated Hospital of Xi'an Jiaotong University Xi'an Other 710061 China Details
Xi'An International Medical Center Hospital Xi'An Other 710100 China Details
Xuzhou Central Hospital Xuzhou Other 221009 China Details
The Affiliated Hospital of Xuzhou Medical College Xuzhou Other 22100 China Details
The Affiliated Hospital of Guangdong Medical University Zhan Jiang City Other 524000 China Details
Henan Cancer Hospital Zhengzhou Other 45003 China Details
Zigong First People's Hospital Zigong City Other 643000 China Details
Bejing Hospital Bejing China Details
Center of Women and Children Hospital of Guangdong Province Guangzhou 511400 China Details
Nanchang Third Hospital Nanchang City 330009 China Details
Guangxi Medical University Affiliated Tumor Hospital Nanning 530021 China Details
Aalborg Universitetshospital Aalborg Other 9100 Denmark Details
Aarhus University Hospital Aarhus N Other 8200 Denmark Details
Rigs Hospiltalet Copenhagen Other 2100 Denmark Details
Herlev Hospital Herlev Other 2730 Denmark Details
Odense University Hospital Odense C Other 5000 Denmark Details
Sygehus Lillebaelt - Vejle Sygehus Vejle Other 7100 Denmark Details
University Hospital of Besancon Besancon cedex Other 25030 France Details
Hospital Center Regional University Morvan De Brest Brest Other 29200 France Details
Centre de Lutte contre le Cancer - Francois Baclesse Caen Cedex 5 Other 14076 France Details
Hopital Europeen Georges Pompidou Cedex 15 Other 75908 France Details
Center Georges Francois Leclerc Dijon Other 21000 France Details
Clinique Victor Hugo Le Mans Le Mans Other 72000 France Details
Centre Leon Berard - Centre regional de lutte contre le cancer Rhone-Alpes Lyon cedex 08 Other 69008 France Details
Institut Paoli Calmettes Marseille Other 13273 France Details
Hopital Saint-Louis / Service d'Hematologie Paris Cedex 10 Other 75475 France Details
Institute Curie - Centre de Lutte Contre Le Cancer CLCC de Paris Paris Other 75298 CEDEX 05 France Details
Centre Henri Becquerel / Centre Regional de Lutte Contre le Cancer Rouen Other 76038 France Details
Hopitaux Universitaires de Strasbourg Strasbourg Other 67200 France Details
Institut Claudius Regaud IUCT-O Toulouse Cedex 9 Other 31059 France Details
CHU Tours - Hopital Bretonneau TOURS Cedex 09 Other 37044 France Details
Helios Klinikum Berlin-Buch Berlin Other 13125 Germany Details
Stadtisches Klinikum Dessau Dessau-Rosslau Other 06847 Germany Details
Kliniken Essen-Mitte - Evang. Huyssens-Stiftung Essen Other 45136 Germany Details
CHOP GmbH Frankfurt Other 60389 Germany Details
Universitaetsklinikum Hamburg-Eppendorf (UKE) Hamburg Other 20246 Germany Details
Universitatsklinikum Heidelberg Heidelberg Other 69120 Germany Details
Universitatsklinikum Schleswig-Holstein Kiel Other 24105 Germany Details
InVO- Institut fUr Versorgungsforschung in der onkologie GbR Koblenz Other 56068 Germany Details
Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz Mainz Other 55101 Germany Details
Klinikum Rechts der Isar der Technischen Universitaet Muenchen Muenchen Other 81675 Germany Details
Klinikum der Universitat Munchen Munchen Other 80337 Germany Details
Sana Klinikum Offenbach GmbH Offenbach am Main Other 63069 Germany Details
University of Rostock Rostock Other 18059 Germany Details
Shaare Zedek Medical Center Jerusalem Other 9103102 Israel Details
Meir Medical Center Kfar Saba Other 44281 Israel Details
Rabin Medical Center Petach Tikva Other 49414 Israel Details
Kaplan Medical Center Rehovot Other 76100 Israel Details
Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi Bologna Other 40138 Italy Details
Fondazione del Piemonte per l'Oncologia - Istituto di Candiolo FPO - IRCCS Candiolo Other 10060 Italy Details
Irccs Irst Meldola Other 47014 Italy Details
Istituto Europeo di Oncologia Milano Other 20141 Italy Details
Seconda Università degli Studi di Napoli, AOU Napoli Other 80131 Italy Details
Nuovo Ospedale di Prato - Santo Stefano Prato Other 59100 Italy Details
Ospedale degli Infermi Rimini Other 47923 Italy Details
Policlinico Universitario Agostino Gemelli Roma Other 00168 Italy Details
Azienda Ospedaliera S. Maria di Terni Terni Other 05100 Italy Details
A.O.U. - Ospedali Riuniti di Ancona Torrette Other 60126 Italy Details
Chiba Cancer Center Chiba Other 260-8717 Japan Details
National Cancer Center Hospital Chuo-ku Other 104-0045 Japan Details
National Hospital Organization Kyushu Cancer Center Fukuoka-shi Other 811-1395 Japan Details
Hiroshima City Hiroshima Citizens Hospital Hiroshima Other 730-8518 Japan Details
University of Tsukuba Hospital Ibaraki Other 305-8576 Japan Details
Hakuaikai Sagara Hospital/Breast Surgery Kagosima Other 892-0833 Japan Details
Kameda General Hospital Kamogawa Other 296-8602 Japan Details
National Cancer Center Hospital East Kashiwa-shi Other 277-8577 Japan Details
Saitama Cancer Center Kitaadachi-gun Other 362-0806 Japan Details
Kumamoto Shinto General Hospital Kumamoto Other 862-8655 Japan Details
NHO Shikoku Cancer Center Matsuyama Other 791-0280 Japan Details
Aichi Cancer Center Nagoya-shi Other 464-8681 Japan Details
Hyogo College of Medicine Hospital Nishinomiya Other 730-8518 Japan Details
National Hospital Organization Osaka Osaka Other 540-0006 Japan Details
Osaka International Cancer Institute Osaka Other 541-8567 Japan Details
National Hospital Organization Hokkaido Cancer Center Sapporo Other 003-0804 Japan Details
Shizuoka Cancer Center Sunto-Gun Other 411-8777 Japan Details
The Cancer Institute Hospital of JFCR Tokyo Other 135-8550 Japan Details
Kanagawa Cancer Center Yokohama Other 241-8515 Japan Details
National Cancer Center Goyang-si Other 10408 Korea, Republic of Details
Seoul National University Bundang Hospital Seongnam-si Other 13605 Korea, Republic of Details
Korea University Anam Hospital Seoul Other 02841 Korea, Republic of Details
Seoul National University Hospital Seoul Other 03080 Korea, Republic of Details
Severance Hospital, Yonsei University Health System Seoul Other 03722 Korea, Republic of Details
Asan Medical Center - Oncology Seoul Other 05505 Korea, Republic of Details
Samsung Medical Center Seoul Other 06351 Korea, Republic of Details
Isala Ziekenhuis Zwolle AB Zwolle Other 8025 Netherlands Details
Netherlands Cancer Institute Amsterdam Other 1066 WX Netherlands Details
Amphia Ziekenhuis Breda Other 4818 CK Netherlands Details
Reinier de Graaf Hospital Delft Other 2625 Netherlands Details
University Medical Center Groningen Groningen Other 9713 GZ Netherlands Details
Martini Ziekenhuis Groningen Other 9728 Netherlands Details
Maastricht University Medical Center Maastricht Other 6229 HX Netherlands Details
Erasmus Medisch Centrum Daniel Den Hoed Rotterdam Other 3015GD Netherlands Details
National University Cancer Institute, Singapore Singapore Other 119228 Singapore Details
National Cancer Centre Singapore Singapore Other 169610 Singapore Details
Hospital del Mar Barcelona Other 08003 Spain Details
Hospital Universitari Vall d'Hebron Barcelona Other 08035 Spain Details
Hospital Universitario Reina Sofia Cordoba Other 14004 Spain Details
Hospital General Universitario Gregorio Marañon Madrid Other 28007 Spain Details
Hospital Ruber Internacional Madrid Other 28034 Spain Details
Hospital Clinico San Carlos Madrid Other 28040 Spain Details
Hospital Universitario HM Sanchinarro Madrid Other 28050 Spain Details
Hospital Universitario Virgen de la Victoria Malaga Other 29010 Spain Details
Hospital Universitario Son Espases Palma de Mallorca Other 07120 Spain Details
L'Institut Catala d'Oncologia Saint Joan Despi Other 08970 Spain Details
Hospital Universitario de Canarias San Cristóbal de la Laguna Other 38320 Spain Details
Hospital Universitario Virgen del Rocio Sevilla Other 41013 Spain Details
Hospital Clinico Universitario de Valencia Valencia Other 46010 Spain Details
Hospital Universitario Miguel Servet Zaragoza Other 50009 Spain Details
Goteborgs Universitet - Sahlgrenska Akademin - Institutionen For Kliniska Vetenskaper (Institute Of Clinical Sciences) Gothenburg Other SE-40530 Sweden Details
Ryhov Hospital Jonkoping Other 55185 Sweden Details
Skanes University Hospital - Universitetssjukhus Lund Other 22185 Sweden Details
Orebro University Hospital Orebro Other 70185 Sweden Details
Onkologklinike Sodersjukhuset Stockholm Other S-11883 Sweden Details
University Hospital Basel - Brustzentrum Basel Other 4031 Switzerland Details
Institute of Oncology of Southern Switzerland Bellinzona Other 6500 Switzerland Details
University Hospital Lausanne CHUV Lausanne Other 1011 Switzerland Details
Kantonsspital Winterthur (KSW) Winterthur Other 8400 Switzerland Details
National Cheng-Kung University Hospital Tainan Other 704 Taiwan Details
National Taiwan University Hospital Tainan Other 704 Taiwan Details
University Hospitals Birmingham NHS Foundation Trust Birmingham Other B15 2TH United Kingdom Details
Addenbrooke's Hospital Cambridge Other CB2 0QQ United Kingdom Details
The University of Edinburgh Edinburgh Other EH4 2XU United Kingdom Details
Oxford University Hospitals Headington Other OX3 7LE United Kingdom Details
The Royal Marsden NHS Foundation Trust (RM) London Other SW3 6JJ United Kingdom Details
Sarah Cannon Research Institute UK London Other W1G 6AD United Kingdom Details
Maidstone and Tunbridge Wells NHS Trust Maidstone Other ME16 9QQ United Kingdom Details
The Christie NHS Foundation Trust Manchester Other M20 4GJ United Kingdom Details
The Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle Upon Tyne Other NE7 7DN United Kingdom Details
Mount Vernon Hospital, UK Northwood Other HA6 2RN United Kingdom Details
The Royal Marsden Hospital (Surrey) Sutton Other SM2 5PT United Kingdom Details
Royal Cornwall Hospitals NHS Trust Truro Other TR1 3LQ United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field