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| NCT ID | NCT03989115 |
| Title | Dose-Escalation/Expansion of RMC-4630 and Cobimetinib in Relapsed/Refractory Solid Tumors and RMC-4630 and Osimertinib in EGFR Positive Locally Advanced/Metastatic NSCLC |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | Revolution Medicines, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Honor Health Research Institute | Scottsdale | Arizona | 85258 | United States | Details | |
| City of Hope | Duarte | California | 91010 | United States | Details | |
| UC Irvine - Chao Family Comprehensive Cancer Center | Orange | California | 92868 | United States | Details | |
| UC Davis Comprehensive Cancer Center | Sacramento | California | 95817 | United States | Details | |
| UC San Francisco - Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94115 | United States | Details | |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60611 | United States | Details | |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21287 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | United States | Details | |
| Ohio State University | Columbus | Ohio | 43210 | United States | Details | |
| University of Oklahoma - Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Providence Cancer Institute, Franz Clinic | Portland | Oregon | 97213 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Sarah Cannon Research Institute - Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | United States | Details | |
| Dell Seton Medical Center at University of Texas | Austin | Texas | 78712 | United States | Details | |
| Virginia Cancer Specialists (Fairfax) - USOR | Fairfax | Virginia | 22031 | United States | Details | |
| University of Wisconsin | Madison | Wisconsin | 53792 | United States | Details | |
| Severance Hospital Yonsei University Health System | Seoul | Seoul Teugbyeolsi | 03722 | Korea, Republic of | Details | |
| Seoul National University Hospital | Seoul | 110744 | Korea, Republic of | Details | ||
| Samsung Medical Center - PPDS | Seoul | 135-710 | Korea, Republic of | Details |