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NCT ID | NCT04102020 |
Title | A Safety and Efficacy Study of Oral Venetoclax Tablets and Injectable Azacitidine Versus Best Supportive Care as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy to Evaluate Improvement in Relapse-Free Survival (VIALE-M) |
Acronym | VIALE-M |
Recruitment | Active, not recruiting |
Gender | both |
Phase | Phase III |
Variant Requirements | No |
Sponsors | AbbVie |
Indications | |
Therapies | |
Age Groups: | senior | adult |
Covered Countries | USA | TUR | ITA | ISR | HUN | GRC | GBR | FRA | ESP | DEU | CZE | CAN | AUS |
Facility | Status | City | State | Zip | Country | Details |
---|---|---|---|---|---|---|
Mitchell Cancer Institute /ID# 216443 | Mobile | Alabama | 36604 | United States | Details | |
Compassionate Cancer Care Research Group - Fountain Valley /ID# 216156 | Fountain Valley | California | 92708-7501 | United States | Details | |
University of California, Los Angeles /ID# 219149 | Los Angeles | California | 90095 | United States | Details | |
Colorado Blood Cancer Institute /ID# 214280 | Denver | Colorado | 80218 | United States | Details | |
St. Alphonsus Regional Medical /ID# 216424 | Boise | Idaho | 83706 | United States | Details | |
Duplicate_Rush University Medical Center /ID# 218815 | Chicago | Illinois | 60612 | United States | Details | |
University of Kentucky Markey Cancer Center /ID# 215048 | Lexington | Kentucky | 40536-7001 | United States | Details | |
Duplicate_Norton Cancer Institute /ID# 216401 | Louisville | Kentucky | 40202-3700 | United States | Details | |
Tulane Medical Center - New Orleans /ID# 218166 | New Orleans | Louisiana | 70112-2600 | United States | Details | |
Ochsner Clinic Foundation-New Orleans /ID# 214583 | New Orleans | Louisiana | 70121 | United States | Details | |
Tufts Medical Center /ID# 216110 | Boston | Massachusetts | 02111-1552 | United States | Details | |
Massachusetts General Hospital /ID# 217307 | Boston | Massachusetts | 02114 | United States | Details | |
Duplicate_UMass Chan Medical School /ID# 218163 | Worcester | Massachusetts | 01655 | United States | Details | |
Saint Louis University Cancer Center /ID# 218164 | Saint Louis | Missouri | 63110-2539 | United States | Details | |
Oncology Hematology Associates (OHA) - Springfield /ID# 216351 | Springfield | Missouri | 65807-5287 | United States | Details | |
The John Theurer Cancer /ID# 215191 | Hackensack | New Jersey | 07601 | United States | Details | |
Rutgers Cancer Institute of New Jersey /ID# 239708 | New Brunswick | New Jersey | 08901 | United States | Details | |
Weill Cornell Medical College /ID# 214847 | New York | New York | 10065 | United States | Details | |
Providence Portland Medical Ct /ID# 216231 | Portland | Oregon | 97213-2933 | United States | Details | |
Fox Chase Cancer Center /ID# 239372 | Philadelphia | Pennsylvania | 19111 | United States | Details | |
UPMC Hillman Cancer Ctr /ID# 214051 | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
Duplicate_Prisma Health Cancer Institute-Faris Road /ID# 216066 | Greenville | South Carolina | 29605-4255 | United States | Details | |
St Francis Cancer Center /ID# 216115 | Greenville | South Carolina | 29607-5253 | United States | Details | |
Gibbs Cancer Center & Research /ID# 216192 | Spartanburg | South Carolina | 29303-3040 | United States | Details | |
Tennessee Oncology-Nashville Centennial /ID# 218757 | Nashville | Tennessee | 37203-1632 | United States | Details | |
Texas Oncology- Baylor Charles A. Sammons Cancer Center /ID# 214584 | Dallas | Texas | 75246-2003 | United States | Details | |
University of Texas MD Anderson Cancer Center /ID# 225201 | Houston | Texas | 77030 | United States | Details | |
St George Hospital /ID# 215416 | Kogarah | New South Wales | 2217 | Australia | Details | |
Liverpool Hospital /ID# 215415 | Liverpool | New South Wales | 2170 | Australia | Details | |
Shoalhaven District Memorial Hospital /ID# 221973 | Nowra | New South Wales | 2541 | Australia | Details | |
Wollongong Hospital /ID# 216071 | Wollongong | New South Wales | 2500 | Australia | Details | |
Gold coast University Hospital /ID# 214650 | SouthPort | Queensland | 4215 | Australia | Details | |
Toowoomba Hospital /ID# 217922 | Toowoomba | Queensland | 4350 | Australia | Details | |
Princess Alexandra Hospital /ID# 238753 | Woolloongabba | Queensland | 4102 | Australia | Details | |
Royal Adelaide Hospital /ID# 238754 | Adelaide | South Australia | 5000 | Australia | Details | |
Box Hill Hospital /ID# 217622 | Box Hill | Victoria | 3128 | Australia | Details | |
Barwon Health /ID# 217921 | Geelong | Victoria | 3220 | Australia | Details | |
Perth Blood Institute Ltd /ID# 217531 | Nedlands | Western Australia | 6009 | Australia | Details | |
Tom Baker Cancer Centre /ID# 214625 | Calgary | Alberta | T2N 4N2 | Canada | Details | |
Duplicate_University of Alberta Hospital - Division of Hematology /ID# 215656 | Edmonton | Alberta | T6G 2B7 | Canada | Details | |
Juravinski Cancer Centre /ID# 214623 | Hamilton | Ontario | L8V 1C3 | Canada | Details | |
London Health Sciences Center- University Hospital /ID# 216055 | London | Ontario | N6A 5W9 | Canada | Details | |
Ottawa Hospital Research Institute /ID# 214627 | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
Princess Margaret Cancer Centre /ID# 214624 | Toronto | Ontario | M5G 2M9 | Canada | Details | |
McGill University Health Center Research Institute /ID# 215984 | Montreal | Quebec | H4A 3J1 | Canada | Details | |
Beijing Friendship Hospital /ID# 216455 | Beijing | Beijing | 100032 | China | Details | |
Chinese PLA General Hospital /ID# 216286 | Beijing | Beijing | 100853 | China | Details | |
Guangdong Provincial People's Hospital /ID# 216284 | Guangzhou | Guangdong | 510080 | China | Details | |
Nanfang Hospital of Southern Medical University /ID# 215565 | Guangzhou | Guangdong | 510515 | China | Details | |
Peking University International Hospital /ID# 217439 | Beijing | Guizhou | 102206 | China | Details | |
Henan Cancer Hospital /ID# 215566 | Zhengzhou | Henan | 450008 | China | Details | |
Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 218046 | Wuhan | Hubei | 430022 | China | Details | |
Tongji Hospital Tongji Medical College of HUST /ID# 216456 | Wuhan | Hubei | 430030 | China | Details | |
Duplicate_Shanghai Tongji Hospital /ID# 218800 | Shanghai | Shanghai | 200065 | China | Details | |
Tangdu Hospital of The Fourth Military Medical University, PLA /ID# 216283 | Xi'an | Shanxi | 710038 | China | Details | |
West China Hospital, Sichuan University /ID# 216606 | Chengdu | Sichuan | 610041 | China | Details | |
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sc /ID# 215558 | Tianjin | Tianjin | 300020 | China | Details | |
The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 215564 | Hangzhou | Zhejiang | 310003 | China | Details | |
Fakultni Nemocnice Ostrava /ID# 214809 | Ostrava | Praha 17 | 708 52 | Czechia | Details | |
Fakultni nemocnice Brno /ID# 214807 | Brno | 613 00 | Czechia | Details | ||
Ustav hematologie a krevni transfuze /ID# 215137 | Praha | 128 00 | Czechia | Details | ||
CHU de Nice - Hôpital Archet 1 /ID# 217368 | Nice | Alpes-Maritimes | 06200 | France | Details | |
Duplicate_CHU Bordeaux - Hopital Haut Leveque /ID# 215150 | Pessac | Gironde | 33604 | France | Details | |
Hopital Avicenne - APHP /ID# 215152 | Bobigny | Ile-de-France | 93000 | France | Details | |
CHRU Tours - Hopital Bretonneau /ID# 216186 | Tours CEDEX 9 | Indre-et-Loire | 37044 | France | Details | |
CHRU Lille - Hopital Claude Huriez /ID# 217474 | Lille | Nord | 59037 | France | Details | |
CHU de Nantes - Hotel Dieu /ID# 217367 | Nantes | Pays-de-la-Loire | 44000 | France | Details | |
Centre Hospitalier de la Cote Basque /ID# 216185 | Bayonne | Pyrenees-Atlantiques | 64100 | France | Details | |
Centre Hospitalier du Mans /ID# 215148 | Le Mans CEDEX 9 | Sarthe | 72037 | France | Details | |
Institut Gustave Roussy /ID# 215158 | Villejuif Cedex | Val-de-Marne | 94805 | France | Details | |
Chu Angers /Id# 215151 | Angers | 49933 | France | Details | ||
Duplicate_Hopital Henri Mondor /ID# 215159 | Creteil | 94000 | France | Details | ||
Centre Hospitalier de Versailles André Mignot /ID# 215157 | Le Chesnay | 78150 | France | Details | ||
Klinikum Chemnitz gGmbH /ID# 216073 | Chemnitz | Saarland | 09116 | Germany | Details | |
Universitaetsklinikum Giessen und Marburg /ID# 214734 | Marburg | Saarland | 35043 | Germany | Details | |
Universitaetsklinikum Leipzig /ID# 214440 | Leipzig | Sachsen | 04103 | Germany | Details | |
Universitaetsklinikum Schleswig-Holstein Campus Luebeck /ID# 215173 | Lübeck | Schleswig-Holstein | 23538 | Germany | Details | |
Universitaetsklinikum Halle (Saale) /ID# 221109 | Halle (Saale) | 06120 | Germany | Details | ||
General Hospital of Athens Laiko /ID# 213869 | Athens | Attiki | 11527 | Greece | Details | |
University General Hospital Attikon /ID# 214298 | Athens | Attiki | 12462 | Greece | Details | |
University General Hospital of Heraklion PA.G.N.I /ID# 214075 | Heraklion | Kriti | 71500 | Greece | Details | |
General University Hospital of Alexandroupolis /ID# 213870 | Alexandroupolis | 68100 | Greece | Details | ||
General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 213872 | Athens | 10676 | Greece | Details | ||
University General Hospital of Patras /ID# 213871 | RION Patras Achaia | 26504 | Greece | Details | ||
Debreceni Egyetem-Klinikai Kozpont /ID# 214422 | Debrecen | Hajdu-Bihar | 4032 | Hungary | Details | |
Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 214426 | Kaposvár | Somogy | 7400 | Hungary | Details | |
Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz /ID# 214425 | Nyiregyhaza | Szabolcs-Szatmar-Bereg | 4400 | Hungary | Details | |
Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz /ID# 215644 | Szombathely | Vas | 9700 | Hungary | Details | |
Semmelweis Egyetem /ID# 214423 | Budapest | 1085 | Hungary | Details | ||
Tel Aviv Sourasky Medical Center /ID# 239698 | Tel Aviv | Tel-Aviv | 6423906 | Israel | Details | |
Shaare Zedek Medical Center /ID# 239699 | Jerusalem | Yerushalayim | 91031 | Israel | Details | |
Hadassah Medical Center-Hebrew University /ID# 239700 | Jerusalem | Yerushalayim | 91120 | Israel | Details | |
Rabin Medical Center /ID# 239696 | Haifa | 4941492 | Israel | Details | ||
Azienda Ospedaliera Universitaria Federico II /ID# 214278 | Napoli | L Aquila | 80131 | Italy | Details | |
ASST Grande Ospedale Metropolitano Niguarda /ID# 213946 | Milan | Milano | 20162 | Italy | Details | |
AOU Citta della Salute e della Scienza di Torino /ID# 214505 | Torino | Piemonte | 10126 | Italy | Details | |
Duplicate_Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona /ID# 213944 | Ancona | 60126 | Italy | Details | ||
IRCCS Azienda Ospedaliero-Universitaria di Bologna /ID# 213948 | Bologna | 40138 | Italy | Details | ||
ASST Spedali civili di Brescia /ID# 214580 | Brescia | 25123 | Italy | Details | ||
Duplicate_A.O.U. Policlinico G. Rodolico S.Marco- Presidio G.Rodolico /ID# 214802 | Catania | 95123 | Italy | Details | ||
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico /ID# 214826 | Milan | 20122 | Italy | Details | ||
Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli /ID# 213947 | Napoli | 80131 | Italy | Details | ||
Ospedale S.Eugenio /ID# 214277 | Rome | 00144 | Italy | Details | ||
Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital /ID# 215680 | Nagoya-shi | Aichi | 453-8511 | Japan | Details | |
Aichi Cancer Center Hospital /ID# 215284 | Nagoya-shi | Aichi | 464-8681 | Japan | Details | |
University of Fukui Hospital /ID# 215283 | Yoshida-gun | Fukui | 910-1104 | Japan | Details | |
National Hospital Organization Kyushu Cancer Center /ID# 214841 | Fukuoka-shi | Fukuoka | 811-1395 | Japan | Details | |
Kyushu University Hospital /ID# 215286 | Fukuoka-shi | Fukuoka | 812-8582 | Japan | Details | |
Hokkaido University Hospital /ID# 215938 | Sapporo-shi | Hokkaido | 060-8648 | Japan | Details | |
National Hospital Organization Mito Medical Center /ID# 214699 | Higashi Ibaraki-gun | Ibaraki | 311-3193 | Japan | Details | |
Tohoku University Hospital /ID# 214669 | Sendai-shi | Miyagi | 9808574 | Japan | Details | |
Nagasaki University Hospital /ID# 214916 | Nagasaki-shi | Nagasaki | 852-8501 | Japan | Details | |
Duplicate_Okayama University Hospital /ID# 214840 | Okayama-shi | Okayama | 700-8558 | Japan | Details | |
Osaka Metropolitan University Hospital /ID# 215225 | Osaka-shi | Osaka | 545-8586 | Japan | Details | |
Kindai University Hospital /ID# 214915 | Osakasayama-shi | Osaka | 589-8511 | Japan | Details | |
Saitama Medical University International Medical Center /ID# 214823 | Hidaka-shi | Saitama | 350-1298 | Japan | Details | |
NTT Medical Center Tokyo /ID# 214959 | Shinagawa-ku | Tokyo | 141-8625 | Japan | Details | |
Yamagata University Hospital /ID# 214698 | Yamagata-shi | Yamagata | 990-9585 | Japan | Details | |
Pusan National University Hospital /ID# 213941 | Busan | Busan Gwang Yeogsi | 49241 | Korea, Republic of | Details | |
Seoul National University Bundang Hospital /ID# 215549 | Seongnam-si | Gyeonggido | 13620 | Korea, Republic of | Details | |
Seoul National University Hospital /ID# 213943 | Seoul | Seoul Teugbyeolsi | 03080 | Korea, Republic of | Details | |
Samsung Medical Center /ID# 213940 | Seoul | Seoul Teugbyeolsi | 06351 | Korea, Republic of | Details | |
Pan American Center for Oncology Trials, LLC /ID# 214953 | Rio Piedras | 00935 | Puerto Rico | Details | ||
Clinic of Immunopathology, SRIFCI /ID# 217937 | Novosibirsk | Kurskaya Oblast | 630047 | Russian Federation | Details | |
Regional Clinical Hospital of Yaroslavl /ID# 214318 | Yaroslavl | Kurskaya Oblast | 150062 | Russian Federation | Details | |
Nizhny Novgorod Regional Clinical Hospital named N.A. Semashko /ID# 214309 | Nizhniy Novgorod | Nizhegorodskaya Oblast | 603126 | Russian Federation | Details | |
Academician I.P. Pavlov First St. Petersburg State Medical University /ID# 215393 | St. Petersburg | Sankt-Peterburg | 197101 | Russian Federation | Details | |
P. Hertsen Moscow Oncology Research Institute /ID# 214312 | Moscow | 125284 | Russian Federation | Details | ||
MMCC Kommunarka /ID# 215223 | Moscow | 129301 | Russian Federation | Details | ||
Almazov National Medical Research Centre /ID# 214306 | Sankt-Peterburg | 197341 | Russian Federation | Details | ||
Duplicate_Instituto Catalan de Oncologia (ICO) L'Hospitalet /ID# 214715 | Hospitalet de Llobregat | Barcelona | 08908 | Spain | Details | |
Hospital Universitario de Navarra /ID# 214788 | Pamplona | Navarra | 31008 | Spain | Details | |
Hospital Santa Creu i Sant Pau /ID# 214714 | Barcelona | 08041 | Spain | Details | ||
Duplicate_Hospital Universitario Reina Sofia /ID# 214786 | Cordoba | 14004 | Spain | Details | ||
Hospital Universitario Infanta Leonor /ID# 214843 | Madrid | 28031 | Spain | Details | ||
MD Anderson Madrid /ID# 214477 | Madrid | 28033 | Spain | Details | ||
Hospital Universitario Ramon y Cajal /ID# 214684 | Madrid | 28034 | Spain | Details | ||
Hospital Universitario Fundacion Jimenez Diaz /ID# 214933 | Madrid | 28040 | Spain | Details | ||
Hospital Universitario 12 de Octubre /ID# 214789 | Madrid | 28041 | Spain | Details | ||
Hospital Universitario Virgen de la Victoria /ID# 214713 | Malaga | 29010 | Spain | Details | ||
Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 213953 | Kaohsiung | Keelung | 807 | Taiwan | Details | |
National Taiwan University Hospital /ID# 213939 | Taipei City | Taipei | 100 | Taiwan | Details | |
China Medical University Hospital /ID# 213952 | Taichung | 40447 | Taiwan | Details | ||
Linkou Chang Gung Memorial Hospital /ID# 213951 | Taoyuan City | 333 | Taiwan | Details | ||
Gulhane Askeri Tip Academy /ID# 214242 | Ankara | Adana | 06010 | Turkey | Details | |
Karadeniz University /ID# 214241 | Trabzon | Adana | 61000 | Turkey | Details | |
Ankara Univ Medical Faculty /ID# 214239 | Ankara | 06590 | Turkey | Details | ||
Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty /ID# 215525 | Istanbul | 34098 | Turkey | Details | ||
Erciyes University Medical Faculty /ID# 214240 | Kayseri | 38039 | Turkey | Details | ||
University Hospitals Bristol /ID# 215911 | Bristol | Bristol, City Of | BS1 3NU | United Kingdom | Details | |
Leicester Royal Infirmary /ID# 215924 | Leicester | England | LE1 5WW | United Kingdom | Details | |
Barts Health NHS Trust /ID# 215909 | London | London, City Of | E1 2ES | United Kingdom | Details | |
Guys and St Thomas NHS Foundation Trust /ID# 215908 | London | London, City Of | SE1 9RT | United Kingdom | Details | |
Cardiff & Vale University Health Board /ID# 215906 | Cardiff | Wales | CF14 4XN | United Kingdom | Details | |
University Hospitals Birmingham NHS Foundation Trust /ID# 215910 | Birmingham | B15 2TH | United Kingdom | Details | ||
University College London Hospitals NHS Foundation Trust /ID# 215921 | London | NW1 2PG | United Kingdom | Details |