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| NCT ID | NCT04191499 |
| Title | A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Patients With PIK3CA-Mutant, Hormone Receptor-Positive, Her2-Negative, Locally Advanced or Metastatic Breast Cancer (INAVO120) |
| Acronym | INAVO120 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | NZL | ITA | HUN | GRC | GBR | FRA | ESP | DNK | DEU | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Beverly Hills Cancer Center | Beverly Hills | California | 90211 | United States | Details | |
| Massachusetts General Hospital. | Boston | Massachusetts | 02114 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Sarah Cannon Research Institute / Tennessee Oncology | Chattanooga | Tennessee | 37403 | United States | Details | |
| Sarah Cannon Research Institute / Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| Texas Oncology - Central South | Austin | Texas | 78731 | United States | Details | |
| Texas Tech University Health Sciences Center | El Paso | Texas | 79905 | United States | Details | |
| Texas Oncology - Northeast Texas | Tyler | Texas | 75702 | United States | Details | |
| Northwest Medical Specialties | Tacoma | Washington | 98405 | United States | Details | |
| Fundación CENIT para la Investigación en Neurociencias | Buenos Aires | C1125ABD | Argentina | Details | ||
| Centro Oncologico Korben | Ciudad Autonoma Buenos Aires | C1426AGE | Argentina | Details | ||
| Hosp Provincial D. Centenarios | Rosario | S2002KDS | Argentina | Details | ||
| Macquarie University Hospital | Macquarie Park | New South Wales | 2109 | Australia | Details | |
| Southern Medical Day Care Centre | Wollongong | New South Wales | 2500 | Australia | Details | |
| Mater Adult Hospital | South Brisbane | Queensland | 4101 | Australia | Details | |
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Western Health | Fitzroy | Victoria | 3065 | Australia | Details | |
| Peninsula and South Eastern Haematology and Oncology Group | Frankston | Victoria | 3199 | Australia | Details | |
| UZ Leuven Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| Santa Casa de Misericordia de Porto Alegre | Porto Alegre | Rio Grande Do Sul | 90050-170 | Brazil | Details | |
| Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda | Sao Paulo | São Paulo | 01317-001 | Brazil | Details | |
| Arthur J.E. Child Comprehensive Cancer Center-Calgary | Calgary | Alberta | T2N 5G2 | Canada | Details | |
| London Regional Cancer Program, London Health Sciences Centre, Baines Centre | London | Ontario | N6A 4L6 | Canada | Details | |
| Ottawa Hospital | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Princess Margaret Cancer Center | Toronto | Ontario | M5G 1Z5 | Canada | Details | |
| Hopital du Saint Sacrement | Quebec City | Quebec | G1S 4L8 | Canada | Details | |
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| The First Hospital of Jilin University | Changchun City | 130021 | China | Details | ||
| West China Hospital, Sichuan University | Chengdu | 610041 | China | Details | ||
| The First Affiliated Hospital, Chongqing Medical University | Chongqing | 400016 | China | Details | ||
| Fujian Medical University Union Hospital | Fujian | 350001 | China | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou | 510060 | China | Details | ||
| Zhejiang Cancer Hospital | Hangzhou | 310022 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University) | Nanjing City | 210029 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai City | 201315 | China | Details | ||
| Hebei Medical University Fourth Hospital | Shijiazhuang | 050035 | China | Details | ||
| Tianjin Cancer Hospital | Tianjin | 300060 | China | Details | ||
| Hubei Cancer Hospital | Wuhan | 430079 | China | Details | ||
| First Affiliated Hospital of Medical College of Xi'an Jiaotong University | Xi'an | 710061 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| Vejle Sygehus | Vejle | 7100 | Denmark | Details | ||
| Centre Jean Perrin Centre Regional de Lutte Contre Le Cancer D auvergne | Clermont-ferrand | 63003 | France | Details | ||
| Centre Georges Francois Leclerc | Dijon | 21079 | France | Details | ||
| Centre Oscar Lambret | Lille | 59020 | France | Details | ||
| Hopital Dupuytren | Limoges | 87042 | France | Details | ||
| Hopital Prive Jean Mermoz | Lyon | 69373 | France | Details | ||
| Institut régional du Cancer Montpellier | Montpellier | 34298 | France | Details | ||
| Institut Universitaire du Cancer de Toulouse-Oncopole | Toulouse | 31059 | France | Details | ||
| Israel-Georgian Medical Research Clinic Healthycore | Tbilisi | 0112 | Georgia | Details | ||
| Tbilisi Oncology Dispensary | Tbilisi | 0159 | Georgia | Details | ||
| Ambulantes Tumorzentrum Spandau | Berlin | 13581 | Germany | Details | ||
| Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH | Essen | 45136 | Germany | Details | ||
| Nationales Centrum für Tumorerkrankungen (NCT) | Heidelberg | 69120 | Germany | Details | ||
| Universitätsklinikum Mannheim | Mannheim | 68167 | Germany | Details | ||
| Klinikum Mutterhaus der Borromaeerinnen gGmbH | Trier | 54290 | Germany | Details | ||
| Universitätsfrauenklinik Ulm | Ulm | 89075 | Germany | Details | ||
| Anticancer Hospital Ag. Savas | Athens | 115 22 | Greece | Details | ||
| Univ General Hosp Heraklion | Heraklion | 711 10 | Greece | Details | ||
| Euromedical General Clinic of Thessaloniki | Thessaloniki | 546 45 | Greece | Details | ||
| Queen Mary Hospital | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hospital | Shatin | Hong Kong | Details | |||
| Orszagos Onkologiai Intezet | Budapest | 1122 | Hungary | Details | ||
| Uzsoki Utcai Korhaz | Budapest | 1145 | Hungary | Details | ||
| Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz-Rendelointezet | Szolnok | 5004 | Hungary | Details | ||
| Azienda Ospedaliera Universitaria Federico II | Napoli | Campania | 80131 | Italy | Details | |
| A.O. Universitaria Di Parma | Parma | Emilia-Romagna | 43100 | Italy | Details | |
| Az. Osp. Spedali Civili | Brescia | Lombardia | 25123 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | Lombardia | 20133 | Italy | Details | |
| Ospedale Santa Maria Annunziata | Bagno a Ripoli | Toscana | 50012 | Italy | Details | |
| IOV - Istituto Oncologico Veneto - IRCCS | Padova | Veneto | 35128 | Italy | Details | |
| Pusan National University Hospital | Busan | 49241 | Korea, Republic of | Details | ||
| Kyungpook National University Medical Center | Daegu | 41404 | Korea, Republic of | Details | ||
| National Cancer Center | Gyeonggi-do | 10408 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Gangnam Severance Hospital | Seoul | 06273 | Korea, Republic of | Details | ||
| Ewha Womans University Mokdong Hospital | Seoul | 07985 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 6351 | Korea, Republic of | Details | ||
| National Cancer Institute IKN | Putrajaya | Federal Territory OF Putrajaya | 62250 | Malaysia | Details | |
| Hospital Sultan Ismail | Johor Bahru | 81100 | Malaysia | Details | ||
| Sarawak General Hospital | Sarawak | 93586 | Malaysia | Details | ||
| Palmerston North Hospital | Palmerston North | 4442 | New Zealand | Details | ||
| Narodowy Instytut Onkologii Odzia? w Gliwicach | Gliwice | 44-102 | Poland | Details | ||
| Przychodnia Lekarska KOMED, Roman Karaszewski | Konin | 625000 | Poland | Details | ||
| Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad | Warszawa | 02-781 | Poland | Details | ||
| Centro Clinico Champalimaud | Lisboa | 1400-038 | Portugal | Details | ||
| IPO do Porto | Porto | 4200-072 | Portugal | Details | ||
| Moscow Clinical Scientific Center | Moscow | Moskovskaja Oblast | 111123 | Russian Federation | Details | |
| Blokhin Cancer Research Center | Moscow | Moskovskaja Oblast | 115552 | Russian Federation | Details | |
| LLC Medscan | Moskva | Moskovskaja Oblast | 119421 | Russian Federation | Details | |
| Clinical Hospital Lapino (LLC Haven) | Yudino | Moskovskaja Oblast | 143081 | Russian Federation | Details | |
| Medical Clinic "AB Medical group" | Saint Petersburg | Sankt Petersburg | 197082 | Russian Federation | Details | |
| Volgograd Regional Clinical Oncology Dispensary | Volgograd | 400138 | Russian Federation | Details | ||
| Regional Clinical Oncology Hospital | Yaroslavl | 150040 | Russian Federation | Details | ||
| National Cancer Centre | Singapore | 168583 | Singapore | Details | ||
| Hospital Universitari Germans Trias i Pujol | Badalona | Barcelona | 08916 | Spain | Details | |
| Clinica Universitaria de Navarra | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitario de Canarias | La Laguna | Tenerife | 38320 | Spain | Details | |
| Hospital del Mar | Barcelona | 08003 | Spain | Details | ||
| Vall d?Hebron Institute of Oncology (VHIO), Barcelona | Barcelona | 08035 | Spain | Details | ||
| Insituto Catalán de Oncologia (ICO) | Barcelona | 08907 | Spain | Details | ||
| Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico | Jaen | 23007 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon | Madrid | 28007 | Spain | Details | ||
| Clinica Universidad de Navarra-Madrid | Madrid | 28027 | Spain | Details | ||
| Hospital Clinico San Carlos | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario Puerta de Hierro | Madrid | 28222 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | 41009 | Spain | Details | ||
| Instituto Valenciano Oncologia | Valencia | 46009 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Kaohsiung Medical Uni Chung-Ho Hospital | Kaohsiung | 807 | Taiwan | Details | ||
| Chi-Mei Medical Centre | Tainan | 710 | Taiwan | Details | ||
| Veterans General Hospital | Taipei | 00112 | Taiwan | Details | ||
| National Taiwan Uni Hospital | Taipei | 100 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center | Taipei | 112 | Taiwan | Details | ||
| Tri-Service General Hospital, Division of General Surgery | Taipei | 114 | Taiwan | Details | ||
| Ramathibodi Hospital | Bangkok | 10400 | Thailand | Details | ||
| Maharaj Nakorn Chiang Mai Hospital | Chiang Mai | 50200 | Thailand | Details | ||
| Chulabhorn Hospital | Lak Si | 10210 | Thailand | Details | ||
| Songklanagarind Hospital | Songkhla | 90110 | Thailand | Details | ||
| Adana Baskent University Hospital | Adana | 01120 | Turkey | Details | ||
| Gulhane Training and Research Hospital | Ankara | 06010 | Turkey | Details | ||
| Ege University Medical Faculty | Bornova, ?zm?r | 35100 | Turkey | Details | ||
| Istanbul University Cerrahpasa Faculty of Medicine | Istanbul | 34098 | Turkey | Details | ||
| SI Institute of general&urgent surgery n/a Zaytseva V.T NAMSU | Kharkiv | Kharkiv Governorate | 61018 | Ukraine | Details | |
| Municipal Institution SubCarpathian Clinical Oncological Centre | Ivano-Frankivsk | KIEV Governorate | 76018 | Ukraine | Details | |
| Uzhhorod Central City Clinical Hospital | Uzhhorod | KIEV Governorate | 88000 | Ukraine | Details | |
| City Clinical Hospital #4 | Dnipropetrovsk | 49102 | Ukraine | Details | ||
| ME Kryviy Rih Oncology Dispensary of Dnipropetrovs?k Regional Council | Kryvyi Rih | 50048 | Ukraine | Details | ||
| Royal Marsden Hospital - Fulham | London | SW3 6JJ | United Kingdom | Details | ||
| Mount Vernon Hospital | Northwood | HA6 2RN | United Kingdom | Details | ||
| Churchill Hospital | Oxford | OX3 7LJ | United Kingdom | Details | ||
| Peterborough City Hospital, Edith Cavell Campus | Peterborough | PE3 9GZ | United Kingdom | Details | ||
| Derriford Hospital | Plymouth | PL6 8DH | United Kingdom | Details | ||
| Royal Marsden Hosp NHS Fnd | Sutton | SM2 5PT | United Kingdom | Details |