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| NCT ID | NCT04220866 |
| Title | Study of Intratumoral (IT) Ulevostinag (MK-1454) in Combination With Intravenous (IV) Pembrolizumab (MK-3475) Compared to IV Pembrolizumab Alone as the First Line Treatment of Metastatic or Unresectable, Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) (MK-1454-002) |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NOR | ISR | GBR | FRA | ESP | BRA | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCLA Hematology & Oncology ( Site 0005) | Los Angeles | California | 90095 | United States | Details | |
| University of California at San Francisco ( Site 0006) | San Francisco | California | 94158 | United States | Details | |
| Henry Ford Hospital ( Site 0012) | Detroit | Michigan | 48202 | United States | Details | |
| Washington University ( Site 0021) | Saint Louis | Missouri | 63110 | United States | Details | |
| Sanford Cancer Center Oncology Clinic ( Site 0014) | Sioux Falls | South Dakota | 57104 | United States | Details | |
| Huntsman Cancer Institute ( Site 0004) | Salt Lake City | Utah | 84112 | United States | Details | |
| Chris OBrien Lifehouse ( Site 0040) | Camperdown | New South Wales | 2050 | Australia | Details | |
| Calvary Central Districts Hospital ( Site 0042) | Elizabeth Vale | South Australia | 5112 | Australia | Details | |
| Monash Health-Monash Medical Centre ( Site 0041) | Clayton | Victoria | 3168 | Australia | Details | |
| Ordensklinikum Linz Gmbh - Barmherzige Schwestern ( Site 0051) | Linz | Oberosterreich | 4010 | Austria | Details | |
| Allgemeines Krankenhaus der Stadt Wien ( Site 0049) | Vienna/Wien | Wien | 1090 | Austria | Details | |
| SCRI-CCCIT GesmbH ( Site 0050) | Salzburg | 5020 | Austria | Details | ||
| Centro Regional Integrado de Oncologia ( Site 0062) | Fortaleza | Ceara | 60336-232 | Brazil | Details | |
| Hospital de Caridade de Ijui ( Site 0061) | Ijui | Rio Grande Do Sul | 98700-000 | Brazil | Details | |
| Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0058) | Sao Paulo | 01246-000 | Brazil | Details | ||
| Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 0064) | Sao Paulo | 01321-001 | Brazil | Details | ||
| Centre Antoine Lacassagne ( Site 0070) | Nice | Alpes-Maritimes | 06189 | France | Details | |
| Centre Leon Berard ( Site 0072) | Lyon | Auvergne | 69373 | France | Details | |
| IUCT - Oncopole ( Site 0069) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Centre Oscar Lambret ( Site 0071) | Lille | Nord | 59000 | France | Details | |
| Gustave Roussy ( Site 0068) | Villejuif | Val-de-Marne | 94800 | France | Details | |
| Chaim Sheba Medical Center ( Site 0076) | Ramat Gan | Tel Aviv | 5265601 | Israel | Details | |
| Rambam Medical Center ( Site 0077) | Haifa | 3109601 | Israel | Details | ||
| Hadassah Medical Center. Ein Kerem ( Site 0078) | Jerusalem | 9112001 | Israel | Details | ||
| Severance Hospital ( Site 0103) | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center ( Site 0104) | Seoul | 05505 | Korea, Republic of | Details | ||
| Haukeland Universitetssykehus, Klinisk forskningspost voksne ( Site 0086) | Bergen | Hordaland | 5021 | Norway | Details | |
| Oslo Universitetssykehus Radiumhospitalet ( Site 0085) | Oslo | 0379 | Norway | Details | ||
| H.U. Vall de Hebron ( Site 0112) | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinico de Barcelona ( Site 0116) | Barcelona | 08036 | Spain | Details | ||
| Hospital Universitario Ramon y Cajal ( Site 0115) | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario Virgen de la Victoria ( Site 0114) | Malaga | 29010 | Spain | Details | ||
| Royal Marsden NHS Foundation Trust ( Site 0031) | London | London, City Of | SW3 6JJ | United Kingdom | Details | |
| Royal Marsden Hospital Sutton-Surrey ( Site 0032) | Sutton | Surrey | SM2 5PT | United Kingdom | Details |