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| NCT ID | NCT04285567 |
| Title | A Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine And Rituximab (BR) in FIT Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without DEL (17P) or TP53 Mutation (CRISTALLO) |
| Acronym | CRISTALLO |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ITA | FRA | ESP | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Medical Center of Aurora | Aurora | Colorado | 80012 | United States | Details | |
| American Oncology Partners of Maryland, PA | Bethesda | Maryland | 20817 | United States | Details | |
| University of Tennessee Medical Center;Office of Clinical Trials | Knoxville | Tennessee | 37920 | United States | Details | |
| Oncology & Hematology Associates of Southwest Virginia, Inc._Goldschmidt | Roanoke | Virginia | 24014 | United States | Details | |
| Canberra Hospital | Canberra | Australian Capital Territory | 2605 | Australia | Details | |
| Liverpool Hospital | Liverpool | New South Wales | 2170 | Australia | Details | |
| Port Macquarie - Mid North Coast Cancer Institute | Port Macquarie | New South Wales | 2444 | Australia | Details | |
| Royal North Shore Hospital | St Leonards | New South Wales | 2065 | Australia | Details | |
| Royal Hobart Hospital | Hobart | Tasmania | 7000 | Australia | Details | |
| Monash Health;Haematology Research | Clayton | Victoria | 3168 | Australia | Details | |
| Peter MacCallum Cancer Centre;Clinical Haematology | Melbourne | Victoria | 3050 | Australia | Details | |
| Northern Hospital;Oncology and/or Hematology | Melbourne | Victoria | 3076 | Australia | Details | |
| Hopital Haut Leveque Chu de Bordeaux | Pessac | Aquitaine | 33600 | France | Details | |
| Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau;Hématologie et Thérapie Cellulaire | Tours | Indre-et-Loire | 37032 | France | Details | |
| Centre Hospitalier de Pérpignan;hématologie | Perpignan | Languedoc-Roussillon | 66046 | France | Details | |
| Hopital Claude Huriez - CHU de Lille;service maladies appareil digestif | Lille | Nord | 59037 | France | Details | |
| Centre Hospitalier intercommunal de Toulon La Seyne sur Mer | Toulon | Provence-Alpes-Côte-d'Azur | 83100 | France | Details | |
| centre hospitalier lyon sud;Service Hématologie | Pierre-Bénite | Rhône | 69310 | France | Details | |
| HENRI MONDOR HOSPITAL;Centre d'investigation clinique | Créteil | Val-de-Marne | 94000 | France | Details | |
| Centre Hospitalier Universitaire de Caen Normandie | Caen | 14000 | France | Details | ||
| Clinique Victor Hugo- CCS du Mans | Le Mans | 72000 | France | Details | ||
| Centre Hospitalier Universitaire de Poitiers | Poitiers | 86021 | France | Details | ||
| Centre Hospitalier Universitaire de Reims - Hôpital Robert Debré;Hématologie Clinique | Reims | 51092 | France | Details | ||
| Azienda Ospedaliero Universitaria;Ematologia | Modena | Emilia-Romagna | 41125 | Italy | Details | |
| Policlinico Umberto I | Roma | Lazio | 161 | Italy | Details | |
| Fondazione Policlinico Universitario Agostino Gemelli | Roma | Lazio | 168 | Italy | Details | |
| Ospedale San Martino;U.O. Clinica Ematologica | Genova | Liguria | 16132 | Italy | Details | |
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico;U.O.C Ematologia | Milano | Lombardia | 20122 | Italy | Details | |
| ASST Grande Ospedale Metropolitano Niguarda;Ematologia | Milan | Lombardia | 20162 | Italy | Details | |
| Azienda Ospedaliero Universitaria Maggiore della Carità;SCDU Ematologia | Novara | Piemonte | 28100 | Italy | Details | |
| Instituto Tumori Giovanni Paolo II;ONCOLOGIA MEDICA | Bari | Puglia | 70124 | Italy | Details | |
| Ospedale Vito Fazzi;U.O. Ematologia IV Piano Polo Oncologico | Lecce | Puglia | 73100 | Italy | Details | |
| AO Santa Maria della Misericordia | Perugia | Umbria | 6132 | Italy | Details | |
| Hospital Germans Trias i Pujol | Badalona | Barcelona | 8916 | Spain | Details | |
| COMPLEJO HOSPITALARIO DE NAVARRA;Servicio de Hematología | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitari Vall d'Hebron;Hematology | Barcelona | 8035 | Spain | Details | ||
| Hospital Universitario La Paz;Hematología | Madrid | 28015 | Spain | Details | ||
| Hospital General Universitario Morales Meseguer;Hematologia y Oncologia médica | Murcia | 30008 | Spain | Details | ||
| Hospital Universitario Virgen del Rocío;Unidad Onco-Hematología Pediátrica | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario de Toledo | Toledo | 45007 | Spain | Details |