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| NCT ID | NCT04285567 |
| Title | A Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine And Rituximab (BR) in FIT Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without DEL (17P) or TP53 Mutation (CRISTALLO) |
| Acronym | CRISTALLO |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ITA | FRA | ESP | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Medical Center of Aurora; Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | United States | Details | |
| Center For Cancer and Blood Disorders | Bethesda | Maryland | 20817 | United States | Details | |
| Maryland Oncology Hematology, P.A. | Columbia | Maryland | 21044 | United States | Details | |
| St. Vincent Frontier Cancer Center | Billings | Montana | 59102 | United States | Details | |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | United States | Details | |
| Texas Oncology West | Amarillo | Texas | 79106 | United States | Details | |
| Southwest Regional Cancer Center | Austin | Texas | 78705 | United States | Details | |
| Texas Oncology-Denton South | Denton | Texas | 76201 | United States | Details | |
| South Texas Cancer Center - McAllen | McAllen | Texas | 78503 | United States | Details | |
| Texas Oncology- Northeast Texas | Tyler | Texas | 75702 | United States | Details | |
| Community Cancer Trials of Utah | Ogden | Utah | 84405 | United States | Details | |
| Oncology & Hematolgy Associates of SW Va Inc. - Roanoke | Roanoke | Virginia | 24014 | United States | Details | |
| Canberra Hospital; Haematology Department | Canberra | Australian Capital Territory | 2605 | Australia | Details | |
| Liverpool Hospital; Haematology | Liverpool | New South Wales | 2170 | Australia | Details | |
| Port Macquarie Base Hospital | Port Macquarie | New South Wales | 2444 | Australia | Details | |
| Royal North Shore Hospital; Haematology Department | St. Leonards | New South Wales | 2065 | Australia | Details | |
| Royal Hobart Hospital | Hobart | Tasmania | 7000 | Australia | Details | |
| The Northern Hospital | Epping | Victoria | VIC 3076 | Australia | Details | |
| Peter MacCallum Cancer Centre; Department of Haematology | Melbourne | Victoria | 3002 | Australia | Details | |
| Monash Medical Centre; Haematology | Melbourne | Victoria | 3168 | Australia | Details | |
| CHU de Caen, Institut d'Hématologie de Basse-Normandie | Caen | 14033 | France | Details | ||
| Hopital Henri Mondor; Hematologie Clinique | Creteil | 94010 | France | Details | ||
| Clinique Victor Hugo- CCS du Mans | Le Mans | 72000 | France | Details | ||
| CHRU Lille - Hôpital Claude Huriez; Service des Maladies du Sang | Lille | 59037 | France | Details | ||
| Hopital Saint Jean : Pole Santé du Rousillon; Unité de Recherche clinique | Perpignan | 66046 | France | Details | ||
| Hopital De Haut Leveque; Hematologie Clinique | Pessac | 33604 | France | Details | ||
| Ch Lyon Sud; Hemato Secteur Jules Courmont | Pierre Benite | 69495 | France | Details | ||
| Hopital De La Miletrie; Hematologie Et Oncologie Medicale | Poitiers | 86021 | France | Details | ||
| Hopital Robert Debre; Hematologie Clinique | Reims | 51092 | France | Details | ||
| CHI de Toulon - Hôpital Sainte Musse | Toulon | 83056 | France | Details | ||
| Hopital Bretonneau; Hematologie Therapie Cellulaire | TOURS Cedex | 37044 | France | Details | ||
| Azienda Ospedaliero-Universitaria Policlinico di Modena Ematologia | Modena | Emilia-Romagna | 41123 | Italy | Details | |
| Universita' Degli Studi La Sapienza-Ist.Di Ematologia; Dip Biot Cel e Ematol | Roma | Lazio | 00161 | Italy | Details | |
| Uni Cattolica; Divisione Di Ematologia | Roma | Lazio | 00168 | Italy | Details | |
| A.O. Universitaria S. Martino Di Genova; Ematologia 1 | Genova | Liguria | 16132 | Italy | Details | |
| Ospedale Maggiore Di Milano; U.O. Ematologia I - Padiglione Marcora | Milano | Lombardia | 20122 | Italy | Details | |
| ASST GRANDE OSPEDALE METROPOLITANO NIGUARDA; Struttura Complessa di Ematologia | Milano | Lombardia | 20162 | Italy | Details | |
| SCDU Ematologia | Novara | Piemonte | 28100 | Italy | Details | |
| Irccs Ist. Tumori Giovanni Paolo Ii; Dipartimento Oncologia Medica | Bari | Puglia | 70124 | Italy | Details | |
| Asl Le-Ospedale "Vito Fazzi";U.O. Ematologia | Lecce | Puglia | 73100 | Italy | Details | |
| Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia; Oncologia Medica | Sant'Andrea Delle Fratte (PG) | Umbria | 06132 | Italy | Details | |
| Hospital Universitari Germans Trias i Pujol; Servicio de Hematologia | Badalona | Barcelona | 08915 | Spain | Details | |
| Hospital de Navarra, Servicio de Hematología | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitario de Canarias;servicio de Hematologia | La Laguna | Tenerife | 38320 | Spain | Details | |
| Hospital Universitario la Paz; Servicio de Hematologia | Madrid | 28046 | Spain | Details | ||
| Hospital General Universitario J.M Morales Meseguer; Servicio de Hematología | Murcia | 30008 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Hematologia | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitario de Toledo | Toledo | 45007 | Spain | Details |