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| NCT ID | NCT04404283 |
| Title | Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL (ECHELON-3) |
| Acronym | ECHELON-3 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Seagen Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | NLD | ITA | GBR | FRA | ESP | DNK | DEU | CZE | CHE | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Central Alabama Research | Birmingham | Alabama | 35209 | United States | Details | |
| Alabama Oncology | Birmingham | Alabama | 35223 | United States | Details | |
| Arizona Oncology Associates, PC - NAHOA | Goodyear | Arizona | 85395 | United States | Details | |
| The Oncology Institute of Hope & Innovation - California | Riverside | California | 92506 | United States | Details | |
| University of California Davis | Sacramento | California | 95817 | United States | Details | |
| Lundquist Institute/Harbor-UCLA | Torrance | California | 90502 | United States | Details | |
| Florida Cancer Specialists - South Region | Fort Myers | Florida | 33901 | United States | Details | |
| Florida Cancer Specialists - North Region | Saint Petersburg | Florida | 33705 | United States | Details | |
| Florida Cancer Specialists - East West Palm Beach, FL (SCRI) | West Palm Beach | Florida | 33401 | United States | Details | |
| Rush University Medical Center | Chicago | Illinois | 60612 | United States | Details | |
| Illinois Cancer Specialists | Niles | Illinois | 60714 | United States | Details | |
| University of Maryland | Baltimore | Maryland | 21201 | United States | Details | |
| Karmanos Cancer Institute / Wayne State University | Detroit | Michigan | 48201 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Cancer and Hematology Centers of Western Michigan / Lemmen-Holton Cancer Pavilion | Grand Rapids | Michigan | 49503 | United States | Details | |
| Ascension St John Hospital | Grosse Pointe Woods | Michigan | 48236 | United States | Details | |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| HCA Midwest Health Kansas City | Kansas City | Missouri | 64132 | United States | Details | |
| Saint Louis University | Saint Louis | Missouri | 63103 | United States | Details | |
| Washington University in St Louis | Saint Louis | Missouri | 63110 | United States | Details | |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-7680 | United States | Details | |
| MD Anderson Cancer Center at Cooper Health | Camden | New Jersey | 08103 | United States | Details | |
| Summit Medical Group | Florham Park | New Jersey | 07932 | United States | Details | |
| New York Cancer and Blood Specialists | Shirley | New York | 11967 | United States | Details | |
| Oncology Hematology Care | Cincinnati | Ohio | 45242 | United States | Details | |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45267 | United States | Details | |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | United States | Details | |
| Roper St. Francis Healthcare | Charleston | South Carolina | 29414 | United States | Details | |
| Medical University of South Carolina/Hollings Cancer Center | Charleston | South Carolina | 29425 | United States | Details | |
| Saint Francis Hospital / Bon Secours - South Carolina | Greenville | South Carolina | 29601 | United States | Details | |
| Prisma Health | Greenville | South Carolina | 29615 | United States | Details | |
| University of Tennessee | Knoxville | Tennessee | 37920 | United States | Details | |
| Texas Oncology - Austin Midtown | Austin | Texas | 78731 | United States | Details | |
| Texas Oncology - San Antonio Medical Center | San Antonio | Texas | 78240 | United States | Details | |
| University of Virginia | Charlottesville | Virginia | 22903 | United States | Details | |
| Northwest Cancer Specialists, P.C. | Vancouver | Washington | 98684 | United States | Details | |
| Carbone Cancer Center / University of Wisconsin | Madison | Wisconsin | 53792 | United States | Details | |
| Aurora Health Care, Inc | Wauwatosa | Wisconsin | 53226 | United States | Details | |
| Royal Adelaide Hospital | Adelaide | Other | 5000 | Australia | Details | |
| Central Coast Local Health District (Gosford and Wyong Hospitals) | Gosford | Other | 2250 | Australia | Details | |
| Royal Hobart Hospital | Hobart | Other | 7000 | Australia | Details | |
| Hollywood Haematology | Nedlands | Other | 6009 | Australia | Details | |
| Royal North Shore Hospital | Saint Leonards | Other | 2065 | Australia | Details | |
| Ziekenhuis Netwerk Antwerpen Campus Stuivenberg | Antwerpen | Other | 2060 | Belgium | Details | |
| Universitair Ziekenhuis Antwerpen | Edegem | Other | 2650 | Belgium | Details | |
| Universitair Ziekenhuis Gent | Gent | Other | 9000 | Belgium | Details | |
| CHU Helora Hopital de La Louviere Site Jolimont | Haine-Saint-Paul | Other | 7100 | Belgium | Details | |
| Clinique Saint Pierre | Ottignies | Other | 1340 | Belgium | Details | |
| AZ Delta - Campus Wilgenstraat | Roeselare | Other | 8800 | Belgium | Details | |
| CHU UCL Namur | Yvoir | Other | 5530 | Belgium | Details | |
| H. Bliss Murphy Cancer Centre / Eastern Regional Health Authority | St John's | Newfoundland and Labrador | A1B 3V6 | Canada | Details | |
| Queen Elizabeth II Health Sciences Centre | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details | |
| William Osler Health Sciences | East Brampton | Ontario | L6R 3J7 | Canada | Details | |
| London Health Sciences Centre - Victoria Hospital | London | Ontario | N6A 5W9 | Canada | Details | |
| Lakeridge Health - The R.S. McLaughlin Durham Regional Cancer Centre (MDRCC) | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| University of Ottawa / Ottawa General Hospital | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| CISSS de la Monteregie-Centre | Greenfield Park | Quebec | J4V 2H1 | Canada | Details | |
| CIUSSS de L'Est de l'lle de Montreal / installation Hopital Maisonneuve-Rosemont | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| CIUSS NIM/Hopital du Sacre-Coeur de Montreal | Montreal | Quebec | H4J 1C5 | Canada | Details | |
| Fakultni nemocnice Hradec Kralove-oddeleni klinicke hematologie | Hradec Kralove | Other | 500 05 | Czechia | Details | |
| Fakultni Nemocnice Kralovske Vinohrady | Praha 10 | Other | 100 34 | Czechia | Details | |
| Vseobecna fakultni nemocnice v Praze | Praha 2 | Other | 128 08 | Czechia | Details | |
| Aalborg Universitetshospital | Aalborg | Other | DK-9000 | Denmark | Details | |
| Aarhus University Hospital | Aarhus N | Other | 8200 | Denmark | Details | |
| Rigshospitalet | Copenhagen | Other | 2100 | Denmark | Details | |
| Zealand University Hospital (Roskilde Sygehus) | Roskilde | Other | 4000 | Denmark | Details | |
| Center Hospitalier Universitaire d' Angers | Angers Cedex 9 | Other | 49933 | France | Details | |
| Centre de Lutte Contre le Cancer (CLCC) - Institut Bergonie | Bordeaux | Other | 33076 | France | Details | |
| Centre Hospitalier Regional Universitaire (CHRU) Brest - Hopital Morvan | Brest Cedex | Other | 29609 | France | Details | |
| CHD Vendee, Site de La Roche-sur-Yon, Les Oudairies | Cedex 9 | Other | 85925 | France | Details | |
| Centre Hospitalier Metropole Savoie - Chambery | Chambery | Other | 73000 | France | Details | |
| Centre Hospitalier Sud Francilien | Corbeil-Essonnes | Other | 91100 | France | Details | |
| Centre Hospitalier Universitaire (CHU) Dijon Bourgogne | Dijon | Other | 21000 | France | Details | |
| Centre Hospitalier Universitaire de Grenoble | Grenoble | Other | 38043 CEDEX 9 | France | Details | |
| Centre Hospitalier Le Mans | Le Mans | Other | 72000 | France | Details | |
| Centre Hospitalier Universitaire (CHU) De Limoges - Hopital Dupuytren | Limoges Cedex | Other | 87042 | France | Details | |
| Centre Leon Berard - Centre regional de lutte contre le cancer Rhone-Alpes | Lyon | Other | 69373 | France | Details | |
| Centre Hospitalier Regional Metz-Thionville, Hopital Mercy | Metz | Other | 57085 | France | Details | |
| Hopital Emile Muller | Mulhouse | Other | 68100 | France | Details | |
| Centre Hospitalier Universitaire Nantes-Hotel Dieu | Nantes cedex 1 | Other | 44093 | France | Details | |
| Centre de Lutte contre le Cancer (CLCC) - Centre Antoine Lacassagne | Nice Cedex 2 | Other | 06189 | France | Details | |
| Centre Hospitalier de Perpignan | Perpignan CEDEX | Other | 66000 | France | Details | |
| CHU Bordeaux Hopital Haut-Leveque | Pessac Cedex | Other | 33600 | France | Details | |
| Centre Hospitalier Lyon Sud | Pierre-Benite Cedex | Other | 69495 | France | Details | |
| Centre Henri Becquerel / Centre Regional de Lutte Contre le Cancer | Rouen | Other | 76038 | France | Details | |
| Institut de Cancerologie Hematologie Universitaire de Saint Etienne (I.CHU.SE) | Saint Etienne Cedex 2 | Other | 42055 | France | Details | |
| Centre Hospitalier Universitaire de Nancy - Hopital de Brabois | Vandoeuvre-Les-Nancy Cedex 9 | Other | 54511 | France | Details | |
| Institut Gustave Roussy | Villejuif Cedex | Other | 94805 | France | Details | |
| CHU Tours - Hopital Bretonneau | Paris | 75012 | France | Details | ||
| Hopital Saint-Antoine | Paris | 75012 | France | Details | ||
| Medizinische Klinik & Poliklinik III (Bonn)nUniversitätsklinikum Bonn | Bonn | Other | 53127 | Germany | Details | |
| Stadtisches Klinikum Brandenburg GmbH | Brandenburg | Other | 14770 | Germany | Details | |
| Universitaetsklinikum Dusseldorf | Duesseldorf | Other | 40225 | Germany | Details | |
| Universitaetsklinikum Halle (Saale) | Halle (S.) | Other | 06120 | Germany | Details | |
| Centro di Riferimento Oncologico di Aviano | Aviano (Pordenone) | Other | 33081 | Italy | Details | |
| IRCCS Istituto Tumori Giovanni Paolo II | Bari | Other | 70124 | Italy | Details | |
| Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi | Bologna | Other | 40138 | Italy | Details | |
| Azienda Ospedaliero Universitaria Careggi | Firenze | Other | 50134 | Italy | Details | |
| Azienda Ospedaliera Universitaria San Martino | Genova | Other | 16132 | Italy | Details | |
| Azienda Ospedaliera Cardinale Giovanni Panico | Lecce | Other | 73039 | Italy | Details | |
| IRCCS Ospedale San Raffaele | Milano | Other | 20132 | Italy | Details | |
| Istituto Europeo di Oncologia | Milano | Other | 20141 | Italy | Details | |
| Azienda Ospedaliera Universitaria (AOU) Federico II | Napoli | Other | 80131 | Italy | Details | |
| AOOR Villa Sofia Cervello - Presidio V. Cervello | Palermo | Other | 90146 | Italy | Details | |
| Azienda Ospedaliero Universitaria di Parma | Parma | Other | 43126 | Italy | Details | |
| IRCSS Policlinico San Matteo | Pavia | Other | 27100 | Italy | Details | |
| Universita degli Studi di Perugia Azienda Ospedaliera di Perugia (Ospedale Santa Maria della Misericordia) | Perugia | Other | 06100 | Italy | Details | |
| UO Ematologia Ravenna | Ravenna | Other | 48121 | Italy | Details | |
| AUSL della Romagna Ospedale Infermi | Rimini | Other | 47923 | Italy | Details | |
| Policlinico Universitario Agostino Gemelli | Roma | Other | 00168 | Italy | Details | |
| IRCCS Ospedale Casa Sollievo della Sofferenza | San Giovanni Rotondo (Foggia) | Other | 71013 | Italy | Details | |
| Azienda Sanitaria Universitaria Giuliano Isontina | Trieste | Other | 34125 | Italy | Details | |
| Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico | Milano | 20122 | Italy | Details | ||
| Dong-A University Hospital | Busan | Other | 49201 | Korea, Republic of | Details | |
| Pusan National University Hospital | Busan | Other | 49241 | Korea, Republic of | Details | |
| Kosin University Gospel Hospital | Busan | Other | 49267 | Korea, Republic of | Details | |
| Inje University Busan-Paik Hospital | Busan | Other | 614-735 | Korea, Republic of | Details | |
| Keimyung University Dongsan Medical Center | Daegu | Other | 42601 | Korea, Republic of | Details | |
| National Cancer Center | Goyang-si | Other | 410-769 | Korea, Republic of | Details | |
| Gachon University Gil Medical Center | Incheon | Other | 21565 | Korea, Republic of | Details | |
| Jeonbuk National University Hospital | Jeonju-Si | Other | 561-712 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | Seoul | Other | 03722 | Korea, Republic of | Details | |
| Soon Chun Hyang University Hospital Seoul | Seoul | Other | 04401 | Korea, Republic of | Details | |
| Asan Medical Center - Oncology | Seoul | Other | 05505 | Korea, Republic of | Details | |
| Samsung Medical Center | Seoul | Other | 06351 | Korea, Republic of | Details | |
| Ewha Womans University Mokdong Hospital | Seoul | Other | 07985 | Korea, Republic of | Details | |
| Seoul Saint Mary's Hospital | Seoul | Other | 137-040 | Korea, Republic of | Details | |
| St. Vincent's Hospital, The Catholic University of Korea | Suwon-si | Other | 16247 | Korea, Republic of | Details | |
| Slingeland ziekenhuis | Doetinchem | Other | 7009 BL | Netherlands | Details | |
| Pratia Onkologia Katowice | Katowice | Other | 40-519 | Poland | Details | |
| Pratia MCM Krakow | Krakow | Other | 30-727 | Poland | Details | |
| Warmian-Masurian Cancer Center of The Ministry of The Interior and Administraton's Hospital | Olsztyn | Other | 10-228 | Poland | Details | |
| Pratia Poznan | Skorzewo | Other | 60185 | Poland | Details | |
| Nasz Lekarz Osrodek Badan Klinicznych | Torun | Other | 87-100 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy | Warsaw | Other | 02-781 | Poland | Details | |
| Hospital Universitari Germans Trias i Pujol | Badalona | Other | 08916 | Spain | Details | |
| Hospital del Mar | Barcelona | Other | 08003 | Spain | Details | |
| Hospital Universitari Vall d'Hebron | Barcelona | Other | 08035 | Spain | Details | |
| Hospital de la Santa Creu i Sant Pau | Barcelona | Other | 08041 | Spain | Details | |
| Hospital San Pedro de Alcantara | Caceres | Other | 10005 | Spain | Details | |
| Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet) | L'Hospitalet de Llobregat | Other | 08908 | Spain | Details | |
| Clinica Universidad de Navarra | Madrid | Other | 28027 | Spain | Details | |
| Hospital Universitario Infanta Leonor | Madrid | Other | 28031 | Spain | Details | |
| Hospital Puerta de Hierro Majadahonda | Madrid | Other | 28036 | Spain | Details | |
| Hospital Universitario Fundacion Jimenez Diaz | Madrid | Other | 28040 | Spain | Details | |
| Hospital Universitario 12 de Octubre | Madrid | Other | 28041 | Spain | Details | |
| Hospital Universitario La Paz | Madrid | Other | 28046 | Spain | Details | |
| Hospital Regional Universitario de Malaga - Hospital General | Malaga | Other | 29010 | Spain | Details | |
| Hospital Costa del Sol | Marbella | Other | 29603 | Spain | Details | |
| Hospital Universitario Central de Asturias | Oviedo | Other | 33011 | Spain | Details | |
| Complejo Hospitalario de Navarra | Pamplona | Other | 31008 | Spain | Details | |
| Hospital Universitario Quironsalud Madrid | Pozuelo de Alarcon | Other | 28223 | Spain | Details | |
| Hospital Clínico Universitario de Salamanca | Salamanca | Other | 37007 | Spain | Details | |
| Clinica Universidad de Navarra | Pamplona | 31008 | Spain | Details | ||
| Universitatsspital Basel | Basel | Other | 4031 | Switzerland | Details | |
| Kantonsspital Winterthur (KSW) | Winterthur | Other | 8401 | Switzerland | Details | |
| Universitatsspital Zurich | Zurich | Other | 8091 | Switzerland | Details | |
| Chang Gung Memorial Hospital - Kaohsiung | Kaohsiung | Other | 83301 | Taiwan | Details | |
| China Medical University Hospital | Taichung | Other | 404 | Taiwan | Details | |
| Chang Gung Memorial Hospital - Taoyuan | Tainan | Other | 704 | Taiwan | Details | |
| National Cheng-Kung University Hospital | Tainan | Other | 704 | Taiwan | Details | |
| Chi Mei Hospital Liouying | Tainan | Other | 73657 | Taiwan | Details | |
| National Taiwan University Hospital | Taipei | Other | 10002 | Taiwan | Details | |
| Taipei Veterans General Hospital | Taipei | Other | 11217 | Taiwan | Details | |
| East Sussex Healthcare NHS Trust | Eastbourne | Other | BN21 2UD | United Kingdom | Details | |
| University Hospitals Birmingham NHS Foundation Trust | Edgbaston, Birmingham | Other | B15 2TH | United Kingdom | Details | |
| St Bartholomew's Hospital | London | Other | EC1A 7BE | United Kingdom | Details | |
| Guy's and St Thomas' NHS Foundation | London | Other | SE1 9RT | United Kingdom | Details | |
| The Royal Marsden Hospital | London | Other | SW3 6JJ | United Kingdom | Details | |
| Maidstone and Tunbridge Wells NHS Trust | Maidstone | Other | ME16 9QQ | United Kingdom | Details | |
| The Royal Marsden Hospital (Surrey) | Sutton | Other | SM2 5PT | United Kingdom | Details | |
| Singleton Hospital | Swansea | Other | SA2 8QA | United Kingdom | Details |