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| NCT ID | NCT04436744 |
| Title | A Study Evaluating the Efficacy, Safety, and Pharmacokinetics of GDC-9545 Plus Palbociclib Compared With Anastrozole Plus Palbociclib for Postmenopausal Women With Estrogen Receptor-Positive and HER2-Negative Untreated Early Breast Cancer |
| Recruitment | Completed |
| Gender | female |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | HUN | ESP | DEU | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCLA - Burbank | Burbank | California | 91505 | United States | Details | |
| UCLA - Laguna Hills | Laguna Hills | California | 92653 | United States | Details | |
| UCLA Hematology/Oncology-San Luis Obispo | San Luis Obispo | California | 93401 | United States | Details | |
| UCLA Hematology Oncology-Santa Monica | Santa Monica | California | 90404 | United States | Details | |
| Torrance Memorial Physician Network/Cancer Care | Torrance | California | 90505 | United States | Details | |
| Orlando Health Inc. | Orlando | Florida | 32806 | United States | Details | |
| SCRI Florida Cancer Specialists East | West Palm Beach | Florida | 33401 | United States | Details | |
| Saint Barnabas Medical Center Cancer Center | Livingston | New Jersey | 07039 | United States | Details | |
| Tennessee Oncology; Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Univ of Wisconsin-Madison; Clinical Science Center | Madison | Wisconsin | 53762 | United States | Details | |
| Macquarie University Hospital | Macquarie Park | New South Wales | 2109 | Australia | Details | |
| Westmead Hospital; Medical Oncology and Pallative Care | Westmead | New South Wales | 2145 | Australia | Details | |
| Hospital do Cancer de Pernambuco - HCP | Recife | PE | 50040-000 | Brazil | Details | |
| Santa Casa de Misericordia de Porto Alegre | Porto Alegre | RS | 90050-170 | Brazil | Details | |
| Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda | Sao Paulo | SP | 01317-001 | Brazil | Details | |
| Núcleo de Pesquisa São Camilo; ONCOLOGIA CLINICA / QUIMIOTERAPIA | Sao Paulo | SP | 04014-002 | Brazil | Details | |
| Universitätsklinikum Dresden | Dresden | 01307 | Germany | Details | ||
| LUISENKRANKENHAUS; Senological Oncology | Düsseldorf | 40235 | Germany | Details | ||
| UNIVERSITATSKLINIKUM ERLANGEN; Department of Gynecology and Obstetrics | Erlangen | 91054 | Germany | Details | ||
| Bacs-Kiskun Megyei Korhaz, SZTE AOK Oktato Korhaza, Onkoradiologiai Kozpont; Onkoradiologiai Kozpont | Kecskemet | 6000 | Hungary | Details | ||
| Tolna Megyei Kórház, Onkológia | Szekszárd | 7100 | Hungary | Details | ||
| National Cancer Center; Medical Oncology | Gyeonggi-do | 410-769 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Severance Hospital; Internal Medicine | Seoul | 110-744 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 135-710 | Korea, Republic of | Details | ||
| The Catholic University of Korea Seoul St. Mary's Hospital | Seoul | 6591 | Korea, Republic of | Details | ||
| Szpital Morski Im. Pck; Oncology & Radiotherapy Dept | Gdynia | 81-519 | Poland | Details | ||
| COZL Oddzial Onkologii Klinicznej z pododdzialem Chemioterapii Dziennej | Lublin | 20-090 | Poland | Details | ||
| Centrum Onkologii - Inst.Im. Marii Sklodowskiej-Curie; Oncology | Warszawa | 02-781 | Poland | Details | ||
| DOLNOSLASKIE CENTRUM ONKOLOGII; Oddzial Chirurgii Piersi | Wrocław | 53-413 | Poland | Details | ||
| Moscow City Oncology Hospital #62 | Moscovskaya Oblast | Moskovskaja Oblast | 143423 | Russian Federation | Details | |
| Private Healthcare Institution Clinical Hospital RZhD Medicine | St. Petersburg | Sankt Petersburg | 195271 | Russian Federation | Details | |
| Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic | Kazan | Tatarstan | 420029 | Russian Federation | Details | |
| Filial #1 Regional Oncology Dispensary of Nizhniy Novgorod | Nizhny Novgorod | 603081 | Russian Federation | Details | ||
| S-Pb clinical scientific practical center of specialized kinds of medical care (oncological) | Saint-Petersburg | 197758 | Russian Federation | Details | ||
| FSI "SRC of Oncology n. a. N.N.Petrov of Rosmedtekhnologiy" | St. Petersburg | 197758 | Russian Federation | Details | ||
| Institutio Catalan De Oncologia | Badalona | Barcelona | 08916 | Spain | Details | |
| Complejo Hospitalario de Althaia; Servicio de Oncologia | Manresa | Barcelona | 08243 | Spain | Details | |
| Hospital de Jerez de la Frontera; Servicio de Oncologia | Jerez de La Frontera | Cadiz | 11407 | Spain | Details | |
| Hospital Universitari Arnau de Vilanova | Lleida | Lerida | 25198 | Spain | Details | |
| Hospital Universitario Puerta de Hierro Majadahonda | Majadahonda | Madrid | 28222 | Spain | Details | |
| Hospital Universitari Sant Joan de Reus; Planta baja, color lila | Reus | Tarragona | 43204 | Spain | Details | |
| Hospital Universitario de Canarias;servicio de Oncologia | La Laguna | Tenerife | 38320 | Spain | Details | |
| Hospital de la Santa Creu i Sant Pau | Barcelona | 08025 | Spain | Details | ||
| Hospital Universitario Quirón Dexeus | Barcelona | 08028 | Spain | Details | ||
| Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario Virgen de las Nieves : Hospital General | Granada | 18014 | Spain | Details | ||
| Hospital Clinico San Cecilio | Granada | 18016 | Spain | Details | ||
| Hospital Universitario Lucus Augusti | Lugo | 27003 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 280146 | Spain | Details | ||
| Fundación Jimenez Díaz | Madrid | 28040 | Spain | Details | ||
| Hosp Univ Fundacion Alcorcon | Madrid | 28922 | Spain | Details | ||
| Hospital Universitario Virgen de La Arrixaca | Murcia | 30120 | Spain | Details | ||
| Hospital de Navarra; Servicio de Oncologia | Navarra | 31008 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | 41009 | Spain | Details | ||
| Hospital General Universitario de Valencia | Valencia | 46014 | Spain | Details | ||
| National Cheng Kung Uni Hospital; Surgery | Tainan | 704 | Taiwan | Details | ||
| National Taiwan Uni Hospital; General Surgery | Taipei | 100 | Taiwan | Details | ||
| Regional Oncology Center of Kharkiv Regional Council; Department of Soft Tissues and Breast Cancer | Kharkiv | Kharkiv Governorate | 61070 | Ukraine | Details | |
| Odesa Regional Clinical Hospital; Department of Thoracic Surgery | Odesa | Kharkiv Governorate | 65025 | Ukraine | Details | |
| Khmelnytsky Regional Antitumor Center; Department of Breast, Skin, Soft Tissues and Bones Tumors | Khmelnytskyi | Podolia Governorate | 29009 | Ukraine | Details | |
| Municipal institution Dnipropetrovsk City Multifield Clinical Hospital #4; dept. of Chemotherapy | Dnipropetrovsk | 49102 | Ukraine | Details | ||
| ME Kryviy Rih Oncology Dispensary of Dnipropetrovs'k Regional Council; Chemotherapy Department | Kryvyi Rih | 50048 | Ukraine | Details | ||
| Kyiv Regional Oncological Dispensary | Kyiv | 04107 | Ukraine | Details |