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| NCT ID | NCT04485260 |
| Title | An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib |
| Recruitment | Unknown status |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | Kartos Therapeutics, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | ITA | ISR | FRA | ESP | DEU | BGR | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope | RECRUITING | Duarte | California | 91010 | United States | Details |
| John Hopkins University | RECRUITING | Baltimore | Maryland | 21205 | United States | Details |
| University of Michigan | RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| Icahn School of Medicine at Mount Sinai | RECRUITING | New York | New York | 10029 | United States | Details |
| Cleveland Clinic | RECRUITING | Cleveland | Ohio | 44106 | United States | Details |
| Fox Chase Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19111 | United States | Details |
| MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Fred Hutchinson Cancer Research Center | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| Royal Adelaide Hospital | RECRUITING | Adelaide | Australia | Details | ||
| Dr. Georgi Stranski | RECRUITING | Pleven | Bulgaria | Details | ||
| Saint Ivan Rilski Hospital | RECRUITING | Sofia | 1431 | Bulgaria | Details | |
| University Mutiprofile Hospital Alexandrovska | RECRUITING | Sofia | 1431 | Bulgaria | Details | |
| CHU de Caen | RECRUITING | Caen | Cedex 9 | 14033 | France | Details |
| Chu Angers | RECRUITING | Angers | 49933 | France | Details | |
| Centre Hospitalier du Mans | RECRUITING | Le Mans | 72000 | France | Details | |
| Institut Paoli-Calmettes | RECRUITING | Marseille | 13009 | France | Details | |
| CHU Saint Eloi | RECRUITING | Montpellier | 34295 | France | Details | |
| Hopital Saint Louis | RECRUITING | Paris | France | Details | ||
| CHU Tours - Hôpital Bretonneau | RECRUITING | Tours | France | Details | ||
| Universitätsklinikum Aachen Hämatologie, Onkologie, Hämostaseologie und Stammzelltransplantation | RECRUITING | Aachen | 52074 | Germany | Details | |
| Department für Innere Medizin Universitätsklinik und Poliklinik für Innere Medizin IV Hämatologie/Onkologie | RECRUITING | Halle | 6120 | Germany | Details | |
| Universitaetsklinikum Jena | RECRUITING | Jena | Germany | Details | ||
| UNIVERSITÄTSMEDIZIN der Johannes Gutenberg-Universität Mainz III. Med. Klinik und Poliklinik | RECRUITING | Mainz | 55131 | Germany | Details | |
| Stauferklinikum Schwäbisch Gmünd | RECRUITING | Mutlangen | 73557 | Germany | Details | |
| Shamir Medical Center ( Assaf Harofeh) | RECRUITING | Zerifin | 7033001 | Israel | Details | |
| Bologna University Hospital, Institute of Hematology | RECRUITING | Bologna | 340136 | Italy | Details | |
| Universita degli Studi di Catania | RECRUITING | Catania | 95124 | Italy | Details | |
| University of Florence | RECRUITING | Firenze | 50134 | Italy | Details | |
| Istituto Tumori della Romagna (IRST) | RECRUITING | Meldola | 47014 | Italy | Details | |
| Ospedale di Circolo e Fondazione MacchiASST Sette Laghi | RECRUITING | Varese | 21100 | Italy | Details | |
| Oddział Kliniczny Hematologii Szpitala Uniwersyteckiego w Krakowie | RECRUITING | Kraków | Poland | Details | ||
| Szpital Wojewódzki w Opolu Sp zooOddzial Kliniczny Hematologii | RECRUITING | Opole | Poland | Details | ||
| d'Hebron University Hospital in Barcelona | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Universitario Germans Trias i Pujol | RECRUITING | Barcelona | 08916 | Spain | Details | |
| Hospital Universitario de Gran Canaria Doctor Negrin | RECRUITING | Las Palmas De Gran Canaria | Spain | Details | ||
| Hospital Virgen de la Victoria | RECRUITING | Málaga | 29010 | Spain | Details | |
| Hospital Universitario de Salamanca | RECRUITING | Salamanca | Spain | Details | ||
| Hospital de Dia Quiron Zaragoza | RECRUITING | Zaragoza | 50012 | Spain | Details |