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| NCT ID | NCT04526106 |
| Title | REFOCUS: a First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients with ICC and Other Advanced Solid Tumors |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | Yes |
| Sponsors | Elevar Therapeutics |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | SWE | NLD | ITA | GBR | FRA | ESP | DEU | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | United States | Details | |
| Mayo Clinic | Phoenix | Arizona | 85054 | United States | Details | |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | United States | Details | |
| Mayo Clinic | Jacksonville | Florida | 32224 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| University of Michigan | Ann Arbor | Michigan | 48109 | United States | Details | |
| Mayo Clinic | Rochester | Minnesota | 55905 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Taussig Cancer Institute Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Texas Oncology | Dallas | Texas | 75246 | United States | Details | |
| The University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Huntsman Cancer Institute, University of Utah | Salt Lake City | Utah | 84112 | United States | Details | |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | United States | Details | |
| St. Vincent's Hosptial Sydney | Darlinghurst | 2010 | Australia | Details | ||
| Linear Clinical Research Ltd | Nedlands | 6009 | Australia | Details | ||
| Icon Cancer Care South Brisbane | South Brisbane, | 4101 | Australia | Details | ||
| Institut Bergonie | Bordeaux | 33076 | France | Details | ||
| Centre Georges François Leclerc | Dijon | 21079 | France | Details | ||
| Centre Leon Berard | Lyon | 69373 | France | Details | ||
| Gustave Roussy Cancer Campus | Paris | 94805 | France | Details | ||
| Medizinische Hochschule Hannover | Hannover | 30625 | Germany | Details | ||
| Universitätsklinikum Heidelberg | Heidelberg | 69120 | Germany | Details | ||
| LMU Klinikum, Campus Grosshadern | Munich | 81377 | Germany | Details | ||
| Queen Mary Hospital | Hong Kong | 999077 | Hong Kong | Details | ||
| Istituto Europeo di Oncologia | Milano | 20141 | Italy | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Netherlands Cancer institute | Amsterdam | 1066 CX | Netherlands | Details | ||
| Erasmus MC | Rotterdam | 3015 GD | Netherlands | Details | ||
| National Cancer Center Singapore | Singapore | 169610 | Singapore | Details | ||
| START Barcelona-Hospital HM Nou Delfos | Barcelona | 08023 | Spain | Details | ||
| Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario Fundación Jiménez Díaz- START MADRID | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario HM Sanchinarro-START MADRID-CIOCC | Madrid | 28050 | Spain | Details | ||
| Clinica de Universidad de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hospital Clínico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Karolinska University Hospital | Stockholm | 17176 | Sweden | Details | ||
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| Guy's Hospital | London | SE1 9RT | United Kingdom | Details | ||
| Sarah Cannon Research Institute UK | London | W1G 6AD | United Kingdom | Details | ||
| University College London Hospitals NHS Foundation Trust | London | W1T 7HA | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details |