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| NCT ID | NCT04543188 |
| Title | A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | Yes |
| Sponsors | Pfizer |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ISR | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Duarte | California | 91010 | United States | Details | |
| City of Hope Investigational Drug Services (IDS) | Duarte | California | 91010 | United States | Details | |
| Keck Hospital of USC | Los Angeles | California | 90033 | United States | Details | |
| LAC + USC Medical Center | Los Angeles | California | 90033 | United States | Details | |
| Norris Healthcare Center 3 (HC3) | Los Angeles | California | 90033 | United States | Details | |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| USC/Roski Eye Institute | Los Angeles | California | 90033 | United States | Details | |
| Keck Medical Center of USC Pasadena | Pasadena | California | 91105 | United States | Details | |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94143 | United States | Details | |
| UCSF Medical Center | San Francisco | California | 94158 | United States | Details | |
| Orlando Health Cancer Institute | Orlando | Florida | 32806 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Richard M Schulze Family Foundation Outpatient Center at McKinley Campus | Tampa | Florida | 33612 | United States | Details | |
| Northwestern Medical Group | Chicago | Illinois | 60611 | United States | Details | |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | United States | Details | |
| Community Health Network, Inc. | Indianapolis | Indiana | 46250 | United States | Details | |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | United States | Details | |
| The University of Kansas Cancer Center - Investigational Drug Services | Fairway | Kansas | 66205 | United States | Details | |
| The University of Kansas Clinical Research Center | Fairway | Kansas | 66205 | United States | Details | |
| The University of Kansas Hospital | Kansas City | Kansas | 66160 | United States | Details | |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205 | United States | Details | |
| Johns Hopkins University / Johns Hopkins Hospital | Baltimore | Maryland | 21231 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Ophthalmic Consultants of Boston Inc (OCB) | Boston | Massachusetts | 02114 | United States | Details | |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | United States | Details | |
| Imaging: Brigham and Women's Hospital | Boston | Massachusetts | 02115 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Imaging: Brigham and Women's Radiology, Coolidge Corner Imaging | Brookline | Massachusetts | 02446 | United States | Details | |
| Imaging: Brigham and Women's Ambulatory Care | Chestnut Hill | Massachusetts | 02467 | United States | Details | |
| Imaging: Brigham and Women's Mass General Healthcare Center | Foxboro | Massachusetts | 02035 | United States | Details | |
| Dana-Farber Cancer Institute - Chestnut Hill | Newton | Massachusetts | 02459 | United States | Details | |
| Michigan Health Professionals (PI Clinic) | Farmington Hills | Michigan | 48334 | United States | Details | |
| Revive Research Institute | Sterling Heights | Michigan | 48314 | United States | Details | |
| HealthPartners Cancer Center at Regions Hospital | Saint Paul | Minnesota | 55101 | United States | Details | |
| Regions Hospital Pharmacy | Saint Paul | Minnesota | 55101 | United States | Details | |
| Siteman Cancer Center - West County | Creve Coeur | Missouri | 63141 | United States | Details | |
| Siteman Cancer Center - North County | Florissant | Missouri | 63031 | United States | Details | |
| Barnes-Jewish Hospital | Saint Louis | Missouri | 63110 | United States | Details | |
| Washington University Infusion Center Pharmacy | Saint Louis | Missouri | 63110 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Siteman Cancer Center - South County | Saint Louis | Missouri | 63129 | United States | Details | |
| Siteman Cancer Center - St Peters | Saint Peters | Missouri | 63376 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| MSK Monmouth. | Middletown | New Jersey | 07748 | United States | Details | |
| MSK Commack | Commack | New York | 11725 | United States | Details | |
| MSKCC-Westchester (500 Westchester Ave.) | Harrison | New York | 10604 | United States | Details | |
| Laura and Isaac Perlmutter Cancer Center | New York | New York | 10016 | United States | Details | |
| NYU Langone Health | New York | New York | 10016 | United States | Details | |
| NYU Langone Medical Center (Tisch Hospital) | New York | New York | 10016 | United States | Details | |
| NYU Langone Radiology- ACC East 41st street | New York | New York | 10017 | United States | Details | |
| Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street). | New York | New York | 10021 | United States | Details | |
| Memorial Sloan Kettering Cancer Center Rockefeller Outpatient Pavilion | New York | New York | 10022 | United States | Details | |
| Rockefeller Outpatient Pavilion (53rd Street) | New York | New York | 10022 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| UNC Cancer Hospital Infusion Pharmacy | Chapel Hill | North Carolina | 27514 | United States | Details | |
| UNC Hospitals, The University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27514 | United States | Details | |
| Duke Eye Center | Durham | North Carolina | 27705 | United States | Details | |
| Duke University Medical Center, Investigational Chemotherapy Services | Durham | North Carolina | 27710 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Carl & Edyth Lindner Center for Research & Education at TCH and TCH Cancer Center | Cincinnati | Ohio | 45219 | United States | Details | |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | United States | Details | |
| West Chester Hospital | West Chester | Ohio | 45069 | United States | Details | |
| Tennessee Oncology PLLC | Franklin | Tennessee | 37067 | United States | Details | |
| Sarah Cannon Research Institute - Pharmacy | Nashville | Tennessee | 37203 | United States | Details | |
| Tennessee Oncology PLLC | Nashville | Tennessee | 37203 | United States | Details | |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030-4009 | United States | Details | |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Wisconsin Hospitals and Clinics | Madison | Wisconsin | 53792 | United States | Details | |
| Hamilton Health Sciences-Juravinski Cancer Centre | Hamilton | Ontario | L8V5C2 | Canada | Details | |
| Sunnybrook Research Institute | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Rambam Health Care Campus | Haifa | ?eif? | 3109601 | Israel | Details | |
| Rabin Medical Center | Petah-Tikva | Hamerkaz | 49100 | Israel | Details | |
| Sheba Medical Center | Ramat Gan | Hamerkaz | 5262100 | Israel | Details | |
| Sourasky Medical Center | Tel Aviv | Tell Abīb | 6423906 | Israel | Details | |
| Hadassah Medical Center | Jerusalem | Yerushalayim | 9112001 | Israel | Details |