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| NCT ID | NCT04576117 |
| Title | A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | child | adult |
| Covered Countries | USA | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Albany Medical Center | RECRUITING | Albany | New York | 12208 | United States | Details |
| Alfred I duPont Hospital for Children | RECRUITING | Wilmington | Delaware | 19803 | United States | Details |
| Arkansas Children's Hospital | RECRUITING | Little Rock | Arkansas | 72202-3591 | United States | Details |
| Arnold Palmer Hospital for Children | RECRUITING | Orlando | Florida | 32806 | United States | Details |
| Ascension Saint Vincent Indianapolis Hospital | RECRUITING | Indianapolis | Indiana | 46260 | United States | Details |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| BI-LO Charities Children's Cancer Center | RECRUITING | Greenville | South Carolina | 29605 | United States | Details |
| British Columbia Children's Hospital | RECRUITING | Vancouver | British Columbia | V6H 3V4 | Canada | Details |
| C S Mott Children's Hospital | RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| CancerCare Manitoba | RECRUITING | Winnipeg | Manitoba | R3E 0V9 | Canada | Details |
| Cardinal Glennon Children's Medical Center | RECRUITING | Saint Louis | Missouri | 63104 | United States | Details |
| Carolinas Medical Center/Levine Cancer Institute | RECRUITING | Charlotte | North Carolina | 28203 | United States | Details |
| Centre Hospitalier Universitaire de Sherbrooke-Fleurimont | RECRUITING | Sherbrooke | Quebec | J1H 5N4 | Canada | Details |
| Centre Hospitalier Universitaire Sainte-Justine | RECRUITING | Montreal | Quebec | H3T 1C5 | Canada | Details |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital | RECRUITING | Atlanta | Georgia | 30329 | United States | Details |
| Children's Hospital and Medical Center of Omaha | RECRUITING | Omaha | Nebraska | 68114 | United States | Details |
| Children's Hospital Colorado | RECRUITING | Aurora | Colorado | 80045 | United States | Details |
| Children's Hospital Los Angeles | RECRUITING | Los Angeles | California | 90027 | United States | Details |
| Children's Hospital Medical Center of Akron | RECRUITING | Akron | Ohio | 44308 | United States | Details |
| Children's Hospital New Orleans | RECRUITING | New Orleans | Louisiana | 70118 | United States | Details |
| Children's Hospital of Alabama | RECRUITING | Birmingham | Alabama | 35233 | United States | Details |
| Children's Hospital of Eastern Ontario | RECRUITING | Ottawa | Ontario | K1H 8L1 | Canada | Details |
| Children's Hospital of Michigan | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Children's Hospital of Orange County | RECRUITING | Orange | California | 92868 | United States | Details |
| Children's Hospital of Philadelphia | RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Children's Hospital of Pittsburgh of UPMC | RECRUITING | Pittsburgh | Pennsylvania | 15224 | United States | Details |
| Children's Hospital of San Antonio | RECRUITING | San Antonio | Texas | 78207 | United States | Details |
| Children's Hospital of The King's Daughters | RECRUITING | Norfolk | Virginia | 23507 | United States | Details |
| Children's Hospital of Wisconsin | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | RECRUITING | Minneapolis | Minnesota | 55404 | United States | Details |
| Children's Mercy Hospitals and Clinics | RECRUITING | Kansas City | Missouri | 64108 | United States | Details |
| Children's National Medical Center | RECRUITING | Washington | District of Columbia | 20010 | United States | Details |
| CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL) | RECRUITING | Quebec | G1V 4G2 | Canada | Details | |
| Cincinnati Children's Hospital Medical Center | RECRUITING | Cincinnati | Ohio | 45229 | United States | Details |
| Connecticut Children's Medical Center | RECRUITING | Hartford | Connecticut | 06106 | United States | Details |
| Cook Children's Medical Center | RECRUITING | Fort Worth | Texas | 76104 | United States | Details |
| Corewell Health Children's | RECRUITING | Royal Oak | Michigan | 48073 | United States | Details |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | RECRUITING | Grand Rapids | Michigan | 49503 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Dayton Children's Hospital | RECRUITING | Dayton | Ohio | 45404 | United States | Details |
| Dell Children's Medical Center of Central Texas | RECRUITING | Austin | Texas | 78723 | United States | Details |
| Duke University Medical Center | RECRUITING | Durham | North Carolina | 27710 | United States | Details |
| East Carolina University | RECRUITING | Greenville | North Carolina | 27834 | United States | Details |
| East Tennessee Childrens Hospital | RECRUITING | Knoxville | Tennessee | 37916 | United States | Details |
| Golisano Children's Hospital of Southwest Florida | RECRUITING | Fort Myers | Florida | 33908 | United States | Details |
| Hospital for Sick Children | RECRUITING | Toronto | Ontario | M5G 1X8 | Canada | Details |
| IWK Health Centre | RECRUITING | Halifax | Nova Scotia | B3K 6R8 | Canada | Details |
| Johns Hopkins All Children's Hospital | RECRUITING | Saint Petersburg | Florida | 33701 | United States | Details |
| Johns Hopkins University/Sidney Kimmel Cancer Center | RECRUITING | Baltimore | Maryland | 21287 | United States | Details |
| Kaiser Permanente-Oakland | RECRUITING | Oakland | California | 94611 | United States | Details |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | SUSPENDED | New York | New York | 10016 | United States | Details |
| Loma Linda University Medical Center | RECRUITING | Loma Linda | California | 92354 | United States | Details |
| Lucile Packard Children's Hospital Stanford University | RECRUITING | Palo Alto | California | 94304 | United States | Details |
| Lurie Children's Hospital-Chicago | RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| M D Anderson Cancer Center | SUSPENDED | Houston | Texas | 77030 | United States | Details |
| Madigan Army Medical Center | RECRUITING | Tacoma | Washington | 98431 | United States | Details |
| Maine Children's Cancer Program | RECRUITING | Scarborough | Maine | 04074 | United States | Details |
| Mayo Clinic in Rochester | RECRUITING | Rochester | Minnesota | 55905 | United States | Details |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital | RECRUITING | Hollywood | Florida | 33021 | United States | Details |
| Memorial Sloan Kettering Cancer Center | ACTIVE_NOT_RECRUITING | New York | New York | 10065 | United States | Details |
| Morristown Medical Center | RECRUITING | Morristown | New Jersey | 07960 | United States | Details |
| Nationwide Children's Hospital | RECRUITING | Columbus | Ohio | 43205 | United States | Details |
| Nemours Children's Clinic-Jacksonville | RECRUITING | Jacksonville | Florida | 32207 | United States | Details |
| Nemours Children's Hospital | RECRUITING | Orlando | Florida | 32827 | United States | Details |
| New York Medical College | RECRUITING | Valhalla | New York | 10595 | United States | Details |
| Norton Children's Hospital | RECRUITING | Louisville | Kentucky | 40202 | United States | Details |
| Oregon Health and Science University | RECRUITING | Portland | Oregon | 97239 | United States | Details |
| Primary Children's Hospital | RECRUITING | Salt Lake City | Utah | 84113 | United States | Details |
| Prisma Health Richland Hospital | RECRUITING | Columbia | South Carolina | 29203 | United States | Details |
| Providence Sacred Heart Medical Center and Children's Hospital | RECRUITING | Spokane | Washington | 99204 | United States | Details |
| Riley Hospital for Children | RECRUITING | Indianapolis | Indiana | 46202 | United States | Details |
| Roswell Park Cancer Institute | RECRUITING | Buffalo | New York | 14263 | United States | Details |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital | RECRUITING | New Brunswick | New Jersey | 08903 | United States | Details |
| Saint Christopher's Hospital for Children | RECRUITING | Philadelphia | Pennsylvania | 19134 | United States | Details |
| Saint Joseph's Hospital/Children's Hospital-Tampa | RECRUITING | Tampa | Florida | 33607 | United States | Details |
| Saint Luke's Cancer Institute - Boise | RECRUITING | Boise | Idaho | 83712 | United States | Details |
| Sanford Broadway Medical Center | RECRUITING | Fargo | North Dakota | 58122 | United States | Details |
| Seattle Children's Hospital | RECRUITING | Seattle | Washington | 98105 | United States | Details |
| State University of New York Upstate Medical University | RECRUITING | Syracuse | New York | 13210 | United States | Details |
| The Montreal Children's Hospital of the MUHC | RECRUITING | Montreal | Quebec | H3H 1P3 | Canada | Details |
| The Steven and Alexandra Cohen Children's Medical Center of New York | RECRUITING | New Hyde Park | New York | 11040 | United States | Details |
| University of Alberta Hospital | RECRUITING | Edmonton | Alberta | T6G 2B7 | Canada | Details |
| University of Chicago Comprehensive Cancer Center | RECRUITING | Chicago | Illinois | 60637 | United States | Details |
| University of Florida Health Science Center - Gainesville | RECRUITING | Gainesville | Florida | 32610 | United States | Details |
| University of Illinois | RECRUITING | Chicago | Illinois | 60612 | United States | Details |
| University of Iowa/Holden Comprehensive Cancer Center | RECRUITING | Iowa City | Iowa | 52242 | United States | Details |
| University of Minnesota/Masonic Cancer Center | RECRUITING | Minneapolis | Minnesota | 55455 | United States | Details |
| University of Mississippi Medical Center | RECRUITING | Jackson | Mississippi | 39216 | United States | Details |
| University of Nebraska Medical Center | RECRUITING | Omaha | Nebraska | 68198 | United States | Details |
| University of New Mexico Cancer Center | RECRUITING | Albuquerque | New Mexico | 87106 | United States | Details |
| University of Oklahoma Health Sciences Center | RECRUITING | Oklahoma City | Oklahoma | 73104 | United States | Details |
| University of Texas Health Science Center at San Antonio | RECRUITING | San Antonio | Texas | 78229 | United States | Details |
| University of Wisconsin Carbone Cancer Center - University Hospital | RECRUITING | Madison | Wisconsin | 53792 | United States | Details |
| UT Southwestern/Simmons Cancer Center-Dallas | RECRUITING | Dallas | Texas | 75390 | United States | Details |
| Vanderbilt University/Ingram Cancer Center | RECRUITING | Nashville | Tennessee | 37232 | United States | Details |
| Virginia Commonwealth University/Massey Cancer Center | RECRUITING | Richmond | Virginia | 23298 | United States | Details |
| Wake Forest University Health Sciences | RECRUITING | Winston-Salem | North Carolina | 27157 | United States | Details |
| Walter Reed National Military Medical Center | RECRUITING | Bethesda | Maryland | 20889-5600 | United States | Details |
| Washington University School of Medicine | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| West Virginia University Healthcare | RECRUITING | Morgantown | West Virginia | 26506 | United States | Details |
| Yale University | RECRUITING | New Haven | Connecticut | 06520 | United States | Details |
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