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| NCT ID | NCT04576455 |
| Title | A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (acelERA Breast Cancer) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | ISR | GBR | DEU | BRA | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Northwest Georgia Oncology Centers PC - Marietta | Marietta | Georgia | 30060 | United States | Details | |
| Illinois Cancer Specialists | Niles | Illinois | 60714 | United States | Details | |
| Ashland-Bellefonte Cancer Center | Ashland | Kentucky | 41101-7016 | United States | Details | |
| St. Vincent Frontier Cancer Center | Billings | Montana | 59102 | United States | Details | |
| University Hospitals Seidman Cancer Center | Cleveland | Ohio | 44106 | United States | Details | |
| Northwest Cancer Specialists - Portland (SW Barnes Rd) | Tigard | Oregon | 97223 | United States | Details | |
| Texas Oncology Cancer Center | Austin | Texas | 78731 | United States | Details | |
| Texas Oncology - El Paso | El Paso | Texas | 79902 | United States | Details | |
| Texas Oncology - Houston (Gessner) | Houston | Texas | 77024 | United States | Details | |
| Texas Oncology- Northeast Texas | Tyler | Texas | 75702 | United States | Details | |
| Fundación CENIT para la Investigación en Neurociencias | Buenos Aires | C1125ABD | Argentina | Details | ||
| Instituto Angel Roffo | Ciudad Autonoma Buenos Aires | C1417DTB | Argentina | Details | ||
| Fundación Scherbovsky; General Department | Mendoza | M5500AYB | Argentina | Details | ||
| Hosp Provincial D. Centenarios; Oncology Dept | Rosario | S2002KDS | Argentina | Details | ||
| Organizacion Medica de Investigacion | San Nicolás | C1015ABO | Argentina | Details | ||
| Kinghorn Cancer Centre; St Vincents Hospital | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| Sunshine Hospital | St Albans | Victoria | 3021 | Australia | Details | |
| Pronutrir - suporte nutricional e quimioterapia ltda. | Fortaleza | CE | 60810-180 | Brazil | Details | |
| Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda | Ijui | RS | 98700-000 | Brazil | Details | |
| Santa Casa de Misericordia de Porto Alegre | Porto Alegre | RS | 90020-090 | Brazil | Details | |
| Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda | Sao Paulo | SP | 01317-001 | Brazil | Details | |
| Núcleo de Pesquisa São Camilo; ONCOLOGIA CLINICA / QUIMIOTERAPIA | Sao Paulo | SP | 04014-002 | Brazil | Details | |
| The First Hospital of Jilin University | Changchun City | 130021 | China | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou City | 510663 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Linyishi Cancer Hospital | Linyi City | 276034 | China | Details | ||
| The Third Hospital of Nanchang | Nanchang City | 330009 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai City | 200120 | China | Details | ||
| Tianjin Cancer Hospital | Tianjin | 300060 | China | Details | ||
| Hubei Cancer Hospital | Wuhan | 430079 | China | Details | ||
| First Affiliated Hospital of Medical College of Xi'an Jiaotong University | Xi'an | 710061 | China | Details | ||
| Zhejiang Cancer Hospital | Zhejiang | 310022 | China | Details | ||
| Hämato-Onkologische Schwerpunktpraxis am Klinikum Aschaffenburg | Aschaffenburg | 63739 | Germany | Details | ||
| Frauenarzt-Zentrum Zehlendorf an der Teltower Eiche | Berlin | 14169 | Germany | Details | ||
| Kooperatives Mammazentrum Hamburg Krankenhaus Jerusalem | Hamburg | 20357 | Germany | Details | ||
| St. Vincenz-Krankenhaus Paderborn; Haus 3 Frauenklinik | Paderborn | 33098 | Germany | Details | ||
| Gynäkologie Kompetenzzentrum; Praxis Dr. med. Carsten Hielscher | Stralsund | 18439 | Germany | Details | ||
| Assuta Medical Center- Ashdod; Oncology | Ashdod | 7747629 | Israel | Details | ||
| Hadassah Ein Karem Hospital; Oncology Dept | Jerusalem | 9112000 | Israel | Details | ||
| Meir Medical Center; Oncology | Kfar-Saba | 4428164 | Israel | Details | ||
| Soon Chun Hyang University Cheonan Hospital | Dongnam-gu, Cheonan-si | 31151 | Korea, Republic of | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Gangnam Severance Hospital | Seoul | 06273 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Seoul St Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Bialostockie Centrum Onkologii; Oddzial Onkologii Klinicznej | Bialystok | 15-027 | Poland | Details | ||
| Narodowy Instytut Onkologii Odzia? w Gliwicach; Centrum Diagnostyki i Leczenia Chorób Piersi | Gliwice | 44-102 | Poland | Details | ||
| Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad; Klinika Nowtw.Piersi i Chir.Rekonstr | Warszawa | 02-781 | Poland | Details | ||
| Krasnoyarsk Regional Oncology Dispensary n.a. Krizhanovsky; Chemotherapy | Krasnoyarsk | Krasnodar | 660133 | Russian Federation | Details | |
| Blokhin Cancer Research Center; Combined Treatment | Moskva | Moskovskaja Oblast | 115478 | Russian Federation | Details | |
| Filial #1 Regional Oncology Dispensary of Nizhniy Novgorod | Nizhny Novgorod | Niznij Novgorod | 603081 | Russian Federation | Details | |
| St. Petersburg SHI "City Clinical Oncology Dispensary" | Sankt-peterburg | Sankt Petersburg | 198255 | Russian Federation | Details | |
| Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic | Kazan | Tatarstan | 420029 | Russian Federation | Details | |
| Clinical Oncology Centre # 1; Chemotherapy Dept | Krasnodar | 350040 | Russian Federation | Details | ||
| Multidisciplinary clinic Reaviz | Samara | 443011 | Russian Federation | Details | ||
| Petrov Research Inst. of Oncology | Sankt Petersburg | 197758 | Russian Federation | Details | ||
| Volgograd Regional Clinical Oncology Dispensary | Volgograd | 400138 | Russian Federation | Details | ||
| Regional Clinical Oncology Hospital | Yaroslavl | 150040 | Russian Federation | Details | ||
| National University Hospital; National University Cancer Institute, Singapore (NCIS) | Singapore | 119228 | Singapore | Details | ||
| National Cancer Centre; Medical Oncology | Singapore | 168583 | Singapore | Details | ||
| Iatros International | Bloemfontein | 9301 | South Africa | Details | ||
| Cancercare Langenhoven Drive Oncology Centre | Port Elizabeth | 6045 | South Africa | Details | ||
| Eastleigh Breast Care Centre | Pretoria | 0081 | South Africa | Details | ||
| Changhua Christian Hospital; Dept of Surgery | Changhua | 500 | Taiwan | Details | ||
| National Cheng Kung Uni Hospital; Dept of Hematology and Oncology | Tainan | 704 | Taiwan | Details | ||
| Chi-Mei Medical Centre; Hematology & Oncology | Tainan | 710 | Taiwan | Details | ||
| VETERANS GENERAL HOSPITAL; Department of General Surgery | Taipei | 00112 | Taiwan | Details | ||
| Chang Gung Memorial Hosipital at Linkou | Taoyuan City | 333 | Taiwan | Details | ||
| Chulalongkorn Hospital; Medical Oncology | Bangkok | 10330 | Thailand | Details | ||
| Rajavithi Hospital; Division of Medical Oncology | Bangkok | 10400 | Thailand | Details | ||
| Ramathibodi Hospital; Dept of Med.-Div. of Med. Onc | Bangkok | 10400 | Thailand | Details | ||
| Maharaj Nakorn Chiang Mai Hosp; Surgery/Oncology | Chang Mai | 50200 | Thailand | Details | ||
| Songklanagarind Hospital; Department of Oncology | Songkhla | 90110 | Thailand | Details | ||
| Memorial Ankara Hastanesi | Ankara | 06520 | Turkey | Details | ||
| Ankara City Hospital; Oncology | Ankara | 06800 | Turkey | Details | ||
| Memorial Antalya Hospital | Antalya | 07025 | Turkey | Details | ||
| Dicle University Faculty of Medicine | Diyarbakir | 21280 | Turkey | Details | ||
| Prof. Dr. Cemil Tascioglu City Hospital; Med Onc | Istanbul | 34384 | Turkey | Details | ||
| Kartal Dr Lutfi Kirdar Sehir Hastanesi; Medical Oncology Department | Istanbul | 34865 | Turkey | Details | ||
| Katip Celebi University Ataturk Training and Research Hospital; Oncology | Izmir | 35360 | Turkey | Details | ||
| Medikal Park Samsun | Samsun | 55200 | Turkey | Details | ||
| Zhytomyr Regional Oncology Center | Zhytomyr | KIEV Governorate | 10007 | Ukraine | Details | |
| Kyiv City Clinical Oncological Center | Kyiv | 03115 | Ukraine | Details | ||
| MI Kyiv Regional Council Kyiv Regional Oncological Dispensary; Department of Mammology | Kyiv | 04107 | Ukraine | Details | ||
| RCI Sumy Regional Clinical Oncological Dispensary | Sumy | 40005 | Ukraine | Details | ||
| Princess Alexandra Hospital; Oncology Department | Harlow | CM20 1QX | United Kingdom | Details | ||
| Guys & St Thomas Hospital; Department of Oncology | London | SE1 9RT | United Kingdom | Details | ||
| Nottingham City Hospital; Oncology | Nottingham | NG5 1PB | United Kingdom | Details | ||
| Peterborough City Hospital; Oncology Research Department 018 | Peterborough | PE3 9GZ | United Kingdom | Details |