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| NCT ID | NCT04585750 |
| Title | The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | PMV Pharmaceuticals, Inc |
| Indications | |
| Therapies | |
| Age Groups: | child | adult | senior |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DEU | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Abramson Cancer Center of the University of Pennsylvania | RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Advent Health | NOT_YET_RECRUITING | Orlando | Florida | 32803 | United States | Details |
| Asan Medical Center | RECRUITING | Seoul | Korea, Republic of | Details | ||
| Asklepios Klinik Altona | RECRUITING | Hamburg | Germany | Details | ||
| ASST Grande Ospedale Metropolitano Niguarda | RECRUITING | Milano | Lombardia | Italy | Details | |
| Centre Jean Perrin | RECRUITING | Clermont-Ferrand | Puy-de-Dôme | France | Details | |
| Centre Léon Bérard Centre Régional de Lutte Contre Le Cancer | RECRUITING | Lyon | France | Details | ||
| Chris O'Brien Lifehouse Hospital | RECRUITING | Camperdown | New South Wales | Australia | Details | |
| CHU de Nîmes | RECRUITING | Nîmes | 30900 | France | Details | |
| Dana Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Duke University | RECRUITING | Durham | North Carolina | 27705 | United States | Details |
| EDOG Institut de Cancerologie de l'Ouest | RECRUITING | Saint-Herblain | Loire-Atlantique | France | Details | |
| Flinders Medical Center | RECRUITING | Bedford Park | South Australia | Australia | Details | |
| Florida Cancer Specialists South | RECRUITING | Port Charlotte | Florida | 33980 | United States | Details |
| Fondazione del Piemonte per l'Oncologia (IRCCS) | RECRUITING | Candiolo | Torino | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale Dei Tumori | RECRUITING | Milano | Lombardia | Italy | Details | |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS | RECRUITING | Rome | Lazio | Italy | Details | |
| Freeman Hospital | RECRUITING | Newcastle Upon Tyne | Tyne And Wear | United Kingdom | Details | |
| Hoag Cancer Center | WITHDRAWN | Irvine | California | 92618 | United States | Details |
| Hospital Clinico Universitario de Valencia | RECRUITING | Valencia | Spain | Details | ||
| Hospital Universitario 12 de Octubre | RECRUITING | Madrid | 28041 | Spain | Details | |
| ICANS - Institut de cancérologie Strasbourg Europe | RECRUITING | Strasbourg | Bas-Rhin | France | Details | |
| Indiana University | WITHDRAWN | Indianapolis | Indiana | 46240 | United States | Details |
| Institut Bergonie | RECRUITING | Bordeaux | Gironde | France | Details | |
| Institut Claudius Regaud | RECRUITING | Toulouse | Haute-Garonne | France | Details | |
| Institut Gustave Roussy | RECRUITING | Villejuif | Val-de-Marne | France | Details | |
| Institute Cancer De Lorraine | RECRUITING | Vandœuvre-lès-Nancy | 54519 | France | Details | |
| Instituto de Investigacion Oncologica Vall d'Hebron (VHIO) - EPON | RECRUITING | Barcelona | Spain | Details | ||
| IRCCS - lstituto Nazionale Tumori - Fondazione G. Pascale | RECRUITING | Napoli | 80131 | Italy | Details | |
| Istituti Fisioterapici Ospitalieri - Istituto Nazionale Tumori Regina Elena | RECRUITING | Rome | Lazio | Italy | Details | |
| Istituto Clinico Humanitas | RECRUITING | Rozzano | Lombardia | Italy | Details | |
| Istituto Europeo Di Oncologia | RECRUITING | Milano | Lombardia | Italy | Details | |
| Karmanos Cancer Institute | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Linear Clinical Research | RECRUITING | Nedlands | Western Australia | Australia | Details | |
| Massachusetts General Hospital | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Mater Cancer Care Centre | NOT_YET_RECRUITING | South Brisbane | Queensland | Australia | Details | |
| Medical Oncology Hematology Consultants | RECRUITING | Newark | Delaware | 19713 | United States | Details |
| Medical University of South Carolina | RECRUITING | Charleston | South Carolina | 29425 | United States | Details |
| Memorial Sloan Kettering | RECRUITING | New York | New York | 10065 | United States | Details |
| Monash Medical Centre | RECRUITING | Clayton | Victoria | Australia | Details | |
| National Cancer Center | NOT_YET_RECRUITING | Seoul | Korea, Republic of | Details | ||
| National Cancer Center of Singapore | RECRUITING | Singapore | 168582 | Singapore | Details | |
| National University Hospital | RECRUITING | Kent Ridge | Singapore | Details | ||
| Nationale Centrum für Tumorerkrankungen (NCT) Heidelberg | RECRUITING | Heidelberg | Baden-Württemberg | Germany | Details | |
| New Experimental Therapeutics - NEXT Oncology | RECRUITING | Austin | Texas | 78705 | United States | Details |
| New Experimental Therapeutics of San Antonio - NEXT Oncology | RECRUITING | San Antonio | Texas | 78229 | United States | Details |
| New York University | NOT_YET_RECRUITING | New York | New York | 10016 | United States | Details |
| NEXT Oncology-Hospital Quironsalud Barcelona | RECRUITING | Barcelona | Spain | Details | ||
| Oregon Health & Science University (OHSU) | RECRUITING | Portland | Oregon | 97210 | United States | Details |
| Robert H. Lurie Comprehensive Cancer Center of Northwestern University | NOT_YET_RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| Rocky Mountain Cancer Center | RECRUITING | Denver | Colorado | 80218 | United States | Details |
| Samsung Medical Center | NOT_YET_RECRUITING | Seoul | Korea, Republic of | Details | ||
| Sarah Cannon Research Institute | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Sarah Cannon Research Institute UK | RECRUITING | London | Middlesex | United Kingdom | Details | |
| Seoul University Hospital | RECRUITING | Seoul | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University | NOT_YET_RECRUITING | Seoul | Korea, Republic of | Details | ||
| START MADRID_Hospital Universitario Fundacion Jimenez Diaz | RECRUITING | Madrid | Spain | Details | ||
| START MADRID_Hospital Universitario HM Sanchinarro - CIOCC | RECRUITING | Madrid | Spain | Details | ||
| Swedish Medical Center | NOT_YET_RECRUITING | Seattle | Washington | 98122- | United States | Details |
| The Cleveland Clinic Taussig Cancer Center | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| The University of Texas MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| UCLA Jonsson Comprehensive Cancer Center | NOT_YET_RECRUITING | Los Angeles | California | 90024 | United States | Details |
| University of California Irvine Chao Family Comprehensive Cancer Center | NOT_YET_RECRUITING | Irvine | California | 92868 | United States | Details |
| University of Miami - Sylvester Comprehensive Cancer Center | RECRUITING | Miami | Florida | 33136 | United States | Details |
| University of Oklahoma | RECRUITING | Oklahoma City | Oklahoma | 73104 | United States | Details |
| University of Pittsburgh Medical Center | NOT_YET_RECRUITING | Pittsburgh | Pennsylvania | 15213 | United States | Details |
| University of San Francisco | WITHDRAWN | San Francisco | California | 94143 | United States | Details |
| University of Washington, Fred Hutchinson Cancer Center | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| University of Wisconsin Carbone Cancer Center | RECRUITING | Madison | Wisconsin | 53705 | United States | Details |
| Universitätsklinikum Augsburg | RECRUITING | Augsburg | Bayern | Germany | Details | |
| Universitätsklinikum Essen | RECRUITING | Essen | Nordrhein-Westfalen | Germany | Details | |
| Universitätsklinikum Frankfurt | RECRUITING | Frankfurt | Hessen | Germany | Details | |
| USC Norris Comprehensive Cancer Center | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| UT Southwest Simmons Cancer Center | NOT_YET_RECRUITING | Dallas | Texas | 75390 | United States | Details |
| UTSW - Moody Outpatient Center - Parkland Health | NOT_YET_RECRUITING | Dallas | Texas | 75235 | United States | Details |
| Vanderbilt University Medical Center - Ingram Cancer Center | WITHDRAWN | Nashville | Tennessee | 37232 | United States | Details |
| Virginia Cancer Specialists | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| WellSpan York Cancer Center | NOT_YET_RECRUITING | York | Pennsylvania | 17403 | United States | Details |
| Yale Cancer Center | RECRUITING | New Haven | Connecticut | 06519 | United States | Details |
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