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NCT ID | NCT04666038 |
Title | Study of LOXO-305 Versus Investigator's Choice (IdelaR or BR) in Patients With CLL or SLL |
Acronym | BRUIN CLL-321 |
Recruitment | Active, not recruiting |
Gender | both |
Phase | Phase III |
Variant Requirements | No |
Sponsors | Loxo Oncology, Inc. |
Indications | |
Therapies | |
Age Groups: | senior | adult |
Covered Countries | USA | TUR | POL | ITA | ISR | IRL | HUN | HRV | GBR | FRA | ESP | DEU | CZE | CHE | CAN | BEL | AUT | AUS |
Facility | Status | City | State | Zip | Country | Details |
---|---|---|---|---|---|---|
Southern Cancer Center, P.C. | Daphne | Alabama | 36526 | United States | Details | |
Mitchell Cancer Institute -University of South Alabama | Mobile | Alabama | 36604 | United States | Details | |
Palo Verde Hematology Oncology | Glendale | Arizona | 85304 | United States | Details | |
Arizona Oncology Associates, P.C. - HOPE | Tucson | Arizona | 85711 | United States | Details | |
Orange Coast Memorial Medical Center | Fountain Valley | California | 92708 | United States | Details | |
California Research Institute | Los Angeles | California | 90027 | United States | Details | |
Rocky Mountain Cancer Center | Aurora | Colorado | 80012 | United States | Details | |
Medical Oncology Hematology Consultants, PA | Newark | Delaware | 19713 | United States | Details | |
Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | United States | Details | |
Cancer Specialists of North Florida -St Augustine | Jacksonville | Florida | 32256 | United States | Details | |
Oncology-Hematology Associates of West Broward | Tamarac | Florida | 33321 | United States | Details | |
WellStar Health System | Marietta | Georgia | 30060 | United States | Details | |
Rush University Medical Center | Chicago | Illinois | 60612 | United States | Details | |
Illinois Cancer Specialists-Niles | Niles | Illinois | 60714 | United States | Details | |
Community Health Network | Indianapolis | Indiana | 46250 | United States | Details | |
Arnett Cancer Center | Lafayette | Indiana | 47904 | United States | Details | |
University of Kentucky Markey Cancer Center | Lexington | Kentucky | 40563 | United States | Details | |
Norton Cancer Institute | Louisville | Kentucky | 40207 | United States | Details | |
Mercy Health-Paducah Medical Oncology and Hematology | Paducah | Kentucky | 42003 | United States | Details | |
Cancer Center Office of Clinical Research | New Orleans | Louisiana | 70112 | United States | Details | |
Greenebaum Comprehensive Cancer Center | Baltimore | Maryland | 21201 | United States | Details | |
Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | United States | Details | |
Ascension St. John Hospital | Grosse Pointe Woods | Michigan | 48236 | United States | Details | |
Minnesota Oncology/Hematology PA | Saint Paul | Minnesota | 55102 | United States | Details | |
St. Vincent Frontier Cancer Center | Billings | Montana | 59102 | United States | Details | |
Nebraska Hematology-Oncology | Lincoln | Nebraska | 68506 | United States | Details | |
New Jersey Center for Cancer Research | Brick | New Jersey | 08724 | United States | Details | |
Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | United States | Details | |
University of Rochester | Rochester | New York | 14642 | United States | Details | |
Clinical Research Alliance, Inc. | Westbury | New York | 11590 | United States | Details | |
Oncology Hematology Care Inc | Cincinnati | Ohio | 45236 | United States | Details | |
Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | United States | Details | |
Carolina Blood and Cancer Care Associates | Rock Hill | South Carolina | 29732 | United States | Details | |
Texas Oncology - Amarillo | Amarillo | Texas | 79106 | United States | Details | |
Texas Oncology Cancer Center | Austin | Texas | 78705 | United States | Details | |
Texas Oncology - Medical City Dallas | Dallas | Texas | 75230 | United States | Details | |
Texas Oncology - Dallas Presbyterian Hospital | Dallas | Texas | 75231 | United States | Details | |
Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | United States | Details | |
Texas Oncology Fort Worth | Fort Worth | Texas | 76104 | United States | Details | |
The Center for Cancer and Blood Disorders | Fort Worth | Texas | 76104 | United States | Details | |
Texas Oncology - McAllen | McAllen | Texas | 78503 | United States | Details | |
Texas Oncology - San Antonio Medical Center | San Antonio | Texas | 78240 | United States | Details | |
Virginia Cancer Specialists, PC | Gainesville | Virginia | 20155 | United States | Details | |
Oncology and Hematology Associates of Southwest Virginia Inc | Roanoke | Virginia | 24014 | United States | Details | |
Northwest Medical Specialties, PLLC | Tacoma | Washington | 98405 | United States | Details | |
University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53705 | United States | Details | |
Canberra Hospital | Garran | Australian Capital Territory | 2605 | Australia | Details | |
St Vincent's Hospital | Darlinghurst | New South Wales | 2010 | Australia | Details | |
The St. George Hospital | Kogarah | New South Wales | 2217 | Australia | Details | |
Ingham Institute of Medical Research | Liverpool | New South Wales | NSW2170 | Australia | Details | |
Westmead Hospital | Wentworthville | New South Wales | 2145 | Australia | Details | |
The Alfred Hospital | Melbourne | Victoria | 3004 | Australia | Details | |
Royal Perth Hospital | Perth | Western Australia | 6000 | Australia | Details | |
Ordensklinikum Linz GmbH Elisabethinen | Linz | Oberösterreich | 4020 | Austria | Details | |
Uniklinikum Salzburg | Salzburg | Osterreich | 5020 | Austria | Details | |
Medizinische Universität Wien | Wien | 1090 | Austria | Details | ||
CHR Verviers-Onco | Verviers | Liege | 4800 | Belgium | Details | |
VITAZ | Sint-Niklaas | Oost-Vlaanderen | B-9100 | Belgium | Details | |
AZ Delta | Roeselare | West Flanders | 8800 | Belgium | Details | |
Universitair Ziekenhuis Gent | Gent | 9000 | Belgium | Details | ||
Groupe Jolimont | Haine-Saint-Paul | 7100 | Belgium | Details | ||
AZ St-Elisabeth | Herentals | 2200 | Belgium | Details | ||
Clinique Saint Pierre Ottignies | Ottignies | 1340 | Belgium | Details | ||
Cancer Care Manitoba | Winnipeg | Manitoba | R3E 0V9 | Canada | Details | |
Queen Elizabeth II Health Sciences Center | Halifax | Nova Scotia | B3H 1V7 | Canada | Details | |
Southlake Regional Health Centre | Newmarket | Ontario | L3Y 2P9 | Canada | Details | |
Princess Margaret Hospital (Ontario) | Toronto | Ontario | M5G 1Z5 | Canada | Details | |
Peking University First Hospital | Beijing | Beijing | 100034 | China | Details | |
Peking University Third Hospital | Beijing | Beijing | 100191 | China | Details | |
Xuanwu Hospital Capital Medical University | Xicheng District | Beijing | 100053 | China | Details | |
Gansu Province Cancer Hospital | Lanzhou | Gansu | 730050 | China | Details | |
Sun Yat-sen University Cancer Center | Guangzhou | Guangdong | 510000 | China | Details | |
Southern Medical University Nanfang Hospital | Guangzhou | Guangdong | 510515 | China | Details | |
Hainan Province People's Hospital | Haikou | Hainan | 570100 | China | Details | |
Henan Cancer Hospital | Zhengzhou | Henan | 450008 | China | Details | |
Hunan Cancer Hospital | Changsha | Hunan | 410013 | China | Details | |
The Affiliated Hospital of Xuzhou Medical College | Xuzhou | Jiangsu | 221006 | China | Details | |
The First Affiliated Hospital of Nanchang University | Nanchang | Jiangxi | 330006 | China | Details | |
The Second Affiliated Hospital of Nanchang University | Nanchang | Jiangxi | 330006 | China | Details | |
Tianjin Medical University Cancer Institute and Hospital | Tianjin | Tianjin | China | Details | ||
Affiliated Tumor Hospital of Xinjiang Medical University | Ürümqi | Xinjiang | 830002 | China | Details | |
Zhejiang Cancer Hospital | Hangzhou | Zhejiang | 310022 | China | Details | |
Zhejiang Provincial Taizhou Hospital | Linhai | Zhejiang | 317000 | China | Details | |
Beijing Hospital | Beijing | 100730 | China | Details | ||
Shanghai Jiaotong University School of Medicine Ruijin Hospital | Shanghai | 200025 | China | Details | ||
Fudan University Shanghai Cancer Center | Shanghai | 200032 | China | Details | ||
Blood Institute of the Chinese Academy of Medical science | Tianjin | 300020 | China | Details | ||
University Hospital Split | Split | 21000 | Croatia | Details | ||
Division of Hematology, Dept. of Internal Medicine, University Hospital Centre Zagreb | Zagreb | Croatia | Details | |||
Fakultni nemocnice Brno | Brno | 62500 | Czechia | Details | ||
Fakultni nemocnice Hradec Kralove | Hradec Kralove | 500 05 | Czechia | Details | ||
Vseobecna fakultni nemocnice v Praze | Praha 2 | 12808 | Czechia | Details | ||
CHU De Grenoble Hopital Albert Michallon | Grenoble | Cedex 09 | 38043 | France | Details | |
Hospital AVICENNE | Bobigny | Cedex | 93 009 | France | Details | |
Centre Hospitalier Lyon Sud | Pierre Benite | Cedex | 69495 | France | Details | |
CHD Vendee | La Roche-sur-Yon | La Roche Sur Yon | 85000 | France | Details | |
Chu Nimes/Institut De Cancerologie Du Gard | Nîmes | Nimes | 30900 | France | Details | |
Centre de Lutte Contre le Cancer - Centre Henri Becquerel Normandie Rouen | Rouen | Seine-Maritime | 76038 | France | Details | |
CHRU De Tours | Tours | Tours Cedex 9 | 37044 | France | Details | |
Centre Hospitalier de la Côte Basque | Bayonne | 64109 | France | Details | ||
Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest | Bordeaux | 33076 | France | Details | ||
CHRU de Brest - Hôpital Morvan | Brest cedex | 29609 | France | Details | ||
Centre Hospitalier du Mans | Le Mans | 72000 | France | Details | ||
Hopital Saint Vincent De Paul | Lille cedex | 59020 | France | Details | ||
Ch Perpignan | Perpignan | 66046 | France | Details | ||
Pole Regionalde Cancérologie(CHU de Poitiers) | Politiers | 86021 | France | Details | ||
Universitätsklinikum Heidelberg | Heidelberg | Baden-Württemberg | 69120 | Germany | Details | |
Universitätsklinikum Ulm | Ulm | Baden-Württemberg | 89081 | Germany | Details | |
Uniklinik Köln | Kerpener | Köln | 50937 | Germany | Details | |
Universitätsmedizin Mainz III. Medizinische Klinik und Poliklinik | Langenbeckstraße 1 | Mainz | D- 55131 | Germany | Details | |
München Klinik Schwabing | Koelner Platz 1 | München | 80804 | Germany | Details | |
Universitätsklinikum Schleswig-Holstein | Kiel | Schleswig-Holstein | 24105 | Germany | Details | |
Lübecker Onkologische Schwerpunktpraxis | Lübeck | Schleswig-Holstein | 23562 | Germany | Details | |
Charité Campus Virchow-Klinikum | Berlin | 12203 | Germany | Details | ||
Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet | Budapest | 1097 | Hungary | Details | ||
Debreceni Egyetem Klinikai Kozpont | Debrecen | 4032 | Hungary | Details | ||
SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz | Nyiregyhaza | 4400 | Hungary | Details | ||
University of Pecs 1st. Internalmedicin Clinic Dept | Pecs | 7624 | Hungary | Details | ||
Mater Misericordiae Hospital | Dublin 7 | Ireland | Details | |||
St James's Hosptial | Dublin 8 | D08 NHY1 | Ireland | Details | ||
Beaumont Hospital, Dublin | Dublin | DUBLIN 9 | Ireland | Details | ||
Rabin Medical Center | Petah Tikva | HaMerkaz | Israel | Details | ||
Soroka Medical Center | Beer Sheva | 8457108 | Israel | Details | ||
Laniado Medical Center | Netanya | 4244916 | Israel | Details | ||
Tel Aviv Sourasky Medical Center | Tel Aviv | 6423906 | Israel | Details | ||
Carmel Hospital | Haifa | Ḥeifā | 3436212 | Israel | Details | |
Irccs Istituto Tumori Giovanni Paolo Ii | Viale Orazio Flacco | Bari | 70124 | Italy | Details | |
ASST-Monza -U.O Ematologia Adulti | Monza (MB) -Settore E | Piano 2 | 20900 | Italy | Details | |
Azienda Ospedaliero Universitaria Pisana | Pisa | PI | 56126 | Italy | Details | |
Irccs Crob | Rionero In Vulture | Potenza | 85028 | Italy | Details | |
AULSS8 Berica-Ospedale S.Bortolo | Vicenza | Veneto | 36100 | Italy | Details | |
Azienda Ospedaliera Nazionale Santi Antonio e Biagio e Cesare Arrigo | Alessandria | 15100 | Italy | Details | ||
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII | Bergamo | 24127 | Italy | Details | ||
ASST Spedali Civili - Università degli Studi | Brescia | 25123 | Italy | Details | ||
A.O.U. Policlinico G.Rodolico - S. Marco | Catania | 95123 | Italy | Details | ||
Azienda Ospedaliera Pugliese Ciaccio | Catanzaro | 88100 | Italy | Details | ||
Azienda Ospedaliera Universitaria Careggi | Firenze | 50134 | Italy | Details | ||
IRCCS Ospedale Policlinico San Martino | Genova | 16132 | Italy | Details | ||
Ospedale Papardo | Messina | 98158 | Italy | Details | ||
IRCCS Ospedale San Raffaele | Milano | 20132 | Italy | Details | ||
ASST Grande Ospedale Metropolitano Niguarda Comitato Etico Milano Area C | Milano | 20162 | Italy | Details | ||
A.O.U. di Modena | Modena | 41124 | Italy | Details | ||
Fondazione IRCCS Policlinico San Matteo | Pavia | 27100 | Italy | Details | ||
Istituto di Ematologia-C.R.E.O. (Centro di Ricerche Emato-Oncologich) | Perugia | 06132 | Italy | Details | ||
Ospedale Santa Maria delle Croci | Ravenna | 48020 | Italy | Details | ||
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore | Roma | 00168 | Italy | Details | ||
Azienda Ospedaliera Santa Maria Terni | Terni | 05100 | Italy | Details | ||
A.O.U. Citta' della Salute e della Scienza di Torino | Torino | 10126 | Italy | Details | ||
Az. Osp. "Card G Panico" | Tricase | 4 - 73039 | Italy | Details | ||
Azienda Sanitaria Universitaria Giuliano Isontina | Trieste | 34125 | Italy | Details | ||
Ospedale Policlinico Giambattista Rossi, Borgo Roma | Verona | 37134 | Italy | Details | ||
Nagoya Medical Center | Nagoya | Aichi | 460-0001 | Japan | Details | |
Aichi Cancer Center Hospital | Nagoya | Aichi | 464-8681 | Japan | Details | |
Nagoya City University Hospital | Nagoya | Aichi | 467-8602 | Japan | Details | |
Ogaki Municipal Hospital | Ogaki-shi | Gifu | 503-8502 | Japan | Details | |
Hokkaido University Hospital | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
Kobe City Medical Center General Hospital | Kobe | Hyogo | 650-0047 | Japan | Details | |
Tokai University Hospital- Isehara Campus | Isehara | Kanagawa | 259-1143 | Japan | Details | |
Kochi Medical School Hospital | Nankoku | Kochi | 783-8505 | Japan | Details | |
NHO Sendai Medical Center | Sendai-shi | Miyagi-Ken | 983-8520 | Japan | Details | |
Tohoku University Hospital | Sendai-shi | Miyagi | 980-8574 | Japan | Details | |
Kindai University Hospital | Osaka Sayama-shi | Osaka | 589 8511 | Japan | Details | |
Saitama Medical Center | Kawagoe | Saitama | 350-8550 | Japan | Details | |
Japanese Foundation for Cancer Research | Koto | Tokyo | 135-8550 | Japan | Details | |
NTT Medical Center Tokyo | Shinagawa-Ku | Tokyo | 141-8625 | Japan | Details | |
JCHO Kyushu Hospital | Fukoka-ken | 806 8501 | Japan | Details | ||
Kumamoto University Hospital | Kumamoto | 860-8556 | Japan | Details | ||
Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
Osaka University Hospital | Osaka | 565-0871 | Japan | Details | ||
Gachon University Gil Hospital | Namdong-gu | Incheon-gwangyeoksi [Incheon] | 21565 | Korea, Republic of | Details | |
Pusan National University Hospital | Busan | Pusan-Kwangyǒkshi | 49241 | Korea, Republic of | Details | |
Seoul National University Hospital | Seoul | Seoul, Korea | 03080 | Korea, Republic of | Details | |
Severance Hospital, Yonsei University Health System | Seoul | Seoul-teukbyeolsi [Seoul] | 03722 | Korea, Republic of | Details | |
The Catholic University of Korea-Seoul St. Mary's Hospital | Seocho-Gu | Seoul | 06591 | Korea, Republic of | Details | |
Inje Univ Busan Paik Hospital | Busan | 47392 | Korea, Republic of | Details | ||
Wojewodzki Szpital Specjalistyczny | Iwaszkiewicza 5 | Legnica | 59-220 | Poland | Details | |
Centrum Onkologii Ziemi Lubelskiej | Lublin | Lubelskie | 20-081 | Poland | Details | |
Uniwersyteckie Centrum Kliniczne | Gdansk | Pomorskie | 80-214 | Poland | Details | |
Szpitale Pomorskie Sp. z o. o. | Gdynia | Pomorskie | 81-519 | Poland | Details | |
Szpital Specjalistyczny w Brzozowie Podkarpacki Ośrodek Onkologiczny im.ks.B.Markiewicza | Brzozów | 36-200 | Poland | Details | ||
Szpital Uniwersytecki nr 2 im. dr Jana Biziela w BydgoszczyKlinika Hematologii | Bydgoszcz | 85-168 | Poland | Details | ||
Pratia Onkologia Katowice | Katowice | 40519 | Poland | Details | ||
Pratia MCM Krakow | Krakow | 30-510 | Poland | Details | ||
Oddzial Hematologiczny, Specjalistyczny Szpital im. dra Sokołowskiego w Wałbrzychu | Walbrzych | 58-309 | Poland | Details | ||
Instytut Hematologii i Transfuzjologii | Warszawa | 02-776 | Poland | Details | ||
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
Uniwersytecki Szpital Kliniczny Klinika | Wrocław | 50-367 | Poland | Details | ||
Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii | Łódź | 93510 | Poland | Details | ||
Budgetary Healthcare Institution of Omsk Region "Clinical Oncology Dispensary" | Omsk | Omskaya Oblast' | 644013 | Russian Federation | Details | |
Federal State Budgetary Institution "Russian Scientific and Research Institute of Hematology and Transfusiology of Federal Medico-Biological Agency | Saint Petersburg | 191024 | Russian Federation | Details | ||
Academician I.P. Pavlov First St-Petersburg State Medical University | Saint Petersburg | 197022 | Russian Federation | Details | ||
Oncology Dispensary #2 of Krasnodar Region | Sochi | 354057 | Russian Federation | Details | ||
Gleneagles Medical Centre | Singapore | Central Singapore | 258499 | Singapore | Details | |
Hospital Duran I Reynals | Hospitalet De Llobregat | Barcelona | 08908 | Spain | Details | |
Hospital Universitario de Toledo | Toledo | Castilla La Mancha | 45004 | Spain | Details | |
Complejo Hospitalario Universitario de Santiago de Compostel | Santiago de Compostela | La Coruna | 15706 | Spain | Details | |
Hospital Universitario Ramon y Cajal | Madrid | Madrid, Comunidad De | 28034 | Spain | Details | |
Hospital Universitario Quironsalud Madrid | Pozuelo De Alarcón | Madrid | 28223 | Spain | Details | |
Hospital General Universitario Gregorio Marañón | Madrid | Planta Baja | 28007 | Spain | Details | |
Hospital General de Albacete | Albacete | 02006 | Spain | Details | ||
Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
Hospital Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
Hospital San Pedro de Alcántara | Caceres | 10003 | Spain | Details | ||
Hospital Universitario Infanta Leonor-INTERNAL MED | Madrid | 28031 | Spain | Details | ||
Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
Hospital Universitario Marques De Valdecilla | Santander | 39008 | Spain | Details | ||
Hospital Universitario Virgen del Rocío | Sevilla | 41013 | Spain | Details | ||
Hospital Universitario de Alava | Vitoria | 01005 | Spain | Details | ||
Clinica di Ematologia IOSI, Ospedale Bellinzona e Valli, Ente Ospedaliero Cantonale | Bellinzona | Svizzera | 6500 | Switzerland | Details | |
China Medical University Hospital | Taichung City | Taichung | 40447 | Taiwan | Details | |
Tri-Service General Hospital | Taipei City | Taipei | 114 | Taiwan | Details | |
Taipei Veterans General Hospital | Taipei City | 112201 | Taiwan | Details | ||
Chang Gung Memorial Hospital - Linkou | Taoyuan, (r.o.c.) | 33342 | Taiwan | Details | ||
Ankara University Medicine Hospital | Mamak | Ankara | Turkey | Details | ||
Istanbul University Istanbul Medicine Faculty | Faith | Istanbul | Turkey | Details | ||
Erciyes University Faculty of Medicine | Kayseri | Melikgazi | 38039 | Turkey | Details | |
Gazi University Faculty of Medicine | Ankara | Yenimahalle | 06560 | Turkey | Details | |
Ege University Medical Faculty | Izmir | 35100 | Turkey | Details | ||
Dokuz Eylul University Faculty of Medicine | Izmir | 35330 | Turkey | Details | ||
Aberdeen Royal Infirmary | Aberdeen | Aberdeen City | AB25 2ZN | United Kingdom | Details | |
The Royal Cornwall Hospital | Truro | Cornwall | TR1 3LJ | United Kingdom | Details | |
Derriford Hospital | Plymouth | Devon | PL6 8DH | United Kingdom | Details | |
Castle Hill Hospital | Cottingham | East Yorkshire | HU16 5JQ | United Kingdom | Details | |
University College London Hospitals | London | Greater London | WC1E 6HX | United Kingdom | Details | |
Norfolk and Norwich Hospital | Norwich | Norfolk | NR4 7UY | United Kingdom | Details | |
Singleton Hospital | Swansea | Sa2 8qa | United Kingdom | Details | ||
Western General Hospital | Edinburgh | Scotland | EH4 2XU | United Kingdom | Details | |
Royal Marsden Hospital | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
St Johns Hospital at Howden | Livingston | West Lothian | EH54 6PP | United Kingdom | Details | |
St James's University Hospital | Leeds | LS9 7TF | United Kingdom | Details | ||
Milton Keynes University Hospital | Milton Keynes | MK6 5LD | United Kingdom | Details | ||
GenesisCare Cambridge | Newmarket | CB8 7XN | United Kingdom | Details |