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| NCT ID | NCT04674683 |
| Title | Study Comparing Investigational Drug HBI-8000 Combined With Nivolumab vs. Nivolumab in Patients With Advanced Melanoma |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | HUYABIO International, LLC. |
| Indications | |
| Therapies | |
| Age Groups: | child | adult | senior |
| Covered Countries | USA | NZL | ITA | GBR | FRA | ESP | DEU | CZE | BRA | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | United States | Details | |
| UC San Diego Moores Cancer Center | La Jolla | California | 92037 | United States | Details | |
| Innovative Clinical Research Institute (ICRI) | Pasadena | California | 91105 | United States | Details | |
| Emad Ibrahim, MD, INC | Redlands | California | 92373 | United States | Details | |
| Kaiser Permanente Oncology Research | Riverside | California | 92505 | United States | Details | |
| California Cancer Associates for Research and Excellence, Inc. (cCARE) | San Marcos | California | 92069 | United States | Details | |
| Boca Raton Regional Hospital, Lynn Cancer Institute | Boca Raton | Florida | 33486 | United States | Details | |
| Memorial Regional Hospital | Hollywood | Florida | 33021 | United States | Details | |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | United States | Details | |
| Orlando Health | Orlando | Florida | 32806 | United States | Details | |
| Ascension Sacred Heart Medical Oncology | Pensacola | Florida | 32504 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Goshen Center for Cancer Care | Goshen | Indiana | 46526 | United States | Details | |
| St. Elizabeth Healthcare | Edgewood | Kentucky | 41017 | United States | Details | |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | United States | Details | |
| Frederick Memorial Healthcare System | Frederick | Maryland | 21701 | United States | Details | |
| St Louis Cancer Care | Bridgeton | Missouri | 63044 | United States | Details | |
| AMR Kansas City | Kansas City | Missouri | 64114 | United States | Details | |
| Medisearch Clinical Trials | Saint Joseph | Missouri | 64506 | United States | Details | |
| St. Vincent - Frontier Cancer Center | Billings | Montana | 59102 | United States | Details | |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | United States | Details | |
| Southeastern Medical Oncology Center | Goldsboro | North Carolina | 27534 | United States | Details | |
| Gabrail Cancer Center Research | Canton | Ohio | 44718 | United States | Details | |
| Toledo Clinic Cancer Center | Toledo | Ohio | 43623 | United States | Details | |
| Thomas Jefferson University Medical Oncology Clinic | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| AnMed Health | Anderson | South Carolina | 29621 | United States | Details | |
| Carolina Blood and Cancer Care Associates | Lancaster | South Carolina | 29720 | United States | Details | |
| Renovatio Clinical | The Woodlands | Texas | 77380 | United States | Details | |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | United States | Details | |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | United States | Details | |
| Froedtert Hospital, Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| Sydney Adventist Hospital | Wahroonga | New South Wales | Australia | Details | ||
| University of the Sunshine Coast | Buderim | Queensland | 4556 | Australia | Details | |
| Icon Cancer Centre Wesley | South Brisbane | Queensland | Australia | Details | ||
| Ballarat Health Services | Ballarat | Victoria | Australia | Details | ||
| Goulburn Valley Health | Shepparton | Victoria | Australia | Details | ||
| Royal Brisband and Women's Hospital | Brisbane | Australia | Details | |||
| Liverpool Hospital | Liverpool | Australia | Details | |||
| Affinity Clinical Research | Nedlands | Australia | Details | |||
| Tweed Hospital | Tweed Heads | Australia | Details | |||
| Calvary Mater Newcastle | Waratah | Australia | Details | |||
| Medical University of Graz Department of Dermatology and Venerology | Graz | 8036 | Austria | Details | ||
| Univ.-Lkinik für Dermatologie, Venerologie und Allergologie | Innsbruck | 6020 | Austria | Details | ||
| AZ Klina | Brasschaat | 2930 | Belgium | Details | ||
| Cliniques Universitaires | Brussels | 1200 | Belgium | Details | ||
| AZ Maria Middelares | Ghent | 9000 | Belgium | Details | ||
| Jessa Ziekenhuis | Hasselt | 3500 | Belgium | Details | ||
| Hospital de la Citadelle | Liège | 4000 | Belgium | Details | ||
| Clinique Saint-Pierre | Ottignies | 1340 | Belgium | Details | ||
| Ensino e Terapia de Inovação Clίnica AMO-ETICA | Salvador | Bahia | 41950-610 | Brazil | Details | |
| Hospital Erasto Gaertner - Liga Paranaense de Combate ao Câncer, | Curitiba | Paraná | 81520-060 | Brazil | Details | |
| Hospital do Câncer de Londrina | Londrina | Paraná | 86015-520 | Brazil | Details | |
| Hospital São Vicente de Paulo | Centro | Rio Grande Do Sul | 99010-080 | Brazil | Details | |
| Hospital Bruno Born | Lajeado | Rio Grande Do Sul | 95900-010 | Brazil | Details | |
| Centro Gaúcho Integrado de Oncologia, Hematologia | Porto Alegre | Rio Grande Do Sul | 90850-170 | Brazil | Details | |
| Hospital de Clίnίcas de Porto Alegre | Santa Cruz Do Sul | Rio Grande Do Sul | 96810-110 | Brazil | Details | |
| Oncosite-Centro de Pesquisa Clίnica em Oncologia | São Cristóvão | Rio Grande Do Sul | 98700-000 | Brazil | Details | |
| Hopital de Câncer de Barretos-Fundação Pio XII | Barretos | Sao Paulo | 14784-400 | Brazil | Details | |
| CEPHO-Centro de Estudos e Pesquisas de Hematologia e Oncologia | Santo André | São Paulo, | 09060-650 | Brazil | Details | |
| Fundação Doutor Amaral Carvalho | Jaú | São Paulo | 17210-080 | Brazil | Details | |
| Fundação Faculdade Regional de Medicina de São José do Rio Preto | São José Do Rio Preto | São Paulo | 15090-000 | Brazil | Details | |
| Instituto do Cancer do Estado de São Paulo - "Octavio Frias de Oliveira"-ICESP | São Paulo | 01246-000 | Brazil | Details | ||
| Fakultni nemocnice Olomoue | Olomouc | 77900 | Czechia | Details | ||
| Fakultni nemocnice Ostrava Kozni oddeleni | Ostrava-Poruba | 70852 | Czechia | Details | ||
| Fakultni nemocnice Kralovske Vinohrady | Prague | 10034 | Czechia | Details | ||
| CHU de Besançon - Hôpital Jean MINJOZ | Besançon | France | Details | |||
| Hôpital Ambroise Paré | Boulogne-Billancourt | France | Details | |||
| CHU de Dijon, Service de dermatologie | Dijon | France | Details | |||
| CHU Grenoble Alpes | La Tronche | France | Details | |||
| CHRU Lille - Hôpital Claude Huriez, Clinique de Dermatologie | Lille | France | Details | |||
| Hôpital La Timone | Marseille | 13385 Cedex 05 | France | Details | ||
| Hôpital Saint-Louis | Paris | France | Details | |||
| Centre Hospitalier Lyon Sud | Pierre-Bénite | France | Details | |||
| CHU de Rouen-Hôpital | Rouen | 76031 | France | Details | ||
| Institut Gustave Roussy, Service de Dermatologie | Villejuif | France | Details | |||
| Charite Universitaetsmedizin Berlin - Campus Charite Mitte | Berlin | 10117 | Germany | Details | ||
| Vivantes Klinikum Spandau, Dermatologie und Allergologie | Berlin | 13585 | Germany | Details | ||
| Universitaetsklinikum Carl Gustav Carus TU Dresden, Klinik und Poliklinik f. Dermatologie | Dresden, | 01307 | Germany | Details | ||
| Helios Klinikum Erfurt, Dermatologie und Allergologie | Erfurt | 99089 | Germany | Details | ||
| Universitatsklinikum Essen Klinik fur Dermatologie Studienambulanz | Essen | Germany | Details | |||
| Universitaetsklinikum Freiburg, Klinik fuer Dermatologie und Venerologie | Freiburg | 79104 | Germany | Details | ||
| Universitaetsklinikum Heidelberg, NCT-Dermatoonkologie | Heidelberg | 69120 | Germany | Details | ||
| Universitaetsklinikum Koeln, Dermatologie und Venerologie, | Koeln | 50937 | Germany | Details | ||
| Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie | Leipzig | 04103 | Germany | Details | ||
| Universitaetsklinikum Schleswig Holstein - Campus Luebeck | Luebeck | 23538 | Germany | Details | ||
| Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz, Hautklinik | Mainz | 55131 | Germany | Details | ||
| Universitaetsklinikum Mannheim, Klinik f. Dermatologie, Venerologie, Allergologle, | Mannheim | 68167 | Germany | Details | ||
| Studienzentrum Dermao-Onkologie, Universitaetsklinikum Tuebingen | Tuebingen | 72076 | Germany | Details | ||
| Fondazione IRCCS CA'Granda Ospedale Maggiore Policlinico-Oncologia Medica | Milan | Milano | 20122 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milan | Milano | 20133 | Italy | Details | |
| IRCCS Giovanni Paolo II Oncologia Medica | Bari | 70124 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi IRCCS | Bologna | 40138 | Italy | Details | ||
| Humanitas Istituto Clinico Catanese, U.O. Oncologia Medica | Misterbianco | 95045 | Italy | Details | ||
| Istituto Nazionale Tumori Fondazione G. Pascale, Oncologia Medica e Terapia Innovativa | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone - U.O. Oncologia Medica | Palermo | 90127 | Italy | Details | ||
| A.O.S. Maria della Misericordia, Oncologia Medica | Perugia | 06132 | Italy | Details | ||
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Roma | 00168 | Italy | Details | ||
| A.O.U Senese Policlinico Santa Maria alle Scotte-UOC Immunoterapia Oncologica | Siena | 53100 | Italy | Details | ||
| Policlinico G.B. Rossi-Borgo Roma-Centro Ricerche Cliniche di Verona | Verona | 37134 | Italy | Details | ||
| Shinshu University Hospital | Matsumoto | Nagano | 390-8621 | Japan | Details | |
| National Hospital Organization Osaka National Hospital | Chuo Ku | Osaka | 540-0006 | Japan | Details | |
| Shizuoka Cancer Center | Nagaizumi-cho | Sunto-gun | 411-8777 | Japan | Details | |
| The Cancer Institute Hospital of JFCR | Koto-Ku | Tokho | 135-8550 | Japan | Details | |
| National Hospital Organization Kyushu Cancer Center | Fukuoka | 811-1395 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| Osaka Prefectural Hospital Organization Osaka International Cancer Institute | Osaka | 541-8567 | Japan | Details | ||
| National Cancer Center | Goyang-si | Gyeonggi-do | 10408 | Korea, Republic of | Details | |
| Cha University Bundang Medical Center | Seongnam-si | Gyeonggi-do | 13496 | Korea, Republic of | Details | |
| Severance Hospital Younsei University Health System, | Seoul | Gyeonggi | 03722 | Korea, Republic of | Details | |
| Chonnam National University Hwasun Hospital | Hwasun | Jeollanam-do | 58128 | Korea, Republic of | Details | |
| Chungnam National University Hospital | Daejeon | Jung-gu | 35015 | Korea, Republic of | Details | |
| Severance Hospital Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Auckland City Hospital | Auckland | New Zealand | Details | |||
| Waikato Hospital | Hamilton | New Zealand | Details | |||
| Tauranga Hospital | Tauranga | 3112 | New Zealand | Details | ||
| Hospial Oncologico, Puerto Rico Medical Center | Rio Piedras | 00935 | Puerto Rico | Details | ||
| National Cancer Centre | Singapore | 169610 | Singapore | Details | ||
| The Medical Oncology Centre of Rosebank | Johannesburg | Gauteng | 2196 | South Africa | Details | |
| Wilgers Oncology Centre | Pretoria | Gauteng | 0081 | South Africa | Details | |
| Curo Oncology | Pretoria | Gauteng | 0084 | South Africa | Details | |
| West Rand Oncology Centre Flora Clinic | Roodepoort | Gauteng | 1709 | South Africa | Details | |
| Excellentis Clinical Trial Consultants | George | Western Cape | 6529 | South Africa | Details | |
| Cape Town Oncology Trials Cape Gate Oncology Centre | Kraaifontein | Western Cape | 7570 | South Africa | Details | |
| Cancercare Rondebosch Oncology | Rondebosch | Western Cape | 7700 | South Africa | Details | |
| Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Catalan Institute of Oncology | Barcelona | 08908 | Spain | Details | ||
| ICO Badalona-Hospital Universitari Germans Trias I Pujol | Barcelona | 08916 | Spain | Details | ||
| Hospital de la Santa Creu i Sant Pau | Barcelona | Spain | Details | |||
| MD Anderson Cancer Center | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Fundación Jimenez Diaz | Madrid | 28040 | Spain | Details | ||
| Centro Integral Oncologico Clara Campal | Madrid | 28050 | Spain | Details | ||
| Hospital Universitario Clinico San Carlos | Madrid | Spain | Details | |||
| Hospital Regional Universitario de Málaga | Málaga | 29010 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | Spain | Details | |||
| Hospital Universitario Miguel Servet | Zaragoza | Spain | Details | |||
| Nuffield Health Wessex Hospital | Eastleigh | Hampshire | SO53 2DW | United Kingdom | Details | |
| Edinburgh Cancer Center Western General Hospital | Edinburgh | EH4 2XU | United Kingdom | Details |