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| NCT ID | NCT04696055 |
| Title | Pilot Study of Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Bayer |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | ISR | FRA | ESP | DEU |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Arizona Cancer Center | Tucson | Arizona | 85719 | United States | Details | |
| City of Hope National Medical Center | Duarte | California | 91010-3012 | United States | Details | |
| University of Southern California | Los Angeles | California | 90033 | United States | Details | |
| University of California Irvine Medical Center | Orange | California | 92868-3201 | United States | Details | |
| Medical Oncology Hematology Consultants, PA | Newark | Delaware | 19713 | United States | Details | |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | United States | Details | |
| H. Lee Moffitt Cancer Center & Research Institute | Tampa | Florida | 33612-9416 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | United States | Details | |
| Hôpital Beaujon - Clichy | Clichy | 92110 | France | Details | ||
| Center Hospitalier Michallon - Grenoble | La Tronche | 38700 | France | Details | ||
| Hôpital Claude Huriez - Lille | Lille | 59037 | France | Details | ||
| Hôpital de la Croix Rousse | Lyon | 69004 | France | Details | ||
| Hôpital de la Timone - Marseille | Marseille | 13005 | France | Details | ||
| Hôpital Saint-Eloi | Montpellier Cedex | 34295 | France | Details | ||
| Centre François Magendie - Pessac | Pessac | 33600 | France | Details | ||
| Centre Hospitalier Universitaire de Nancy | Vandoeuvre les Nancy | 54500 | France | Details | ||
| Hôpital Paul Brousse - Villejuif | Villejuif | 94800 | France | Details | ||
| Eberhard-Karls-Universität Tübingen | Tübingen | Baden-Württemberg | 72076 | Germany | Details | |
| Klinikum der Universität München Grosshadern | München | Bayern | 81377 | Germany | Details | |
| Heinrich-Heine-Universität Düsseldorf | Düsseldorf | Nordrhein-Westfalen | 40225 | Germany | Details | |
| Universitätsklinikum Köln | Köln | Nordrhein-Westfalen | 50937 | Germany | Details | |
| Universitätsmedizin der Johannes Gutenberg Universität Mainz | Mainz | Rheinland-Pfalz | 55131 | Germany | Details | |
| Rambam Health Corporation | Haifa | 3109601 | Israel | Details | ||
| Clalit Health Services Rabin Medical Center-Beilinson Campus | Petah Tikva | 4941492 | Israel | Details | ||
| Tel-Aviv Sourasky Medical Center | Tel Aviv | 6423906 | Israel | Details | ||
| Istituto Clinico Humanitas - Humanitas Mirasole S.p.A. | Milano | Lombardia | 20089 | Italy | Details | |
| Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico | Milano | Lombardia | 20122 | Italy | Details | |
| A.O.U. Pisana | Pisa | Toscana | 56126 | Italy | Details | |
| Istituto Oncologico Veneto IRCCS (IOV) | Padova | Veneto | 35128 | Italy | Details | |
| Chiba University Hospital | Chiba-shi | Chiba | 260-8677 | Japan | Details | |
| National Cancer Center Hospital East | Kashiwa-shi | Chiba | 277-8577 | Japan | Details | |
| Japanese Red Cross Society Musashino Red Cross Hospital | Musashino-shi | Tokyo | 180-8610 | Japan | Details | |
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 110-744 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 138-736 | Korea, Republic of | Details | ||
| Institut Català d'Oncologia Hospitalet | Hospitalet de Llobregat | Barcelona | 08907 | Spain | Details | |
| Hospital Clínic i Provincial de Barcelona | Barcelona | 8036 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañón | Digestivo | Madrid | 28007 | Spain | Details |