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| NCT ID | NCT04725188 |
| Title | Pembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002, KEYVIBE-002) |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | POL | ITA | ISR | FRA | FIN | ESP | DNK | DEU | CHE | BRA | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Cedars-Sinai Medical Center ( Site 2522) | Los Angeles | California | 90048 | United States | Details | |
| Illinois Cancer Care ( Site 2534) | Peoria | Illinois | 61615 | United States | Details | |
| Baptist Health Lexington-Research ( Site 2502) | Lexington | Kentucky | 40503 | United States | Details | |
| University of Maryland ( Site 2528) | Baltimore | Maryland | 21201 | United States | Details | |
| Hattiesburg Clinic Hematology/Oncology ( Site 2511) | Hattiesburg | Mississippi | 39401 | United States | Details | |
| Mercy Research - David C. Pratt Cancer Center ( Site 2532) | Saint Louis | Missouri | 63109 | United States | Details | |
| Mercy Research - Cancer and Hematology Center ( Site 2535) | Springfield | Missouri | 65804 | United States | Details | |
| Montefiore- Einstein Center for Cancer Care-Oncology ( Site 2509) | Bronx | New York | 10461 | United States | Details | |
| University of Cincinnati Medical Center-University of Cincinnati Cancer Center ( Site 2526) | Cincinnati | Ohio | 45219 | United States | Details | |
| St Francis Cancer Center-Research Office ( Site 2531) | Greenville | South Carolina | 29607 | United States | Details | |
| Centro de Oncología e Investigación de Buenos Aires ( Site 0008) | Berazategui | Buenos Aires | B1884BBF | Argentina | Details | |
| Hospital Privado de Comunidad ( Site 0004) | Mar del Plata | Buenos Aires | 7600 | Argentina | Details | |
| Instituto de Investigaciones Clínicas Mar del Plata ( Site 0002) | Mar del Plata | Buenos Aires | 7600 | Argentina | Details | |
| Instituto de Oncología de Rosario ( Site 0003) | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Hospital Privado Universitario de Córdoba ( Site 0001) | Cordoba | 5016 | Argentina | Details | ||
| Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0005) | La Rioja | F5300COE | Argentina | Details | ||
| Canberra Hospital ( Site 0104) | Canberra | Australian Capital Territory | 2605 | Australia | Details | |
| Gold Coast University Hospital-Clinical Trials Service ( Site 0106) | Southport | Queensland | 4215 | Australia | Details | |
| Fiona Stanley Hospital-Medical Oncology ( Site 0102) | Murdoch | Western Australia | 6150 | Australia | Details | |
| Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0203) | Linz | Oberosterreich | 4020 | Austria | Details | |
| Medizinische Universität Graz ( Site 0201) | Graz | Steiermark | 8036 | Austria | Details | |
| Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0204) | Wien | 1210 | Austria | Details | ||
| AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 0333) | Mechelen | Antwerpen | 2800 | Belgium | Details | |
| UZ Brussel ( Site 0336) | Brussels | Bruxelles-Capitale, Region De | 1090 | Belgium | Details | |
| Grand Hôpital de Charleroi-Oncology & Hematology ( Site 0337) | Charleroi | Hainaut | 6000 | Belgium | Details | |
| Jessa Ziekenhuis-Pulmonology & Thoracic Oncology ( Site 0338) | Hasselt | Limburg | 3500 | Belgium | Details | |
| AZ Nikolaas ( Site 0334) | Sint-Niklaas | Oost-Vlaanderen | 1932 | Belgium | Details | |
| Hospital Nossa Senhora da Conceição ( Site 0403) | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details | |
| ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO-Pesquisa Clinica ( Site 0400) | São Paulo | Sao Paulo | 01246-000 | Brazil | Details | |
| Centro de Tratamento de Tumores Botafogo - CTTB-Pesquisa Clínica ( Site 0402) | Rio de Janeiro | 22250-905 | Brazil | Details | ||
| Hospital Paulistano ( Site 0406) | Sao Paulo | 01321-000 | Brazil | Details | ||
| Rigshospitalet ( Site 0702) | Copenhagen | Hovedstaden | 2100 | Denmark | Details | |
| Odense Universitetshospital ( Site 0700) | Odense | Syddanmark | 5000 | Denmark | Details | |
| Sygehus Soenderjylland-Kraeftambulatoriet ( Site 0705) | Soenderborg | Syddanmark | 6400 | Denmark | Details | |
| Tampereen yliopistollinen sairaala-Oncology ( Site 0906) | Tampere | Pirkanmaa | 33520 | Finland | Details | |
| Vaasan Keskussairaala ( Site 0903) | Vaasa | Pohjanmaa | 65130 | Finland | Details | |
| Oulun yliopistollinen sairaala ( Site 0902) | Oulu | Pohjois-Pohjanmaa | 90220 | Finland | Details | |
| Turku University Hospital-The Department of Pulmonary Medicine ( Site 0905) | Turku | Varsinais-Suomi | 20520 | Finland | Details | |
| Nouvel Hôpital Civil (NHC) ( Site 1000) | Strasbourg | Alsace | 67000 | France | Details | |
| Institut Bergonié - Centre Régional de Lutte Contre Le Cance-Medical Oncology ( Site 1009) | Bordeaux | Aquitaine | 33000 | France | Details | |
| Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre ( Site 1006) | Caen | Calvados | 14033 | France | Details | |
| CHU de Toulouse - Hopital Larrey-service de pneumologie ( Site 1008) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Clinique Ambroise Paré ( Site 1007) | Beuvry | Pas-de-Calais | 62660 | France | Details | |
| Centre Hospitalier du Mans ( Site 1002) | Le Mans | Sarthe | 72037 | France | Details | |
| Gustave Roussy ( Site 1005) | Villejuif | Val-de-Marne | 94800 | France | Details | |
| HIA Sainte Anne ( Site 1003) | Toulon | Var | 83800 Cedex 9 | France | Details | |
| Centre Hospitalier d'Avignon-Service d'Oncologie médicale et d'hématologie clinique ( Site 1004) | Avignon | Vaucluse | 84000 | France | Details | |
| Onkologie Ravensburg ( Site 1104) | Ravensburg | Baden-Wurttemberg | 88212 | Germany | Details | |
| Klinikverbund Allgaeu gGmbH ( Site 1109) | Immenstadt im Allgäu | Bayern | 87509 | Germany | Details | |
| Helios Dr. Horst Schmidt Kliniken ( Site 1108) | Wiesbaden | Hessen | 65199 | Germany | Details | |
| Universitätsklinikum Bonn ( Site 1111) | Bonn | Nordrhein-Westfalen | 53127 | Germany | Details | |
| Helios Klinikum Emil von Behring Berlin-Zehlendorf ( Site 1106) | Berlin | 14165 | Germany | Details | ||
| Soroka Medical Center ( Site 1202) | Be'er Sheva | 8410101 | Israel | Details | ||
| Rambam Health Care Campus-Oncology ( Site 1203) | Haifa | 3109601 | Israel | Details | ||
| Shaare Zedek Medical Center-Oncology ( Site 1206) | Jerusalem | 9103102 | Israel | Details | ||
| Sourasky Medical Center ( Site 1205) | Tel Aviv | 6423906 | Israel | Details | ||
| Azienda Ospedaliera S. Giovanni Addolorata-Oncologia Medica ( Site 1307) | Roma | Lazio | 00184 | Italy | Details | |
| Azienda Ospedaliera Dei Colli-U.O.C Pneumologia Oncologica DH PNL ONC ( Site 1308) | Naples | Napoli | 80131 | Italy | Details | |
| CRO-IRCCS-medical oncology ( Site 1304) | Aviano | Pordenone | 33081 | Italy | Details | |
| Azienda Sanitaria Ospedaliera S Luigi Gonzaga-Oncologia Polmonare ( Site 1300) | Orbassano | Torino | 10043 | Italy | Details | |
| Azienda Ospedaliera Universitaria Careggi-SOD ONCOLOGIA MEDICA ( Site 1306) | Firenze | Toscana | 50134 | Italy | Details | |
| Ospedale San Raffaele-Oncologia Medica ( Site 1305) | Milano | 20132 | Italy | Details | ||
| Istituto Europeo di Oncologia IRCCS-Divisione di Oncologia Toracica ( Site 1301) | Milano | 20141 | Italy | Details | ||
| Fondazione Policlinico Universitario Agostino Gemelli-Medical Oncology ( Site 1303) | Roma | 00168 | Italy | Details | ||
| Chungbuk National University Hospital-Internal medicine ( Site 2004) | Cheongju-si | Chungbuk | 28644 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital ( Site 2003) | Seongnam | Kyonggi-do | 13620 | Korea, Republic of | Details | |
| The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 2005) | Suwon-si | Kyonggi-do | 16247 | Korea, Republic of | Details | |
| Asan Medical Center-Oncology ( Site 2000) | Songpagu | Seoul | 05505 | Korea, Republic of | Details | |
| Hospital Sultan Ismail ( Site 1503) | Johor Bahru | Johor | 81100 | Malaysia | Details | |
| University Malaya Medical Centre ( Site 1501) | Lembah Pantai | Kuala Lumpur | 59100 | Malaysia | Details | |
| Hospital Tengku Ampuan Afzan ( Site 1500) | Kuantan | Pahang | 25100 | Malaysia | Details | |
| Beacon Hospital Sdn Bhd ( Site 1504) | Petaling Jaya | Selangor | 46050 | Malaysia | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Przychodnia Lekarska KOMED ( Site 1704) | Konin | Wielkopolskie | 62-500 | Poland | Details | |
| Saint Petersburg State University-Clinic of advanced medical technologies n. a. Nicolay I. Pirogov ( | Saint Petersburg | Leningradskaya Oblast | 190020 | Russian Federation | Details | |
| Saint-Petersburg City Clinical Oncology Dispensary-Department of chemotherapy ( Site 1911) | Saint Petersburg | Leningradskaya Oblast | 198255 | Russian Federation | Details | |
| Hadassah Medical-Oncology department ( Site 1912) | Moscow | Moskovskaya Oblast | 121205 | Russian Federation | Details | |
| Moscow Clinical Research Center-Chemotherapy department ( Site 1910) | Moscow | Moskva | 111123 | Russian Federation | Details | |
| Central Clinical Hospital of the Presidential Administrative Department ( Site 1902) | Moscow | Moskva | 121359 | Russian Federation | Details | |
| Nizhegorodsky Regional Oncology Dispensary, Branch #2-chemotherapy ( Site 1909) | Nizhniy Novgorod | Nizhegorodskaya Oblast | 603081 | Russian Federation | Details | |
| Budgetary Healthcare Institution of Omsk Region Clinical Oncology Dispensary ( Site 1908) | Omsk | Omskaya Oblast | 644013 | Russian Federation | Details | |
| N.N.Petrov Research Institute of Oncology-Department of Chemotherapy and Innovative Technologies ( S | Saint Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details | |
| GBUZ LOKB-Oncology department #1 ( Site 1905) | Saint-Petersburg | Sankt-Peterburg | 194291 | Russian Federation | Details | |
| HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Sit | Barcelona | Cataluna | 08036 | Spain | Details | |
| Hospital de la Santa Creu i Sant Pau-Oncología Médica ( Site 2102) | Barcelona | Cataluna | 08041 | Spain | Details | |
| HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 2101) | Madrid | 28009 | Spain | Details | ||
| Hospital Universitario Virgen de Valme-Departamento de Oncologia ( Site 2103) | Sevilla | 41014 | Spain | Details | ||
| Ospedale Regionale Bellinzona e Valli ( Site 2203) | Bellinzona | Ticino | 6500 | Switzerland | Details | |
| Chang Gung Memorial Hospital at Kaohsiung ( Site 2303) | Kaohsiung Niao Sung Dist | Kaohsiung | 83301 | Taiwan | Details | |
| Taichung Veterans General Hospital-Chest ( Site 2307) | Taichung | 40705 | Taiwan | Details | ||
| NATIONAL CHENG-KUNG UNI. HOSP.-clinical trial center ( Site 2302) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital-Oncology ( Site 2304) | Taipei | 10002 | Taiwan | Details | ||
| Mackay Memorial Hospital-Chest Medicine ( Site 2305) | Taipei | 10449 | Taiwan | Details | ||
| Chulalongkorn University ( Site 2403) | Bangkok | Krung Thep Maha Nakhon | 10330 | Thailand | Details | |
| Faculty of Medicine Siriraj Hospital ( Site 2400) | Bangkok | Krung Thep Maha Nakhon | 10700 | Thailand | Details |