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| NCT ID | NCT04941287 |
| Title | Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of A Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic Hospital in Arizona | Phoenix | Arizona | 85054 | United States | Details | |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | United States | Details | |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | United States | Details | |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | United States | Details | |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | United States | Details | |
| UCHealth University of Colorado Hospital | Aurora | Colorado | 80045 | United States | Details | |
| UM Sylvester Comprehensive Cancer Center at Aventura | Aventura | Florida | 33180 | United States | Details | |
| UM Sylvester Comprehensive Cancer Center at Coral Gables | Coral Gables | Florida | 33146 | United States | Details | |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach | Florida | 33442 | United States | Details | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | United States | Details | |
| UM Sylvester Comprehensive Cancer Center at Kendall | Miami | Florida | 33176 | United States | Details | |
| UM Sylvester Comprehensive Cancer Center at Plantation | Plantation | Florida | 33324 | United States | Details | |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | United States | Details | |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60611 | United States | Details | |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | United States | Details | |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | United States | Details | |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | United States | Details | |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | United States | Details | |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | United States | Details | |
| M D Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | United States | Details | |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | United States | Details | |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | United States | Details | |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | United States | Details |