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NCT ID NCT04988295
Title A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure (MARIPOSA-2)
Acronym MARIPOSA-2
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Janssen Research & Development, LLC
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | TUR | SWE | POL | NLD | ITA | ISR | GBR | FRA | ESP | DNK | DEU | CZE | CAN | BRA | BGR | BEL | ARG

Facility Status City State Zip Country Details
Southern Cancer Center, PC Mobile Alabama 36608 United States Details
Arizona Oncology Associates Tucson Arizona 85711 United States Details
City of Hope Duarte California 91010 United States Details
Cedars Sinai Medical Center Los Angeles California 90048 United States Details
University of California Irvine Orange California 92868 United States Details
Rocky Mountain Cancer Centers Colorado Springs Colorado 80907 United States Details
Holy Cross Hospital - Michael and Dianne Bienes Comprehensive Cancer Center Fort Lauderdale Florida 33308 United States Details
University Cancer And Blood Center LLC Athens Georgia 30607 United States Details
University of Mississippi Medical Center Jackson Mississippi 39216 United States Details
Nebraska Cancer Specialists Grand Island Nebraska 68803 United States Details
Astera Cancer Care East Brunswick New Jersey 08816 United States Details
TriHealth Network Cincinnati Ohio 45220 United States Details
Providence Portland Medical Center Portland Oregon 97213 United States Details
Kaiser Permanente Northwest Portland Oregon 97227 United States Details
Alliance Cancer Specialists Horsham Pennsylvania 19044 United States Details
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15232 United States Details
Baptist Cancer Center Memphis Tennessee 38120 United States Details
Texas Oncology-Medical City Dallas Dallas Texas 75230 United States Details
Texas Oncology Baylor Charles A Sammons Cancer Center Dallas Texas 75246 United States Details
Texas Oncology Grapevine Texas 76051 United States Details
Oncology Consultants - Texas Houston Texas 77030 United States Details
Texas Oncology - Northeast Longview Texas 75601 United States Details
University of Vermont Medical Center Burlington Vermont 05401 United States Details
University of Virginia Charlottesville Virginia 22908 United States Details
Virginia Cancer Specialists Fairfax Virginia 22031 United States Details
Blue Ridge Cancer Care Wytheville Virginia 24382 United States Details
NorthWest Medical Specialties, PLLC Puyallup Washington 98373 United States Details
Compass Oncology Vancouver Washington 98684 United States Details
CINME Centro de Investigaciones Metabolicas Caba C1027AAP Argentina Details
IADT Instituto Argentino de Diagnostico y Tratamiento Caba C1122 Argentina Details
Centro Medico Fleischer Caba C1414 Argentina Details
CEMIC (Centro de Educación Médica e Investigaciones Clínicas) Caba C1431FWO Argentina Details
Hospital Privado Universitario De Cordoba Cordoba X5016KEH Argentina Details
Cemaic Centro Privado de Especialidades Medicas Ambulatorias e Investigacion Clinica Córdoba 5000 Argentina Details
Hospital Privado de la Comunidad Mar del Plata B7602CBM Argentina Details
Clínica Viedma Viedma R8500ACE Argentina Details
Grand Hopital de Charleroi, site Notre Dame Charleroi 6000 Belgium Details
UZA Edegem 2650 Belgium Details
UZ Gent Gent 9000 Belgium Details
Jessa Ziekenhuis - Campus Virga Jesse Hasselt 3500 Belgium Details
UZ Leuven Leuven 3000 Belgium Details
CHU Sart-Tilman Liege 4000 Belgium Details
Clinique Saint Pierre Ottignies 1340 Belgium Details
Cetus Oncologia Belo Horizonte 30110-017 Brazil Details
CIONC Centro Integrado de Oncologia de Curitiba Curitiba 80810 050 Brazil Details
Ynova Pesquisa Clinica Florianopolis 88020-210 Brazil Details
Fundação São Francisco Xavier Ipatinga 35162 189 Brazil Details
UPCO Unidade de Pesquisa Clinica em Oncologia Pelotas 96020 080 Brazil Details
Associacao Hospitalar Moinhos de Vento Porto Alegre 90035-001 Brazil Details
Hospital Ernesto Dornelles Porto Alegre 90160-093 Brazil Details
Oncoclinicas Rio de Janeiro S A Rio de Janeiro 22250-905 Brazil Details
Instituto D Or de Pesquisa e Ensino IDOR Rio de Janeiro 22281 100 Brazil Details
Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI) Rio de Janeiro 22775 001 Brazil Details
Nucleo de Oncologia da Bahia Salvador 40170 110 Brazil Details
Hospital Sao Rafael Salvador 41253-190 Brazil Details
CEPHO Centro de Estudos e Pesquisa de Hematologia e Oncologia Santo Andre 09060 650 Brazil Details
Real e Benemerita Associacao Portuguesa de Beneficencia Sao Paulo 01323 900 Brazil Details
Hospital Paulistano Sao Paulo 01323-000 Brazil Details
Hospital Alemao Oswaldo Cruz Sao Paulo 01327 001 Brazil Details
Fundacao Antonio Prudente A C Camargo Cancer Center Sao Paulo 01509 900 Brazil Details
Onco Star SP Oncologia Ltda Sao Paulo 04543-000 Brazil Details
IOS - Instituto de Oncologia de Sorocaba Dr. Gilson Delgado Sorocaba 18030-005 Brazil Details
Hospital Nove de Julho São Paulo 01409902 Brazil Details
COT - Centro Oncologico do Triangulo S.A Uberlandia 38408-150 Brazil Details
Multifunctional Hospital for Active Treatment 'Serdika' Sofia 1303 Bulgaria Details
Multiprofile Hospital for Active Treatment 'Tokuda Hospital Sofia' Sofia 1407 Bulgaria Details
Specialized Hospital for Active Treatment in Oncology Sofia 1756 Bulgaria Details
UMHAT Sofia Med Sofia 1797 Bulgaria Details
Tom Baker Cancer Centre Calgary Alberta T2N 4N2 Canada Details
British Columbia Cancer Agency Vancouver British Columbia V5Z 4E6 Canada Details
McGill University Health Centre Montreal Quebec H4A 3J1 Canada Details
Cancer Hospital, Chinese Academy of Medical Sciences Beijing 100021 China Details
Peking University People s Hospital Beijing 100044 China Details
Beijing Cancer Hospital Beijing 100142 China Details
Chinese PLA General Hospital Beijing 100853 China Details
Beijing Chest hospital, Capital medical university Beijing 101199 China Details
Hunan Cancer hospital Changsha 410013 China Details
Sichuan Cancer Hospital Chengdu 610041 China Details
West China Hospital Sichuan University Chengdu 610041 China Details
Chongqing University Cancer Hospital Chongqing 400000 China Details
Southwest Hospital ChongQing 400038 China Details
The First Affiliated Hospital Sun Yat sen University Guang Zhou 510080 China Details
Sun Yat-Sen Memorial Hospital Sun Yat-sen University Guangzhou 510120 China Details
Zhejiang Cancer Hospital Hang Zhou 310022 China Details
Second Affiliated Hospital, School of Medicine, Zhejiang University Hangzhou 310009 China Details
The Second Affiliated Hospital of Zhejiang University College of Medicine Hangzhou 310009 China Details
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Hangzhou 310016 China Details
Harbin medical university cancer hospital Harbin 150000 China Details
Huizhou Municipal Central Hospital Huizhou 516001 China Details
Taizhou Hospital of Zhejiang Province Linhai 317000 China Details
Affiliated Hospital of North Sichuan Medical College Nanchong China Details
Ruijin Hospital Shanghai Jiao Tong University Shanghai 200025 China Details
Fudan University Shanghai Cancer Center Shanghai 200032 China Details
Shanghai East Hospital Shanghai 310000 China Details
Shenzhen university General Hospital Shenzhen 518055 China Details
Cancer Hospital Chinese Academy of Medical Sciences Shenzhen 518116 China Details
Tianjin Medical University General Hospital Tianjin 300052 China Details
Weifang People's Hospital Weifang 261000 China Details
The First Affiliated Hospital of Xian Jiaotong University XI An 710061 China Details
Yantai Yuhuangding Hospital Yantai 264000 China Details
Daping Hospital Army Characteristic Medical Center Yuzhong District 400042 China Details
Henan Cancer Hospital Zhengzhou 450008 China Details
Fakultni nemocnice Olomouc - I.P.Pavlova 6 Olomouc 775 20 Czechia Details
Vitkovicka nemocnice a.s. Ostrava- Vitkovice 70300 Czechia Details
Fakultni nemocnice Plzen Plzen 30599 Czechia Details
Rigshospitalet Copenhagen DK 2100 Denmark Details
Institut Sainte Catherine Avignon Cedex 9 84918 France Details
Hospices Civils de Lyon HCL Bron 69500 France Details
CHU de Grenoble Hopital Albert Michallon La Tronche 38700 France Details
Centre Hospitalier du Mans le Mans 72000 France Details
CHR Hôpital Calmette Lille 59000 France Details
Hopital Nord Marseille Cedex 20 13915 France Details
CHU de Montpellier - Arnaud de Villeneuve Montpellier Cedex 5 34295 France Details
Institut Curie Paris 75005 France Details
CHU Bordeaux Pessac 33604 France Details
CHRU Hopital de Pontchaillou Rennes 35033 France Details
CHU Nantes Sain-Herblain 44800 France Details
Nouvel Hopital Civil - CHU Strasbourg Strasbourg cedex 67091 France Details
CHU Bretonneau Tours 37000 France Details
Evangelische Lungenklinik Berlin Berlin 13125 Germany Details
Asklepios Klinikum Harburg Hamburg 21075 Germany Details
Thoraxklinik am Universitatsklinikum Heidelberg Heidelberg 69126 Germany Details
Onkologische Schwerpunktpraxis Heilbronn 74072 Germany Details
POIS Sachsen GmbH iG Leipzig 04357 Germany Details
Bethanien Krankenhaus Moers 47441 Germany Details
Klinikum der Universitaet Muenchen München 80336 Germany Details
Oncologianova GmbH Recklinghausen 45659 Germany Details
Universitaetsklinikum Regensburg Regensburg 93053 Germany Details
Queen Mary Hospital Hong Kong 999077 Hong Kong Details
Health Care Global Enterprises pvt Ltd Bangalore 560027 India Details
Artemis Hospital Gurugram 122001 India Details
Tata Medical Center Kolkata 700160 India Details
Tata Memorial Hospital Mumbai 400012 India Details
HCG Manavta Cancer Centre Nasik 422002 India Details
Rajiv Gandhi Cancer Institute and Research Centre New Delh 110085 India Details
Noble Hospital Pvt Ltd Pune 411013 India Details
Bhaktivedanta Hospital & Research Institute Thane 411107 India Details
Soroka University Medical Center Beersheba 84101 Israel Details
Rambam Health Corporation Haifa 3109601 Israel Details
Shaare Zedek Medical Center Jerusalem 91031 Israel Details
Meir Medical Center Kfar Saba 44281 Israel Details
Rabin Medical Center Petah Tikva 49100 Israel Details
Chaim Sheba Medical Center Ramat Gan 5262100 Israel Details
Tel-Aviv Sourasky Medical Center Tel-Aviv 6423906 Israel Details
CRO IRCCS Istituto Nazionale Tumori Aviano 33081 Italy Details
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Meldola 47014 Italy Details
Istituto Europeo di Oncologia Milano 20141 Italy Details
Azienda Ospedaliero-Universitaria Di Parma Parma 43126 Italy Details
Ospedale S. Maria Delle Croci Ravenna 48121 Italy Details
Istituto Nazionale Tumori Regina Elena Roma 00144 Italy Details
Policlinico G.B.Rossi Verona 37134 Italy Details
National Hospital Organization Shibukawa Medical Center Gunma 377-0280 Japan Details
Hyogo Cancer Center Hyogo 673-8558 Japan Details
Kanagawa Cancer Center Kanagawa 241-8515 Japan Details
Kobe City Medical Center General Hospital Kobe City 650 0047 Japan Details
Kurume University Hospital Kurume 830-0011 Japan Details
National Hospital Organization Nagoya Medical Center Nagoya-shi 460-0001 Japan Details
Niigata Cancer Center Hospital Niigata 951-8566 Japan Details
Osaka International Cancer Institute Osaka City 541 8567 Japan Details
Shizuoka Cancer Center Shizuoka 411 8777 Japan Details
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Tokyo 113 8677 Japan Details
The Cancer Institute Hospital of JFCR Tokyo 135 8550 Japan Details
Ehime University Hospital Toon-shi 791-0295 Japan Details
Wakayama Medical University Hospital Wakayama 641 8510 Japan Details
National Hospital Organization Iwakuni Clinical Center Yamaguchi 740-8510 Japan Details
National Hospital Organization Yamaguchi Ube Medical Center Yamaguchi 755-0241 Japan Details
National Cancer Center Gyeonggi-do 10408 Korea, Republic of Details
CHA Bundang Medical Center, CHA University Gyeonggi-do 13496 Korea, Republic of Details
Seoul National University Bundang Hospital Gyeonggi-do 13620 Korea, Republic of Details
GyeongSang National University Hospital Gyeongsangnam-do 52727 Korea, Republic of Details
Korea University Anam Hospital Seoul 02841 Korea, Republic of Details
Severance Hospital Yonsei University Health System Seoul 03722 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
Samsung Medical Center Seoul 06351 Korea, Republic of Details
The Catholic University of Korea Seoul St Mary s Hospital Seoul 06591 Korea, Republic of Details
University Malaya Medical Centre Kuala Lumpur Malaysia Details
Hospital Tengku Ampuan Afzan Kuantan 25100 Malaysia Details
Beacon Hospital Sdn Bhd Petaling Jaya 46050 Malaysia Details
Subang Jaya Medical Centre Subang Jaya 47500 Malaysia Details
Mount Miriam Cancer Hospital Tanjung Bungah 11200 Malaysia Details
Hospital Civil de Guadalajara Fray Antonio Alcalde Guadalajara 44280 Mexico Details
CIMOVA, Morals Vargas Centro de Investigación SC Leon 37000 Mexico Details
Health Pharma Professional Research Mexico 03100 Mexico Details
Instituto Nacional de Cancerologia Mexico 14080 Mexico Details
Oncologia Integral Satelite Naucalpan 53100 Mexico Details
VUMC Amsterdam Amsterdam 1081 HV Netherlands Details
Ziekenhuis St Jansdal Harderwijk 3844 DG Netherlands Details
Erasmus MC Rotterdam 3015 GD Netherlands Details
Centrum Onkologii im. Prof. F. Lukaszczyka Bydgoszcz 85-796 Poland Details
Uniwersyteckie Centrum Kliniczne Gdansk 80-952 Poland Details
Szpitale Pomorskie Sp z o o Gdynia 81-519 Poland Details
Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie Olsztyn 10-357 Poland Details
Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandow Poznan 60 569 Poland Details
Private Specialist Hospitals - MedPolonia Poznan 60-693 Poland Details
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy Warszawa 02-781 Poland Details
Centro Hospitalar Lisboa Norte EPE - Hospital Pulido Valente Lisboa 1769-001 Portugal Details
Hospital Beatriz Angelo Loures 2674 514 Portugal Details
Centro Hospitalar Universitario do Porto, EPE Porto 4099-001 Portugal Details
Instituto Portugues de Oncologia Porto 4200072 Portugal Details
Pan American Center for Oncology Trials LLC Rio Piedras 00917 Puerto Rico Details
City Clinical Hospital #1 Nalchik 360000 Russian Federation Details
Llc, Eurocityclinic Saint Petersburg 197022 Russian Federation Details
Hosp Univ A Coruna A Coruña 15006 Spain Details
Hosp. de La Santa Creu I Sant Pau Barcelona 08025 Spain Details
Hosp. Univ. Quiron Dexeus Barcelona 08028 Spain Details
Hosp Univ Vall D Hebron Barcelona 08035 Spain Details
Hosp Clinic de Barcelona Barcelona 08036 Spain Details
Hosp. Univ. Insular de Gran Canaria Las Palmas de Gran Canaria 35016 Spain Details
Hosp. Gral. Univ. Gregorio Maranon Madrid 28007 Spain Details
Hosp Univ Fund Jimenez Diaz Madrid 28040 Spain Details
Hosp. Univ. 12 de Octubre Madrid 28041 Spain Details
Hosp. Univ. La Paz Madrid 28046 Spain Details
Hosp Univ Hm Sanchinarro Madrid 28050 Spain Details
Hosp. Univ. Pta. de Hierro Majadahonda Majadahonda 28222 Spain Details
Hosp Regional Univ de Malaga Málaga 29010 Spain Details
Clinica Univ. de Navarra Pamplona 31008 Spain Details
Hosp. Virgen Del Rocio Seville 41013 Spain Details
Hosp. Gral. Univ. Valencia Valencia 46014 Spain Details
Hosp. Univ. I Politecni La Fe Valencia 46026 Spain Details
Sahlgrenska Universitetssjukhuset Goteborg 413 45 Sweden Details
Linkoping University Hospital Linkoping 581 85 Sweden Details
Skanes universitetssjukhus Lund 221 85 Sweden Details
Norrlands Universitetssjukhus Umea 901 85 Sweden Details
Akademiska Sjukhuset Uppsala 75181 Sweden Details
Changhua Christian Hospital Changhua 500 Taiwan Details
Kaohsiung Medical University Chung Ho Memorial Hospital Kaohsiung 807 Taiwan Details
Taipei Medical University Shuang Ho Hospital New Taipei City 23561 Taiwan Details
Chung Shan Medical University Hospital Taichung 402 Taiwan Details
Taichung Veterans General Hospital Taichung 40705 Taiwan Details
National Cheng Kung University Hospital Tainan 704 Taiwan Details
National Taiwan University Hospital Taipei 100 Taiwan Details
Adana City Hospital Adana 01060 Turkey Details
Memorial Ankara Hastanesi Ankara 06520 Turkey Details
Gazi University Hospital Ankara 06560 Turkey Details
Ankara Bilkent City Hospital Ankara 06800 Turkey Details
Trakya University Medical Faculty Edirne 22030 Turkey Details
Istanbul University Cerrahpasa Medical Faculty Istanbul 34098 Turkey Details
Bakirkoy Training and Research Hospital Istanbul 34147 Turkey Details
Medipol Mega University Hospital Istanbul 34214 Turkey Details
Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi Istanbul 34722 Turkey Details
Medical Point Izmir 35575 Turkey Details
Velindre Hospital Cardiff CF14 2TL United Kingdom Details
Edinburgh Cancer Centre Western General Edinburgh EH4 2XU United Kingdom Details
UCL Cancer Institute London NW1 2PG United Kingdom Details
Guys and St Thomas NHS Foundation Trust London SE1 9RT United Kingdom Details
The Royal Marsden NHS Trust London SW3 6JJ United Kingdom Details
The Christie Nhs Foundation Trust Manchester M20 4BX United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field