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NCT ID | NCT04988295 |
Title | A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure (MARIPOSA-2) |
Acronym | MARIPOSA-2 |
Recruitment | Active, not recruiting |
Gender | both |
Phase | Phase III |
Variant Requirements | No |
Sponsors | Janssen Research & Development, LLC |
Indications | |
Therapies | |
Age Groups: | adult | senior |
Covered Countries | USA | TUR | SWE | POL | NLD | ITA | ISR | GBR | FRA | ESP | DNK | DEU | CZE | CAN | BRA | BGR | BEL | ARG |
Facility | Status | City | State | Zip | Country | Details |
---|---|---|---|---|---|---|
Southern Cancer Center, PC | Mobile | Alabama | 36608 | United States | Details | |
Arizona Oncology Associates | Tucson | Arizona | 85711 | United States | Details | |
City of Hope | Duarte | California | 91010 | United States | Details | |
Cedars Sinai Medical Center | Los Angeles | California | 90048 | United States | Details | |
University of California Irvine | Orange | California | 92868 | United States | Details | |
Rocky Mountain Cancer Centers | Colorado Springs | Colorado | 80907 | United States | Details | |
Holy Cross Hospital - Michael and Dianne Bienes Comprehensive Cancer Center | Fort Lauderdale | Florida | 33308 | United States | Details | |
University Cancer And Blood Center LLC | Athens | Georgia | 30607 | United States | Details | |
University of Mississippi Medical Center | Jackson | Mississippi | 39216 | United States | Details | |
Nebraska Cancer Specialists | Grand Island | Nebraska | 68803 | United States | Details | |
Astera Cancer Care | East Brunswick | New Jersey | 08816 | United States | Details | |
TriHealth Network | Cincinnati | Ohio | 45220 | United States | Details | |
Providence Portland Medical Center | Portland | Oregon | 97213 | United States | Details | |
Kaiser Permanente Northwest | Portland | Oregon | 97227 | United States | Details | |
Alliance Cancer Specialists | Horsham | Pennsylvania | 19044 | United States | Details | |
University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
Baptist Cancer Center | Memphis | Tennessee | 38120 | United States | Details | |
Texas Oncology-Medical City Dallas | Dallas | Texas | 75230 | United States | Details | |
Texas Oncology Baylor Charles A Sammons Cancer Center | Dallas | Texas | 75246 | United States | Details | |
Texas Oncology | Grapevine | Texas | 76051 | United States | Details | |
Oncology Consultants - Texas | Houston | Texas | 77030 | United States | Details | |
Texas Oncology - Northeast | Longview | Texas | 75601 | United States | Details | |
University of Vermont Medical Center | Burlington | Vermont | 05401 | United States | Details | |
University of Virginia | Charlottesville | Virginia | 22908 | United States | Details | |
Virginia Cancer Specialists | Fairfax | Virginia | 22031 | United States | Details | |
Blue Ridge Cancer Care | Wytheville | Virginia | 24382 | United States | Details | |
NorthWest Medical Specialties, PLLC | Puyallup | Washington | 98373 | United States | Details | |
Compass Oncology | Vancouver | Washington | 98684 | United States | Details | |
CINME Centro de Investigaciones Metabolicas | Caba | C1027AAP | Argentina | Details | ||
IADT Instituto Argentino de Diagnostico y Tratamiento | Caba | C1122 | Argentina | Details | ||
Centro Medico Fleischer | Caba | C1414 | Argentina | Details | ||
CEMIC (Centro de Educación Médica e Investigaciones Clínicas) | Caba | C1431FWO | Argentina | Details | ||
Hospital Privado Universitario De Cordoba | Cordoba | X5016KEH | Argentina | Details | ||
Cemaic Centro Privado de Especialidades Medicas Ambulatorias e Investigacion Clinica | Córdoba | 5000 | Argentina | Details | ||
Hospital Privado de la Comunidad | Mar del Plata | B7602CBM | Argentina | Details | ||
Clínica Viedma | Viedma | R8500ACE | Argentina | Details | ||
Grand Hopital de Charleroi, site Notre Dame | Charleroi | 6000 | Belgium | Details | ||
UZA | Edegem | 2650 | Belgium | Details | ||
UZ Gent | Gent | 9000 | Belgium | Details | ||
Jessa Ziekenhuis - Campus Virga Jesse | Hasselt | 3500 | Belgium | Details | ||
UZ Leuven | Leuven | 3000 | Belgium | Details | ||
CHU Sart-Tilman | Liege | 4000 | Belgium | Details | ||
Clinique Saint Pierre | Ottignies | 1340 | Belgium | Details | ||
Cetus Oncologia | Belo Horizonte | 30110-017 | Brazil | Details | ||
CIONC Centro Integrado de Oncologia de Curitiba | Curitiba | 80810 050 | Brazil | Details | ||
Ynova Pesquisa Clinica | Florianopolis | 88020-210 | Brazil | Details | ||
Fundação São Francisco Xavier | Ipatinga | 35162 189 | Brazil | Details | ||
UPCO Unidade de Pesquisa Clinica em Oncologia | Pelotas | 96020 080 | Brazil | Details | ||
Associacao Hospitalar Moinhos de Vento | Porto Alegre | 90035-001 | Brazil | Details | ||
Hospital Ernesto Dornelles | Porto Alegre | 90160-093 | Brazil | Details | ||
Oncoclinicas Rio de Janeiro S A | Rio de Janeiro | 22250-905 | Brazil | Details | ||
Instituto D Or de Pesquisa e Ensino IDOR | Rio de Janeiro | 22281 100 | Brazil | Details | ||
Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI) | Rio de Janeiro | 22775 001 | Brazil | Details | ||
Nucleo de Oncologia da Bahia | Salvador | 40170 110 | Brazil | Details | ||
Hospital Sao Rafael | Salvador | 41253-190 | Brazil | Details | ||
CEPHO Centro de Estudos e Pesquisa de Hematologia e Oncologia | Santo Andre | 09060 650 | Brazil | Details | ||
Real e Benemerita Associacao Portuguesa de Beneficencia | Sao Paulo | 01323 900 | Brazil | Details | ||
Hospital Paulistano | Sao Paulo | 01323-000 | Brazil | Details | ||
Hospital Alemao Oswaldo Cruz | Sao Paulo | 01327 001 | Brazil | Details | ||
Fundacao Antonio Prudente A C Camargo Cancer Center | Sao Paulo | 01509 900 | Brazil | Details | ||
Onco Star SP Oncologia Ltda | Sao Paulo | 04543-000 | Brazil | Details | ||
IOS - Instituto de Oncologia de Sorocaba Dr. Gilson Delgado | Sorocaba | 18030-005 | Brazil | Details | ||
Hospital Nove de Julho | São Paulo | 01409902 | Brazil | Details | ||
COT - Centro Oncologico do Triangulo S.A | Uberlandia | 38408-150 | Brazil | Details | ||
Multifunctional Hospital for Active Treatment 'Serdika' | Sofia | 1303 | Bulgaria | Details | ||
Multiprofile Hospital for Active Treatment 'Tokuda Hospital Sofia' | Sofia | 1407 | Bulgaria | Details | ||
Specialized Hospital for Active Treatment in Oncology | Sofia | 1756 | Bulgaria | Details | ||
UMHAT Sofia Med | Sofia | 1797 | Bulgaria | Details | ||
Tom Baker Cancer Centre | Calgary | Alberta | T2N 4N2 | Canada | Details | |
British Columbia Cancer Agency | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
McGill University Health Centre | Montreal | Quebec | H4A 3J1 | Canada | Details | |
Cancer Hospital, Chinese Academy of Medical Sciences | Beijing | 100021 | China | Details | ||
Peking University People s Hospital | Beijing | 100044 | China | Details | ||
Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
Chinese PLA General Hospital | Beijing | 100853 | China | Details | ||
Beijing Chest hospital, Capital medical university | Beijing | 101199 | China | Details | ||
Hunan Cancer hospital | Changsha | 410013 | China | Details | ||
Sichuan Cancer Hospital | Chengdu | 610041 | China | Details | ||
West China Hospital Sichuan University | Chengdu | 610041 | China | Details | ||
Chongqing University Cancer Hospital | Chongqing | 400000 | China | Details | ||
Southwest Hospital | ChongQing | 400038 | China | Details | ||
The First Affiliated Hospital Sun Yat sen University | Guang Zhou | 510080 | China | Details | ||
Sun Yat-Sen Memorial Hospital Sun Yat-sen University | Guangzhou | 510120 | China | Details | ||
Zhejiang Cancer Hospital | Hang Zhou | 310022 | China | Details | ||
Second Affiliated Hospital, School of Medicine, Zhejiang University | Hangzhou | 310009 | China | Details | ||
The Second Affiliated Hospital of Zhejiang University College of Medicine | Hangzhou | 310009 | China | Details | ||
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine | Hangzhou | 310016 | China | Details | ||
Harbin medical university cancer hospital | Harbin | 150000 | China | Details | ||
Huizhou Municipal Central Hospital | Huizhou | 516001 | China | Details | ||
Taizhou Hospital of Zhejiang Province | Linhai | 317000 | China | Details | ||
Affiliated Hospital of North Sichuan Medical College | Nanchong | China | Details | |||
Ruijin Hospital Shanghai Jiao Tong University | Shanghai | 200025 | China | Details | ||
Fudan University Shanghai Cancer Center | Shanghai | 200032 | China | Details | ||
Shanghai East Hospital | Shanghai | 310000 | China | Details | ||
Shenzhen university General Hospital | Shenzhen | 518055 | China | Details | ||
Cancer Hospital Chinese Academy of Medical Sciences | Shenzhen | 518116 | China | Details | ||
Tianjin Medical University General Hospital | Tianjin | 300052 | China | Details | ||
Weifang People's Hospital | Weifang | 261000 | China | Details | ||
The First Affiliated Hospital of Xian Jiaotong University | XI An | 710061 | China | Details | ||
Yantai Yuhuangding Hospital | Yantai | 264000 | China | Details | ||
Daping Hospital Army Characteristic Medical Center | Yuzhong District | 400042 | China | Details | ||
Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
Fakultni nemocnice Olomouc - I.P.Pavlova 6 | Olomouc | 775 20 | Czechia | Details | ||
Vitkovicka nemocnice a.s. | Ostrava- Vitkovice | 70300 | Czechia | Details | ||
Fakultni nemocnice Plzen | Plzen | 30599 | Czechia | Details | ||
Rigshospitalet | Copenhagen | DK 2100 | Denmark | Details | ||
Institut Sainte Catherine | Avignon Cedex 9 | 84918 | France | Details | ||
Hospices Civils de Lyon HCL | Bron | 69500 | France | Details | ||
CHU de Grenoble Hopital Albert Michallon | La Tronche | 38700 | France | Details | ||
Centre Hospitalier du Mans | le Mans | 72000 | France | Details | ||
CHR Hôpital Calmette | Lille | 59000 | France | Details | ||
Hopital Nord | Marseille Cedex 20 | 13915 | France | Details | ||
CHU de Montpellier - Arnaud de Villeneuve | Montpellier Cedex 5 | 34295 | France | Details | ||
Institut Curie | Paris | 75005 | France | Details | ||
CHU Bordeaux | Pessac | 33604 | France | Details | ||
CHRU Hopital de Pontchaillou | Rennes | 35033 | France | Details | ||
CHU Nantes | Sain-Herblain | 44800 | France | Details | ||
Nouvel Hopital Civil - CHU Strasbourg | Strasbourg cedex | 67091 | France | Details | ||
CHU Bretonneau | Tours | 37000 | France | Details | ||
Evangelische Lungenklinik Berlin | Berlin | 13125 | Germany | Details | ||
Asklepios Klinikum Harburg | Hamburg | 21075 | Germany | Details | ||
Thoraxklinik am Universitatsklinikum Heidelberg | Heidelberg | 69126 | Germany | Details | ||
Onkologische Schwerpunktpraxis | Heilbronn | 74072 | Germany | Details | ||
POIS Sachsen GmbH iG | Leipzig | 04357 | Germany | Details | ||
Bethanien Krankenhaus | Moers | 47441 | Germany | Details | ||
Klinikum der Universitaet Muenchen | München | 80336 | Germany | Details | ||
Oncologianova GmbH | Recklinghausen | 45659 | Germany | Details | ||
Universitaetsklinikum Regensburg | Regensburg | 93053 | Germany | Details | ||
Queen Mary Hospital | Hong Kong | 999077 | Hong Kong | Details | ||
Health Care Global Enterprises pvt Ltd | Bangalore | 560027 | India | Details | ||
Artemis Hospital | Gurugram | 122001 | India | Details | ||
Tata Medical Center | Kolkata | 700160 | India | Details | ||
Tata Memorial Hospital | Mumbai | 400012 | India | Details | ||
HCG Manavta Cancer Centre | Nasik | 422002 | India | Details | ||
Rajiv Gandhi Cancer Institute and Research Centre | New Delh | 110085 | India | Details | ||
Noble Hospital Pvt Ltd | Pune | 411013 | India | Details | ||
Bhaktivedanta Hospital & Research Institute | Thane | 411107 | India | Details | ||
Soroka University Medical Center | Beersheba | 84101 | Israel | Details | ||
Rambam Health Corporation | Haifa | 3109601 | Israel | Details | ||
Shaare Zedek Medical Center | Jerusalem | 91031 | Israel | Details | ||
Meir Medical Center | Kfar Saba | 44281 | Israel | Details | ||
Rabin Medical Center | Petah Tikva | 49100 | Israel | Details | ||
Chaim Sheba Medical Center | Ramat Gan | 5262100 | Israel | Details | ||
Tel-Aviv Sourasky Medical Center | Tel-Aviv | 6423906 | Israel | Details | ||
CRO IRCCS Istituto Nazionale Tumori | Aviano | 33081 | Italy | Details | ||
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori | Meldola | 47014 | Italy | Details | ||
Istituto Europeo di Oncologia | Milano | 20141 | Italy | Details | ||
Azienda Ospedaliero-Universitaria Di Parma | Parma | 43126 | Italy | Details | ||
Ospedale S. Maria Delle Croci | Ravenna | 48121 | Italy | Details | ||
Istituto Nazionale Tumori Regina Elena | Roma | 00144 | Italy | Details | ||
Policlinico G.B.Rossi | Verona | 37134 | Italy | Details | ||
National Hospital Organization Shibukawa Medical Center | Gunma | 377-0280 | Japan | Details | ||
Hyogo Cancer Center | Hyogo | 673-8558 | Japan | Details | ||
Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
Kobe City Medical Center General Hospital | Kobe City | 650 0047 | Japan | Details | ||
Kurume University Hospital | Kurume | 830-0011 | Japan | Details | ||
National Hospital Organization Nagoya Medical Center | Nagoya-shi | 460-0001 | Japan | Details | ||
Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
Osaka International Cancer Institute | Osaka City | 541 8567 | Japan | Details | ||
Shizuoka Cancer Center | Shizuoka | 411 8777 | Japan | Details | ||
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital | Tokyo | 113 8677 | Japan | Details | ||
The Cancer Institute Hospital of JFCR | Tokyo | 135 8550 | Japan | Details | ||
Ehime University Hospital | Toon-shi | 791-0295 | Japan | Details | ||
Wakayama Medical University Hospital | Wakayama | 641 8510 | Japan | Details | ||
National Hospital Organization Iwakuni Clinical Center | Yamaguchi | 740-8510 | Japan | Details | ||
National Hospital Organization Yamaguchi Ube Medical Center | Yamaguchi | 755-0241 | Japan | Details | ||
National Cancer Center | Gyeonggi-do | 10408 | Korea, Republic of | Details | ||
CHA Bundang Medical Center, CHA University | Gyeonggi-do | 13496 | Korea, Republic of | Details | ||
Seoul National University Bundang Hospital | Gyeonggi-do | 13620 | Korea, Republic of | Details | ||
GyeongSang National University Hospital | Gyeongsangnam-do | 52727 | Korea, Republic of | Details | ||
Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
Severance Hospital Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
The Catholic University of Korea Seoul St Mary s Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
University Malaya Medical Centre | Kuala Lumpur | Malaysia | Details | |||
Hospital Tengku Ampuan Afzan | Kuantan | 25100 | Malaysia | Details | ||
Beacon Hospital Sdn Bhd | Petaling Jaya | 46050 | Malaysia | Details | ||
Subang Jaya Medical Centre | Subang Jaya | 47500 | Malaysia | Details | ||
Mount Miriam Cancer Hospital | Tanjung Bungah | 11200 | Malaysia | Details | ||
Hospital Civil de Guadalajara Fray Antonio Alcalde | Guadalajara | 44280 | Mexico | Details | ||
CIMOVA, Morals Vargas Centro de Investigación SC | Leon | 37000 | Mexico | Details | ||
Health Pharma Professional Research | Mexico | 03100 | Mexico | Details | ||
Instituto Nacional de Cancerologia | Mexico | 14080 | Mexico | Details | ||
Oncologia Integral Satelite | Naucalpan | 53100 | Mexico | Details | ||
VUMC Amsterdam | Amsterdam | 1081 HV | Netherlands | Details | ||
Ziekenhuis St Jansdal | Harderwijk | 3844 DG | Netherlands | Details | ||
Erasmus MC | Rotterdam | 3015 GD | Netherlands | Details | ||
Centrum Onkologii im. Prof. F. Lukaszczyka | Bydgoszcz | 85-796 | Poland | Details | ||
Uniwersyteckie Centrum Kliniczne | Gdansk | 80-952 | Poland | Details | ||
Szpitale Pomorskie Sp z o o | Gdynia | 81-519 | Poland | Details | ||
Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie | Olsztyn | 10-357 | Poland | Details | ||
Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandow | Poznan | 60 569 | Poland | Details | ||
Private Specialist Hospitals - MedPolonia | Poznan | 60-693 | Poland | Details | ||
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
Centro Hospitalar Lisboa Norte EPE - Hospital Pulido Valente | Lisboa | 1769-001 | Portugal | Details | ||
Hospital Beatriz Angelo | Loures | 2674 514 | Portugal | Details | ||
Centro Hospitalar Universitario do Porto, EPE | Porto | 4099-001 | Portugal | Details | ||
Instituto Portugues de Oncologia | Porto | 4200072 | Portugal | Details | ||
Pan American Center for Oncology Trials LLC | Rio Piedras | 00917 | Puerto Rico | Details | ||
City Clinical Hospital #1 | Nalchik | 360000 | Russian Federation | Details | ||
Llc, Eurocityclinic | Saint Petersburg | 197022 | Russian Federation | Details | ||
Hosp Univ A Coruna | A Coruña | 15006 | Spain | Details | ||
Hosp. de La Santa Creu I Sant Pau | Barcelona | 08025 | Spain | Details | ||
Hosp. Univ. Quiron Dexeus | Barcelona | 08028 | Spain | Details | ||
Hosp Univ Vall D Hebron | Barcelona | 08035 | Spain | Details | ||
Hosp Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
Hosp. Univ. Insular de Gran Canaria | Las Palmas de Gran Canaria | 35016 | Spain | Details | ||
Hosp. Gral. Univ. Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
Hosp Univ Fund Jimenez Diaz | Madrid | 28040 | Spain | Details | ||
Hosp. Univ. 12 de Octubre | Madrid | 28041 | Spain | Details | ||
Hosp. Univ. La Paz | Madrid | 28046 | Spain | Details | ||
Hosp Univ Hm Sanchinarro | Madrid | 28050 | Spain | Details | ||
Hosp. Univ. Pta. de Hierro Majadahonda | Majadahonda | 28222 | Spain | Details | ||
Hosp Regional Univ de Malaga | Málaga | 29010 | Spain | Details | ||
Clinica Univ. de Navarra | Pamplona | 31008 | Spain | Details | ||
Hosp. Virgen Del Rocio | Seville | 41013 | Spain | Details | ||
Hosp. Gral. Univ. Valencia | Valencia | 46014 | Spain | Details | ||
Hosp. Univ. I Politecni La Fe | Valencia | 46026 | Spain | Details | ||
Sahlgrenska Universitetssjukhuset | Goteborg | 413 45 | Sweden | Details | ||
Linkoping University Hospital | Linkoping | 581 85 | Sweden | Details | ||
Skanes universitetssjukhus | Lund | 221 85 | Sweden | Details | ||
Norrlands Universitetssjukhus | Umea | 901 85 | Sweden | Details | ||
Akademiska Sjukhuset | Uppsala | 75181 | Sweden | Details | ||
Changhua Christian Hospital | Changhua | 500 | Taiwan | Details | ||
Kaohsiung Medical University Chung Ho Memorial Hospital | Kaohsiung | 807 | Taiwan | Details | ||
Taipei Medical University Shuang Ho Hospital | New Taipei City | 23561 | Taiwan | Details | ||
Chung Shan Medical University Hospital | Taichung | 402 | Taiwan | Details | ||
Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
National Cheng Kung University Hospital | Tainan | 704 | Taiwan | Details | ||
National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
Adana City Hospital | Adana | 01060 | Turkey | Details | ||
Memorial Ankara Hastanesi | Ankara | 06520 | Turkey | Details | ||
Gazi University Hospital | Ankara | 06560 | Turkey | Details | ||
Ankara Bilkent City Hospital | Ankara | 06800 | Turkey | Details | ||
Trakya University Medical Faculty | Edirne | 22030 | Turkey | Details | ||
Istanbul University Cerrahpasa Medical Faculty | Istanbul | 34098 | Turkey | Details | ||
Bakirkoy Training and Research Hospital | Istanbul | 34147 | Turkey | Details | ||
Medipol Mega University Hospital | Istanbul | 34214 | Turkey | Details | ||
Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi | Istanbul | 34722 | Turkey | Details | ||
Medical Point | Izmir | 35575 | Turkey | Details | ||
Velindre Hospital | Cardiff | CF14 2TL | United Kingdom | Details | ||
Edinburgh Cancer Centre Western General | Edinburgh | EH4 2XU | United Kingdom | Details | ||
UCL Cancer Institute | London | NW1 2PG | United Kingdom | Details | ||
Guys and St Thomas NHS Foundation Trust | London | SE1 9RT | United Kingdom | Details | ||
The Royal Marsden NHS Trust | London | SW3 6JJ | United Kingdom | Details | ||
The Christie Nhs Foundation Trust | Manchester | M20 4BX | United Kingdom | Details |