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| NCT ID | NCT05064059 |
| Title | A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | NOR | ITA | ISR | GBR | FRA | ESP | DEU | CZE | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Georgetown University Hospital ( Site 1148) | Washington | District of Columbia | 20007 | United States | Details | |
| Sibley Memorial Hospital ( Site 1143) | Washington | District of Columbia | 20016 | United States | Details | |
| Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 1118) | Marietta | Georgia | 30060 | United States | Details | |
| Norton Cancer Institute ( Site 1139) | Louisville | Kentucky | 40217 | United States | Details | |
| Rutgers Cancer Institute of New Jersey ( Site 1105) | New Brunswick | New Jersey | 08903 | United States | Details | |
| Memorial Sloan Kettering Cancer Center ( Site 1703) | New York | New York | 10065 | United States | Details | |
| Oregon Health & Science University ( Site 1141) | Portland | Oregon | 97239 | United States | Details | |
| MUSC Hollings Cancer Center ( Site 1715) | Charleston | South Carolina | 29425 | United States | Details | |
| The West Clinic, PLLC dba West Cancer Center ( Site 1149) | Germantown | Tennessee | 38138 | United States | Details | |
| UT Southwestern Medical Center ( Site 1709) | Dallas | Texas | 75390-9063 | United States | Details | |
| Intermountain Medical Center ( Site 1707) | Murray | Utah | 84107 | United States | Details | |
| Inova Schar Cancer Institute ( Site 1130) | Fairfax | Virginia | 22031 | United States | Details | |
| VCU Health Adult Outpatient Pavillion ( Site 1712) | Richmond | Virginia | 23219 | United States | Details | |
| Blue Ridge Cancer Care ( Site 1718) | Roanoke | Virginia | 24014 | United States | Details | |
| Seattle Cancer Care Alliance ( Site 1107) | Seattle | Washington | 98109 | United States | Details | |
| Westmead Hospital ( Site 0057) | Westmead | New South Wales | 2145 | Australia | Details | |
| Royal Brisbane and Women s Hospital ( Site 0058) | Herston | Queensland | 4029 | Australia | Details | |
| Queen Elizabeth Hospital ( Site 0050) | Woodville South | South Australia | 5011 | Australia | Details | |
| Frankston Hospital ( Site 0056) | Frankston | Victoria | 3199 | Australia | Details | |
| Western Health-Sunshine & Footscray Hospitals ( Site 0052) | St Albans | Victoria | 3021 | Australia | Details | |
| St John of God Subiaco Hospital ( Site 0051) | Perth | Western Australia | 6008 | Australia | Details | |
| London Regional Cancer Program - London HSC ( Site 0154) | London | Ontario | N6A 5W9 | Canada | Details | |
| The Ottawa Hospital ( Site 0151) | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Princess Margaret Cancer Centre-Division of Medical Oncology and Hematology ( Site 0155) | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Centro Investigacion Cancer James Lind ( Site 0204) | Temuco | Araucania | 4800827 | Chile | Details | |
| IC La Serena Research ( Site 0202) | La Serena | Coquimbo | 1720430 | Chile | Details | |
| Clinica Puerto Montt ( Site 0211) | Puerto Montt | Los Lagos | 5500656 | Chile | Details | |
| Fundacion Arturo Lopez Perez FALP ( Site 0208) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
| Oncovida ( Site 0209) | Santiago | Region M. De Santiago | 7510032 | Chile | Details | |
| Clínica Vespucio ( Site 0205) | Santiago | Region M. De Santiago | 8241479 | Chile | Details | |
| Pontificia Universidad Catolica de Chile ( Site 0206) | Santiago | Region M. De Santiago | 8330032 | Chile | Details | |
| Bradfordhill ( Site 0200) | Santiago | Region M. De Santiago | 8420383 | Chile | Details | |
| The Second Affiliated Hospital of Anhui Medical University ( Site 1179) | Hefei | Anhui | 230601 | China | Details | |
| Chongqing Cancer Hospital ( Site 1151) | Chongqing | Chongqing | 400030 | China | Details | |
| Fujian Province Cancer Hospital ( Site 1178) | Fuzhou | Fujian | 350014 | China | Details | |
| Sun Yat-Sen University Cancer Center ( Site 1150) | Guangzhou | Guangdong | 510060 | China | Details | |
| Southern Medical University Nanfang Hospital ( Site 1154) | Guangzhou | Guangdong | 510515 | China | Details | |
| The Sixth Affiliated Hospital of Sun Yat-sen University ( Site 1159) | Guangzhou | Guangdong | 510655 | China | Details | |
| Guangxi Medical University Affiliated Tumor Hospital ( Site 1158) | Nanning | Guangxi | 531021 | China | Details | |
| Hainan General Hospital ( Site 1177) | Haikou | Hainan | 570311 | China | Details | |
| Wuhan Union Hospital Cancer Center ( Site 1162) | Wuhan | Hubei | 430022 | China | Details | |
| Hubei Cancer Hospital ( Site 1152) | Wuhan | Hubei | 430079 | China | Details | |
| Xiangya Hospital Central South University ( Site 1171) | Changsha | Hunan | 410008 | China | Details | |
| Hunan Cancer Hospital ( Site 1174) | Changsha | Hunan | 410013 | China | Details | |
| The Third Xiangya Hospital of Central South University ( Site 1175) | Changsha | Hunan | 410013 | China | Details | |
| Changzhou Cancer Hospital-Department of Oncology ( Site 1183) | Changzhou | Jiangsu | 213000 | China | Details | |
| Affiliated Hospital of Jiangnan University(Wuxi Fourth People's Hospital ) ( Site 1185) | Wuxi City | Jiangsu | 214122 | China | Details | |
| Jilin Cancer Hospital ( Site 1163) | Changchun | Jilin | 130012 | China | Details | |
| Jinan Central Hospital ( Site 1167) | Jinan | Shandong | 250000 | China | Details | |
| Fudan University Shanghai Cancer Center ( Site 1176) | Shangai | Shanghai | 201321 | China | Details | |
| Shanghai Tenth People's Hospital ( Site 1170) | Shanghai | Shanghai | 200072 | China | Details | |
| West China Hospital Sichuan University ( Site 1172) | Chengdu | Sichuan | 332001 | China | Details | |
| Tianjin Medical University Cancer Institute and Hospital ( Site 1161) | Tianjin | Tianjin | 300060 | China | Details | |
| Yunnan Province Cancer Hospital-Colorectal surgery ( Site 1169) | Kunming | Yunnan | 650106 | China | Details | |
| Zhejiang Cancer Hospital ( Site 1180) | Hangzhou | Zhejiang | 310005 | China | Details | |
| Sir Run Run Shaw Hospital-Medical Oncology ( Site 1173) | Hangzhou | Zhejiang | 310018 | China | Details | |
| Masarykuv onkologicky ustav ( Site 1203) | Brno | Brno-mesto | 656 53 | Czechia | Details | |
| Fakultni nemocnice v Motole ( Site 1201) | Praha | Praha, Hlavni Mesto | 150 06 | Czechia | Details | |
| Fakultni nemocnice Hradec Kralove ( Site 1207) | Hradec Kralove | 500 05 | Czechia | Details | ||
| Fakultni nemocnice Olomouc ( Site 1204) | Olomouc | 779 00 | Czechia | Details | ||
| Fakultni nemocnice Kralovske Vinohrady ( Site 1208) | Praha 10 | 100 34 | Czechia | Details | ||
| Fakultni Thomayerova nemocnice ( Site 1205) | Praha 4 | 140 59 | Czechia | Details | ||
| Fakultni nemocnice Na Bulovce ( Site 1202) | Praha 8 | 180 81 | Czechia | Details | ||
| CHU Bordeaux Haut-Leveque ( Site 0305) | Pessac | Gironde | 33604 | France | Details | |
| CHU Hotel Dieu Nantes ( Site 0303) | Nantes | Pays-de-la-Loire | 44093 | France | Details | |
| Institut du Cancer Avignon-Provence ( Site 0306) | Avignon | Vaucluse | 84000 | France | Details | |
| CHU Poitiers ( Site 0304) | Poitiers | Vienne | 86021 | France | Details | |
| Hopital Europeen Georges Pompidou ( Site 0300) | Paris | 75015 | France | Details | ||
| LMU Klinikum Grosshadern der Universitaet Muenchen ( Site 1253) | Muenchen | Bayern | 81377 | Germany | Details | |
| Philipps-Universitaet Marburg. ( Site 1252) | Marburg | Hessen | 35043 | Germany | Details | |
| Klinikum Wolfsburg ( Site 1256) | Wolfsburg | Niedersachsen | 38440 | Germany | Details | |
| Johanniter Krankenhaus Bonn ( Site 1254) | Bonn | Nordrhein-Westfalen | 53113 | Germany | Details | |
| Kliniken Maria Hilf GmbH ( Site 1255) | Moenchengladbach | Nordrhein-Westfalen | 41063 | Germany | Details | |
| Universitätsklinikum Halle ( Site 1251) | Halle (Saale) | Sachsen-Anhalt | 06120 | Germany | Details | |
| Katholisches Marienkrankenhaus gGmbH ( Site 1257) | Hamburg | 22087 | Germany | Details | ||
| Assuta Ashdod Public ( Site 0507) | Ashdod | 7747629 | Israel | Details | ||
| Rambam Health Care Campus-Oncology Division ( Site 0500) | Haifa | 3109601 | Israel | Details | ||
| Bnei Zion Medical Center ( Site 0506) | Haifa | 3339419 | Israel | Details | ||
| Hadassa Ein Karem Medical Center ( Site 0504) | Jerusalem | 9112001 | Israel | Details | ||
| Rabin Medical Center ( Site 0503) | Petah Tikva | 4941492 | Israel | Details | ||
| Chaim Sheba Medical Center ( Site 0501) | Ramat Gan | 5262000 | Israel | Details | ||
| Sourasky Medical Center ( Site 0502) | Tel Aviv | 6423906 | Israel | Details | ||
| Policlinico Gemelli di Roma ( Site 0552) | Roma | Abruzzo | 00168 | Italy | Details | |
| IRCCS Casa Sollievo della Sofferenza ( Site 0554) | San Giovanni Rotondo | Foggia | 71013 | Italy | Details | |
| Istituto Clinico Humanitas - Cancer Center ( Site 0555) | Rozzano | Milano | 20089 | Italy | Details | |
| A.O. di Rilievo Nazionale e di alta Specializzazione Garibaldi ( Site 0553) | Catania | 95122 | Italy | Details | ||
| ASST Grande Ospedale Metropolitano Niguarda ( Site 0550) | Milano | 20162 | Italy | Details | ||
| Universita degli Studi della Campania Luigi Vanvitelli-UOC Oncoematologia ( Site 0556) | Napoli | 80131 | Italy | Details | ||
| National Cancer Center Hospital East ( Site 0600) | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| Kagawa University Hospital ( Site 0608) | Kita-gun | Kagawa | 761-0793 | Japan | Details | |
| Kindai University Hospital ( Site 0607) | Osakasayama | Osaka | 5898511 | Japan | Details | |
| Saitama Prefectural Cancer Center ( Site 0603) | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details | |
| Shizuoka Cancer Center ( Site 0605) | Sunto-gun, | Shizuoka | 411-8777 | Japan | Details | |
| National Hospital Organization Kyushu Cancer Center ( Site 0609) | Fukuoka | 811-1395 | Japan | Details | ||
| National Cancer Center Hospital ( Site 0601) | Tokyo | 104-0045 | Japan | Details | ||
| Japanese Foundation for Cancer Research ( Site 0602) | Tokyo | 135-8550 | Japan | Details | ||
| Asan Medical Center ( Site 0650) | Songpagu | Seoul | 05505 | Korea, Republic of | Details | |
| Seoul National University Hospital ( Site 0653) | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital ( Site 0652) | Seoul | 03722 | Korea, Republic of | Details | ||
| Samsung Medical Center ( Site 0651) | Seoul | 06351 | Korea, Republic of | Details | ||
| Pantai Hospital Kuala Lumpur ( Site 1303) | Bangsar | Kuala Lumpur | 59100 | Malaysia | Details | |
| Beacon Hospital Sdn Bhd ( Site 1305) | Petaling Jaya | Selangor | 46050 | Malaysia | Details | |
| Institut Kanser Negara - National Cancer Institute ( Site 1302) | Putrajaya | Wilayah Persekutuan Putrajaya | 62250 | Malaysia | Details | |
| University Malaya Medical Centre ( Site 1301) | Kuala Lumpur | 59100 | Malaysia | Details | ||
| Akershus universitetssykehus ( Site 1352) | Loerenskog | Akershus | 1478 | Norway | Details | |
| St Olavs Hospital ( Site 1354) | Trondheim | Sor-Trondelag | 7030 | Norway | Details | |
| Universitetssykehuset i Nord Norge. ( Site 1355) | Tromsoe | Troms | 9019 | Norway | Details | |
| Helse Bergen HF - Haukeland univeritetssykehus ( Site 1353) | Bergen | Vestfold | 5053 | Norway | Details | |
| Oslo Universitetssykehus HF. Ulleval ( Site 1351) | Oslo | 0450 | Norway | Details | ||
| Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 0871) | Ufa | Baskortostan, Respublika | 450054 | Russian Federation | Details | |
| SRBHI of Kirov Region Center of Oncology and medical radiology ( Site 0854) | Kirov | Kirovskaya Oblast | 105094 | Russian Federation | Details | |
| Main Military Clinical Hospital n.a. N.N.Burdenko ( Site 0870) | Moscow | Moskva | 105094 | Russian Federation | Details | |
| FSBI-FRCC of Special Types Med. Care and Technologies FMBA of Russia ( Site 0851) | Moscow | Moskva | 115682 | Russian Federation | Details | |
| City Hospital #40 ( Site 0853) | Saint Petersburg | Sankt-Peterburg | 197706 | Russian Federation | Details | |
| Clinical Research Center of specialized types medical care-Oncology ( Site 0860) | Saint-Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details | |
| Tomsk National Research Medical Center of Russian Academy of Sciences ( Site 0872) | Tomsk | Tomskaya Oblast | 634045 | Russian Federation | Details | |
| Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 0850) | Yaroslavl | Yaroslavskaya Oblast | 150054 | Russian Federation | Details | |
| SHBI "Leningrad Regional Clinical Oncology Dispensary n.a. L.D. Roman"-Clinical Trials Department ( | Sankt-Peterburg | 188663 | Russian Federation | Details | ||
| Cancer Care Langenhoven Drive Oncology Centre ( Site 1504) | Port Elizabeth | Eastern Cape | 6045 | South Africa | Details | |
| Sandton Oncology Medical Group PTY LTD ( Site 1501) | Sandton | Gauteng | 2196 | South Africa | Details | |
| Cape Town Oncology Trials Pty Ltd ( Site 1506) | Kraaifontein | Western Cape | 7570 | South Africa | Details | |
| Cancercare Rondebosch Oncology ( Site 1509) | Rondebosch | Western Cape | 7700 | South Africa | Details | |
| Hospital Universitari Vall d Hebron ( Site 0900) | Barcelona | 08035 | Spain | Details | ||
| Hospital Sant Pau i la Santa Creu ( Site 0905) | Barcelona | 08041 | Spain | Details | ||
| Hospital Clinico San Carlos ( Site 0902) | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre ( Site 0901) | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario Virgen Macarena ( Site 0906) | Sevilla | 41009 | Spain | Details | ||
| Chang Gung Medical Foundation - Kaohsiung ( Site 0956) | Kaohsiung | Changhua | 833 | Taiwan | Details | |
| China Medical University Hospital ( Site 0953) | Taichung | 40447 | Taiwan | Details | ||
| National Cheng Kung University Hospital ( Site 0955) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital ( Site 0950) | Taipei | 10048 | Taiwan | Details | ||
| Taipei Veterans General Hospital ( Site 0951) | Taipei | 11217 | Taiwan | Details | ||
| Chang Gung Medical Foundation. Linkou ( Site 0952) | Taoyuan | 333 | Taiwan | Details | ||
| Baskent Universitesi Dr. Turgut Noyan Uygulama ve Arastirma Merkezi ( Site 1007) | Adana | 01120 | Turkey | Details | ||
| Acibadem Adana Hastanesi ( Site 1008) | Adana | 01130 | Turkey | Details | ||
| Gulhane Egitim ve Arastirma Hastanesi ( Site 1009) | Ankara | 06010 | Turkey | Details | ||
| Hacettepe Universitesi Tip Fakultesi ( Site 1003) | Ankara | 06230 | Turkey | Details | ||
| Ankara Sehir Hastanesi ( Site 1005) | Ankara | 06800 | Turkey | Details | ||
| Antalya Egitim ve Arastirma Hastanesi ( Site 1010) | Antalya | 07100 | Turkey | Details | ||
| Goztepe Prof.Dr. Suleyman Yalcin Sehir Hastanesi ( Site 1002) | Istanbul | 34722 | Turkey | Details | ||
| Ege Universitesi Tip Fakultesi Hastanesi ( Site 1006) | Izmir | 35100 | Turkey | Details | ||
| Municipal Non-Profit Enterprise City Clinical Hospital 4 of Dnipro City Council ( Site 1657) | Dnipro | Dnipropetrovska Oblast | 49102 | Ukraine | Details | |
| MI Precarpathian Clinical Oncology Center ( Site 1654) | Ivano-Frankivsk | Ivano-Frankivska Oblast | 76018 | Ukraine | Details | |
| Ukrainian Center of Tomotherapy ( Site 1658) | Kropyvnytskyi | Kirovohradska Oblast | 25011 | Ukraine | Details | |
| Odessa Regional Clinical Hospital ( Site 1664) | Odesa | Odeska Oblast | 65025 | Ukraine | Details | |
| University College London Hospitals NHS Foundation Trust ( Site 1056) | London | Camden | WC1E 6AG | United Kingdom | Details | |
| Royal Marsden NHS Foundation Trust ( Site 1064) | London | London, City Of | SW3 6JJ | United Kingdom | Details | |
| Imperial College Healthcare NHS Trust - Hammersmith Hospital ( Site 1052) | London | London, City Of | W12 0HS | United Kingdom | Details | |
| Royal Marsden NHS Trust ( Site 1063) | Sutton | London, City Of | SM25PT | United Kingdom | Details | |
| University Hospital Coventry & Warwickshire ( Site 1062) | Coventry | Warwickshire | CV2 2DX | United Kingdom | Details | |
| Velindre Cancer Centre ( Site 1058) | Cardiff | United Kingdom | Details | |||
| Leeds Teaching Hospitals NHS Trust ( Site 1050) | Leeds | LS9 7TF | United Kingdom | Details |