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| NCT ID | NCT05198934 |
| Title | Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation (CodeBreak300) |
| Acronym | CodeBreak300 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Amgen |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | GRC | GBR | FRA | ESP | DEU | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Central Alabama Research | Birmingham | Alabama | 35209 | United States | Details | |
| City of Hope National Medical Center | Duarte | California | 91010 | United States | Details | |
| University of California Irvine | Orange | California | 92868 | United States | Details | |
| Johns Hopkins University School of Medicine | Washington | District of Columbia | 20016 | United States | Details | |
| Cancer Specialists of North Florida | Jacksonville | Florida | 32256 | United States | Details | |
| Lakes Research LLC | Miami Lakes | Florida | 33014 | United States | Details | |
| Northwest Georgia Oncology Centers PC | Marietta | Georgia | 30060 | United States | Details | |
| University of Michigan | Ann Arbor | Michigan | 48106-0995 | United States | Details | |
| Revive Research Institute | Farmington Hills | Michigan | 48334 | United States | Details | |
| Sparrow Clinical Research Institute | Lansing | Michigan | 48912 | United States | Details | |
| Revive Research Institute | Sterling Heights | Michigan | 48314 | United States | Details | |
| Upstate University Hospital | Syracuse | New York | 13210 | United States | Details | |
| White Plains Hospital Center for Cancer Care | White Plains | New York | 10601 | United States | Details | |
| Moses H Cone Memorial Hospital | Greensboro | North Carolina | 27403 | United States | Details | |
| The Mark H Zangmeister Center | Columbus | Ohio | 43210 | United States | Details | |
| Lancaster General Hospital Ann B Barshinger Cancer Institute | Lancaster | Pennsylvania | 17601 | United States | Details | |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Kelsey Research Foundation | Houston | Texas | 77025 | United States | Details | |
| Best Cancer Care & Hematology | Houston | Texas | 77089 | United States | Details | |
| Lumi Research | Kingwood | Texas | 77339 | United States | Details | |
| Chris OBrien Lifehouse | Camperdown | New South Wales | 2050 | Australia | Details | |
| GenesisCare -North Shore (Oncology) | St Leonards | New South Wales | 2065 | Australia | Details | |
| Westmead Hospital | Westmead | New South Wales | 2145 | Australia | Details | |
| The Queen Elizabeth Hospital | Woodville South | South Australia | 5011 | Australia | Details | |
| Centre Hospitalier Universitaire de Lyon - Hopital Edouard Herriot | Lyon Cédex 3 | 69437 | France | Details | ||
| Institut regional du Cancer Montpellier | Montpellier Cedex 5 | 34298 | France | Details | ||
| Hôpital Européen Georges Pompidou | Paris | 75015 | France | Details | ||
| Hôpital Haut -lévêque | Pessac | 33604 | France | Details | ||
| Charite Universitaetsmedizin Berlin, Charité Campus Virchow-Klinikum | Berlin | 13353 | Germany | Details | ||
| Universitaetsklinikum Carl Gustav Carus an der Technischen Universitaet Dresden | Dresden | 01307 | Germany | Details | ||
| Universitaetsmedizin Goettingen - Georg-August-Universitaet | Goettingen | 37075 | Germany | Details | ||
| Klinikum der Universitaet Muenchen Campus Grosshadern | Muenchen | 81377 | Germany | Details | ||
| Universitaetsklinikum der Eberhard Karls Universitaet Tuebingen | Tuebingen | 72076 | Germany | Details | ||
| General Hospital of Athens Laiko | Athens | 11527 | Greece | Details | ||
| Evgenidio Hospital I Agia Trias | Athens | 11528 | Greece | Details | ||
| Hygeia Hospital | Athens | 15123 | Greece | Details | ||
| University Hospital of Heraklion | Heraklion - Crete | 71500 | Greece | Details | ||
| University Hospital of Patras | Patra | 26504 | Greece | Details | ||
| Theagenion Anticancer Hospital | Thessaloniki | 54007 | Greece | Details | ||
| Agios Loukas Clinic | Thessaloniki | 55236 | Greece | Details | ||
| Istituto Ospedaliero Fondazione Poliambulanza | Brescia | 25124 | Italy | Details | ||
| Azienda Ospedaliera Rilievo Nazionale e Alta Specializzazione Garibaldi Nesima | Catania | 95122 | Italy | Details | ||
| Azienda Ospedaliera Santa Croce e Carle | Confreria (CN) | 12100 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Careggi | Firenze | 50134 | Italy | Details | ||
| Ospedale Policlinico San Martino IRCCS | Genova | 16132 | Italy | Details | ||
| Azienda Sanitaria Locale 5 Spezzino Ospedale S Andrea | La Spezia | 19100 | Italy | Details | ||
| Azienda Unita Sanitaria Locale LE Presidio Ospedaliero Vito Fazzi Polo Oncologico Giovanni Paolo II | Lecce | 73100 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | 20133 | Italy | Details | ||
| Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda | Milano | 20162 | Italy | Details | ||
| Azienda Ospedaliero Universitaria di Cagliari Policlinico Duilio Casula | Monserrato CA | 09042 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Luigi Vanvitelli | Napoli | 80131 | Italy | Details | ||
| Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Maggiore della Carita | Novara | 28100 | Italy | Details | ||
| Istituto Oncologico Veneto IRCCS | Padova | 35128 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Pisana Ospedale Santa Chiara | Pisa | 56126 | Italy | Details | ||
| Azienda Ospedaliera San Carlo | Potenza | 85100 | Italy | Details | ||
| Azienda Unita Sanitaria Locale di Reggio Emilia Arcispedale Santa Maria Nuova | Reggio Emilia | 42100 | Italy | Details | ||
| Fondazione Policlinico Tor Vergata | Roma (RM) | 00133 | Italy | Details | ||
| Policlinico Universitario Agostino Gemelli | Roma | 00168 | Italy | Details | ||
| Azienda Ospedaliera San Giovanni Addolorata | Roma | 00184 | Italy | Details | ||
| Azienda Ospedaliera Cardinale Giovanni Panico | Tricase | 73039 | Italy | Details | ||
| Azienda Unita Locale Socio Sanitaria Berica 8 | Vicenza | 36100 | Italy | Details | ||
| Aichi Medical University Hospital | Nagakute-shi | Aichi | 480-1195 | Japan | Details | |
| Chiba Cancer Center | Chiba-shi | Chiba | 260-8717 | Japan | Details | |
| National Cancer Center Hospital East | Kashiwa-shi | Chiba | 277-8577 | Japan | Details | |
| National Hospital Organization Shikoku Cancer Center | Matsuyama-shi | Ehime | 791-0280 | Japan | Details | |
| National Hospital Organization Kyushu Cancer Center | Fukuoka-shi | Fukuoka | 811-1395 | Japan | Details | |
| Hokkaido University Hospital | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| Hyogo Cancer Center | Akashi-shi | Hyogo | 673-8558 | Japan | Details | |
| St Marianna University Hospital | Kawasaki-shi | Kanagawa | 216-8511 | Japan | Details | |
| Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center | Yokohama-shi | Kanagawa | 241-8515 | Japan | Details | |
| National Hospital Organization Osaka National Hospital | Osaka-shi | Osaka | 540-0006 | Japan | Details | |
| Osaka University Hospital | Suita-shi | Osaka | 565-0871 | Japan | Details | |
| Saitama Cancer Center | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details | |
| Shizuoka Cancer Center | Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| National Cancer Center Hospital | Chuo-ku | Tokyo | 104-0045 | Japan | Details | |
| The Cancer Institute Hospital of Japanese Foundation for Cancer Research | Koto-ku | Tokyo | 135-8550 | Japan | Details | |
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Superare Centro de Infusion SA de CV | Ciudad de Mexico | Distrito Federal | 06760 | Mexico | Details | |
| Health Pharma Professional Research SA de CV | Mexico City | Distrito Federal | 03100 | Mexico | Details | |
| Trials In Medicine SC | Ciudad de Mexico | 06700 | Mexico | Details | ||
| Hospital Universitario Reina Sofia | Cordoba | Andalucía | 14004 | Spain | Details | |
| Hospital Universitario Virgen de las Nieves | Granada | Andalucía | 18014 | Spain | Details | |
| Hospital Universitario Marques de Valdecilla | Santander | Cantabria | 39008 | Spain | Details | |
| Hospital Universitari Vall d Hebron | Barcelona | Cataluña | 08035 | Spain | Details | |
| Hospital de la Santa Creu i Sant Pau | Barcelona | Cataluña | 08041 | Spain | Details | |
| Hospital General Universitario de Elche | Elche | Comunidad Valenciana | 03203 | Spain | Details | |
| Hospital General Universitario de Valencia | Valencia | Comunidad Valenciana | 46014 | Spain | Details | |
| Complexo Hospitalario Universitario de Ourense | Ourense | Galicia | 32005 | Spain | Details | |
| Hospital Universitario de Navarra | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung | 80756 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 70403 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation | Taoyuan | 33305 | Taiwan | Details | ||
| Beatson West of Scotland Cancer Centre | Glasgow | G12 0YN | United Kingdom | Details | ||
| Royal Free Hospital | London | NW3 2QG | United Kingdom | Details | ||
| Royal Marsden Hospital | London | SW3 6JJ | United Kingdom | Details | ||
| Maidstone Hospital | Maidstone | ME16 9QQ | United Kingdom | Details | ||
| Mount Vernon Cancer Centre | Northwood | HA6 2RN | United Kingdom | Details | ||
| Royal Marsden Hospital | Sutton | SM2 5PT | United Kingdom | Details |