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NCT ID NCT05215340
Title Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations (TROPION-Lung08)
Acronym TROPION-Lung08
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Daiichi Sankyo, Inc.
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | TUR | ROU | POL | NLD | ITA | HUN | GRC | GBR | FRA | ESP | DEU | CHE | CAN | BRA | BEL | AUT | AUS | ARG

Facility Status City State Zip Country Details
Ironwood Cancer and Research Center RECRUITING Chandler Arizona 85224 United States Details
UCLA HemOnc - Clinical Research Unit RECRUITING Los Angeles California 90095 United States Details
Compassionate Cancer Care Medical Group RECRUITING Riverside California 92501 United States Details
UCSF Helen Diller Family Comprehensive Cancer Center RECRUITING San Francisco California 94158 United States Details
Ridley-Tree Cancer Center RECRUITING Santa Barbara California 93105 United States Details
PIH Health Whittier Hospital RECRUITING Whittier California 90602 United States Details
The Oncology Institute of Hope and Innovation RECRUITING Whittier California 90603 United States Details
Uch-Mhs D/B/A Memorial Health System RECRUITING Colorado Springs Colorado 80909 United States Details
Johns Hopkins University RECRUITING Baltimore Maryland 21205 United States Details
American Oncology Partners of Maryland RECRUITING Bethesda Maryland 20817 United States Details
Dana-Farber Cancer Institute RECRUITING Boston Massachusetts 02115 United States Details
Beth Israel Deaconess Medical Center RECRUITING Boston Massachusetts 02215 United States Details
DFCI - Steward St. Elizabeth's Medical Center RECRUITING Boston Massachusetts 02215 United States Details
Dana Farber Cancer Institute - Foxborough RECRUITING Foxboro Massachusetts 02035 United States Details
Dana Farber Cancer Institute - Milford Medical Center RECRUITING Milford Massachusetts 01757 United States Details
DFCI - South Shore Hospital RECRUITING South Weymouth Massachusetts 02190 United States Details
Dartmouth Hitchcock Medical Center RECRUITING Lebanon New Hampshire 03766 United States Details
Astera Cancer Care RECRUITING East Brunswick New Jersey 08816 United States Details
Regional Cancer Care Associates LLC RECRUITING Freehold New Jersey 07728 United States Details
Cooperman Barnabas Medical Center RECRUITING New Brunswick New Jersey 08901 United States Details
The Valley Hospital RECRUITING Paramus New Jersey 07652 United States Details
Montefiore Medical Center RECRUITING Bronx New York 10461 United States Details
Arizona Oncology NAHOA RECRUITING Irving Texas 75063 United States Details
Cancer Care Center of Brevard RECRUITING Irving Texas 75063 United States Details
Illinois Cancer Specialists RECRUITING Irving Texas 75063 United States Details
Maryland Oncology Hematology RECRUITING Irving Texas 75063 United States Details
Southern Cancer Center RECRUITING Irving Texas 75063 United States Details
Texas Oncology - Northeast Texas RECRUITING Irving Texas 75063 United States Details
Texas Oncology Gulf Coast RECRUITING Irving Texas 75063 United States Details
Texas Oncology McAllen RECRUITING Irving Texas 75063 United States Details
Woodlands Medical RECRUITING Irving Texas 75063 United States Details
University of Texas Health Science Center San Antonio RECRUITING San Antonio Texas 78229 United States Details
Utah Cancer Specialists RECRUITING Salt Lake City Utah 84106 United States Details
Providence Regional Cancer System RECRUITING Lacey Washington 98503 United States Details
VA Puget Sound Health Care System - VAPSHCS RECRUITING Seattle Washington 98108 United States Details
Medical College of Wisconsin RECRUITING Milwaukee Wisconsin 53226 United States Details
Fundacion CENIT para la investigación en Neurociencias RECRUITING Ciudad Autonoma de Buenos Aire 1125 Argentina Details
Hospital Privado de la Comunidad RECRUITING Mar del Plata B7602CBM Argentina Details
Centro de Investigación Pergamino S. A. RECRUITING Pergamino 2700 Argentina Details
Instituto de Oncología de Rosario RECRUITING Rosario S2000 Argentina Details
Sanatorio Parque RECRUITING Rosario S2001 Argentina Details
Sanatorio Británico de Rosario RECRUITING Rosario S2002 Argentina Details
CER SAN JUAN - Centro Polivalente de Asistencia e Investigación Clínica RECRUITING San Juan 5400 Argentina Details
Clinica Viedma SA RECRUITING Viedma 8500 Argentina Details
Austin Hospital RECRUITING Heidelberg Victoria 3084 Australia Details
Peninsula and South Eastern Haematology and Oncology Group RECRUITING Mount Waverley Victoria 3149 Australia Details
Chris Obrien Lifehouse RECRUITING Camperdown 2050 Australia Details
The Queen Elizabeth Hospital RECRUITING Woodville South 5011 Australia Details
Klinikum Klagenfurt am Wörthersee Abteilung für Lungenkrankheiten RECRUITING Klagenfurt Austria Details
Karl-Landsteiner Institute for Lung Research and Pulmonary Oncology c/o Klinik Floridsdorf RECRUITING Vienna 1090 Austria Details
Onze-Lieve-Vrouwziekenhuis Olvz - Campus Aalst RECRUITING Aalst 9300 Belgium Details
Grand Hopital de Charleroi - Hopital Saint Joseph RECRUITING Charleroi 6000 Belgium Details
Az Maria Middelares - Campus Maria Middelares RECRUITING Gent 9000 Belgium Details
AZ Nikolaas RECRUITING Sint-Niklaas 9100 Belgium Details
Instituto de Pesquisas em Saúde - IPS RECRUITING Caxias Do Sul 95020-972 Brazil Details
Hospital Erasto Gaertner RECRUITING Curitiba 81520-060 Brazil Details
Oncosite - Centro de Pesquisa Clinica Oncologia RECRUITING Ijui 98700-000 Brazil Details
Clínica de Neoplasias Litoral RECRUITING Itajaí 88301-220 Brazil Details
UPCO - Unidade de Pesquisas Clínicas em Oncologia - Clinica Lacks RECRUITING Pelotas 96020-080 Brazil Details
Santa Casa de Misericordia de Porto Alegre RECRUITING Porto Alegre 90050-170 Brazil Details
Instituto Nacional de Câncer - INCA RECRUITING Rio De Janeiro 20231-050 Brazil Details
Centro de Estudos e Pesquisa de Hematologia e Oncologia - CEPHO RECRUITING Santo Andre 09060-870 Brazil Details
Instituto de Ensino e Pesquisas Sao Lucas RECRUITING Sao Paulo 01236-030 Brazil Details
Instituto do Cancer Brasil - Unidade Taubate RECRUITING Taubate Brazil Details
McGill University Health Centre RECRUITING Montreal H4A 3J2 Canada Details
Santa Cabrini Hospital RECRUITING Montréal H1T 2M4 Canada Details
Centro de Estudios Clínicos SAGA RECRUITING Santiago de Chile Metropolitana 7500653 Chile Details
Oncovida RECRUITING Santiago 7500000 Chile Details
Fundación Arturo Pérez López RECRUITING Santiago 7500921 Chile Details
Orlandi Oncología RECRUITING Santiago 7501010 Chile Details
Centro de Investigaciones Clinicas Vina Del Mar RECRUITING Vina Del Mar 254-0488 Chile Details
Guangxi Medical University Affiliated Tumor Hospital RECRUITING Nanning Guangxi 530021 China Details
Henan Cancer Hospital RECRUITING Zhengzhou Henan 450008 China Details
Jilin Cancer Hospital RECRUITING Changchun Jilin 130012 China Details
Sichuan Cancer Hospital RECRUITING Chengdu Sichuan 610049 China Details
Peking University Peoples Hospital RECRUITING Beijing 100044 China Details
Peking University Cancer Hospital RECRUITING Beijing 100142 China Details
Cangzhou People's Hospital RECRUITING Cangzhou 610001 China Details
Hunan Cancer Hospital RECRUITING Changsha 410013 China Details
Army Medical Center of PLA RECRUITING Chongqing 400042 China Details
Affiliated Cancer Hospital and Institute of Guangzhou Medical University RECRUITING Guangzhou 510095 China Details
Haikou People's Hospital RECRUITING Haikou 570208 China Details
The First Affiliated Hospital of College of Medicine Zhejiang University RECRUITING Hanghzou 310003 China Details
Zhejiang Cancer Hospital WITHDRAWN Hangzhou 310022 China Details
Harbin Medical University Cancer Hospital RECRUITING Harbin 150081 China Details
Inner Mongolia Medical University- the Affiliated Hospital RECRUITING Hohhot 10050 China Details
Jiamusi Tumor and Tuberculosis Hospital RECRUITING Jiamusi 154007 China Details
Yunnan Cancer Hospital RECRUITING Kunming 650118 China Details
Linyi Cancer Hospital RECRUITING Linyi 276000 China Details
The First Affiliated Hospital of Nanchang University RECRUITING Nanchang 330006 China Details
Jiangsu Province Hospital RECRUITING Nanjing 210029 China Details
The Second People's Hospital of Neijiang RECRUITING Neijiang 641000 China Details
Fudan University Shanghai Cancer Center RECRUITING Shanghai Shi 200032 China Details
Shanghai Pulmonary Hospital RECRUITING Shanghai 200433 China Details
Liaoning Cancer Hospital& Institute RECRUITING Shenyang City 110801 China Details
The First Hospital of China Medical University RECRUITING Shenyang 110001 China Details
Tianjin Medical University General Hospital RECRUITING Tianjin 300052 China Details
Union Hospital Affiliated With Tongji Medical College Huazhong University of Science and Technology RECRUITING Wuhan 430022 China Details
Hubei Cancer Hospital RECRUITING Wuhan 430079 China Details
The First Affiliate Hospitalof Xi'An Jiaotong University RECRUITING Xi'an 710061 China Details
The First Affiliated Hospital Xiamen University RECRUITING Xiamen 361001 China Details
Xiangyang Central Hospital- 5 Lumen Avenue RECRUITING Xiangyang 441000 China Details
Xinjiang Tumor Hospital RECRUITING Ürümqi 830000 China Details
Bordeaux University Hospital - Hopital Saint Andre RECRUITING Bordeaux 33075 France Details
Institut Bergonie RECRUITING Bordeaux 33076 France Details
Centre Hospitalier Universitaire de Lille RECRUITING Lille 59000 France Details
Centre Leon Berard RECRUITING Lyon 69008 France Details
APHM - Hopital Nord RECRUITING Marseille 13015 France Details
Centre Hospitalier Universitaire de Montpellier RECRUITING Montpellier 34295 France Details
Hopital prive du Confluent RECRUITING Nantes Cedex 2 44277 France Details
CHU de Nantes RECRUITING Nantes 44093 France Details
AP-HP - Hopital Tenon RECRUITING Paris 75970 France Details
CHU de Poitier Pole Regional de Cancerologie RECRUITING Poitiers 86000 France Details
Hopital FOCH RECRUITING Suresnes 92150 France Details
Evangelische Lungenklinik Berlin RECRUITING Berlin 13125 Germany Details
Klinikum Esslingen GmbH RECRUITING Esslingen 73730 Germany Details
LungenClinic Grosshansdorf RECRUITING Grosshansdorf 22927 Germany Details
Klinikum der Universitaet Muenchen RECRUITING Muenchen 80336 Germany Details
Metropolitan Hospital RECRUITING Neo Faliro Athens 14564 Greece Details
Sotiria General Hosptial of Chest Diseases RECRUITING Athens 11527 Greece Details
University Hospital of Ioannina Uhi RECRUITING Ioannina 45500 Greece Details
Metropolitan Hospital RECRUITING Neo Faliro 18547 Greece Details
Bioclinic Thessaloniki RECRUITING Thessaloniki 54622 Greece Details
Prince of Wales Hospital / The Chinese University of Hong Kong 99999 RECRUITING Hong Kong 99999 Hong Kong Details
Queen Elizabeth Hospital RECRUITING Hong Kong Hong Kong Details
Queen Mary Hospital RECRUITING Pok Fu Lam 999077 Hong Kong Details
Semmelweis University Department of Pulmonology RECRUITING Budapest 1083 Hungary Details
Veszprem Megyei Tudogyogyintezet Farkasgyepu RECRUITING Farkasgyepű 8582 Hungary Details
Bkmk Hospital RECRUITING KecskemĂŠt 6000 Hungary Details
Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz RECRUITING Szekesfehervar 8000 Hungary Details
Pulmonology Hospital Torokbalint RECRUITING Torokbalint 2045 Hungary Details
IRCCS Istituto Oncologico Giovanni Paolo II RECRUITING Bari 70124 Italy Details
UOC Oncologia RECRUITING Chieti 66100 Italy Details
IRCCS Ospedale San Raffaele RECRUITING Milano 20132 Italy Details
Irccs Istituto Europeo Di Oncologia RECRUITING Milano 20141 Italy Details
Azienda Ospedaliera dei Colli RECRUITING Naples 80131 Italy Details
A.O. Perugia Santa Maria della Misericordia RECRUITING Perugia 06132 Italy Details
Policlinico Tor Vergata RECRUITING Rome 133 Italy Details
Ifo Regina Elena RECRUITING Rome 144 Italy Details
Asst Sette Laghi Ospedale di Circolo e Fondazione Macchi RECRUITING Varese 21100 Italy Details
Aomori Prefectural Central Hospital RECRUITING Aomori-shi Aomori 030-8553 Japan Details
National Cancer Center Hospital East RECRUITING Kashiwa-shi Chiba 277-8577 Japan Details
NHO Shikoku Cancer Center RECRUITING Matsuyama-shi Ehime 791-0280 Japan Details
National Hospital Organization Kyushu Cancer Center RECRUITING Fukuoka-shi Fukuoka 811-1395 Japan Details
Kyushu University Hospital RECRUITING Fukuoka-shi Fukuoka 812-8582 Japan Details
Kurume University Hospital RECRUITING Kurume-shi Fukuoka 830-0011 Japan Details
Kanazawa University Hospital RECRUITING Kanazawa-shi Ishikawa 920-8641 Japan Details
Kanagawa Cancer Center RECRUITING Yokohama-shi Kanagawa 241-8515 Japan Details
Saiseikai Kumamoto Hospital RECRUITING Kumamoto-shi Kumamoto 861- 4193 Japan Details
Matsusaka Municipal Hospital RECRUITING Matsusaka-shi Mie 515-8544 Japan Details
Sendai Kousei Hospital RECRUITING Sendai-shi Miyagi 980-0873 Japan Details
Niigata Cancer Center Hospital RECRUITING Niigata-shi Niigata 961-8566 Japan Details
Kansai Medical University Hospital RECRUITING Hirakata-shi Osaka 573-1191 Japan Details
Osaka International Cancer Institute RECRUITING Osaka-shi Osaka 541-8567 Japan Details
NHO Kinki-Chuo Chest Medical Center RECRUITING Sakai-shi Osaka 591-8555 Japan Details
Saitama Cancer Center RECRUITING Ina-machi Saitama 362-0806 Japan Details
Dokkyo Medical University Hospital RECRUITING Shimotsuga-gun Tochigi 321-0293 Japan Details
Juntendo University Hospital RECRUITING Bunkyo-ku Tokyo 113-8431 Japan Details
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital RECRUITING Bunkyō-Ku Tokyo 113-8677 Japan Details
The Cancer Institute Hospital of JFCR RECRUITING Koto-ku Toyko 135-8550 Japan Details
Toho University Omori Medical Center RECRUITING Ota-ku Toyko 143-8541 Japan Details
NHO Iwakuni Clinical Center RECRUITING Iwakuni-shi Yamaguchi 740-8510 Japan Details
Yamaguchi-Ube Medical Center RECRUITING Ube-shi Yamaguchi 755-0241 Japan Details
Yamanashi Prefectural Central Hospital RECRUITING Kofu-shi Japan Details
University Hospital Kyoto Prefectural University of Medicine RECRUITING Kyoto-shi 602-8566 Japan Details
Osaka Toneyama Medical Center RECRUITING Osaka 560-8552 Japan Details
Teine Keijinkai Hospital RECRUITING Sapporo 006-8555 Japan Details
Chungbuk National University Hospital RECRUITING Cheongju-si Chungbuk 28644 Korea, Republic of Details
Seoul National University Bundang Hospital RECRUITING Seongnam Gyeonggi-do 13620 Korea, Republic of Details
Gyeongsang National University Hospital RECRUITING Jinju-si Gyeongsangnam-do 52727 Korea, Republic of Details
Kyungpook National University Chilgok Hospital RECRUITING Daegu 42119 Korea, Republic of Details
National Cancer Center RECRUITING Goyang-si 10408 Korea, Republic of Details
Samsung Medical Center RECRUITING Seoul 6351 Korea, Republic of Details
The Catholic Univ. of Korea, Seoul St. Mary'S Hospital RECRUITING Seoul 6591 Korea, Republic of Details
Asan Medical Center RECRUITING Songpa-gu 5505 Korea, Republic of Details
Cryptex Investigacion Clinica Sa de Cv RECRUITING Cuauhtémoc 06100 Mexico Details
Hospital Civil de Guadalajara Fray Antonio Alcalde RECRUITING Guadalajara 44280 Mexico Details
Hospital Universitario Dr. Jose Eleuterio Gonzalez RECRUITING Monterrey 64460 Mexico Details
Centro de Investigacion Clinica de Oaxaca (CICLO) RECRUITING Oaxaca de Juarez 68020 Mexico Details
Oncologico Potosino RECRUITING San Luis Potosí 78209 Mexico Details
Rijnstate Ziekenhuis RECRUITING Arnhem Gelderland 6815 AD Netherlands Details
Amsterdam Umc, Location Vumc RECRUITING Amsterdam 1081 HZ Netherlands Details
Leiden University Medical Center RECRUITING Leiden 2333 ZA Netherlands Details
Jeroen Bosch Ziekenhuis J BZ Hieronymus Bosch Hospital RECRUITING s-Hertogenbosch 5223 GZ Netherlands Details
Instytut Centrum Zdrowia Matki Polki RECRUITING Lodz Iodzkie 93-338 Poland Details
Szpitale Pomorskie Sp. z o.o. RECRUITING Gdynia Pomorskie 81-519 Poland Details
Dom Lekarski SA RECRUITING Szczecin Zachodniopomorskie 70-784 Poland Details
II Klinika Chorob Pluc I Gruzlicy RECRUITING Bialystok 15-450 Poland Details
MS Pneumed Janusz Milanowski, Katarzyna Szmygin-Milanowska Sp. Jawna RECRUITING Lublin 20-064 Poland Details
Centro Clinico Champalimau RECRUITING Lisboa 1400-038 Portugal Details
Centro Hospitalar e Universitário do Porto RECRUITING Porto 4099-001 Portugal Details
Hospital CUF Porto RECRUITING Porto 4100-180 Portugal Details
Instituto Portuguas de Oncologia do Porto Francisco Gentil RECRUITING Porto 4200-072 Portugal Details
Centro Hospitalar Universitário de São João RECRUITING Porto 4200-319 Portugal Details
Onco Clinic Consult SA RECRUITING Craiova 200094 Romania Details
Sc Sigmedical Services Srl RECRUITING Suceava 720214 Romania Details
Oncocenter-Oncologie Clinica SRL RECRUITING Timisoara 300166 Romania Details
SC Oncomed SRL RECRUITING Timisoara 300239 Romania Details
Hospital Clinic i Provincial de Barcelona RECRUITING Barcelona 08036 Spain Details
Hospital Universitari Vall D'Hebron RECRUITING Barcelona 8035 Spain Details
Hospital Universitario Arnau de Vilanova - Lleida RECRUITING Lleida 25198 Spain Details
Hospital General Universitario Gregorio Marañon RECRUITING Madrid 28007 Spain Details
Hospital Clinico San Carlos RECRUITING Madrid 28040 Spain Details
Hospital Universitario Fundacion Jimenez Diaz RECRUITING Madrid 28040 Spain Details
Hospital Regional Universitario Malaga RECRUITING Malaga 29010 Spain Details
CHUO RECRUITING Ourense 32005 Spain Details
Hospital Universitario Virgen Macarena RECRUITING Sevilla 41009 Spain Details
Hospital Universitario de Valme RECRUITING Sevilla 41014 Spain Details
Hospital Universitari i Politècnic La Fe RECRUITING Valencia 46026 Spain Details
Hospital Universitario Miguel Servet RECRUITING Zaragoza 50009 Spain Details
Kantonsspital Baden RECRUITING Baden 5404 Switzerland Details
University Hospital Basel RECRUITING Basel 4031 Switzerland Details
Kantonsspital Baselland RECRUITING Liestal A4410 Switzerland Details
Kantonsspital St. Gallen RECRUITING St.Gallen Switzerland Details
E-Da Hospital RECRUITING Kaohsiung City 824 Taiwan Details
Chang Gung Memorial Hospital Cgmh - Kaohsiung Branch RECRUITING Kaohsiung 833 Taiwan Details
Chung Shan Medical University Hospital RECRUITING Taichung 40201 Taiwan Details
Taichung Veterans General Hospital RECRUITING Taichung 40705 Taiwan Details
National Cheng Kung University Hospital Nckuh RECRUITING Tainan 704 Taiwan Details
Taipei Veterans General Hospital RECRUITING Taipei City 11217 Taiwan Details
National Taiwan University Hospital RECRUITING Taipei 100 Taiwan Details
Koo Foundation Sun Yat-Sen Cancer Center RECRUITING Taipei 112 Taiwan Details
Chang Gung Memorial Hospital LinKou RECRUITING Taoyuan 333 Taiwan Details
Srinagarind Hospital RECRUITING Muaeng Khon Kaen 40002 Thailand Details
Prince of Songkla University PSU - Faculty of Medicine RECRUITING Hat Yai Songkhla 90110 Thailand Details
Faculty of Medicine Chulalongkorn University RECRUITING Bangkok 10330 Thailand Details
Siriraj Hospital RECRUITING Bangkok 10700 Thailand Details
Adana Acibadem Hospital RECRUITING Adana 1130 Turkey Details
Ege University RECRUITING Bornova-İzmir 35100 Turkey Details
Goztepe Prof. Dr. Suleyman Yalcin City Hospital RECRUITING İstanbul 34772 Turkey Details
Medical Park Seyhan Hospital RECRUITING Seyhan /Adana 1140 Turkey Details
Birmingham Heartlands Hospital RECRUITING Birmingham B9 5SS United Kingdom Details
Beatson West of Scotland Cancer Centre RECRUITING Glasgow G12 0YN United Kingdom Details
Nottingham University Hospitals RECRUITING Nottingham NG5 1PB United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field