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| NCT ID | NCT05218499 |
| Title | Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Boehringer Ingelheim |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | SWE | NOR | NLD | ITA | GRC | GBR | FRA | FIN | ESP | DNK | DEU | CZE | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | United States | Details | |
| University of Arizona | Tucson | Arizona | 85719 | United States | Details | |
| Precision NextGen Oncology | Beverly Hills | California | 90212 | United States | Details | |
| City of Hope-Duarte-56419 | Duarte | California | 91010 | United States | Details | |
| University of Southern California | Los Angeles | California | 90033 | United States | Details | |
| Sarcoma Oncology Center | Santa Monica | California | 90403 | United States | Details | |
| Mayo Clinic Cancer Center | Jacksonville | Florida | 32224 | United States | Details | |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | United States | Details | |
| Mayo Clinic, Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| Barnes-Jewish Hospital | Saint Louis | Missouri | 63110 | United States | Details | |
| Nebraska Cancer Specialists-Omaha-69502 | Omaha | Nebraska | 68114 | United States | Details | |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | United States | Details | |
| Oregon Health and Sciences University | Portland | Oregon | 97239 | United States | Details | |
| Henry-Joyce Cancer Clinic | Nashville | Tennessee | 37232 | United States | Details | |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | United States | Details | |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | United States | Details | |
| Froedtert and The Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| Prince of Wales Hospital-Randwick-66496 | Randwick | New South Wales | 2031 | Australia | Details | |
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Ashford Cancer Centre Research | Kurralta Park | South Australia | 5037 | Australia | Details | |
| Peter MacCallum Cancer Centre | Melbourne | Victoria | 3000 | Australia | Details | |
| UZ Leuven | Leuven | 3000 | Belgium | Details | ||
| BC Cancer Agency - Vancouver | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| The Ottawa Hospital | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Maisonneuve-Rosemont Hospital | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| Cancer Hospital of Chinese Academy of Medical Science | Beijing | 100021 | China | Details | ||
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| The First Hospital of Jilin University | Changchun | 130021 | China | Details | ||
| West China Hospital | Chengdu | 610041 | China | Details | ||
| Sun Yat-Sen University Cancer Center | Guangzhou | 510060 | China | Details | ||
| Zhejiang Cancer Hospital | Hangzhou | 310022 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Zhongshan Hospital Affiliated to Fudan University | Shanghai | 200032 | China | Details | ||
| Wuhan Union Hospital | Wuhan | 430022 | China | Details | ||
| Masaryk Memorial Cancer Institute | Brno | 65653 | Czechia | Details | ||
| University Hospital Olomouc | Olomouc | 77900 | Czechia | Details | ||
| University Hospital Motol | Prague 5 | 150 06 | Czechia | Details | ||
| Herlev and Gentofte Hospital | Herlev | 2730 | Denmark | Details | ||
| HUCH Comprehensive Cancer Center, building 2 | Helsinki | 00290 | Finland | Details | ||
| Tampere University Hospital | Tampere | 33520 | Finland | Details | ||
| INS Bergonie | Bordeaux | 33000 | France | Details | ||
| CTR Oscar Lambret | Lille | 59020 | France | Details | ||
| CTR Leon Berard | Lyon | 69373 | France | Details | ||
| HOP Timone | Marseille | 13385 | France | Details | ||
| HOP Cochin | Paris | 75014 | France | Details | ||
| CTR Eugène Marquis | Rennes | 35042 | France | Details | ||
| INS Claudius Regaud IUCT-Oncopole | Toulouse | 31059 | France | Details | ||
| INS Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Helios Klinikum Bad Saarow | Bad Saarow | 15526 | Germany | Details | ||
| Helios Klinikum Berlin-Buch | Berlin | 13125 | Germany | Details | ||
| Technische Universität Dresden | Dresden | 01307 | Germany | Details | ||
| Universitätsklinikum Essen AöR | Essen | 45147 | Germany | Details | ||
| Asklepios Kliniken GmbH & Co. KGaA | Hamburg | 22763 | Germany | Details | ||
| Medizinische Hochschule Hannover | Hannover | 30625 | Germany | Details | ||
| Universitätsklinikum Mannheim GmbH | Mannheim | 68167 | Germany | Details | ||
| Klinikum der Universität München AÖR | München | 81377 | Germany | Details | ||
| Robert Bosch Gesellschaft für medizinische Forschung mbH | Stuttgart | 70376 | Germany | Details | ||
| Hippokration General Hospital of Athen | Athens | 115 27 | Greece | Details | ||
| "Attikon" University General Hospital of Attica | Haidari | 12462 | Greece | Details | ||
| Bioclinic Thessaloniki | Thessaloniki | 54622 | Greece | Details | ||
| Prince of Wales Hospital-Hong Kong-20715 | Hong Kong | Hong Kong | Details | |||
| Humanitas Gavazzeni | Bergamo | 24125 | Italy | Details | ||
| Istituto Di Candiolo | Candiolo (TO) | 10060 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | 20133 | Italy | Details | ||
| Istituto Nazionale IRCCS Tumori Fondazione Pascale | Napoli | 80131 | Italy | Details | ||
| AOU San Luigi Gonzaga | Orbassano (TO) | 10043 | Italy | Details | ||
| Istituto Oncologico Veneto IRCCS | Padova | 35128 | Italy | Details | ||
| A.O. Univ. Policlinico Giaccone | Palermo | 90129 | Italy | Details | ||
| Università Campus Bio-Medico - ROMA | Roma | 00128 | Italy | Details | ||
| Aichi Cancer Center Hospital | Aichi, Nagoya | 464-8681 | Japan | Details | ||
| Nagoya University Hospital | Aichi, Nagoya | 466-8560 | Japan | Details | ||
| National Cancer Center Hospital East | Chiba, Kashiwa | 277-8577 | Japan | Details | ||
| National Hospital Organization Kyushu Cancer Center | Fukuoka, Fukuoka | 811-1395 | Japan | Details | ||
| Kyushu University Hospital | Fukuoka, Fukuoka | 812-8582 | Japan | Details | ||
| Tohoku University Hospital | Miyagi, Sendai | 980-8574 | Japan | Details | ||
| Okayama University Hospital | Okayama, Okayama | 700-8558 | Japan | Details | ||
| Osaka International Cancer Institute | Osaka, Osaka | 541-8567 | Japan | Details | ||
| Hokkaido Cancer Center | Sapporo, Hokkaido | 003-0804 | Japan | Details | ||
| National Cancer Center Hospital | Tokyo, Chuo-ku | 104-0045 | Japan | Details | ||
| Japanese Foundation for Cancer Research | Tokyo, Koto-ku | 135-8550 | Japan | Details | ||
| Nederlands Kanker Instituut | Amsterdam | 1066 CX | Netherlands | Details | ||
| Leids Universitair Medisch Centrum (LUMC) | Leiden | 2333 ZA | Netherlands | Details | ||
| Oslo Universitetssykehus HF, Radiumhospitalet | Oslo | N-0379 | Norway | Details | ||
| IPO Lisboa Francisco Gentil, EPE | Lisboa | 1099-023 | Portugal | Details | ||
| ULS de Santa Maria, E.P.E | Lisboa | 1649-035 | Portugal | Details | ||
| Hospital Santa Creu i Sant Pau | Barcelona | 08026 | Spain | Details | ||
| Hospital Vall d'Hebron-Barcelona-47683 | Barcelona | 08035 | Spain | Details | ||
| Hospital Duran i Reynals | L'Hospitalet de Llobregat | 08907 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañón | Madrid | 28007 | Spain | Details | ||
| Fundación Jiménez Díaz | Madrid | 28040 | Spain | Details | ||
| Hospital La Paz | Madrid | 28046 | Spain | Details | ||
| Hospital Universitario HM Sanchinarro | Madrid | 28050 | Spain | Details | ||
| Hospital Virgen de la Victoria | Malaga | 29010 | Spain | Details | ||
| Hospital Clínico de Santiago | Santiago de Compostela | 15706 | Spain | Details | ||
| Hospital Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| Skånes universitetssjukhus | Lund | 22185 | Sweden | Details | ||
| Karolinska Universitetssjukhuset Stockholm | Stockholm | 17177 | Sweden | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Addenbrooke's Hospital | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Velindre Cancer Centre | Cardiff | CF14 2TL | United Kingdom | Details | ||
| Churchill Hospital | Headington | OX3 9DS | United Kingdom | Details | ||
| University College Hospital | London | NW1 2BU | United Kingdom | Details | ||
| The Royal Marsden Hospital, Chelsea | London | SW3 6JJ | United Kingdom | Details |