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| NCT ID | NCT05224141 |
| Title | Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008, KEYVIBE-008) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | ROU | POL | NLD | LTU | ITA | ISR | IRL | HUN | GRC | GBR | FRA | FIN | ESP | DEU | CAN | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Infirmary Cancer Care ( Site 0022) | Mobile | Alabama | 36652 | United States | Details | |
| Los Angeles Hematology Oncology Medical Group ( Site 0006) | Los Angeles | California | 90017 | United States | Details | |
| VA West Los Angeles Medical Center ( Site 0004) | Los Angeles | California | 90073 | United States | Details | |
| Boca Raton Regional Hospital-Lynn Cancer Institute ( Site 0014) | Boca Raton | Florida | 33486 | United States | Details | |
| Fort Wayne Medical Oncology and Hematology ( Site 0013) | Fort Wayne | Indiana | 46804 | United States | Details | |
| Dana-Farber Cancer Institute ( Site 0018) | Boston | Massachusetts | 02215 | United States | Details | |
| Cancer and Hematology Centers of Western Michigan ( Site 0001) | Grand Rapids | Michigan | 49503 | United States | Details | |
| Hattiesburg Clinic Hematology/Oncology ( Site 0003) | Hattiesburg | Mississippi | 39401 | United States | Details | |
| Lancaster General Hospital - Ann B Barshinger Cancer Institute ( Site 0005) | Lancaster | Pennsylvania | 17601 | United States | Details | |
| Blue Ridge Cancer Care ( Site 0015) | Blacksburg | Virginia | 24060 | United States | Details | |
| University of Virginia Cancer Center ( Site 0019) | Charlottesville | Virginia | 22903 | United States | Details | |
| Instituto de Investigaciones Clínicas Mar del Plata ( Site 0201) | Mar del Plata | Buenos Aires | 7600 | Argentina | Details | |
| Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 0203) | ABB | Caba | C1199ABB | Argentina | Details | |
| Centro de Educación Médica e Investigaciones Clínicas (CEMIC)-Medical Oncology ( Site 0200) | Buenos Aires | Caba | C1431FWO | Argentina | Details | |
| Sanatorio Parque ( Site 0202) | Rosario | Santa Fe | 2000 | Argentina | Details | |
| Hospital Provincial del Centenario ( Site 0205) | Rosario | Santa Fe | 2002 | Argentina | Details | |
| Nepean Hospital ( Site 2700) | Penrith | New South Wales | 2747 | Australia | Details | |
| Calvary Mater Newcastle ( Site 2703) | Waratah | New South Wales | 2298 | Australia | Details | |
| Frankston Hospital-Oncology and Haematology ( Site 2702) | Frankston | Victoria | 3199 | Australia | Details | |
| Western Health-Sunshine & Footscray Hospitals-Cancer Services-Cancer Research ( Site 2701) | St Albans | Victoria | 3021 | Australia | Details | |
| Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0505) | Linz | Oberosterreich | 4020 | Austria | Details | |
| Kepler Universitätsklinikum ( Site 0507) | Linz | Oberosterreich | 4021 | Austria | Details | |
| Medizinische Universität Graz ( Site 0504) | Graz | Steiermark | 8036 | Austria | Details | |
| Klinik Penzing-2. Lungenabteilung ( Site 0502) | Vienna | Wien | 1140 | Austria | Details | |
| Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0501) | Wien | 1210 | Austria | Details | ||
| Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 0106) | Kingston | Ontario | K7L 2V7 | Canada | Details | |
| Lakeridge Health ( Site 0102) | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| Anhui Cancer Hospital ( Site 2915) | Hefei | Anhui | 230031 | China | Details | |
| Beijing Cancer hospital-Thoracic Cancer Department A ( Site 2901) | Beijing | Beijing | 100142 | China | Details | |
| Beijing Peking Union Medical College Hospital ( Site 2921) | Beijing | Beijing | 100730 | China | Details | |
| Fujian Provincial Cancer Hospital-oncology department ( Site 2904) | Fuzhou | Fujian | 350014 | China | Details | |
| Harbin Medical University Cancer Hospital-oncology of department ( Site 2920) | Harbin | Heilongjiang | 150081 | China | Details | |
| Henan Cancer Hospital ( Site 2916) | Zhengzhou | Henan | 450008 | China | Details | |
| Wuhan Union Hospital Cancer Center-Cancer Center ( Site 2912) | Wuhan | Hubei | 430022 | China | Details | |
| Hubei Cancer Hospital ( Site 2922) | Wuhan | Hubei | 430079 | China | Details | |
| Hunan Cancer Hospital ( Site 2907) | Changsha | Hunan | 410013 | China | Details | |
| The First Affiliated Hospital of Soochow University ( Site 2913) | Suzhou | Jiangsu | 215006 | China | Details | |
| Jilin Cancer Hospital-GCP office ( Site 2909) | Changchun | Jilin | 130000 | China | Details | |
| The First Hospital of Jilin University ( Site 2914) | Changchun | Jilin | 130021 | China | Details | |
| The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 2910) | Xi'an | Shaanxi | 710061 | China | Details | |
| Shanghai Chest Hospital-Oncology department ( Site 2900) | Shanghai | Shanghai | 200030 | China | Details | |
| Fudan University Shanghai Cancer Center ( Site 2908) | Shanghai | Shanghai | 200032 | China | Details | |
| Sichuan Cancer hospital ( Site 2923) | Chengdu | Sichuan | 610041 | China | Details | |
| West China Hospital Sichuan University ( Site 2903) | Chengdu | Sichuan | 611135 | China | Details | |
| Sir Run Run Shaw Hospital-Medical Oncology ( Site 2906) | Hangzhou | Zhejiang | 310016 | China | Details | |
| Zhejiang Cancer Hospital-Oncology ( Site 2919) | Hangzhou | Zhejiang | 310022 | China | Details | |
| Vaasan Keskussairaala-Department of Clinical Oncology ( Site 0700) | Vaasa | Pohjanmaa | 65130 | Finland | Details | |
| Oulun yliopistollinen sairaala-Oncology and Hematology ( Site 0702) | Oulu | Pohjois-Pohjanmaa | 90220 | Finland | Details | |
| Turku University Hospital-The Department of Pulmonary Medicine ( Site 0701) | Turku | Varsinais-Suomi | 20521 | Finland | Details | |
| Assistance Publique Hôpitaux de Marseille - Hôpital Nord ( Site 0805) | Marseille | Bouches-du-Rhone | 13915 | France | Details | |
| CHU de Toulouse - Hopital Larrey-service de pneumologie ( Site 0800) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Centre Hospitalier Universitaire de Limoges - Hôpital Dupuyt-Unité d'oncologie thoracique et cutané | Limoges | Haute-Vienne | 87042 | France | Details | |
| Thoraxklinik-Heidelberg gGmbH-Studienzentrum Thoraxonkologie ( Site 0905) | Heidelberg | Baden-Wurttemberg | 69126 | Germany | Details | |
| Lungenfachklinik Immenhausen-Thoracic Oncology ( Site 0907) | Immenhausen | Hessen | 34376 | Germany | Details | |
| Medizinische Hochschule Hannover-Department of Pneumology ( Site 0901) | Hannover | Niedersachsen | 30625 | Germany | Details | |
| LungenClinic Grosshansdorf-Onkologie ( Site 0903) | Grosshansdorf | Schleswig-Holstein | 22927 | Germany | Details | |
| SRH Wald-Klinikum Gera-Lungenkrebszentrum ( Site 0900) | Gera | Thuringen | 07548 | Germany | Details | |
| Errikos Dunant Hospital Center-Second Department of Oncology and Clinical Trials Unit ( Site 1002) | Athens | Attiki | 115 26 | Greece | Details | |
| Sotiria Thoracic Diseases Hospital of Athens ( Site 1003) | Athens | Attiki | 11527 | Greece | Details | |
| Metropolitan Hospital ( Site 1001) | Athens | Attiki | 185 47 | Greece | Details | |
| University General Hospital of Heraklion ( Site 1004) | Heraklion | Irakleio | 711 10 | Greece | Details | |
| European Interbalkan Medical Center ( Site 1000) | Thessaloniki | 570 01 | Greece | Details | ||
| Bacs-Kiskun Megyei Korhaz-Onkoradiologiai Kozpont ( Site 1105) | Kecskemét | Bacs-Kiskun | 6000 | Hungary | Details | |
| Petz Aladar Egyetemi Oktato Korhaz-Pulmonológia (Dr. Szalai Zsuzsanna) ( Site 1102) | Gyor | Gyor-Moson-Sopron | 9024 | Hungary | Details | |
| Torokbalint Tudogyogyintezet-Onkopulmonologiai Jarobeteg Centrum ( Site 1101) | Törökbálint | Pest | 2045 | Hungary | Details | |
| Somogy Megyei Kaposi Mór Oktató Kórház-Pulmonologiai Osztaly ( Site 1104) | Kaposvár | Somogy | 7400 | Hungary | Details | |
| St. James's Hospital ( Site 1200) | Dublin | D08 E9P6 | Ireland | Details | ||
| Beaumont Hospital, Dublin-Cancer Clinical Trials & Research Unit ( Site 1201) | Dublin | Dublin 9 | Ireland | Details | ||
| Rambam Health Care Campus-Oncology ( Site 1301) | Haifa | 3109601 | Israel | Details | ||
| Shaare Zedek Medical Center-Oncology ( Site 1300) | Jerusalem | 9103102 | Israel | Details | ||
| Sheba Medical Center-ONCOLOGY ( Site 1302) | Ramat Gan | 5265601 | Israel | Details | ||
| Azienda Ospedaliera Dei Colli-U.O.C Pneumologia Oncologica DH PNL ONC ( Site 1402) | Naples | Campania | 80131 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 1401) | Milan | Lombardia | 20133 | Italy | Details | |
| Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1403) | Rozzano | Milano | 20089 | Italy | Details | |
| Istituto Nazionale Tumori Regina Elena-Oncologia Medica 2 ( Site 1400) | Rome | Roma | 00144 | Italy | Details | |
| Aichi Cancer Center Hospital ( Site 3016) | Nagoya | Aichi | 464-8681 | Japan | Details | |
| National Cancer Center Hospital East ( Site 3002) | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| National Hospital Organization Shikoku Cancer Center ( Site 3012) | Matsuyama | Ehime | 791-0280 | Japan | Details | |
| Kurume University Hospital ( Site 3014) | Kurume | Fukuoka | 830-0011 | Japan | Details | |
| National Hospital Organization Hokkaido Cancer Center ( Site 3015) | Sapporo | Hokkaido | 003-0804 | Japan | Details | |
| Kanazawa University Hospital ( Site 3006) | Kanazawa | Ishikawa | 920-8641 | Japan | Details | |
| Kanagawa cancer center-Department of Thoracic Oncology ( Site 3004) | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
| Sendai Kousei Hospital ( Site 3001) | Sendai | Miyagi | 9800873 | Japan | Details | |
| Niigata Cancer Center Hospital ( Site 3005) | Niigata-shi | Niigata | 951-8566 | Japan | Details | |
| Kansai Medical University Hospital ( Site 3009) | Hirakata | Osaka | 573-1191 | Japan | Details | |
| Shizuoka Cancer Center ( Site 3007) | Nagaizumi | Shizuoka | 411-8777 | Japan | Details | |
| Japanese Foundation for Cancer Research ( Site 3003) | Koto | Tokyo | 135-8550 | Japan | Details | |
| National Hospital Organization Kyushu Medical Center ( Site 3013) | Fukuoka | 810-8563 | Japan | Details | ||
| Okayama University Hospital ( Site 3011) | Okayama | 700-8558 | Japan | Details | ||
| Chonnam National University Hwasun Hospital-Pulmonology ( Site 2800) | Hwasun | Jeonranamdo | 58128 | Korea, Republic of | Details | |
| Kyungpook National University Chilgok Hospital-Pulmonology ( Site 2801) | Deagu | Taegu-Kwangyokshi | 41404 | Korea, Republic of | Details | |
| Chungnam national university hospital-Department of Internal Medicine ( Site 2802) | Daejeon | Taejon-Kwangyokshi | 35015 | Korea, Republic of | Details | |
| Korea University Guro Hospital-Internal Medicine ( Site 2803) | Seoul | Korea, Republic of | Details | |||
| Klaipeda University Hospital-Oncology chemotherapy ( Site 1502) | Klaipeda | Klaipedos Miestas | 92288 | Lithuania | Details | |
| National Cancer Institute-Department of Thoracic Surgery and Oncology ( Site 1501) | Vilnius | Vilniaus Miestas | 08406 | Lithuania | Details | |
| Hospital of Lithuanian University of Health Sciences Kauno klinikos-Pulmonology ( Site 1500) | Kaunas | LT-50161 | Lithuania | Details | ||
| Arké SMO S.A. de C.V. ( Site 0401) | Mexico | Distrito Federal | 06700 | Mexico | Details | |
| Hospital Civil Fray Antonio Alcalde-Oncology ( Site 0407) | Guadalajara | Jalisco | 44280 | Mexico | Details | |
| Actualidad Basada en la Investigación del Cáncer-Lung Cancer ( Site 0403) | Guadalajara | Jalisco | 44680 | Mexico | Details | |
| iCan Oncology Center Centro Medico AVE ( Site 0406) | Monterrey | Nuevo Leon | 64710 | Mexico | Details | |
| Centro de Investigacion Clinica de Oaxaca ( Site 0410) | Oaxaca | 68020 | Mexico | Details | ||
| Medische Centrum Leeuwarden ( Site 1619) | Leeuwarden | Fryslan | 8934 AD | Netherlands | Details | |
| Ziekenhuis Rijnstate ( Site 1606) | Arnhem | Gelderland | 6815 AD | Netherlands | Details | |
| Maastricht UMC+-Pulmonary disease ( Site 1602) | Maastricht | Limburg | 6229 HX | Netherlands | Details | |
| Jeroen Bosch Hospital-Pulmonology ( Site 1605) | Den Bosch | Noord-Brabant | 5223 GZ | Netherlands | Details | |
| Isala, locatie Zwolle-Poli Longziekten ( Site 1612) | Zwolle | Overijssel | 8025 AB | Netherlands | Details | |
| Erasmus Medisch Centrum ( Site 1621) | Rotterdam | Zuid-Holland | 3015 GD | Netherlands | Details | |
| Martini Ziekenhuis ( Site 1618) | Groningen | 9728 NT | Netherlands | Details | ||
| Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1709) | Siedlce | Mazowieckie | 08-110 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1703) | Przemysl | Podkarpackie | 37-700 | Poland | Details | |
| Szpital Specjalistyczny w Prabutach Spolka z o.o. ( Site 1706) | Prabuty | Pomorskie | 82-550 | Poland | Details | |
| Centrum Pulmonologii i Torakochirurgii w Bystrej ( Site 1707) | Bystra | Slaskie | 43-360 | Poland | Details | |
| Przychodnia Lekarska KOMED ( Site 1701) | Konin | Wielkopolskie | 62-500 | Poland | Details | |
| Med-Polonia Sp. z o. o. ( Site 1710) | Poznan | Wielkopolskie | 60-693 | Poland | Details | |
| Champalimaud Foundation ( Site 1812) | Lisbon | Lisboa | 1400-038 | Portugal | Details | |
| Hospital CUF Descobertas ( Site 1815) | Lisbon | Lisboa | 1998-018 | Portugal | Details | |
| Centro Hospitalar do Porto - Hospital de Santo António ( Site 1813) | Porto | 4099-001 | Portugal | Details | ||
| Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 1810) | Porto | 4200-072 | Portugal | Details | ||
| MedEuropa Bucuresti - Centru de Radioterapie-Oncology ( Site 1905) | București | Bucuresti | 022343 | Romania | Details | |
| Centrul medical Focus ( Site 1903) | București | Bucuresti | 022548 | Romania | Details | |
| Cardiomed SRL Cluj-Napoca ( Site 1900) | Cluj-Napoca | Cluj | 400015 | Romania | Details | |
| Centrul de Oncologie Oncolab-Medical Oncology ( Site 1904) | Craiova | Dolj | 200385 | Romania | Details | |
| Centrul de Oncologie "Sfântul Nectarie"-Medical Oncology ( Site 1901) | Craiova | Dolj | 200746 | Romania | Details | |
| Cabinet Medical Oncomed ( Site 1902) | Timișoara | Timis | 300239 | Romania | Details | |
| Hospital Universitario 12 de Octubre-Medical Oncology ( Site 2102) | Madrid | Madrid, Comunidad De | 28041 | Spain | Details | |
| H.R.U Málaga - Hospital General-Oncology ( Site 2104) | Málaga | Malaga | 29011 | Spain | Details | |
| Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2100) | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 2103) | Sevilla | 41009 | Spain | Details | ||
| Ege University Medicine of Faculty-Chest Diseases Department ( Site 2402) | Bornova | Izmir | 35100 | Turkey | Details | |
| I.E.U. Medical Point Hastanesi-Oncology ( Site 2408) | Izmir, Karsiyaka | Izmir | 009035575 | Turkey | Details | |
| Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 2407) | Adana | 01250 | Turkey | Details | ||
| Hacettepe Universitesi-oncology hospital ( Site 2409) | Ankara | 06230 | Turkey | Details | ||
| Memorial Ankara Hastanesi-Medical Oncology ( Site 2406) | Ankara | 06520 | Turkey | Details | ||
| Ankara Bilkent City Hospital ( Site 2403) | Ankara | 06800 | Turkey | Details | ||
| Medipol University Medical Faculty-oncology ( Site 2400) | Istanbul | 34214 | Turkey | Details | ||
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2401) | Istanbul | 34722 | Turkey | Details | ||
| The Christie-Clinical Research Facility ( Site 2607) | Manchester | England | M20 4bx | United Kingdom | Details | |
| Mount Vernon Hospital ( Site 2602) | Northwood | Hillingdon | HA6 2RN | United Kingdom | Details | |
| Heartlands Hospital-Oncology Research ( Site 2604) | Birmingham | B9 5SS | United Kingdom | Details |