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| NCT ID | NCT05226598 |
| Title | Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination With Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (MK-7684A-007/KEYVIBE-007) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | POL | ISR | GBR | FRA | ESP | DEU | BRA | AUT | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCHealth Memorial Hospital-Heme Onc ( Site 0003) | Colorado Springs | Colorado | 80909 | United States | Details | |
| University of Colorado Health - Harmony-Cancer Care and Hematology - Ft. Collins ( Site 0031) | Fort Collins | Colorado | 80528 | United States | Details | |
| Mayo Clinic in Florida ( Site 0022) | Jacksonville | Florida | 32224 | United States | Details | |
| Mount Sinai Hospital ( Site 0011) | Chicago | Illinois | 60608 | United States | Details | |
| University of Chicago Medical Center ( Site 0015) | Chicago | Illinois | 60637 | United States | Details | |
| New England Cancer Specialists ( Site 0008) | Scarborough | Maine | 04074 | United States | Details | |
| Cancer and Hematology Centers of Western Michigan ( Site 0002) | Grand Rapids | Michigan | 49503 | United States | Details | |
| Mayo Clinic in Rochester, Minnesota ( Site 0030) | Rochester | Minnesota | 55905 | United States | Details | |
| Stony Brook University-Cancer Center ( Site 0013) | Stony Brook | New York | 11794 | United States | Details | |
| Lancaster General Hospital - Ann B Barshinger Cancer Institute ( Site 0012) | Lancaster | Pennsylvania | 17604 | United States | Details | |
| Charleston Oncology ( Site 0019) | Charleston | South Carolina | 29414 | United States | Details | |
| University of Virginia Cancer Center ( Site 0018) | Charlottesville | Virginia | 22903 | United States | Details | |
| Centro de Oncología e Investigación de Buenos Aires ( Site 0203) | Berazategui | Buenos Aires | B1884BBF | Argentina | Details | |
| Instituto de Investigaciones Clínicas Mar del Plata ( Site 0204) | Mar del Plata | Buenos Aires | B7600FZO | Argentina | Details | |
| Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 0209) | ABB | Caba | C1199ABB | Argentina | Details | |
| Centro de Educación Médica e Investigaciones Clínicas (CEMIC)-Medical Oncology ( Site 0202) | Buenos Aires | Caba | C1431FWO | Argentina | Details | |
| Sanatorio Parque ( Site 0205) | Rosario | Santa Fe | 2000 | Argentina | Details | |
| Hospital Provincial del Centenario ( Site 0212) | Rosario | Santa Fe | 2002 | Argentina | Details | |
| Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0206) | La Rioja | F5300COE | Argentina | Details | ||
| Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0705) | Linz | Oberosterreich | 4020 | Austria | Details | |
| Kepler Universitätsklinikum ( Site 0707) | Linz | Oberosterreich | 4021 | Austria | Details | |
| Medizinische Universität Graz ( Site 0704) | Graz | Steiermark | 8036 | Austria | Details | |
| Medizinische Universitaet Innsbruck ( Site 0703) | Innsbruck | Tirol | 6020 | Austria | Details | |
| Klinik Penzing-2. Lungenabteilung ( Site 0702) | Vienna | Wien | 1140 | Austria | Details | |
| Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0701) | Wien | 1210 | Austria | Details | ||
| Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 0403) | Natal | Rio Grande Do Norte | 59075-740 | Brazil | Details | |
| Hospital Nossa Senhora da Conceição-Centro Integrado de Pesquisa em Oncologia ( Site 0405) | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details | |
| Clínica de Oncologia Reichow ( Site 0407) | Blumenau | Santa Catarina | 89010-340 | Brazil | Details | |
| Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA ( Site 0406) | Rio de Janeiro | 20230-130 | Brazil | Details | ||
| Hospital Paulistano ( Site 0401) | Sao Paulo | 01321-001 | Brazil | Details | ||
| James Lind Centro de Investigación del Cáncer ( Site 0502) | Temuco | Araucania | 4800827 | Chile | Details | |
| CIDO SpA-Oncology ( Site 0508) | Temuco | Araucania | 4810148 | Chile | Details | |
| Biocenter ( Site 0514) | Concepción | Biobio | 4070196 | Chile | Details | |
| FALP-UIDO ( Site 0505) | Santiago | Region M. De Santiago | 6900941 | Chile | Details | |
| Centro de Oncología de Precisión ( Site 0515) | Santiago | Region M. De Santiago | 7560908 | Chile | Details | |
| Bradfordhill ( Site 0510) | Santiago | Region M. De Santiago | 8420383 | Chile | Details | |
| ONCOCENTRO APYS-ACEREY ( Site 0503) | Viña del Mar | Valparaiso | 2520598 | Chile | Details | |
| Centro de Investigación Oncológica del Norte ( Site 0504) | Antofagasta | 1240000 | Chile | Details | ||
| Anhui Provincil Hospital South District-Respiratory Medicine Dept ( Site 2619) | Hefei | Anhui | 230036 | China | Details | |
| Beijing Cancer hospital-Thoracic Cancer Department A ( Site 2602) | Beijing | Beijing | 100142 | China | Details | |
| Fujian Provincial Cancer Hospital-oncology department ( Site 2621) | Fuzhou | Fujian | 350014 | China | Details | |
| The First Affiliated hospital of Xiamen University ( Site 2626) | Xiamen City | Fujian | 361003 | China | Details | |
| Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( | Guangzhou | Guangdong | 510515 | China | Details | |
| Harbin Medical University Cancer Hospital-oncology of department ( Site 2604) | Harbin | Heilongjiang | 150000 | China | Details | |
| Henan Cancer Hospital ( Site 2608) | Zhengzhou | Henan | 450000 | China | Details | |
| Wuhan Union Hospital Cancer Center-Cancer Center ( Site 2618) | Wuhan | Hubei | 430022 | China | Details | |
| Tongji Hospital Tongji Medical,Science & Technology ( Site 2617) | Wuhan | Hubei | 430030 | China | Details | |
| Xiangya Hospital Central South University-Oncology department ( Site 2627) | Changsha | Hunan | 410008 | China | Details | |
| The Second Xiangya Hospital of Central South University ( Site 2623) | Changsha | Hunan | 410011 | China | Details | |
| Hunan Cancer Hospital ( Site 2622) | Changsha | Hunan | 410013 | China | Details | |
| Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Oncology ( | Nanjing | Jiangsu | 210000 | China | Details | |
| The First Affiliated Hospital of Nanchang University-Respiratory Medicine Department ( Site 2625) | Nanchang | Jiangxi | 330006 | China | Details | |
| The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2624) | Nanchang | Jiangxi | 330006 | China | Details | |
| Jilin Cancer Hospital-oncology department ( Site 2603) | Changchun | Jilin | 132000 | China | Details | |
| The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 2607) | Xi'an | Shaanxi | 710061 | China | Details | |
| Shandong Cancer Hospital-Oncology Department ( Site 2630) | Jinan | Shandong | 250117 | China | Details | |
| Fudan University Shanghai Cancer Center ( Site 2616) | Shanghai | Shanghai | 200032 | China | Details | |
| Shanghai Pulmonary Hospital-Oncology Department ( Site 2601) | Shanghai | Shanghai | 200433 | China | Details | |
| West China Hospital of Sichuan University ( Site 2610) | Cheng Du | Sichuan | 610041 | China | Details | |
| Sichuan Cancer hospital ( Site 2628) | Chengdu | Sichuan | 610041 | China | Details | |
| The Second People's Hospital of Yibin ( Site 2629) | Yibin | Sichuan | 644000 | China | Details | |
| Tianjin Medical University Cancer Institute and Hospital-lung cancer ( Site 2606) | Tianjin | Tianjin | 300060 | China | Details | |
| The First Affiliated Hospital, Zhejiang University-Respiratory Department ( Site 2613) | Hangzhou | Zhejiang | 310003 | China | Details | |
| Sir Run Run Shaw Hospital-Medical Oncology ( Site 2615) | Hangzhou | Zhejiang | 310016 | China | Details | |
| Zhejiang Cancer Hospital-Oncology ( Site 2612) | Hangzhou | Zhejiang | 310022 | China | Details | |
| The Second Affiliated hospital of Zhejiang University school of medicine-Respiratory Medicine ( Site | Hangzhou | Zhejiang | 310052 | China | Details | |
| Fundación Colombiana de Cancerología Clínica Vida ( Site 0603) | Medellin | Antioquia | 050030 | Colombia | Details | |
| Sociedad De Oncologia Y Hematologia Del Cesar ( Site 0606) | Valledupar | Cesar | 200001 | Colombia | Details | |
| Oncomedica S.A.-Oncomedica S.A ( Site 0609) | Montería | Cordoba | 230001 | Colombia | Details | |
| Administradora Country S.A. - Clinica del Country ( Site 0601) | Bogotá | Distrito Capital De Bogota | 110221 | Colombia | Details | |
| Oncologos del Occidente ( Site 0608) | Pereira | Risaralda | 660001 | Colombia | Details | |
| CENTRE HOSPITALIER REGIONAL D'ORLEANS-Service de Pneumologie ( Site 0806) | Orléans | Centre | 45067 | France | Details | |
| Centre Hospitalier d'Annecy ( Site 0807) | Epagny Metz-Tessy | Haute-Savoie | 74370 | France | Details | |
| Institut de Cancérologie de l'Ouest ( Site 0802) | ANGERS cedex 02 | Maine-et-Loire | 49055 | France | Details | |
| Centre Hospitalier Regional Universitaire de Lille - Hôpital-Service de pneumologie et oncologie th | Lille | Nord-Pas-de-Calais | 59037 | France | Details | |
| CENTRE LEON BERARD ( Site 0803) | Lyon CEDEX 08 | Rhone | 69373 | France | Details | |
| HIA Sainte Anne ( Site 0804) | Toulon | Var | 83800 Cedex 9 | France | Details | |
| Centre Hospitalier d'Avignon ( Site 0810) | Avignon | Vaucluse | 84000 | France | Details | |
| UKGM Gießen/Marburg-Medical Clinic V ( Site 0912) | Gießen | Hessen | 35392 | Germany | Details | |
| GEFOS Gesellschaft f. onkologische Studien ( Site 0909) | Dortmund | Nordrhein-Westfalen | 44263 | Germany | Details | |
| Universitätsklinikum Schleswig-Holstein-Pneumologie ( Site 0902) | Lübeck | Schleswig-Holstein | 23538 | Germany | Details | |
| SRH Wald-Klinikum Gera ( Site 0911) | Gera | Thuringen | 07548 | Germany | Details | |
| Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 0913 | Berlin | 13353 | Germany | Details | ||
| Rambam Health Care Campus-Oncology ( Site 1303) | Haifa | 3109601 | Israel | Details | ||
| Shaare Zedek Medical Center-Oncology ( Site 1306) | Jerusalem | 9013102 | Israel | Details | ||
| Meir Medical Center-oncology ( Site 1301) | Kfar Saba | 4428164 | Israel | Details | ||
| Sheba Medical Center-ONCOLOGY ( Site 1302) | Ramat Gan | 5265601 | Israel | Details | ||
| Sourasky Medical Center-Oncology ( Site 1305) | Tel Aviv | 6423906 | Israel | Details | ||
| National Hospital Organization Shikoku Cancer Center ( Site 2414) | Matsuyama | Ehime | 791-0280 | Japan | Details | |
| Ehime University Hospital ( Site 2411) | Toon | Ehime | 791-0295 | Japan | Details | |
| Hyogo Cancer Center-Thoracic Oncology ( Site 2409) | Akashi | Hyogo | 673-8558 | Japan | Details | |
| Kanazawa University Hospital ( Site 2407) | Kanazawa | Ishikawa | 920-8641 | Japan | Details | |
| Kanagawa cancer center-Department of Thoracic Oncology ( Site 2405) | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
| Miyagi Cancer Center ( Site 2401) | Natori | Miyagi | 981-1293 | Japan | Details | |
| Kansai Medical University Hospital ( Site 2415) | Hirakata | Osaka | 573-1191 | Japan | Details | |
| Saitama Prefectural Cancer Center ( Site 2406) | Ina-machi | Saitama | 362-0806 | Japan | Details | |
| Shizuoka Cancer Center ( Site 2408) | Nagaizumi | Shizuoka | 411-8777 | Japan | Details | |
| Japanese Foundation for Cancer Research ( Site 2402) | Koto | Tokyo | 135-8550 | Japan | Details | |
| Showa University Hospital ( Site 2403) | Shinagawa | Tokyo | 1428666 | Japan | Details | |
| National Hospital Organization Kyushu Medical Center ( Site 2413) | Fukuoka | 810-8563 | Japan | Details | ||
| National Hospital Organization Kyushu Cancer Center ( Site 2412) | Fukuoka | 811-1395 | Japan | Details | ||
| Okayama University Hospital ( Site 2410) | Okayama | 700-8558 | Japan | Details | ||
| Nippon Medical School Hospital ( Site 2404) | Tokyo | 113-8603 | Japan | Details | ||
| Chonnam National University Hwasun Hospital-Pulmonology ( Site 2201) | Hwasun | Jeonranamdo | 58128 | Korea, Republic of | Details | |
| Pusan National University Hospital ( Site 2205) | Busan | Pusan-Kwangyokshi | 49241 | Korea, Republic of | Details | |
| Asan Medical Center ( Site 2206) | Songpa-gu | Seoul | 05505 | Korea, Republic of | Details | |
| Kyungpook National University Chilgok Hospital-Pulmonology ( Site 2202) | Deagu | Taegu-Kwangyokshi | 41404 | Korea, Republic of | Details | |
| Chungnam national university hospital-Department of Internal Medicine ( Site 2203) | Daejeon | Taejon-Kwangyokshi | 35015 | Korea, Republic of | Details | |
| Korea University Guro Hospital-Internal Medicine ( Site 2204) | Seoul | Korea, Republic of | Details | |||
| CENTRO DE INFUSION E INVESTIGACION ONCOLOGIA DE SALTILLO S.C. ( Site 0304) | Saltillo | Coahuila | 25279 | Mexico | Details | |
| Alivia Clínica de Alta Especialidad ( Site 0310) | Ciudad de Mexico | Distrito Federal | 06760 | Mexico | Details | |
| Arké SMO S.A. de C.V. ( Site 0301) | Mexico | Distrito Federal | 06700 | Mexico | Details | |
| Hospital Civil Fray Antonio Alcalde ( Site 0307) | Guadalajara | Jalisco | 44280 | Mexico | Details | |
| Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1903) | Bydgoszcz | Kujawsko-pomorskie | 85-796 | Poland | Details | |
| Centrum Medyczne Ostrobramska NZOZ Magodent ( Site 1908) | Warsaw | Mazowieckie | 04-125 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1904) | Przemysl | Podkarpackie | 37-700 | Poland | Details | |
| Szpital Specjalistyczny w Prabutach Spolka z o.o. ( Site 1906) | Prabuty | Pomorskie | 82-550 | Poland | Details | |
| Centrum Pulmonologii i Torakochirurgii w Bystrej ( Site 1907) | Bystra | Slaskie | 43-360 | Poland | Details | |
| Przychodnia Lekarska KOMED ( Site 1902) | Konin | Wielkopolskie | 62-500 | Poland | Details | |
| Med-Polonia Sp. z o. o. ( Site 1909) | Poznan | Wielkopolskie | 60-693 | Poland | Details | |
| CHUAC-Hospital Teresa Herrera-MEDICAL ONCOLOGY ( Site 1106) | A Coruña | La Coruna | 15006 | Spain | Details | |
| Hospital Insular de Gran Canaria-Oncology ( Site 1102) | Las Palmas de Gran Canaria | Las Palmas | 35001 | Spain | Details | |
| Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1101) | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinico San Carlos-Oncology Department ( Site 1107) | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 1103) | Sevilla | 41009 | Spain | Details | ||
| Hospital Clínico Universitario Lozano Blesa-Oncology ( Site 1105) | Zaragoza | 50009 | Spain | Details | ||
| Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 2254) | Kaohsiung | 807 | Taiwan | Details | ||
| China Medical University Hospital ( Site 2253) | Taichung | 40447 | Taiwan | Details | ||
| NATIONAL CHENG-KUNG UNI. HOSP. ( Site 2252) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital-Oncology ( Site 2255) | Taipei | 100 | Taiwan | Details | ||
| Chang Gung Medical Foundation-Linkou Branch ( Site 2251) | Taoyuan | 333 | Taiwan | Details | ||
| Faculty of Medicine - Khon Kaen University ( Site 2303) | Muang | Khon Kaen | 40002 | Thailand | Details | |
| Faculty of Medicine Siriraj Hospital ( Site 2304) | Bangkok | Krung Thep Maha Nakhon | 10700 | Thailand | Details | |
| Chulabhorn Hospital ( Site 2305) | Lak Si | Krung Thep Maha Nakhon | 10210 | Thailand | Details | |
| Songklanagarind hospital ( Site 2302) | Hatyai | Songkhla | 90110 | Thailand | Details | |
| Maharaj Nakorn Chiang Mai Hospital-Chiang Mai Clinical Trial Unit (CM-CTU) ( Site 2301) | Chiang Mai | 50200 | Thailand | Details | ||
| Acibadem Altunizade Hospital-Oncology ( Site 1207) | Üsküdar / Stanbul | Istanbul | 34662 | Turkey | Details | |
| Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1208) | Adana | 01250 | Turkey | Details | ||
| Hacettepe Universitesi-oncology hospital ( Site 1202) | Ankara | 06230 | Turkey | Details | ||
| Liv Hospital Ankara-Oncology ( Site 1205) | Ankara | 06680 | Turkey | Details | ||
| Ankara City Hospital ( Site 1204) | Ankara | 06800 | Turkey | Details | ||
| Trakya University-Medical Oncology ( Site 1203) | Edirne | 22030 | Turkey | Details | ||
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1209) | Istanbul | 34722 | Turkey | Details | ||
| Umraniye Training and Research Hospital-medical oncology ( Site 1206) | Istanbul | 34766 | Turkey | Details | ||
| Leicester Royal Infirmary-HOPE Clinical Trials Unit ( Site 1502) | Leicester | England | United Kingdom | Details | ||
| Chelsea and Westminster Hospital NHS Foundation Trust-Research and Development ( Site 1501) | London | England | SW10 9NH | United Kingdom | Details | |
| University College London Hospital-Cancer Clinical Trials Unit ( Site 1509) | London-Camden | London, City Of | NW1 2PG | United Kingdom | Details | |
| St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1506) | London | London, City Of | EC1A 7BE | United Kingdom | Details |