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| NCT ID | NCT05261399 |
| Title | Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment (SAFFRON) |
| Acronym | SAFFRON |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | POL | NLD | ITA | ISR | GRC | GBR | FRA | ESP | DEU | CHE | CAN | BRA | BGR | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | NOT_YET_RECRUITING | La Jolla | California | 92093 | United States | Details |
| Research Site | RECRUITING | Orange City | Florida | 32763 | United States | Details |
| Research Site | RECRUITING | Orlando | Florida | 32804 | United States | Details |
| Research Site | RECRUITING | Honolulu | Hawaii | 96819 | United States | Details |
| Research Site | WITHDRAWN | Evergreen Park | Illinois | 60805 | United States | Details |
| Research Site | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Research Site | WITHDRAWN | Boston | Massachusetts | 02215 | United States | Details |
| Research Site | WITHDRAWN | Detroit | Michigan | 48202 | United States | Details |
| Research Site | WITHDRAWN | Florham Park | New Jersey | 07932 | United States | Details |
| Research Site | RECRUITING | New Brunswick | New Jersey | 08903 | United States | Details |
| Research Site | RECRUITING | New York | New York | 10032 | United States | Details |
| Research Site | WITHDRAWN | Canton | Ohio | 44718 | United States | Details |
| Research Site | RECRUITING | Nashville | Tennessee | 37232 | United States | Details |
| Research Site | RECRUITING | Berazategui | B1884BBF | Argentina | Details | |
| Research Site | RECRUITING | Buenos Aires | C1125ABD | Argentina | Details | |
| Research Site | RECRUITING | Caba | C1019ABS | Argentina | Details | |
| Research Site | NOT_YET_RECRUITING | Cordoba | X5004APD | Argentina | Details | |
| Research Site | RECRUITING | Florida | B1602DQD | Argentina | Details | |
| Research Site | RECRUITING | La Rioja | F5300COE | Argentina | Details | |
| Research Site | RECRUITING | Rosario | 2000 | Argentina | Details | |
| Research Site | RECRUITING | Rosario | 2123 | Argentina | Details | |
| Research Site | RECRUITING | San Miguel de Tucumán | 4000 | Argentina | Details | |
| Research Site | RECRUITING | Viedma | R8500ACE | Argentina | Details | |
| Research Site | RECRUITING | Clayton | 3168 | Australia | Details | |
| Research Site | RECRUITING | Fremantle | 6160 | Australia | Details | |
| Research Site | WITHDRAWN | Geelong | 3220 | Australia | Details | |
| Research Site | RECRUITING | Liverpool | 2170 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Southport | 4215 | Australia | Details | |
| Research Site | RECRUITING | Waratah NSW | 2298 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Westmead | 2145 | Australia | Details | |
| Research Site | WITHDRAWN | Graz | 8036 | Austria | Details | |
| Research Site | RECRUITING | Salzburg | 5020 | Austria | Details | |
| Research Site | WITHDRAWN | Wien | 1140 | Austria | Details | |
| Research Site | RECRUITING | Bruxelles | 1000 | Belgium | Details | |
| Research Site | WITHDRAWN | Bruxelles | 1200 | Belgium | Details | |
| Research Site | RECRUITING | Edegem | B-2650 | Belgium | Details | |
| Research Site | RECRUITING | Gent | 9000 | Belgium | Details | |
| Research Site | RECRUITING | Hasselt | 3500 | Belgium | Details | |
| Research Site | RECRUITING | Mons | 7000 | Belgium | Details | |
| Research Site | RECRUITING | Roeselare | 8800 | Belgium | Details | |
| Research Site | RECRUITING | Sint-Niklaas | 9100 | Belgium | Details | |
| Research Site | RECRUITING | Belo Horizonte | 30110-022 | Brazil | Details | |
| Research Site | RECRUITING | Brasilia | 70390-700 | Brazil | Details | |
| Research Site | RECRUITING | Cachoeiro de Itapemirim | 29308-014 | Brazil | Details | |
| Research Site | RECRUITING | Curitiba | 80810-050 | Brazil | Details | |
| Research Site | RECRUITING | Ijuí | 98700-000 | Brazil | Details | |
| Research Site | RECRUITING | Ipatinga | 35162-189 | Brazil | Details | |
| Research Site | RECRUITING | Porto Alegre | 90035-903 | Brazil | Details | |
| Research Site | RECRUITING | Porto Alegre | 90050-170 | Brazil | Details | |
| Research Site | RECRUITING | Porto Alegre | 90540-140 | Brazil | Details | |
| Research Site | RECRUITING | Rio De Janeiro | 20231-050 | Brazil | Details | |
| Research Site | RECRUITING | Rio De Janeiro | 22793-080 | Brazil | Details | |
| Research Site | RECRUITING | Salvador | 41253-190 | Brazil | Details | |
| Research Site | RECRUITING | Salvador | 41950-610 | Brazil | Details | |
| Research Site | RECRUITING | São Paulo | 04014-002 | Brazil | Details | |
| Research Site | RECRUITING | São Paulo | 04538-132 | Brazil | Details | |
| Research Site | RECRUITING | São Paulo | 04556-100 | Brazil | Details | |
| Research Site | RECRUITING | Vitória | 29043-260 | Brazil | Details | |
| Research Site | RECRUITING | Haskovo | 6300 | Bulgaria | Details | |
| Research Site | RECRUITING | Pleven | 5800 | Bulgaria | Details | |
| Research Site | RECRUITING | Plovdiv | 4002 | Bulgaria | Details | |
| Research Site | WITHDRAWN | Sofia | 1407 | Bulgaria | Details | |
| Research Site | WITHDRAWN | Varna | 9010 | Bulgaria | Details | |
| Research Site | RECRUITING | Vratsa | 3000 | Bulgaria | Details | |
| Research Site | NOT_YET_RECRUITING | Calgary | Alberta | T2N 4N2 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Mississauga | Ontario | L5M 2N1 | Canada | Details |
| Research Site | RECRUITING | Toronto | Ontario | M4N 3M5 | Canada | Details |
| Research Site | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Research Site | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Research Site | RECRUITING | Montreal | Quebec | H3T 1M5 | Canada | Details |
| Research Site | RECRUITING | Santiago | 7500000 | Chile | Details | |
| Research Site | RECRUITING | Santiago | 7500713 | Chile | Details | |
| Research Site | RECRUITING | Temuco | 4800827 | Chile | Details | |
| Research Site | RECRUITING | Baoding | 71030 | China | Details | |
| Research Site | RECRUITING | Beijing | 100036 | China | Details | |
| Research Site | RECRUITING | Beijing | 101149 | China | Details | |
| Research Site | RECRUITING | Bengbu | 233060 | China | Details | |
| Research Site | RECRUITING | Changchun | 130012 | China | Details | |
| Research Site | RECRUITING | Changsha | 410011 | China | Details | |
| Research Site | WITHDRAWN | Changsha | 410013 | China | Details | |
| Research Site | RECRUITING | Changsha | 41003 | China | Details | |
| Research Site | RECRUITING | Chengdu | 610041 | China | Details | |
| Research Site | RECRUITING | Chongqing | 400016 | China | Details | |
| Research Site | RECRUITING | Fuzhou | 350001 | China | Details | |
| Research Site | RECRUITING | Fuzhou | 350011 | China | Details | |
| Research Site | RECRUITING | Hangzhou | 310022 | China | Details | |
| Research Site | RECRUITING | Hankou,Wuhan | 430022 | China | Details | |
| Research Site | RECRUITING | Harbin | 150040 | China | Details | |
| Research Site | RECRUITING | Hefei | 230031 | China | Details | |
| Research Site | RECRUITING | Jinan | 250022 | China | Details | |
| Research Site | RECRUITING | Linyi | 276000 | China | Details | |
| Research Site | RECRUITING | Nanchang | 330006 | China | Details | |
| Research Site | RECRUITING | Qingdao | 266035 | China | Details | |
| Research Site | RECRUITING | Shanghai | 200030 | China | Details | |
| Research Site | RECRUITING | Shenyang | 110001 | China | Details | |
| Research Site | RECRUITING | Shenzhen | 518020 | China | Details | |
| Research Site | RECRUITING | Wuhan | 430079 | China | Details | |
| Research Site | RECRUITING | Xi'an | 710061 | China | Details | |
| Research Site | RECRUITING | Xiangfan | 441021 | China | Details | |
| Research Site | RECRUITING | Xian | 710100 | China | Details | |
| Research Site | RECRUITING | Yichang | 443003 | China | Details | |
| Research Site | RECRUITING | Zhengzhou | 450008 | China | Details | |
| Research Site | RECRUITING | Angers | 49933 | France | Details | |
| Research Site | RECRUITING | Bobigny | 93000 | France | Details | |
| Research Site | RECRUITING | Bordeaux Cedex | 33076 | France | Details | |
| Research Site | RECRUITING | Brest | 29200 | France | Details | |
| Research Site | RECRUITING | Creteil | 94010 | France | Details | |
| Research Site | RECRUITING | Dijon | 21079 | France | Details | |
| Research Site | RECRUITING | Marseille | 13915 | France | Details | |
| Research Site | WITHDRAWN | Montpellier | 34298 | France | Details | |
| Research Site | RECRUITING | Paris | 75005 | France | Details | |
| Research Site | RECRUITING | Paris | 75018 | France | Details | |
| Research Site | RECRUITING | Poitiers | 86021 | France | Details | |
| Research Site | RECRUITING | Rennes | 35033 | France | Details | |
| Research Site | RECRUITING | Rouen | 76000 | France | Details | |
| Research Site | RECRUITING | Saint-Herblain | 44800 | France | Details | |
| Research Site | RECRUITING | Saint-Quentin | 02321 | France | Details | |
| Research Site | RECRUITING | Strasbourg Cedex | 67091 | France | Details | |
| Research Site | RECRUITING | Suresnes Cedex | 92151 | France | Details | |
| Research Site | RECRUITING | Berlin | 13353 | Germany | Details | |
| Research Site | RECRUITING | Berlin | 14165 | Germany | Details | |
| Research Site | RECRUITING | Chemnitz | 09113 | Germany | Details | |
| Research Site | RECRUITING | Frankfurt A. Main | 60590 | Germany | Details | |
| Research Site | RECRUITING | Gauting | 82131 | Germany | Details | |
| Research Site | WITHDRAWN | Homburg | 66424 | Germany | Details | |
| Research Site | RECRUITING | Immenhausen | 34376 | Germany | Details | |
| Research Site | RECRUITING | Löwenstein | 74245 | Germany | Details | |
| Research Site | RECRUITING | Muenster | 48149 | Germany | Details | |
| Research Site | RECRUITING | München | 81925 | Germany | Details | |
| Research Site | WITHDRAWN | Stuttgart | 70376 | Germany | Details | |
| Research Site | RECRUITING | Wangen | 88239 | Germany | Details | |
| Research Site | RECRUITING | Athens | 115 27 | Greece | Details | |
| Research Site | RECRUITING | Athens | 11527 | Greece | Details | |
| Research Site | RECRUITING | Chaidari | 124 62 | Greece | Details | |
| Research Site | RECRUITING | Heraklion | 71110 | Greece | Details | |
| Research Site | RECRUITING | Larissa | 41110 | Greece | Details | |
| Research Site | RECRUITING | Rio | 265 04 | Greece | Details | |
| Research Site | RECRUITING | Thessaloniki | 546 39 | Greece | Details | |
| Research Site | RECRUITING | Thessaloniki | 54622 | Greece | Details | |
| Research Site | RECRUITING | HKG | 999077 | Hong Kong | Details | |
| Research Site | RECRUITING | Hong Kong | Hong Kong | Details | ||
| Research Site | RECRUITING | Kowloon | Hong Kong | Details | ||
| Research Site | RECRUITING | Afula | 18341 | Israel | Details | |
| Research Site | RECRUITING | Ashdod | 7747629 | Israel | Details | |
| Research Site | RECRUITING | Be'er Ya'akov | 70300 | Israel | Details | |
| Research Site | RECRUITING | Hadera | 38100 | Israel | Details | |
| Research Site | RECRUITING | Jerusalem | 91031 | Israel | Details | |
| Research Site | RECRUITING | Tel Aviv | 6423906 | Israel | Details | |
| Research Site | RECRUITING | Avellino | 83100 | Italy | Details | |
| Research Site | RECRUITING | Aviano | 33081 | Italy | Details | |
| Research Site | RECRUITING | Catania | 95123 | Italy | Details | |
| Research Site | RECRUITING | Meldola | 47014 | Italy | Details | |
| Research Site | RECRUITING | Milano | 20133 | Italy | Details | |
| Research Site | RECRUITING | Milan | 20141 | Italy | Details | |
| Research Site | RECRUITING | Modena | 41124 | Italy | Details | |
| Research Site | RECRUITING | Monserrato | 09042 | Italy | Details | |
| Research Site | RECRUITING | Napoli | 80138 | Italy | Details | |
| Research Site | RECRUITING | Orbassano | 10043 | Italy | Details | |
| Research Site | RECRUITING | Padova | 35128 | Italy | Details | |
| Research Site | RECRUITING | Parma | 43126 | Italy | Details | |
| Research Site | RECRUITING | Perugia | 6124 | Italy | Details | |
| Research Site | RECRUITING | Peschiera Del Garda | 37019 | Italy | Details | |
| Research Site | RECRUITING | Roma | 00144 | Italy | Details | |
| Research Site | RECRUITING | Roma | 00152 | Italy | Details | |
| Research Site | RECRUITING | Treviso | 31100 | Italy | Details | |
| Research Site | RECRUITING | Bunkyo-ku | 113-8603 | Japan | Details | |
| Research Site | RECRUITING | Chuo-ku | 104-0045 | Japan | Details | |
| Research Site | RECRUITING | Fukuoka-shi | 812-8582 | Japan | Details | |
| Research Site | RECRUITING | Hirosaki-shi | 036-8563 | Japan | Details | |
| Research Site | RECRUITING | Hiroshima-shi | 730-8518 | Japan | Details | |
| Research Site | RECRUITING | Iwakuni-shi | 740-8510 | Japan | Details | |
| Research Site | RECRUITING | Kanazawa-shi | 920-8641 | Japan | Details | |
| Research Site | RECRUITING | Kashiwa | 277-8577 | Japan | Details | |
| Research Site | RECRUITING | Kobe-shi | 650-0017 | Japan | Details | |
| Research Site | RECRUITING | Kobe | 650-0046 | Japan | Details | |
| Research Site | RECRUITING | Kumamoto-shi | 860-8556 | Japan | Details | |
| Research Site | RECRUITING | Kurume-shi | 830-0011 | Japan | Details | |
| Research Site | WITHDRAWN | Matsuyama | 791-0288 | Japan | Details | |
| Research Site | RECRUITING | Nagasaki-shi | 852-8501 | Japan | Details | |
| Research Site | RECRUITING | Okayama-shi | 700-8558 | Japan | Details | |
| Research Site | RECRUITING | Osaka-shi | 534-0021 | Japan | Details | |
| Research Site | RECRUITING | Osakasayama-shi | 589-8511 | Japan | Details | |
| Research Site | RECRUITING | Sakai-shi | 591-8555 | Japan | Details | |
| Research Site | RECRUITING | Sapporo-shi | 003-0804 | Japan | Details | |
| Research Site | RECRUITING | Sapporo-shi | 060-8638 | Japan | Details | |
| Research Site | RECRUITING | Sendai-shi | 980-0873 | Japan | Details | |
| Research Site | RECRUITING | Sunto-gun | 411-8777 | Japan | Details | |
| Research Site | RECRUITING | Utsunomiya-shi | 320-0834 | Japan | Details | |
| Research Site | RECRUITING | Wakayama-shi | 641-8510 | Japan | Details | |
| Research Site | RECRUITING | Yokohama-shi | 241-8515 | Japan | Details | |
| Research Site | RECRUITING | Goyang-si | 10408 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Gyeonggi-do | 13620 | Korea, Republic of | Details | |
| Research Site | NOT_YET_RECRUITING | Incheon | 21431 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Jinju-si | 660-702 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Seoul | 06273 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Research Site | NOT_YET_RECRUITING | Seoul | 08308 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Seoul | 138-736 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Seoul | 6591 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Suwon | 16247 | Korea, Republic of | Details | |
| Research Site | WITHDRAWN | Ulsan | 44033 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Kota Bharu | 15586 | Malaysia | Details | |
| Research Site | RECRUITING | Kuala Lumpur | 59100 | Malaysia | Details | |
| Research Site | RECRUITING | Petaling Jaya | 47500 | Malaysia | Details | |
| Research Site | RECRUITING | Pulau Pinang | 10990 | Malaysia | Details | |
| Research Site | RECRUITING | Sabah | 88996 | Malaysia | Details | |
| Research Site | WITHDRAWN | Amsterdam | 1066CX | Netherlands | Details | |
| Research Site | RECRUITING | Bacolod | 6100 | Philippines | Details | |
| Research Site | NOT_YET_RECRUITING | Baguio City | 2600 | Philippines | Details | |
| Research Site | NOT_YET_RECRUITING | Cebu City | 6000 | Philippines | Details | |
| Research Site | RECRUITING | Cebu | 6000 | Philippines | Details | |
| Research Site | RECRUITING | Davao City | 8000 | Philippines | Details | |
| Research Site | NOT_YET_RECRUITING | Manila | 1000 | Philippines | Details | |
| Research Site | RECRUITING | Quezon City | 1100 | Philippines | Details | |
| Research Site | RECRUITING | Quezon City | 1104 | Philippines | Details | |
| Research Site | NOT_YET_RECRUITING | Quezon City | 1112 | Philippines | Details | |
| Research Site | RECRUITING | San Juan | 1502 | Philippines | Details | |
| Research Site | RECRUITING | Bialystok | 15-003 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Krakow | 30-727 | Poland | Details | |
| Research Site | RECRUITING | Olsztyn | 10-357 | Poland | Details | |
| Research Site | RECRUITING | Łódź | 93-338 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Chelyabinsk | 454087 | Russian Federation | Details | |
| Research Site | WITHDRAWN | Moscow | 119881 | Russian Federation | Details | |
| Research Site | WITHDRAWN | Saint Petersburg | 197022 | Russian Federation | Details | |
| Research Site | NOT_YET_RECRUITING | Tomsk | 634050 | Russian Federation | Details | |
| Research Site | RECRUITING | Singapore | 169610 | Singapore | Details | |
| Research Site | RECRUITING | Singapore | 308433 | Singapore | Details | |
| Research Site | RECRUITING | Badajoz | 6006 | Spain | Details | |
| Research Site | RECRUITING | Badalona | 8916 | Spain | Details | |
| Research Site | RECRUITING | Barcelona | 08036 | Spain | Details | |
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| Research Site | RECRUITING | Cordoba | 14004 | Spain | Details | |
| Research Site | RECRUITING | Girona | 17007 | Spain | Details | |
| Research Site | RECRUITING | La Coruña | 15006 | Spain | Details | |
| Research Site | RECRUITING | Madrid | 28040 | Spain | Details | |
| Research Site | WITHDRAWN | Madrid | 28040 | Spain | Details | |
| Research Site | RECRUITING | Madrid | 28041 | Spain | Details | |
| Research Site | RECRUITING | Majadahonda | 28222 | Spain | Details | |
| Research Site | RECRUITING | Málaga | 29010 | Spain | Details | |
| Research Site | RECRUITING | Pontevedra | 36312 | Spain | Details | |
| Research Site | RECRUITING | Sabadell | 08208 | Spain | Details | |
| Research Site | RECRUITING | Sevilla | 41009 | Spain | Details | |
| Research Site | RECRUITING | Valencia | 46026 | Spain | Details | |
| Research Site | RECRUITING | Zaragoza | 50009 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Baden | CH-5405 | Switzerland | Details | |
| Research Site | RECRUITING | Basel | 4031 | Switzerland | Details | |
| Research Site | NOT_YET_RECRUITING | Bern | 3010 | Switzerland | Details | |
| Research Site | WITHDRAWN | Winterthur | 8401 | Switzerland | Details | |
| Research Site | RECRUITING | Zürich | 8063 | Switzerland | Details | |
| Research Site | RECRUITING | Chiayi | 62247 | Taiwan | Details | |
| Research Site | RECRUITING | Hsinchu | 300 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Kaohsiung City | 83301 | Taiwan | Details | |
| Research Site | RECRUITING | Liuying | 736 | Taiwan | Details | |
| Research Site | RECRUITING | Taichung | 404 | Taiwan | Details | |
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| Research Site | RECRUITING | Taipei City | 11259 | Taiwan | Details | |
| Research Site | RECRUITING | Taipei | 100 | Taiwan | Details | |
| Research Site | RECRUITING | Bangkok | 10210 | Thailand | Details | |
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| Research Site | RECRUITING | Chiang Mai | 50200 | Thailand | Details | |
| Research Site | RECRUITING | Dusit | 10300 | Thailand | Details | |
| Research Site | RECRUITING | Hat Yai | 90110 | Thailand | Details | |
| Research Site | RECRUITING | Muang | 40002 | Thailand | Details | |
| Research Site | RECRUITING | Mueang Chanthaburi | 22000 | Thailand | Details | |
| Research Site | RECRUITING | Adana | 1370 | Turkey | Details | |
| Research Site | RECRUITING | Ankara | 6800 | Turkey | Details | |
| Research Site | RECRUITING | Edirne | 22030 | Turkey | Details | |
| Research Site | RECRUITING | Istanbul | 34214 | Turkey | Details | |
| Research Site | RECRUITING | Istanbul | 34722 | Turkey | Details | |
| Research Site | RECRUITING | Izmir | 35100 | Turkey | Details | |
| Research Site | NOT_YET_RECRUITING | Bristol | BS2 8HW | United Kingdom | Details | |
| Research Site | WITHDRAWN | Leicester | LE1 5WW | United Kingdom | Details | |
| Research Site | WITHDRAWN | Liverpool | L7 3EW | United Kingdom | Details | |
| Research Site | RECRUITING | London | SE1 9RT | United Kingdom | Details | |
| Research Site | RECRUITING | Manchester | M20 4BX | United Kingdom | Details | |
| Research Site | WITHDRAWN | Newport | NP10 8FZ | United Kingdom | Details | |
| Research Site | WITHDRAWN | Reading | RG2 9LH | United Kingdom | Details | |
| Research Site | RECRUITING | Wolverhampton | WV10 0QP | United Kingdom | Details | |
| Research Site | RECRUITING | Can Tho | 900000 | Vietnam | Details | |
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| Research Site | RECRUITING | Ho Chi Minh city | 700000 | Vietnam | Details | |
| Research Site | RECRUITING | Ho Chi Minh | 70000 | Vietnam | Details |