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| NCT ID | NCT05298423 |
| Title | Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006/KEYVIBE-006) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | ROU | ITA | ISR | GRC | ESP | DEU | CZE | BRA | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| VA Long Beach Healthcare System ( Site 2831) | Long Beach | California | 90822 | United States | Details | |
| VA West Los Angeles Medical Center ( Site 2808) | Los Angeles | California | 90073 | United States | Details | |
| Millennium Oncology Research Clinic ( Site 2801) | Hollywood | Florida | 33024 | United States | Details | |
| Mid Florida Hematology and Oncology Center ( Site 2800) | Orange City | Florida | 32763 | United States | Details | |
| Moffitt Cancer Center ( Site 2818) | Tampa | Florida | 33612 | United States | Details | |
| University of Chicago Medical Center ( Site 2828) | Chicago | Illinois | 60637 | United States | Details | |
| Franciscan St. Francis Health ( Site 2812) | Indianapolis | Indiana | 46237 | United States | Details | |
| MFSMC-HJWCI ( Site 2804) | Baltimore | Maryland | 21237 | United States | Details | |
| Boston Medical Center ( Site 2829) | Boston | Massachusetts | 02118 | United States | Details | |
| University of Massachusetts Chan Medical School ( Site 2815) | Worcester | Massachusetts | 01655 | United States | Details | |
| University of Missouri Hospital ( Site 2839) | Columbia | Missouri | 65212 | United States | Details | |
| Cox Medical Center North-Cox Medical Center/Hulston Cancer Center/ Radiation Oncology ( Site 2837) | Springfield | Missouri | 65807 | United States | Details | |
| Rutgers Cancer Institute of New Jersey ( Site 2805) | New Brunswick | New Jersey | 08903 | United States | Details | |
| Icahn School of Medicine at Mount Sinai ( Site 2821) | New York | New York | 10029 | United States | Details | |
| White Plains Hospital ( Site 2835) | White Plains | New York | 10601 | United States | Details | |
| Kaiser Permanente Northwest-Central Interstate--Oncology ( Site 2816) | Portland | Oregon | 97227 | United States | Details | |
| Lancaster General Hospital - Ann B Barshinger Cancer Institute ( Site 2827) | Lancaster | Pennsylvania | 17601 | United States | Details | |
| Thomas Jefferson University - Clinical Research Institute ( Site 2813) | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| Millennium Research & Clinical Development ( Site 2811) | Houston | Texas | 77090 | United States | Details | |
| Central Texas Veterans health care-Oncology & Hematology ( Site 2819) | Temple | Texas | 76504 | United States | Details | |
| MultiCare Health System ( Site 2817) | Tacoma | Washington | 98405 | United States | Details | |
| Instituto Médico Río Cuarto ( Site 3600) | Rio Cuarto | Cordoba | X5800 | Argentina | Details | |
| Sanatorio Parque ( Site 3602) | Rosario | Santa Fe | S2000DSV | Argentina | Details | |
| Clinica Adventista Belgrano ( Site 3601) | Caba | C1430EGF | Argentina | Details | ||
| Canberra Hospital ( Site 0010) | Canberra | Australian Capital Territory | 2605 | Australia | Details | |
| Icon Cancer Centre Hobart ( Site 0003) | Hobart | Tasmania | 7000 | Australia | Details | |
| Ballarat Health Services-Medical Oncology ( Site 0002) | Ballarat Central | Victoria | 3350 | Australia | Details | |
| Frankston Hospital-Oncology and Haematology ( Site 0009) | Frankston | Victoria | 3199 | Australia | Details | |
| St Vincent's Hospital-Oncology Clinical Trials ( Site 0005) | Melbourne | Victoria | 3065 | Australia | Details | |
| Hospital Nossa Senhora da Conceição ( Site 0111) | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details | |
| Instituto de Educação, Pesquisa e Gestão em Saúde ( Site 0105) | Rio de Janeiro | 22793-080 | Brazil | Details | ||
| A. C. Camargo Cancer Center-CAPEC ( Site 0102) | Sao Paulo | 01509-010 | Brazil | Details | ||
| James Lind Centro de Investigacion del Cancer ( Site 0202) | Temuco | Araucania | 4800827 | Chile | Details | |
| Biocenter ( Site 0208) | Concepcion | Biobio | 4070196 | Chile | Details | |
| FALP-UIDO ( Site 0205) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
| Centro de Oncología de Precisión ( Site 0209) | Santiago | Region M. De Santiago | 7560908 | Chile | Details | |
| Bradfordhill ( Site 0200) | Santiago | Region M. De Santiago | 8420383 | Chile | Details | |
| ONCOCENTRO APYS-ACEREY ( Site 0203) | Viña del Mar | Valparaiso | 2520598 | Chile | Details | |
| Beijing Cancer hospital-intrathoratic deparmtment II ( Site 0328) | Beijing | Beijing | 100142 | China | Details | |
| Beijing Cancer hospital-Oncology Radiotherapy Department ( Site 0309) | Beijing | Beijing | 100142 | China | Details | |
| Beijing Peking Union Medical College Hospital-pneumology department ( Site 0300) | Beijing | Beijing | 100730 | China | Details | |
| Army Medical Center of People's Liberation Army-Oncology Department ( Site 0321) | Chongqing | Chongqing | 400042 | China | Details | |
| Fujian Medical University Union Hospital-1 Bingfanglou ( Site 0330) | Fuzhou Fujian | Fujian | 350001 | China | Details | |
| Fujian Provincial Cancer Hospital ( Site 0316) | Fuzhou | Fujian | 350014 | China | Details | |
| The First Affiliated hospital of Xiamen University-oncology ( Site 0317) | Xiamen | Fujian | 361003 | China | Details | |
| Southern Medical University Nanfang Hospital-Department of Oncology ( Site 0336) | Guangzhou | Guangdong | 510515 | China | Details | |
| Fourth Hospital of Hebei Medical University ( Site 0331) | Shijiazhuang | Hebei | 050035 | China | Details | |
| Henan Cancer Hospital ( Site 0333) | Zhengzhou | Henan | 450008 | China | Details | |
| Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 0315) | Wuhan | Hubei | 430022 | China | Details | |
| Hubei Cancer Hospital ( Site 0311) | Wuhan | Hubei | 430079 | China | Details | |
| Xiangya Hospital Central South University-Oncology department ( Site 0310) | Changsha | Hunan | 410008 | China | Details | |
| Hunan Cancer Hospital ( Site 0307) | Changsha | Hunan | 410013 | China | Details | |
| The Second Affiliated Hospital of Soochow University ( Site 0314) | Suzhou | Jiangsu | 215004 | China | Details | |
| Affiliated Hospital of Jiangsu University ( Site 0305) | Zhenjiang | Jiangsu | 212001 | China | Details | |
| Jilin Cancer Hospital-oncology department ( Site 0319) | Changchun | Jilin | 130012 | China | Details | |
| Shandong Provincial Hospital ( Site 0326) | Jinan | Shandong | 250001 | China | Details | |
| Qingdao Central Hospital-Endocrinology ( Site 0332) | Qingdao | Shandong | 266042 | China | Details | |
| Shanghai Chest Hospital-Radiotherapy Department ( Site 0306) | Shanghai | Shanghai | 200030 | China | Details | |
| Fudan University Shanghai Cancer Center ( Site 0304) | Shanghai | Shanghai | 200032 | China | Details | |
| Shanghai Pulmonary Hospital-Radiotherapy department ( Site 0335) | Shanghai | Shanghai | 200433 | China | Details | |
| Shanxi Cancer Hospital-Pulmonology ( Site 0322) | Taiyuan | Shanxi | 030013 | China | Details | |
| West China Hospital of Sichuan University ( Site 0324) | Cheng Du | Sichuan | 610041 | China | Details | |
| Tianjin Cancer Hospital ( Site 0329) | Tianjin | Tianjin | 300060 | China | Details | |
| Hangzhou Cancer Hospital-Medical Oncology ( Site 0302) | Hangzhou | Zhejiang | 310002 | China | Details | |
| The Second Affiliated hospital of Zhejiang University school of medicine ( Site 0301) | Hangzhou | Zhejiang | 310009 | China | Details | |
| Zhejiang Cancer Hospital ( Site 0308) | Hangzhou | Zhejiang | 310022 | China | Details | |
| CIMCA ( Site 0501) | San José | San Jose | 10103 | Costa Rica | Details | |
| PROCLINICAL Pharma ( Site 0504) | San José | San Jose | 11303 | Costa Rica | Details | |
| Hospital Metropolitano - Sede Lindora ( Site 0503) | Santa Ana | San Jose | 10903 | Costa Rica | Details | |
| Masarykuv onkologicky ustav ( Site 3500) | Brno | Brno-mesto | 656 53 | Czechia | Details | |
| Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 3502) | Ostrava | Moravskoslezsky Kraj | 708 52 | Czechia | Details | |
| Instituto de Oncologia ( Site 3003) | Santo Domingo | Distrito Nacional | 10102 | Dominican Republic | Details | |
| Onconet ( Site 3002) | Distrito Nacional | Santo Domingo | 10148 | Dominican Republic | Details | |
| Klinikum Chemnitz-Klinik für Innere Medizin IV ( Site 0607) | Chemnitz | Sachsen | 09116 | Germany | Details | |
| LungenClinic Grosshansdorf-Onkologie ( Site 0602) | Grosshansdorf | Schleswig-Holstein | 22927 | Germany | Details | |
| Universitaetsklinikum Schleswig-Holstein Campus Kiel-Medizinische Klinik II, Hämatologie und Onkolo | Kiel | Schleswig-Holstein | 24105 | Germany | Details | |
| Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 0603 | Berlin | 13353 | Germany | Details | ||
| Errikos Dunant Hospital Center-Second Department of Oncology and Clinical Trials Unit ( Site 0703) | Athens | Attiki | 115 26 | Greece | Details | |
| Alexandra General Hospital of Athens-ONCOLOGY DEPT. ( Site 0706) | Athens | Attiki | 115 28 | Greece | Details | |
| Sotiria Thoracic Diseases Hospital of Athens ( Site 0704) | Athens | Attiki | 11527 | Greece | Details | |
| Metropolitan Hospital ( Site 0702) | Athens | Attiki | 185 47 | Greece | Details | |
| General Oncology Hospital of Kifissia "Agioi Anargiroi"-2nd Department of Medical Oncology ( Site 07 | Nea Kifissia | Attiki | 136 77 | Greece | Details | |
| University General Hospital of Heraklion-Internal Medicine-Oncology ( Site 0700) | Heraklion | Irakleio | 715 00 | Greece | Details | |
| European Interbalkan Medical Center ( Site 0701) | Thessaloniki | 57001 | Greece | Details | ||
| Private Practice- Dr. Rixci Augusto Lenin Ramírez ( Site 0802) | Ciudad de Guatemala | 01010 | Guatemala | Details | ||
| MEDI-K ( Site 0807) | Guatemala | 01009 | Guatemala | Details | ||
| Centro Regional de Sub Especialidades Médicas SA ( Site 0801) | Quetzaltenango | 09001 | Guatemala | Details | ||
| Centro Medico Integral De Cancerología (CEMIC) ( Site 0805) | Quetzaltenango | 09002 | Guatemala | Details | ||
| Rambam Health Care Campus-Oncology ( Site 1001) | Haifa | 3109601 | Israel | Details | ||
| Shaare Zedek Medical Center ( Site 1003) | Jerusalem | 9103102 | Israel | Details | ||
| Rabin Medical Center ( Site 1004) | Petah Tikva | 4941492 | Israel | Details | ||
| Sheba Medical Center-ONCOLOGY ( Site 1000) | Ramat Gan | 5265601 | Israel | Details | ||
| Sourasky Medical Center ( Site 1002) | Tel Aviv | 6423906 | Israel | Details | ||
| Istituto Nazionale Tumori IRCCS Fondazione Pascale-Oncologia medica Toraco-Polmonare ( Site 1107) | Napoli | Campania | 80131 | Italy | Details | |
| Policlinico Universitario Campus Bio-Medico-Radiation Oncology ( Site 1101) | Roma | Lazio | 00128 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 1100) | Milan | Lombardia | 20133 | Italy | Details | |
| Ospedale San Gerardo-ASST Monza-Oncologia ( Site 1102) | Monza | Lombardia | 20900 | Italy | Details | |
| Fondazione IRCCS Policlinico San Matteo ( Site 1103) | Pavia | Lombardia | 27100 | Italy | Details | |
| Azienda Ospedaliera Spedali Civili di Brescia ( Site 1105) | Brescia | 25123 | Italy | Details | ||
| Ospedale San Raffaele ( Site 1104) | Milano | 20132 | Italy | Details | ||
| National Hospital Organization Shikoku Cancer Center ( Site 1211) | Matsuyama | Ehime | 791-0280 | Japan | Details | |
| Kurume University Hospital ( Site 1212) | Kurume | Fukuoka | 830-0011 | Japan | Details | |
| Kobe Minimally Invasive Cancer Center ( Site 1210) | Kobe | Hyogo | 650-0046 | Japan | Details | |
| Kanagawa cancer center ( Site 1204) | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
| Miyagi Cancer Center ( Site 1200) | Natori | Miyagi | 981-1293 | Japan | Details | |
| Sendai Kousei Hospital ( Site 1213) | Sendai | Miyagi | 981-0914 | Japan | Details | |
| Niigata Cancer Center Hospital ( Site 1205) | Niigata-shi | Niigata | 951-8566 | Japan | Details | |
| Kansai Medical University Hospital ( Site 1207) | Hirakata | Osaka | 573-1191 | Japan | Details | |
| Osaka Medical and Pharmaceutical University Hospital ( Site 1208) | Takatsuki | Osaka | 569-8686 | Japan | Details | |
| Saitama Prefectural Cancer Center ( Site 1201) | Ina-machi | Saitama | 362-0806 | Japan | Details | |
| Japanese Foundation for Cancer Research ( Site 1202) | Koto | Tokyo | 135-8550 | Japan | Details | |
| Showa University Hospital ( Site 1203) | Shinagawa | Tokyo | 142-8666 | Japan | Details | |
| Osaka International Cancer Institute ( Site 1209) | Osaka | 541-8567 | Japan | Details | ||
| Chungbuk National University Hospital-Internal medicine ( Site 2400) | Cheongju-si | Chungbuk | 28644 | Korea, Republic of | Details | |
| The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 2401) | Suwon-si | Kyonggi-do | 16247 | Korea, Republic of | Details | |
| Ajou University Hospital-Hematology-Oncology ( Site 2402) | Suwon-si | Kyonggi-do | 16499 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System-Lung Cancer Center ( Site 2403) | Seoul | 03722 | Korea, Republic of | Details | ||
| University Malaya Medical Centre-Clinical Oncology ( Site 1402) | Lembah Pantai | Kuala Lumpur | 59100 | Malaysia | Details | |
| Hospital Pulau Pinang ( Site 1400) | George Town | Pulau Pinang | 10450 | Malaysia | Details | |
| Hospital Kuala Lumpur-Radiotherapy and Oncology ( Site 1401) | Kuala Lumpur | 50586 | Malaysia | Details | ||
| Arké SMO S.A. de C.V. ( Site 1504) | Mexico | Distrito Federal | 06700 | Mexico | Details | |
| Actualidad Basada en la Investigación del Cáncer-Lung Cancer ( Site 1505) | Guadalajara | Jalisco | 44680 | Mexico | Details | |
| Centro Oncologico de Chihuahua-Unidad de Investigacion Clinica ( Site 1507) | Chihuahua | 31217 | Mexico | Details | ||
| Centro de Investigacion Clinica de Oaxaca ( Site 1501) | Oaxaca | 68020 | Mexico | Details | ||
| THE MEDICAL CITY-Cancer Research Center ( Site 3200) | Pasig | National Capital Region | 1605 | Philippines | Details | |
| Veterans Memorial Medical Center-Section of Oncology ( Site 3201) | Quezon City | National Capital Region | 1100 | Philippines | Details | |
| Champalimaud Foundation ( Site 2003) | Lisbon | Lisboa | 1400-038 | Portugal | Details | |
| Hospital CUF Descobertas ( Site 2006) | Lisbon | Lisboa | 1998-018 | Portugal | Details | |
| Unidade Local de Saude de Santo António - Hospital Santo António ( Site 2004) | Porto | 4099-001 | Portugal | Details | ||
| Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 2001) | Porto | 4200-072 | Portugal | Details | ||
| Centrul Medical Medicover Victoria ( Site 2106) | Bucharest | Bucuresti | 010626 | Romania | Details | |
| Amethyst Radiotherapy Center ( Site 2102) | Florești | Cluj | 407280 | Romania | Details | |
| Centrul de Oncologie "Sfântul Nectarie" ( Site 2100) | Craiova | Dolj | 200542 | Romania | Details | |
| Radiology Therapeutic Center ( Site 2108) | Otopeni | Ilfov | 075100 | Romania | Details | |
| Cabinet Medical Oncomed ( Site 2101) | Timisoara | Timis | 300239 | Romania | Details | |
| Centrul Medical Neolife- Baneasa ( Site 2110) | Bucuresti | 077190 | Romania | Details | ||
| CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 2304) | Port Elizabeth | Eastern Cape | 6055 | South Africa | Details | |
| Wilgers Oncology Centre ( Site 2301) | Pretoria | Gauteng | 0040 | South Africa | Details | |
| The Oncology Centre ( Site 2300) | Durban | Kwazulu-Natal | 4091 | South Africa | Details | |
| Abraham Oncology ( Site 2303) | Richards Bay | Kwazulu-Natal | 3900 | South Africa | Details | |
| Cape Town Oncology Trials ( Site 2306) | Cape Town | Western Cape | 7570 | South Africa | Details | |
| Hospital Universitari Vall d'Hebron ( Site 2501) | Barcelona | Cataluna | 08035 | Spain | Details | |
| HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Sit | Barcelona | Cataluna | 08036 | Spain | Details | |
| CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 2502) | Santiago de Compostela | La Coruna | 15706 | Spain | Details | |
| HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 2504) | Pozuelo de Alarcon | Madrid, Comunidad De | 28223 | Spain | Details | |
| Medipol Mega Universite Hastanesi-oncology ( Site 2611) | Stanbul | Istanbul | 34214 | Turkey | Details | |
| Ege University Medicine of Faculty-Chest Diseases Department ( Site 2603) | Bornova | Izmir | 35100 | Turkey | Details | |
| Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 2607) | Adana | 01250 | Turkey | Details | ||
| Ankara Gülhane Eitim ve Aratrma Hastanesi-Oncology ( Site 2602) | Ankara | 06010 | Turkey | Details | ||
| Hacettepe Universitesi-oncology hospital ( Site 2605) | Ankara | 06230 | Turkey | Details | ||
| Memorial Ankara Hastanesi-Medical Oncology ( Site 2609) | Ankara | 06520 | Turkey | Details | ||
| Ankara City Hospital-Medical Oncology ( Site 2601) | Ankara | 06800 | Turkey | Details | ||
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2610) | Istanbul | 34722 | Turkey | Details | ||
| I.E.U. Medical Point Hastanesi-Oncology ( Site 2612) | Izmir | 35575 | Turkey | Details | ||
| Limited Liability Company Ukrainian Center of Tomotherapy-Department of Chemotherapy ( Site 2905) | Kropyvnytskyi | Kirovohradska Oblast | 25011 | Ukraine | Details | |
| Municipal non-profit enterprise "Lviv Territorial Medical Union "Multidisciplinary Clinical Hospital | Lviv | Lvivska Oblast | 79000 | Ukraine | Details | |
| Rivne Regional Clinical Hospital ( Site 2919) | Rivne | Rivnenska Oblast | 33007 | Ukraine | Details | |
| Communal Noncommercial Enterprise "Podillia Regional Oncology Center Of Vinnytsia Regional Council" | Vinnytsia | Vinnytska Oblast | 21029 | Ukraine | Details | |
| Volyn Regional clinical hospital. Regional Medical Oncology Centre. Oncology chemotherapy department | Lutsk | Volynska Oblast | 43018 | Ukraine | Details | |
| Universal Clinic Oberig-Oncology Center ( Site 2916) | Kyiv | 03057 | Ukraine | Details |