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| NCT ID | NCT05306340 |
| Title | A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Genentech, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | ITA | GRC | GBR | ESP | DEU | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alabama Oncology - Bruno Cancer Center | Birmingham | Alabama | 35205 | United States | Details | |
| Alaska Oncology and Hematology | Anchorage | Alaska | 99508 | United States | Details | |
| The Dignity Health Cancer Institute | Phoenix | Arizona | 85004 | United States | Details | |
| Arizona Oncology Associates, PC-CASA | Tucson | Arizona | 85711 | United States | Details | |
| Genesis Cancer Center | Hot Springs | Arkansas | 71913 | United States | Details | |
| University of Arkansas for Medical Sciences; Winthrop Rockefeller Cancer Institute | Little Rock | Arkansas | 72205 | United States | Details | |
| Pacific Cancer Medical Center | Anaheim | California | 92801 | United States | Details | |
| Alta Bates Summit Medical Center; Comprehensive Cancer Center | Berkeley | California | 94704 | United States | Details | |
| Beverly Hills Cancer Center | Beverly Hills | California | 90211 | United States | Details | |
| TOI Clinical Research | Cerritos | California | 90703 | United States | Details | |
| Newport Beach UC Irvine Medical Center | Costa Mesa | California | 92627 | United States | Details | |
| Women's Cancer Care | Fresno | California | 93710 | United States | Details | |
| Scripps Health; Scripps Cancer Center | La Jolla | California | 92037 | United States | Details | |
| Los Angeles Hematology Oncology Medical Group | Los Angeles | California | 90017 | United States | Details | |
| University of California, Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| Emad Ibrahim, Md, Inc | Redlands | California | 92373 | United States | Details | |
| Brian LeBerthon, Med Corp | West Covina | California | 91790-3961 | United States | Details | |
| Yale Cancer Center; Medical Oncology | New Haven | Connecticut | 06520 | United States | Details | |
| Eastern CT Hematology and Oncology Associates | Norwich | Connecticut | 06360-2740 | United States | Details | |
| ASCLEPES Research Centers - Brooksville | Brooksville | Florida | 34613 | United States | Details | |
| Broward Health Medical Center (BHMC) (Broward General Medical Center (BGMC)) | Fort Lauderdale | Florida | 33316 | United States | Details | |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | United States | Details | |
| Orlando Health Cancer Institute | Orlando | Florida | 32806 | United States | Details | |
| Cancer Care Centers of Brevard | Rockledge | Florida | 32955 | United States | Details | |
| Tampa General Hospital | Tampa | Florida | 33606 | United States | Details | |
| Florida Cancer Specialists | West Palm Beach | Florida | 33401 | United States | Details | |
| Piedmont Atlanta Hospital | Atlanta | Georgia | 30309 | United States | Details | |
| Piedmont Fayette Hospital | Fayetteville | Georgia | 30214 | United States | Details | |
| Northwest Georgia Oncology Centers PC - Marietta | Marietta | Georgia | 30060 | United States | Details | |
| Piedmont Newnan Hospital | Newnan | Georgia | 30265 | United States | Details | |
| Summit Cancer Care PC | Savannah | Georgia | 31405 | United States | Details | |
| Piedmont Henry Hospital | Stockbridge | Georgia | 30281 | United States | Details | |
| St Luke?s Cancer Institute | Boise | Idaho | 83712 | United States | Details | |
| Northwestern University; Robert H. Lurie Comp Can Ctr | Chicago | Illinois | 60611 | United States | Details | |
| OSF Little Company of Mary Hospital | Evergreen Park | Illinois | 60805 | United States | Details | |
| Springfield Clinic; Department of Hematology and Oncology | Springfield | Illinois | 62702 | United States | Details | |
| Duly Health and Care | Tinley Park | Illinois | 60487 | United States | Details | |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | United States | Details | |
| Mission Cancer + Blood - IMMC | Des Moines | Iowa | 50309 | United States | Details | |
| University of Kansas Cancer Center | Westwood | Kansas | 66205 | United States | Details | |
| Pikeville Medical Center | Pikeville | Kentucky | 41501 | United States | Details | |
| LSU Health Baton Rouge; North Clinic | Baton Rouge | Louisiana | 70805 | United States | Details | |
| Our Lady of the Lake Physicians Group; Hematology/Oncology | Baton Rouge | Louisiana | 70808 | United States | Details | |
| Woman's Hospital | Baton Rouge | Louisiana | 70817 | United States | Details | |
| Pontchartrain Cancer Center | Covington | Louisiana | 70433 | United States | Details | |
| Northern Light Cancer Center/Oncology Research | Brewer | Maine | 04412 | United States | Details | |
| New England Cancer Specialists | Scarborough | Maine | 04074 | United States | Details | |
| Anne Arundel Health System Research Institute | Annapolis | Maryland | 21401 | United States | Details | |
| University of Maryland Greenebaum Cancer Center | Baltimore | Maryland | 21201 | United States | Details | |
| Mercy Medical Center | Baltimore | Maryland | 21202 | United States | Details | |
| TidalHealth Peninsula Regional; Richard A. Henson Research | Ocean Pines | Maryland | 21811 | United States | Details | |
| TidalHealth Peninsula Regional | Salisbury | Maryland | 21801 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Dana Farber/Harvard Cancer Center (Foxborough) | Foxboro | Massachusetts | 02035 | United States | Details | |
| Dana Farber/Harvard Cancer Center (Milford) | Milford | Massachusetts | 01757 | United States | Details | |
| Dana Farber/Harvard Cancer Center (Weymouth) | Weymouth | Massachusetts | 02190 | United States | Details | |
| Michigan Center of Medical Research | Farmington Hills | Michigan | 48334 | United States | Details | |
| Metro-Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | United States | Details | |
| Oncology Hematology West PC | Grand Island | Nebraska | 68803 | United States | Details | |
| Nebraska Cancer Specialists; Oncology Hematology West, PC | Omaha | Nebraska | 68130 | United States | Details | |
| Renown Regional Medical Center | Reno | Nevada | 89502 | United States | Details | |
| Memorial Sloan Kettering - Basking Ridge; Pharmacy | Basking Ridge | New Jersey | 07920 | United States | Details | |
| Summit Medical Group; MD Anderson Cancer Center | Florham Park | New Jersey | 07932 | United States | Details | |
| Memorial Sloan Kettering - Monmouth | Middletown | New Jersey | 07748 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center; Hematology/Oncology | Montvale | New Jersey | 07645 | United States | Details | |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | United States | Details | |
| Memorial Sloan Kettering | Commack | New York | 11725 | United States | Details | |
| Memorial Sloan Kettering Cancer Center at Westchester | Harrison | New York | 10604 | United States | Details | |
| Memorial Sloan Kettering Cancer Center; Drug Shipment | Long Island City | New York | 11104 | United States | Details | |
| The Blavatnik Family ? Chelsea Medical Center at Mount Sinai | New York | New York | 10011 | United States | Details | |
| Icahn School of Medicine at Mount Sinai; Department of Pharmacy | New York | New York | 10029 | United States | Details | |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center; Hematology/Oncology | New York | New York | 10065 | United States | Details | |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | United States | Details | |
| Memorial Sloan Kettering Cancer Center at Nassau | Uniondale | New York | 11553 | United States | Details | |
| SCRI Mark H. Zangmeister Center | Columbus | Ohio | 43219 | United States | Details | |
| University of Oklahoma Health Sciences Center; Peggy and Charles Stephenson Oklahoma Cancer Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Oklahoma Cancer Specialists and Research Institute | Tulsa | Oklahoma | 74146 | United States | Details | |
| St Charles Medical Center Bend; ATTN: Research | Bend | Oregon | 97701 | United States | Details | |
| Oncology Research Office | Harrisburg | Pennsylvania | 17109 | United States | Details | |
| Abramson Cancer Center; Univ of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| UPMC Hillman Cancer Center - Magee-Women?s Hospital | Pittsburgh | Pennsylvania | 15213 | United States | Details | |
| Abramson Cancer Center Chester County Hospital; Hematology, Medical Oncology | West Chester | Pennsylvania | 19380 | United States | Details | |
| McGlinn Cancer Institute at Reading Hospital | West Reading | Pennsylvania | 19611 | United States | Details | |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | United States | Details | |
| West Cancer Center | Germantown | Tennessee | 38138 | United States | Details | |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916-2305 | United States | Details | |
| Texas Oncology P.A - Beaumont | Beaumont | Texas | 77702 | United States | Details | |
| Texas Oncology | Bedford | Texas | 76022 | United States | Details | |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | United States | Details | |
| Texas Oncology-Denton South | Denton | Texas | 76201 | United States | Details | |
| Texas Oncology, P.A. - El Paso; El Paso Cancer Treatment Center, West | El Paso | Texas | 79915 | United States | Details | |
| Methodist Hospital Research Institute | Houston | Texas | 77030 | United States | Details | |
| Millennium Research & Clinical Development | Houston | Texas | 77090 | United States | Details | |
| Texas Oncology Central - South | McAllen | Texas | 78503 | United States | Details | |
| USOR - Texas Oncology - San Antonio Northeast | San Antonio | Texas | 78217 | United States | Details | |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | United States | Details | |
| Inova Fairfax Hospital | Falls Church | Virginia | 22031 | United States | Details | |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | United States | Details | |
| Multicare Institute for Research and Innovation | Tacoma | Washington | 98405 | United States | Details | |
| Northwest Medical Specialties, PLLC; Research Department | Tacoma | Washington | 98405 | United States | Details | |
| UW Cancer Center at ProHealth | Waukesha | Wisconsin | 53188 | United States | Details | |
| Instituto Angel Roffo | Ciudad Autonoma Buenos Aires | C1417DTB | Argentina | Details | ||
| Consultorios Médicos Dr. Doreski | Ciudad Autonoma Buenos Aires | C1426ABP | Argentina | Details | ||
| Centro de Neurociencias Invest y Tratamiento | Ciudad Autonoma de Buenos Aires | C1125ABD | Argentina | Details | ||
| Sanatorio Allende | Cordoba | X5000JHQ | Argentina | Details | ||
| Centro Medico Privado CEMAIC | Cordoba | X5008HHW | Argentina | Details | ||
| Hospital Privado de La Comunidad | Mar Del Plata | B7603CBM | Argentina | Details | ||
| Fundacion Centro Oncologico de Integracion Regional (COIR) | Mendoza | M5500AYB | Argentina | Details | ||
| Centro de Investigacion Pergamino SA | Pergamino | B2700CPM | Argentina | Details | ||
| Instituto Medico de la Fundacion Estudios Clinicos | Rosario | S2000DEJ | Argentina | Details | ||
| Sanatorio Parque S.A. | Rosario | S2000QGB | Argentina | Details | ||
| Hospital Provincial del Centenario | Rosario | S2002KDS | Argentina | Details | ||
| Instituto de Oncologia de Rosario | Rosario | S2013KZE | Argentina | Details | ||
| Centro Polivalente de Asistencia e Investigacion Clinica - CER San Juan | San Juan | J5402DIL | Argentina | Details | ||
| Organizacion Medica de Investigacion | San Nicolás | C1015ABO | Argentina | Details | ||
| Centro de Investigación Clínica ? Clínica Viedma | Viedma | R8500ACE | Argentina | Details | ||
| Marienhospital Bottrop | Bottrop | 46236 | Germany | Details | ||
| St. Johannes-Hospital | Dortmund | 44137 | Germany | Details | ||
| Universitaetsklinikum Duesseldorf | Dusseldorf | 40225 | Germany | Details | ||
| Frauenarztpraxis Dr. Apel, Dr. Kolpin | Erfurt | 99084 | Germany | Details | ||
| Universitaetsklinikum Erlangen | Erlangen | 91054 | Germany | Details | ||
| Franziskus-Hospital Harderberg | Georgsmarienhutte | 49124 | Germany | Details | ||
| Universitätsklinikum Heidelberg | Heidelberg | 69120 | Germany | Details | ||
| Universitaetsklinikum des Saarlandes | Homburg/Saar | 66421 | Germany | Details | ||
| Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz | Mainz | 55101 | Germany | Details | ||
| Universitatsklinikum Munster | Münster | 48149 | Germany | Details | ||
| University of Athens, Hematological Clinic,; First Department of Propaedeutic Medicine | Athens | 115 28 | Greece | Details | ||
| Attikon University General Hospital | Chaidari | 124 62 | Greece | Details | ||
| Metropolitan General Hospital | Cholargos | 155 62 | Greece | Details | ||
| University General Hospital of Heraklion | Heraklio | 711 10 | Greece | Details | ||
| University General Hospital of Larissa | Larissa | 412 21 | Greece | Details | ||
| IASO Obstetrics Gynecology Clinic | Marousi | 151 23 | Greece | Details | ||
| Agios Loucas Clinic SA | Panorama | 552 36 | Greece | Details | ||
| Olympion Clinic | Patras | 264 43 | Greece | Details | ||
| University General Hospital of Patras | Patras | 265 00 | Greece | Details | ||
| Metaxa Cancer Hospital of Piraeus | Peiraias | 185 37 | Greece | Details | ||
| Interbalkan Medical Center of Thessaloniki | Thessaloniki | 546 39 | Greece | Details | ||
| Euromedica PPDS | Thessaloniki | 546 45 | Greece | Details | ||
| Azienda Ospedaliero - Universitaria di Modena Policlinico | Modena | Emilia-Romagna | 41110 | Italy | Details | |
| Istituto Nazionale Tumori Regina Elena IRCCS | Roma | Lazio | 00144 | Italy | Details | |
| Ospedale Policlinico San Martino | Genova | Liguria | 16132 | Italy | Details | |
| Asst Grande Ospedale Metropolitano Niguarda | Milano | Lombardia | 20162 | Italy | Details | |
| Universita Degli Studi Di Milano-Bicocca - Azienda Ospedaliera San Gerardo Di Monza | Monza | Lombardia | 20900 | Italy | Details | |
| Azienda Ospedaliero Universitaria Ospedali Riuniti | Torrette Di Ancona | Marche | 60126 | Italy | Details | |
| Azienda Ospedaliero Universitaria di Ferrara - U.O. Di Oncologia | Cona (FE) | Veneto | 44124 | Italy | Details | |
| "Azienda Ospedaliera Universitaria Integrata Verona Ospedale Borgo Trento" | Verona | Veneto | 37124 | Italy | Details | |
| Aichi Cancer Center | Aichi | 464-8681 | Japan | Details | ||
| Nagoya University Hospital | Aichi | 466-8560 | Japan | Details | ||
| Chiba Cancer Center | Chiba | 260-8717 | Japan | Details | ||
| National Cancer Center Hospital East | Chiba | 277-8577 | Japan | Details | ||
| Shikoku Cancer Center | Ehime | 791-0280 | Japan | Details | ||
| Hiroshima City Hiroshima Citizens Hospital | Hiroshima | 730-8518 | Japan | Details | ||
| Hiroshima University Hospital | Hiroshima | 734-8551 | Japan | Details | ||
| Hokkaido University Hospital | Hokkaido | 060-8648 | Japan | Details | ||
| Hyogo Cancer Center | Hyogo | 673-0021 | Japan | Details | ||
| University of Tsukuba Hospital | Ibaraki | 305-8576 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
| Tokai University Hospital | Kanagawa | 259-1193 | Japan | Details | ||
| Kumamoto University Hospital | Kumamoto | 860-8556 | Japan | Details | ||
| Kyoto University Hospital | Kyoto | 606-8507 | Japan | Details | ||
| Fukushima Medical University Hospital | Miyagi | 960-1295 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Naha-nishi Clinic | Okinawa | 901-0154 | Japan | Details | ||
| National Hospital Organization Osaka National Hospital | Osaka | 540-0006 | Japan | Details | ||
| Osaka International Cancer Institute | Osaka | 541-8567 | Japan | Details | ||
| Juntendo University Hospital | Tokyo | 113-8431 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Tokyo | 135-8550 | Japan | Details | ||
| Chungbuk National University Hospital | Cheongju-si | 28644 | Korea, Republic of | Details | ||
| Soon Chun Hyang University Cheonan Hospital | Dongnam-gu, Cheonan-si | 31151 | Korea, Republic of | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| CHA Bundang Medical Center | Gyeonggi-do | 13496 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 463-707 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System - PPDS | Seoul | 03722 | Korea, Republic of | Details | ||
| Korea University Guro Hospital | Seoul | 08308 | Korea, Republic of | Details | ||
| National University Hospital | Singapore | 117599 | Singapore | Details | ||
| Oncocare Cancer Centre | Singapore | 258499 | Singapore | Details | ||
| Rainbow Oncology Private Practice | Amanzimtoti | 4126 | South Africa | Details | ||
| Wits Health Research | City Of Johannesburg | 2193 | South Africa | Details | ||
| Hopelands Cancer Centre | Hilton | 3245 | South Africa | Details | ||
| Medical Oncology Centre of Rosebank; Oncology | Johannesburg | 2196 | South Africa | Details | ||
| Wilgers Oncology Centre | Pretoria | 0001 | South Africa | Details | ||
| Hospital Dexeus; Oncología | Barcelona | 08028 | Spain | Details | ||
| Hospital Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
| C.H. Regional Reina Sofia - PPDS | Cordoba | 14004 | Spain | Details | ||
| Hospital Universitario Virgen de Las Nieves | Granada | 18014 | Spain | Details | ||
| Complejo Hospitalario Universitario A Coruña (CHUAC, Materno Infantil), Oncología | La Coruña | 15006 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon | Madrid | 28007 | Spain | Details | ||
| Hospital Universitario Ramón y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Clinico San Carlos | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Hospital General Universitario J.M Morales Meseguer; Servicio de Oncologia | Murcia | 30008 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Changhua Christian Hospital | Chang Hua | 500 | Taiwan | Details | ||
| Chang Gung Memorial Hospital | Kaohsiung Country | 833 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 70457 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology | Taipei City | 11259 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
| Chang Gung Memorial Hospital - Linkou Branch | Taipei | Taiwan | Details | |||
| Memorial Ankara Hastanesi | Ankara | 06520 | Turkey | Details | ||
| Dicle University Medical Faculty | Diyarbak?r | 21280 | Turkey | Details | ||
| SAKARYA University Medical Faculty | Sakarya | 811 | Turkey | Details | ||
| Dorset County Hospital | Dorchester | DT1 2JY | United Kingdom | Details | ||
| North Middlesex Uni Hospital; Haematology Dept | London | N18 1QX | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| Nottingham City Hospital | Nottingham | NG5 1PB | United Kingdom | Details |