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| NCT ID | NCT05338970 |
| Title | HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Daiichi Sankyo, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | NOR | NLD | ITA | GBR | FRA | ESP | DEU | CHE | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | United States | Details | |
| Highlands Oncology | Springdale | Arkansas | 72762 | United States | Details | |
| City of Hope | Duarte | California | 91010 | United States | Details | |
| Moores Cancer Center at the UC San Diego Health | La Jolla | California | 92037 | United States | Details | |
| Scripps MD Anderson Cancer Center | La Jolla | California | 92037 | United States | Details | |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| Kaiser Permanente - Vallejo Medical Center | Vallejo | California | 94589 | United States | Details | |
| Innovative Clinical Research Institute | Whittier | California | 90603 | United States | Details | |
| Sarah Cannon/Florida Cancer Specialists - FCS South | Port Charlotte | Florida | 33980 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| St Luke's Cancer Institute | Boise | Idaho | 83712 | United States | Details | |
| American Oncology Partners of Maryland | Bethesda | Maryland | 20817 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | United States | Details | |
| Hackensack Meridian Health-Southern Ocean Medical Center | Manahawkin | New Jersey | 08050 | United States | Details | |
| Montefiore Medical Center | Bronx | New York | 10467 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Providence Portland Medical Center | Portland | Oregon | 97213 | United States | Details | |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75235 | United States | Details | |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | United States | Details | |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | United States | Details | |
| University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53792 | United States | Details | |
| The Chris O'Brien Lifehouse | Camperdown | 2050 | Australia | Details | ||
| St George Public Hospital | Kogarah | 2217 | Australia | Details | ||
| Liverpool Hospital | Liverpool | 2170 | Australia | Details | ||
| Austin Hospital | Melbourne | 3084 | Australia | Details | ||
| St John of God Subiaco Hospital | Subiaco | 6008 | Australia | Details | ||
| Princess Alexandra Hospital | Woolloongabba | 4102 | Australia | Details | ||
| Landeskrankenhaus Feldkirch | Feldkirch | 6800 | Austria | Details | ||
| Medizinische Universitaet Innsbruck | Innsbruck | 6020 | Austria | Details | ||
| Klinikum Klagenfurt Pulmologie | Klagenfurt | 9020 | Austria | Details | ||
| Klinikum Wels-Grieskirchen | Wels | 4600 | Austria | Details | ||
| Karl Landsteiner Institut fur Lungenforschung und pneumologische Onkologie c/o Klinik Floridsdorf | Wien | 1210 | Austria | Details | ||
| Cliniques Universitaires Saint-Luc | Brussels | 1200 | Belgium | Details | ||
| UZ Leuven | Leuven | 3000 | Belgium | Details | ||
| AZ Sint Maarten Mechelen | Mechelen | 2800 | Belgium | Details | ||
| AZ Delta | Roeselare | 8800 | Belgium | Details | ||
| William Osler Health System - Brampton Civic Hospital | Brampton | L6R 3J7 | Canada | Details | ||
| Peking University Cancer Hospital | Beijing | 100142 | China | Details | ||
| Jilin Cancer Hospital | Chang chun | 130021 | China | Details | ||
| Hunan Cancer Hospital | Changsha | 410013 | China | Details | ||
| University of Electronic Science Technology of China UESTC - Sichuan Cancer Hospital Institute Sichuan Provincial Tumor Hospital | Chengdu | 610041 | China | Details | ||
| National Cancer Center Hospital East | Chibi | 260-0013 | China | Details | ||
| Fujian Medical University - Union Hospital Foochow Christian Union Hospital | Fuzhou | 350001 | China | Details | ||
| Guangdong Academy of Medical Science (GAMS) - Guangdong Provincial Peoples Hospital | Guangzhou | 510080 | China | Details | ||
| The First Affiliated Hospital Sun-Yat-Sen University | Guangzhou | 510080 | China | Details | ||
| Pecking University Third Hospital | Haidian | 100191 | China | Details | ||
| The First Affiliated Hospital of College of Medicine Zhejiang University | Hangzhou | 310003 | China | Details | ||
| Zhejiang Cancer hospital | Hangzhou | 310022 | China | Details | ||
| Harbin Medical University - Tumor Hospital The Third Affiliated Hospital | Harbin | 150081 | China | Details | ||
| The First Affiliated Hospital - Anhui Medical University Dept of Medical Oncology | Hefei | 230022 | China | Details | ||
| Henan Provincial Peoples Hospital | Henan | 450003 | China | Details | ||
| The Second Affiliated Hospital of Kunming Medical University | Kunming | 650033 | China | Details | ||
| Lin Yi Cancer Hospital | Linyi | 276000 | China | Details | ||
| General Hospital of Eastern Theater Command | Nanjing | 210002 | China | Details | ||
| The First Affiliated Hospital of Guangxi Medical University | Nanning | 530021 | China | Details | ||
| Fudan University - Shanghai Cancer Center FUSCC | Shanghai | 200032 | China | Details | ||
| Cancer Hospital of Shantou University Medical College | Shantou | 515041 | China | Details | ||
| The First Hospital of China Medical University | Shenyang | 110001 | China | Details | ||
| Union Hospital of Tongji Medical College Huazhong University of Science and Technology | Wuhan | 430022 | China | Details | ||
| Huazhong University of Science and Technology - Tongji Medical College - Tongji Hospital TJH | Wuhan | 430030 | China | Details | ||
| The First Affiliate Hospital of Xi'an Jiaotong University | Xi'an | 710061 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| Affiliated Cancer Hospital of Xinjiang Medical University | Ürümqi | 830000 | China | Details | ||
| Hopital Morvan CHU de Brest | Brest | 29609 | France | Details | ||
| Centre Francois Baclesse | Caen | 14076 CEDEX 05 | France | Details | ||
| Centre Francois Baclesse | Caen | 14076 | France | Details | ||
| Centre Leon Berard | Lyon | 69008 | France | Details | ||
| Montpellier Cancer Institute ICM | Montpellier | 34298 | France | Details | ||
| Institut Curie | Paris Cedex 05 | 75005 | France | Details | ||
| APHP - Hopital Saint Louis | Paris | 75010 | France | Details | ||
| Centre Hospitalier Lyon Sud | Pierre-Bénite | 69495 | France | Details | ||
| Centre Hospitalier Universitaire (CHU) de Rennes - Hopital de Pontchaillou | Rennes | 35000 | France | Details | ||
| Institut de Cancrologie de lOuest ICO | Saint-Herblain | 44805 | France | Details | ||
| Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Universitaetsklinikum Essen | Essen | 45147 | Germany | Details | ||
| Klinikum Esslingen GmbH | Esslingen | 73730 | Germany | Details | ||
| IKF Krankenhaus Nordwest | Frankfurt am main | 60488 | Germany | Details | ||
| Asklepios Fachklinik Muenchen-Gauting | Gauting | 82131 | Germany | Details | ||
| Universitatsklinik Giessen und Marburg | Gießen | 35392 | Germany | Details | ||
| LungenClinic Grosshansdorf | Großhansdorf | 22927 | Germany | Details | ||
| Thoraxklinik Heidelberg gGmbH | Heidelberg | 69126 | Germany | Details | ||
| LKI Lungenfachklinik Immenhausen | Immenhausen | 34376 | Germany | Details | ||
| Klinikverbund Allgaeu | Kempten | 87439 | Germany | Details | ||
| Pius-Hospital Oldenburg | Oldenburg | 26121 | Germany | Details | ||
| Pamela Youde Nethersole Eastern Hospital | Hong Kong | 00852 | Hong Kong | Details | ||
| Prince of Wales Hospital | Hong Kong | 999077 | Hong Kong | Details | ||
| University of Hong Kong/Queen Mary Hospital | Hong Kong | 999077 | Hong Kong | Details | ||
| Queen Elizabeth Hospital | Hong Kong | Hong Kong | Details | |||
| IRCCS Istituto Oncologico Giovanni Paolo II | Bari | 70124 | Italy | Details | ||
| University G. D'Annunzio Chieti | Chieti | 66100 | Italy | Details | ||
| Ospedale San Luca | Lucca | 55100 | Italy | Details | ||
| IRCCS Istituto Europeo di Oncologia | Milano | 20141 | Italy | Details | ||
| Asst Grande Ospedale Metropolitano Niguarda | Milano | 20162 | Italy | Details | ||
| Azienda Ospedaliero-Universitaria San Luigi Gonzaga | Orbassano | 10043 | Italy | Details | ||
| Azienda Ospedaliero Universitaria di Parma | Parma | 43126 | Italy | Details | ||
| Ospedale Santa Maria della Misericordia | Perugia | 06132 | Italy | Details | ||
| IFO Regina Elena | Roma | 00144 | Italy | Details | ||
| IRCCS Humanitas Research Hospital | Rozzano | 20089 | Italy | Details | ||
| ASST Sette Laghi | Varese | 21100 | Italy | Details | ||
| Hyogo Cancer Center | Akashi | 673-8558 | Japan | Details | ||
| Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
| Saitama Medical University International Medical Center | Hidaka | 350-1298 | Japan | Details | ||
| Kansai Medical University Hospital | Hirakata | 573-1191 | Japan | Details | ||
| Iwakuni Clinical Center | Iwakuni | 740-8510 | Japan | Details | ||
| Izumi City General Hospital | Izumi | 594-0073 | Japan | Details | ||
| Kanazawa University Hospital | Kanazawa | 920-8641 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Koto-Ku | 135-8550 | Japan | Details | ||
| Saiseikai Kumamoto Hospital | Kumamoto | 861- 4193 | Japan | Details | ||
| Kurashiki Central Hospital | Kurashiki | 710-8602 | Japan | Details | ||
| Kurume University Hospital | Kurume | 830-0011 | Japan | Details | ||
| Matsusaka Municipal Hospital | Matsusaka | 515-8544 | Japan | Details | ||
| NHO Shikoku Cancer Center | Matsuyama | 791-0280 | Japan | Details | ||
| National Hospital Organization Nagoya Medical Center | Nagoya | 460-0001 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| National Hospital Organization Hokkaido Cancer Center | Sapporo | 003-0804 | Japan | Details | ||
| Sendai Kousei Hospital | Sendai | 980-0873 | Japan | Details | ||
| Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital | Tokyo | 113-8677 | Japan | Details | ||
| Fujita Health University Hospital | Toyoake | 470-1192 | Japan | Details | ||
| Wakayama Medical University Hospital | Wakayama | 641-8509 | Japan | Details | ||
| Kindai University Hospital | Ōsaka-sayama | 589-8511 | Japan | Details | ||
| Chungbuk National University Hospital | Cheongju-si | 28644 | Korea, Republic of | Details | ||
| National Cancer Center | Goyang | 10323 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam | 463-707 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea, Seoul St. Marys Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 135-710 | Korea, Republic of | Details | ||
| Netherlands Cancer Institute | Amsterdam | 1066 CX | Netherlands | Details | ||
| Rijnstate Ziekenhuis | Arnhem | 6815 AD | Netherlands | Details | ||
| St. Jansdal Ziekenhuis | Harderwijk | 3844 DG | Netherlands | Details | ||
| Leiden University Medical Center | Leiden | 2333ZA | Netherlands | Details | ||
| Erasmus MC | Rotterdam | 3015 CD | Netherlands | Details | ||
| University Medical Center Utrecht | Utrecht | 3584 CX | Netherlands | Details | ||
| Akershus University Hospital | Nordbyhagen | 1478 | Norway | Details | ||
| Oslo University Hospital-The Norwegian Radium Hospital | Oslo | 0379 | Norway | Details | ||
| Stavanger University Hospital | Stavanger | 8100 | Norway | Details | ||
| II Klinika Chorob Pluc i Gruzlicy | Białystok | 15-450 | Poland | Details | ||
| Onko-Centrum Sp. z o.o. | Lublin | 20-250 | Poland | Details | ||
| Med Polonia Sp. z o.o. | Poznań | 60-693 | Poland | Details | ||
| Centro Clinico Champalimaud | Lisboa | 1400-038 | Portugal | Details | ||
| Instituto Portugues de Oncologio de Lisboa | Lisbon | 1908-072 | Portugal | Details | ||
| Centro Hospitalar Universitario do Porto - Hospital de Santo Antonio | Porto | 4099-001 | Portugal | Details | ||
| Centro Hospitalar de Vila Nova de Gaia - Espinho | Porto | 4434-502 | Portugal | Details | ||
| National University Cancer Institute National University Hospital | Singapore | 119074 | Singapore | Details | ||
| National Cancer Centre Singapore NCCS | Singapore | 169610 | Singapore | Details | ||
| Tan Tock Seng Hospital | Singapore | 308433 | Singapore | Details | ||
| ICON Cancer Centre | Singapore | 329563 | Singapore | Details | ||
| Hospital Teresa Herrera C.H.U.A.C. | A Coruña | 15006 | Spain | Details | ||
| Hospital del Mar | Barcelona | 08003 | Spain | Details | ||
| Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic i Provincial de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Complejo Hospitalario Materno-Insular - Hospital Insular de Gran Canaria | Las Palmas De Gran Canaria | 35016 | Spain | Details | ||
| Hospital General Universitario Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| MD Anderson Cancer Center | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Fundacion Jimenez Diaz | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Hospital Regional Universitario Malaga | Málaga | 29010 | Spain | Details | ||
| Hospital Univeritario Marques de Valdecilla | Santander | 39120 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | 41071 | Spain | Details | ||
| Kantonsspital Graubuenden - Hauptstandort | Chur | 7000 | Switzerland | Details | ||
| Kantonsspital Winterthur KSW | Winterthur | 8400 | Switzerland | Details | ||
| E-Da Hospital | Kaohsiung City | 824 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| National Cheng Kung University Hospital NCKUH | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital NTUH | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Chang Gung Memorial Hospital-Linkou Branch | Taoyuan | 333 | Taiwan | Details | ||
| University Hospital Birmingham NHS Trust | Birmingham | B9 5SS | United Kingdom | Details | ||
| Beatson West of Scotland Cancer Centre | Glasgow | G12 0YN | United Kingdom | Details | ||
| Leeds Cancer Centre | Leeds | LS9 7TF | United Kingdom | Details | ||
| University Hospitals of Leicester | Leicester | LE15WW | United Kingdom | Details | ||
| Barts and The London NHS Trust - St Bartholomew s hospital - PET CT Centre | London | EC1A 7BE | United Kingdom | Details | ||
| The Royal Marsden Hospital NHS Foundation Trust | London | SW3 6JJ | United Kingdom | Details | ||
| The Royal Marsden NHS Foundation Trust | London | SW3 6JJ | United Kingdom | Details | ||
| The Christie Hospital | Manchester | M20 4BX | United Kingdom | Details | ||
| The Royal Wolverhampton NHS Trust | Wolverhampton | WV10 0QP | United Kingdom | Details |