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| NCT ID | NCT05456191 |
| Title | A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (>=18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (ASC4START) |
| Acronym | ASC4START |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SVK | ROU | NLD | ITA | HUN | GRC | GBR | FRA | DEU | CZE | CHE | CAN | BGR | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Rocky Mountain Cancer Centers | Boulder | Colorado | 80304 | United States | Details | |
| Illinois Cancer Care | Peoria | Illinois | 61615 | United States | Details | |
| Regions Hospital | Saint Paul | Minnesota | 55101 | United States | Details | |
| Messino Cancer Centers | Asheville | North Carolina | 28806 | United States | Details | |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45242 | United States | Details | |
| Williamette Cancer Center | Eugene | Oregon | 97401 | United States | Details | |
| Texas Oncology P A | Bedford | Texas | 76022 | United States | Details | |
| Texas Oncology PA Bedford | Bedford | Texas | 76022 | United States | Details | |
| Lumi Research | Kingwood | Texas | 77339 | United States | Details | |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | United States | Details | |
| Novartis Investigative Site | Caba | Buenos Aires | C1181ACH | Argentina | Details | |
| Novartis Investigative Site | Caba | Buenos Aires | C1221ADH | Argentina | Details | |
| Novartis Investigative Site | Buenos aires | C1039AAC | Argentina | Details | ||
| Novartis Investigative Site | Buenos Aires | C1114AAN | Argentina | Details | ||
| Novartis Investigative Site | Buenos Aires | C1425AUM | Argentina | Details | ||
| Novartis Investigative Site | Pleven | 5800 | Bulgaria | Details | ||
| Novartis Investigative Site | Plovdiv | 4002 | Bulgaria | Details | ||
| Novartis Investigative Site | Sofia | 1413 | Bulgaria | Details | ||
| Novartis Investigative Site | Sofia | 1797 | Bulgaria | Details | ||
| Novartis Investigative Site | Varna | 9010 | Bulgaria | Details | ||
| Novartis Investigative Site | London | Ontario | N6A 5W9 | Canada | Details | |
| Novartis Investigative Site | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Novartis Investigative Site | Praha 2 | Czech Republic | 128 20 | Czechia | Details | |
| Novartis Investigative Site | Brno Bohunice | 625 00 | Czechia | Details | ||
| Novartis Investigative Site | Plzen-Bory | 30599 | Czechia | Details | ||
| Novartis Investigative Site | Praha 10 | 100 34 | Czechia | Details | ||
| Novartis Investigative Site | Bordeaux | 33076 | France | Details | ||
| Novartis Investigative Site | Caen | 14033 | France | Details | ||
| Novartis Investigative Site | Clermont Ferrand | 63003 | France | Details | ||
| Novartis Investigative Site | Lille | 59037 | France | Details | ||
| Novartis Investigative Site | Lyon | 69373 | France | Details | ||
| Novartis Investigative Site | Marseille | 13273 | France | Details | ||
| Novartis Investigative Site | Nantes Cedex 1 | 44093 | France | Details | ||
| Novartis Investigative Site | Nice | 06202 | France | Details | ||
| Novartis Investigative Site | Paris 10 | 75475 | France | Details | ||
| Novartis Investigative Site | Poitiers | 86021 | France | Details | ||
| Novartis Investigative Site | Strasbourg | 67200 | France | Details | ||
| Novartis Investigative Site | Toulouse | 31059 | France | Details | ||
| Novartis Investigative Site | Vandoeuvre Les Nancy | 54511 | France | Details | ||
| Novartis Investigative Site | Mannheim | Baden Wuerttemberg | 68305 | Germany | Details | |
| Novartis Investigative Site | Muenchen | Bayern | 81241 | Germany | Details | |
| Novartis Investigative Site | Velbert | North Rhine-Westphalia | 42551 | Germany | Details | |
| Novartis Investigative Site | Dresden | Sachsen | 01307 | Germany | Details | |
| Novartis Investigative Site | Aachen | 52074 | Germany | Details | ||
| Novartis Investigative Site | Augsburg | 86179 | Germany | Details | ||
| Novartis Investigative Site | Bad Saarow | 15526 | Germany | Details | ||
| Novartis Investigative Site | Bayreuth | 95445 | Germany | Details | ||
| Novartis Investigative Site | Berlin | 13353 | Germany | Details | ||
| Novartis Investigative Site | Bonn | 53105 | Germany | Details | ||
| Novartis Investigative Site | Bremen | 28177 | Germany | Details | ||
| Novartis Investigative Site | Chemnitz | 09113 | Germany | Details | ||
| Novartis Investigative Site | Erlangen | 91054 | Germany | Details | ||
| Novartis Investigative Site | Essen | 45147 | Germany | Details | ||
| Novartis Investigative Site | Frankfurt | 60590 | Germany | Details | ||
| Novartis Investigative Site | Freiburg | 79106 | Germany | Details | ||
| Novartis Investigative Site | Halle S | 06120 | Germany | Details | ||
| Novartis Investigative Site | Hamburg | 20246 | Germany | Details | ||
| Novartis Investigative Site | Hannover | 30161 | Germany | Details | ||
| Novartis Investigative Site | Heidelberg | 69120 | Germany | Details | ||
| Novartis Investigative Site | Jena | 07740 | Germany | Details | ||
| Novartis Investigative Site | Leipzig | 04103 | Germany | Details | ||
| Novartis Investigative Site | Luebeck | 23538 | Germany | Details | ||
| Novartis Investigative Site | Magdeburg | 39104 | Germany | Details | ||
| Novartis Investigative Site | Marburg | 35039 | Germany | Details | ||
| Novartis Investigative Site | Muenchen | 80377 | Germany | Details | ||
| Novartis Investigative Site | Paderborn | 33098 | Germany | Details | ||
| Novartis Investigative Site | Regensburg | 93049 | Germany | Details | ||
| Novartis Investigative Site | Tuebingen | 72076 | Germany | Details | ||
| Novartis Investigative Site | Ulm | 89081 | Germany | Details | ||
| Novartis Investigative Site | Wuerzburg | 97080 | Germany | Details | ||
| Novartis Investigative Site | Ioannina | GR | 455 00 | Greece | Details | |
| Novartis Investigative Site | Thessaloniki | GR | 570 10 | Greece | Details | |
| Novartis Investigative Site | Athens | 106 76 | Greece | Details | ||
| Novartis Investigative Site | Athens | 115 27 | Greece | Details | ||
| Novartis Investigative Site | Patras | 265 00 | Greece | Details | ||
| Novartis Investigative Site | Budapest | H-1083 | Hungary | Details | ||
| Novartis Investigative Site | Budapest | H-1097 | Hungary | Details | ||
| Novartis Investigative Site | Eger | 3300 | Hungary | Details | ||
| Novartis Investigative Site | Ahmedabad | Gujrat | 380009 | India | Details | |
| Novartis Investigative Site | Chennai | Tamilnadu | 600036 | India | Details | |
| Novartis Investigative Site | Varanasi | Uttar Pradesh | 221010 | India | Details | |
| Novartis Investigative Site | Rishikesh | Uttarakhand | 249203 | India | Details | |
| Novartis Investigative Site | New Delhi | 110029 | India | Details | ||
| Novartis Investigative Site | Meldola | FC | 47014 | Italy | Details | |
| Novartis Investigative Site | Milano | MI | 20162 | Italy | Details | |
| Novartis Investigative Site | Pisa | PI | 56124 | Italy | Details | |
| Novartis Investigative Site | Roma | RM | 00144 | Italy | Details | |
| Novartis Investigative Site | Torino | TO | 10126 | Italy | Details | |
| Novartis Investigative Site | Amman | 11941 | Jordan | Details | ||
| Novartis Investigative Site | Bundang Gu | Gyeonggi Do | 13620 | Korea, Republic of | Details | |
| Novartis Investigative Site | Uijeongbu si | Gyeonggi Do | 11759 | Korea, Republic of | Details | |
| Novartis Investigative Site | Alor Setar | Kedah | 05460 | Malaysia | Details | |
| Novartis Investigative Site | Kuching | Sarawak | 93586 | Malaysia | Details | |
| Novartis Investigative Site | Petaling Jaya | Selangor Darul Ehsan | 46150 | Malaysia | Details | |
| Novartis Investigative Site | Kuala Lumpur | 59100 | Malaysia | Details | ||
| Novartis Investigative Site | Breda | 4818 CK | Netherlands | Details | ||
| Novartis Investigative Site | Muscat | 123 | Oman | Details | ||
| Novartis Investigative Site | Bucharest | District 2 | 022328 | Romania | Details | |
| Novartis Investigative Site | Targu Mures | Mures | 540136 | Romania | Details | |
| Novartis Investigative Site | Bucharest | 030 171 | Romania | Details | ||
| Novartis Investigative Site | Bucuresti | 021494 | Romania | Details | ||
| Novartis Investigative Site | Cluj-Napoca | 400124 | Romania | Details | ||
| Novartis Investigative Site | Craiova | 200136 | Romania | Details | ||
| Novartis Investigative Site | Sibiu | 550245 | Romania | Details | ||
| Novartis Investigative Site | Timisoara | 300079 | Romania | Details | ||
| Novartis Investigative Site | Singapore | 119074 | Singapore | Details | ||
| Novartis Investigative Site | Singapore | 169608 | Singapore | Details | ||
| Novartis Investigative Site | Singapore | S308433 | Singapore | Details | ||
| Novartis Investigative Site | Bratislava | 85107 | Slovakia | Details | ||
| Novartis Investigative Site | Soweto | Gauteng | 2013 | South Africa | Details | |
| Novartis Investigative Site | Pretoria | 0044 | South Africa | Details | ||
| Novartis Investigative Site | Geneve 14 | 1211 | Switzerland | Details | ||
| Novartis Investigative Site | Istanbul | TUR | 34098 | Turkey | Details | |
| Novartis Investigative Site | Ankara | 06230 | Turkey | Details | ||
| Novartis Investigative Site | Izmir | 35100 | Turkey | Details | ||
| Novartis Investigative Site | Abu Dhabi | United Arab Emirates | Details | |||
| Novartis Investigative Site | Glasgow | G12 0YN | United Kingdom | Details | ||
| Novartis Investigative Site | Gloucester | GL1 3NN | United Kingdom | Details | ||
| Novartis Investigative Site | London | SE5 9RS | United Kingdom | Details | ||
| Novartis Investigative Site | London | W12 0HS | United Kingdom | Details | ||
| Novartis Investigative Site | Newport | NP20 2UB | United Kingdom | Details |