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| NCT ID | NCT05462717 |
| Title | Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | No |
| Sponsors | Revolution Medicines, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | POL | ITA | FRA | ESP | CZE | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Highlands Oncology Group | Springdale | Arkansas | 72762 | United States | Details | |
| UC Irvine Cancer Center | Orange | California | 92868 | United States | Details | |
| UC Davis Cancer Center | Sacramento | California | 95817 | United States | Details | |
| UCSF | San Francisco | California | 94158 | United States | Details | |
| University of Miami School of Medicine Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| American Oncology Partners of Maryland | Bethesda | Maryland | 20817 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14203 | United States | Details | |
| MSK Cancer Center | New York | New York | 10021 | United States | Details | |
| Columbia University Irving Medical Center | New York | New York | 10032 | United States | Details | |
| Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| Next Oncology | San Antonio | Texas | 78229 | United States | Details | |
| START | San Antonio | Texas | 78229 | United States | Details | |
| Next Oncology Virginia | Fairfax | Virginia | 22031 | United States | Details | |
| Southside Cancer Care Centre | Sydney | New South Wales | 2228 | Australia | Details | |
| Peninsula & South Eastern Haematology and Oncology Group | Frankston | Victoria | 3199 | Australia | Details | |
| Austin Health, Olivia Newton-John Cancer Research & Wellness Centre | Heidelberg | Victoria | 3084 | Australia | Details | |
| South West Health Care | Warrnambool | Victoria | 3280 | Australia | Details | |
| NH Hospital a.s. | Hořovice | 268 31 | Czechia | Details | ||
| Klinika onkologie a radioterapie, Fakultni Nemocnice Hradec Kralove | Hradec Králové | 50005 | Czechia | Details | ||
| Onkologicka klinika, Fakultni Nemocnice Olomouc | Olomouc | 77900 | Czechia | Details | ||
| ICO | Angers | 49055 | France | Details | ||
| CHU Bordeaux Hospital Saint-Andre | Bordeaux | 33000 | France | Details | ||
| Centre Jean Perrin | Clermont-Ferrand | 63011 | France | Details | ||
| Centre Oscar Lambret | Lille | 59000 | France | Details | ||
| Centre Léon Bérard | Lyon | 69008 | France | Details | ||
| CHU Nantes | Nantes | 44093 | France | Details | ||
| ICANS | Strasbourg | 67200 | France | Details | ||
| Istituto Europeo Oncologico | Milano | 20141 | Italy | Details | ||
| S.C. Oncologia Falck, Dipartimento Ematologia ed Oncologia Niguarda Cancer Center | Milan | 20162 | Italy | Details | ||
| Istituto Nazionale Tumori Fondazione G. Pascale | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliero-Universitaria San Luigi Gonzaga | Orbassano | 10043 | Italy | Details | ||
| Fondazione IRCCS Policlinico San Matteo | Pavia | 27100 | Italy | Details | ||
| Centro Ricerche Cliniche di Verona s.r.l. | Verona | 37134 | Italy | Details | ||
| Ajou University Hospital | Suwon-si | Gyeonggi-do | 16499 | Korea, Republic of | Details | |
| Korea University Hospital | Seoul | 02708 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 3080 | Korea, Republic of | Details | ||
| Severance Hospital | Seoul | 3722 | Korea, Republic of | Details | ||
| University Malaya Medical Centre | Kuala Lumpur | 59100 | Malaysia | Details | ||
| Sarawak General Hospital | Kuching | 93586 | Malaysia | Details | ||
| Med - Polonia Sp. z o. o. | Poznań | 60-693 | Poland | Details | ||
| Narodowy Instytut Onkologii | Warsaw | 02-781 | Poland | Details | ||
| Instytut MSF Sp zoo | Łódź | 90-302 | Poland | Details | ||
| MSB General Hospital | Belgrade | 11000 | Serbia | Details | ||
| Clinical hospital center Bezanijska Kosa | Belgrade | 11071 | Serbia | Details | ||
| Institute for pulmonary diseases Sremska Kamenica | Sremska Kamenica | 21204 | Serbia | Details | ||
| National Cancer centre Singapore | Singapore | 168583 | Singapore | Details | ||
| NEXT Oncology IOB Hospital Quirónsalud | Barcelona | 08023 | Spain | Details | ||
| ICO Hospitalet | Barcelona | 08908 | Spain | Details | ||
| Clínica Universidad de Navarra | Madrid | 28027 | Spain | Details | ||
| MD Anderson Cancer Center | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Fundación Jiménez Díaz | Madrid | 28040 | Spain | Details | ||
| Clinica Universidad de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hospital Universitario Quirónsalud | Pozuelo De Alarcón | 28223 | Spain | Details | ||
| Hospital Universitario Virgen del Rocío | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitario Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| E-DA hospital | Kaohsiung | Yanchao District | 82445 | Taiwan | Details | |
| Taipei Tzu Chi Hospital | New Taipei City | 231 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 70457 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10048 | Taiwan | Details | ||
| Siriraj Hospital | Bangkok Noi | 10700 | Thailand | Details | ||
| Chiang Mai University | Chiang Mai | 50200 | Thailand | Details | ||
| Khon Kaen University | Khon Kaen | 40002 | Thailand | Details |