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| NCT ID | NCT05502237 |
| Title | Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer (STAR-121) |
| Acronym | STAR-121 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Gilead Sciences |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| California Cancer Associates for Research and Excellence | San Marcos | California | 92069 | United States | Details | |
| Innovative Clinical Research Institute | Whittier | California | 90606 | United States | Details | |
| Eastern CT Hematology and Oncology Associates | Norwich | Connecticut | 06360 | United States | Details | |
| Lake City Cancer Care | Lake City | Florida | 32024 | United States | Details | |
| Florida Cancer Specialists | Sarasota | Florida | 34232 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Peachtree Hematology Oncology Consultants | Atlanta | Georgia | 30318 | United States | Details | |
| Illinois Cancer Care | Peoria | Illinois | 61615 | United States | Details | |
| Messino Cancer Centers | Asheville | North Carolina | 28806 | United States | Details | |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45242 | United States | Details | |
| Hematology & Oncology Associates | Eugene | Oregon | 97401 | United States | Details | |
| AHN Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | United States | Details | |
| Texas Oncology - Austin | Austin | Texas | 78745 | United States | Details | |
| Texas Oncology | Dallas | Texas | 75246 | United States | Details | |
| Texas Oncology- Denison | Sherman | Texas | 75090 | United States | Details | |
| US Oncology Investigational Products Center (IPC) | Arlington | Virginia | 22205 | United States | Details | |
| Oncology and Hematology Associates of Southwest Virginia, Inc | Blacksburg | Virginia | 24060 | United States | Details | |
| Northwest Cancer Specialists, PC | Vancouver | Washington | 98684 | United States | Details | |
| Investigaciones CORI S.R.L. | Capital | F5300COE | Argentina | Details | ||
| Centro Médico Privado Centro de Especialidades Médicas Ambulatorias e Investigación Clínica | Cardoba | X5008HHW | Argentina | Details | ||
| Centro Medico Barrio Parque | Ciudad Autanoma Buenos Aires | 1426 | Argentina | Details | ||
| Sanatorio Allende | Cordoba | 5000 | Argentina | Details | ||
| Sanatorio Britanico de Rosario | Rosario | 2000 | Argentina | Details | ||
| Sanatorio Parque de Rosario | Rosario | S2000DSV | Argentina | Details | ||
| Hospital Provincial del Centenario | Rosario | S2002KDS | Argentina | Details | ||
| Instituto Medico de la Fundacion Estudios Clinicos | Rosario | S2013DTC | Argentina | Details | ||
| CAIPO - Centro para la Atención Integral del Paciente Oncológico | San Miguel de Tucumán | 4000 | Argentina | Details | ||
| Clínica Viedma | Viedma | 8500 | Argentina | Details | ||
| Klinikum Klagenfurt am Woerthersee | Klagenfurt Am Woerthersee | Austria | Details | |||
| Ordensklinikum Linz GmbH, Elisabethinen | Linz | 4020 | Austria | Details | ||
| Klinikum Wels-Grieskirchen | Wels | 4600 | Austria | Details | ||
| Krankenhaus Nord - Klinik Floridsdorf | Wien | A-1140 | Austria | Details | ||
| Algemeen Ziekenhuis Sint-Lucas | Aalst | 9300 | Belgium | Details | ||
| Grand Hopital de Charleroi asbl (GHdC) | Charleroi | 6000 | Belgium | Details | ||
| AZ Sint-Maarten | Mechelen | 2800 | Belgium | Details | ||
| CHU UCL Namur / Site Sainte Elisabeth | Namur | 5000 | Belgium | Details | ||
| Cenantron Centro Avançado de Tratamento Oncologico Ltda | Belo Horizonte | 30130-090 | Brazil | Details | ||
| Hospital Evangelico de Cachoeiro de Itapemirim | Cachoeiro De Itapemirim | 29308-014 | Brazil | Details | ||
| Fundacao Universidade De Caxias Do Sul - FUCS/RS | Caxias Do Sul | 95070-560 | Brazil | Details | ||
| Instituto do Câncer do Ceará - ICC | Fortaleza | 60430-230 | Brazil | Details | ||
| Oncosite - Centro de Pesquisa Clinica em Oncologia LTDA | Ijui | 98700-000 | Brazil | Details | ||
| Centro Des Pesquisas Clinicas da Fundacao Doutor Amaral Carvalho | Jau | 17210080 | Brazil | Details | ||
| Irmandade da Santa Casa de Misericordia de Porto Alegre | Porto Alegre | 90020-090 | Brazil | Details | ||
| Hospital de Clínicas de Porto Alegre | Porto Alegre | 90035-903 | Brazil | Details | ||
| Hospital São Lucas da PUCRS | Porto Alegre | 90610-000 | Brazil | Details | ||
| Hospital Ana Nery Santa Cruz do Sul | Santa Cruz Do Sul | 96810-110 | Brazil | Details | ||
| Instituto Brasiliero de Controle do Cancer IBCC | Sao Paulo | 03102002 | Brazil | Details | ||
| Centre Integre de sante et de services sociaux de la Monteregie Centre | Greenfield Park | J4V 2H1 | Canada | Details | ||
| Moncton Hospital | Moncton | E1C 6Z8 | Canada | Details | ||
| CISSS des Laurentides | Quebec | J7Z 2V4 | Canada | Details | ||
| Centre de santé et services sociaux de Rimouski-Neigette | Rimouski | G5L5T1 | Canada | Details | ||
| Clinica Alemana de Santiago | Las Condes | 7550000 | Chile | Details | ||
| Orlandioncologia | Providencia | 7500006 | Chile | Details | ||
| Oncovida- Santiago | Providencia | 7510035 | Chile | Details | ||
| Clinica Puerto Montt | Puerto Montt | 5500243 | Chile | Details | ||
| Biocinetic | Santiago | 8331143 | Chile | Details | ||
| James Lind Centro de Investigacion del Cancer | Temuco | 4800827 | Chile | Details | ||
| Oncocentro APYS | Vina del Mar | 2520612 | Chile | Details | ||
| West China Hospital Sichuan University | Chengdu | 610041 | China | Details | ||
| Chongqing University Cancer Hospital | Chongqing | 400030 | China | Details | ||
| Deyang People's Hospital | Deyang | 618000 | China | Details | ||
| Fujian Cancer Hospital | Fuzhou | 350014 | China | Details | ||
| The First Affiliated Hospital of Guangzhou Medical University | Guangzhou | 510120 | China | Details | ||
| Guangzhou First People's Hospital | Guangzhou | 510180 | China | Details | ||
| Nanfang Hospital, Southern Medical University | Guangzhou | 510515 | China | Details | ||
| Zhejiang Cancer Hospital | Hangzhou | 310005 | China | Details | ||
| Anhui Chest Hospital | Hefei | 230022 | China | Details | ||
| The Second Affiliated Hospital of Nanchang University | Jiangxi | 330006 | China | Details | ||
| Shandong Cancer Hospital | Jinan | 250021 | China | Details | ||
| Jiangxi Chest Hospital | Nanchang | 330006 | China | Details | ||
| Nanjing Drum Tower Hospital | Nanjing | 210008 | China | Details | ||
| Guangxi Medical University Cancer Hospital | Nanning | 530021 | China | Details | ||
| Shanghai Chest Hospital | Shanghai | 200030 | China | Details | ||
| Shanghai Pulmonary Hospital | Shanghai | 200433 | China | Details | ||
| Cancer Hospital of Shantou University Medical College | Shantou | 0754-88555844 | China | Details | ||
| Tianjin Medical University Cancer Institute & Hospital | Tianjin | 300181 | China | Details | ||
| Union Hospital Tongji Medical College Huazhong University of Science and Technology | Wuhan | 430022 | China | Details | ||
| Tongji Hospital Tongji Medical College of Hust | Wuhan | 430030 | China | Details | ||
| The First Affiliated Hospital of Xian Jiaotong University | Xi'an | 710049 | China | Details | ||
| The First Affiliated Hospital of Xinxiang Medical College | Xinxiang | 453100 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| Ambroise-Pare Hospital, Assistance Publique - Hopitaux de Paris | Boulogne-Billancourt | 92100 | France | Details | ||
| CHU de Caen | Caen | 14000 | France | Details | ||
| Clinique Victor Hugo, Centre de Cancerologie de la Sarthe | Le Mans | 72000 | France | Details | ||
| Hopital Nord | Marseille | 13005 | France | Details | ||
| Institut de Cancer de Montpellier (ICM) - Val d'Aurelle | Montpellier | 34928 | France | Details | ||
| Centre Antoine Lacassagne | Nice | 6189 | France | Details | ||
| Institut de cancerologie de l'ouest (ICO) | Saint-Herblain | 44805 | France | Details | ||
| Hopital d'Instruction des Armees (HIA) Begin | Saint-Mandé | 94160 | France | Details | ||
| Centre Hospitalier de Saint-Quentin | Saint-Quentin | 2100 | France | Details | ||
| Institut de Cancerologie Strasbourg Europe (ICANS) | Strasbourg | 67033 | France | Details | ||
| Hôpital Foch | Suresnes | 92150 | France | Details | ||
| CHI de Toulon la Seyne-sur-Mer Hopital Sainte Musse | Toulon cedex | 83056 | France | Details | ||
| Augusta-Kranken-Anstalt gGmbh Klinik für Hämatologie Onkologie und Palliativmedizin | Bochum | 44791 | Germany | Details | ||
| Klinikum Chemnitz gGmbH | Chemnitz | 9116 | Germany | Details | ||
| Universitatsklinikum Essen / Westdeutsches Tumorzentrum, Innere Klinik (Tumorforschung) | Essen | 45122 | Germany | Details | ||
| Universitätsklinikum Freiburg, Klinik für Innere Medizin I Hämatologie, Onkologie und Stammzelltransplantation | Freiburg | 79106 | Germany | Details | ||
| LungenClinic Grosshansdorf | Grosshansdorf | 22927 | Germany | Details | ||
| Krankenhaus Martha-Maria Halle Dölau | Halle | 06120 | Germany | Details | ||
| Asklepios Kliniken Hamburg | Hamburg | 21075 | Germany | Details | ||
| Katholisches Marienkrankenhaus gGmbH | Hamburg | 22087 | Germany | Details | ||
| Lungenklinik Hemer, Zentrum fur Pneumologie and Thoraxchirurgie | Hemer | 58675 | Germany | Details | ||
| Vincentius-Diakonissen-Kliniken gAG, St. Vincentius-Kliniken, Medizinische Klinik 2 | Karlsruhe | 76137 | Germany | Details | ||
| Klinikum Kassel | Kassel | 34125 | Germany | Details | ||
| Kliniken der Stadt Köln ggmbh, Krankenhaus Koln-Merheim/Lungenklinik | Köln | 51109 | Germany | Details | ||
| Universitatsklinikum Schleswig-Holstein | Lubeck | 23538 | Germany | Details | ||
| Johannes Wesling Klinikum Minden | Minden | 32429 | Germany | Details | ||
| Munchen Klinik Bogenhausen, Klinik fur Pneumologie und Pneumologische Onkologie | Munchen | 81925 | Germany | Details | ||
| Sana Klinikum Offenbach GmbH, Medizinische Klinik IV, Hämatologie und Internistische Onkologie | Offenbach | 63069 | Germany | Details | ||
| Queen Elizabeth Hospital | Hong Kong | 999077 | Hong Kong | Details | ||
| Queen Mary Hospital | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hospital | New Territories | Hong Kong | Details | |||
| Soroka University Medical Center, Itzchak Rager Blvd. | Beer Seva | 84101 | Israel | Details | ||
| Shaare Zedek Medical Center | Jerusalem | 9103102 | Israel | Details | ||
| Oncology Institute, Galilee Medical Center, Route 89 Nahariya-Cabri | Nahariya | Israel | Details | |||
| Rabin Medical Center | Petah Tiqva | 49100 | Israel | Details | ||
| Kaplan Medical Center | Rehovot | 76100 | Israel | Details | ||
| Tel-Aviv Sourasky Medical Center | Tel Aviv | 64239 | Israel | Details | ||
| Azienda Ospedaliera San Giuseppe Moscati | Avellino | Italy | Details | |||
| IRCCS Fondazoine del Piemonte per l'Oncologia | Candiolo | 10060 | Italy | Details | ||
| Azienda Socio Sanitaria Territoriale di Cremona | Cremona | 26100 | Italy | Details | ||
| Ospedale Policlinico San Martino | Genova | 16132 | Italy | Details | ||
| Ospedale San Raffaele | Milano | 20132 | Italy | Details | ||
| Azienda Ospedaliero Universitaria di Modena | Modena | 41124 | Italy | Details | ||
| AORN Cardarelli | Naples | 80131 | Italy | Details | ||
| Azienda Ospedaliera dei Colli | Napoli | 80131 | Italy | Details | ||
| IRCCS Policlinico S. Matteo, Dipartimento Oncologia Ematologia-Oncologia Medica | Pavia | 27100 | Italy | Details | ||
| Azienda Sanitaria Territoriale Pesaro e Urbino (AST) | Pesaro | 61122 | Italy | Details | ||
| Ospedale Guglielmo da Saliceto AUSL di Piacenza | Piacenza | 29100 | Italy | Details | ||
| Centro di Riferimento Oncologico | Pordenone | 33081 | Italy | Details | ||
| Regina Elena Institute for Cancer Research | Rome | 00144 | Italy | Details | ||
| ASST Bergamo Ovest- ospedale di Treviglio | Treviglio | 24047 | Italy | Details | ||
| National Cancer Center Hospital East | Chiba | 277-0882 | Japan | Details | ||
| National Hospital Organization Shikoku Cancer Center | Ehime | 791-0280 | Japan | Details | ||
| Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
| Kurume University Hospital | Fukuoka | 830-0011 | Japan | Details | ||
| National Hospital Organization Himeji Medical Center | Hyogo | 670-8520 | Japan | Details | ||
| Hyogo Cancer Center | Hyogo | 673-8558 | Japan | Details | ||
| Kanazawa University Hospital | Ishikawa | 920-8641 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-0815 | Japan | Details | ||
| Sendai Kousei Hospital | Miyagi | 981-0914 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Osaka Metropolitan University Hospital | Osaka | 545-8586 | Japan | Details | ||
| Osaka Medical and Pharmaceutical University Hospital | Osaka | 569-8686 | Japan | Details | ||
| Kindai University Hospital | Osaka | 589-8511 | Japan | Details | ||
| National Hospital Organization Kinki Chuo Chest Medical Center | Osaka | 591-8555 | Japan | Details | ||
| Saitama Medical University | Saitama | 350-1298 | Japan | Details | ||
| SMG - SNU Boramae Medical Center | Dongjak-Gu | 07061 | Korea, Republic of | Details | ||
| Samsung Medical Center | Gangnam-Gu | 6351 | Korea, Republic of | Details | ||
| National Cancer Center | Goyang | 410769 | Korea, Republic of | Details | ||
| Chungbuk National University Hospital | Heungdeok-Gu | 361-711 | Korea, Republic of | Details | ||
| Inha University Hospital | Incheon | 22332 | Korea, Republic of | Details | ||
| Gachon University Gil Medical Center | Inchon | 21565 | Korea, Republic of | Details | ||
| Kosin University Gospel Hospital | Seo-gu | 49267 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| The Catholic University of Korea, Seoul St. Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Ajou University Hospital | Suwon-si | 16499 | Korea, Republic of | Details | ||
| The Catholic University of Korea, Saint Vincent's Hospital | Suwon | 16247 | Korea, Republic of | Details | ||
| Health Pharma Professional Research S.A. de C.V. | Mexico | 3100 | Mexico | Details | ||
| Hospital Universitario Dr. Jose Eleuterio Gonzalez | Mitras Centro | 64460 | Mexico | Details | ||
| Oaxaca Site Management Organization | Oaxaca | 68000 | Mexico | Details | ||
| Centro de Investigacion Clinica de Oaxaca | Oaxaca | 68020 | Mexico | Details | ||
| Clinical Medical Research SC. | Orizaba Centro | 94300 | Mexico | Details | ||
| Clinica Integral Internacional de Oncologia S de RL de CV | Puebla | 72530 | Mexico | Details | ||
| FAICIC Clínical Research | Veracruz | 91900 | Mexico | Details | ||
| Amphia Ziekenhuis | Breda | 4818 CK | Netherlands | Details | ||
| Ziekenhuis Gelderse Vallei | Ede | 6716 RP | Netherlands | Details | ||
| Universitair Medisch Centrum Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| Ziekenhuis St Jansdal | Harderwijk | 3844 DG | Netherlands | Details | ||
| TweeSteden Ziekenhuis | Tilburg | Netherlands | Details | |||
| Hospital Prof. Doutor Fernando Fonseca | Amadora | 2720276 | Portugal | Details | ||
| Instituto Português de Oncologia de Lisboa Francisco Gentil | Lisboa | 1089 | Portugal | Details | ||
| Fundacao Champalimaud | Lisboa | 1400-038 | Portugal | Details | ||
| Centro Hospitalar Universitário Lisboa Norte - Hospital Pulido Valente | Lisboa | Portugal | Details | |||
| Hospital Beatriz Angelo. Hospital de Loures. | Lisbon | 2674-514 | Portugal | Details | ||
| Centro Hospitalar Universitario Sao Joao, EPE | Porto | 4202-451 | Portugal | Details | ||
| Unidade Local de Saude de Matosinhos EPE - Hospital Pedro Hispano SA | Senhora da Hora | 4464-513 | Portugal | Details | ||
| Raffles Hospital | Singapore | 188770 | Singapore | Details | ||
| Tang Tock Seng Hospital | Singapore | 308433 | Singapore | Details | ||
| Hospital Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hospital de la Santa Creu i de Sant Pau | Barcelona | 08041 | Spain | Details | ||
| Hospital Universitari Dexeus (USP Institut Universitari Dexeus/Hospital Universitari Quiron Dexeus) | Barcelona | 8028 | Spain | Details | ||
| Hospital Universitari Vall D'Hebron | Barcelona | 8035 | Spain | Details | ||
| Hospital Parc Tauli | Barcelona | 8208 | Spain | Details | ||
| Hospital Universitario Reina Sofia | Cordoba | 14004 | Spain | Details | ||
| Hospital Doctor Josep Trueta | Girona | 17007 | Spain | Details | ||
| Hospital Universitario de Jaen | Jaen | 23007 | Spain | Details | ||
| Hospital Universitario de Canarias | Las Palmas de G.C. | 35016 | Spain | Details | ||
| Hospital Universitario Fundacion Jimenez Diaz | Madrid | 28020 | Spain | Details | ||
| Clinica Universidad de Navarra | Madrid | 28027 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| Hospital Universitario Puerta de Hierro de Majadahonda | Majadahonda | 28222 | Spain | Details | ||
| Hospital Sant Joan de Reus | Reus | 43204 | Spain | Details | ||
| Hospital Regional Universitario de Malaga | Rincon de la Victoria | 29011 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Seville | 41014 | Spain | Details | ||
| Instituto Valenciano De Oncologia (IVO) | Valencia | 46009 | Spain | Details | ||
| Hospital Universitari i Politecnic La Fe | Valencia | 46015 | Spain | Details | ||
| Hospital Vithas Valencia 9 de Octubre | Valencia | 46015 | Spain | Details | ||
| Changhua Christian Hospital | Changhua City | 500-06 | Taiwan | Details | ||
| E-DA Hospital | Kaohsiung City | 824 | Taiwan | Details | ||
| Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung | 807 | Taiwan | Details | ||
| Chang Gung Memorial Hospital Kaohsiung | Kaohsiung | 83301 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 70403 | Taiwan | Details | ||
| Chi Mei Hospital, Liouying | Tainan | Taiwan | Details | |||
| National Taiwan University Hospital | Taipei City | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 10002 | Taiwan | Details | ||
| Chang Gung Memorial Hospital Linkou Branch of the Chang Gung Medical Foundation | Taoyuan City | 33305 | Taiwan | Details | ||
| Ankara Bilkent Sehir Hastanesi | Ankara | 06550 | Turkey | Details | ||
| Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi | Ankara | 6200 | Turkey | Details | ||
| Trakya University Faculty of Medicine | Edirne | 22030 | Turkey | Details | ||
| Istanbul University Cerrahpasa Medical Faculty Hospital | Fatih | 34098 | Turkey | Details | ||
| Goztepe Prof. Dr. Suleyman Yalcın Sehir Hastanesi | Istanbul | 34093 | Turkey | Details | ||
| Medipol Mega University Hospital | Istanbul | Turkey | Details | |||
| Acibadem Mehmet Ali Aydinlar Universitesi Atakent Hastanesi | Kaakaekmece | 34303 | Turkey | Details | ||
| Turgut Ozal Medical Faculty | Malatya | 44300 | Turkey | Details | ||
| Colchester General Hospital | Colchester | CO4 5JL | United Kingdom | Details | ||
| St Bartholomew's Hospital, Barts Health NHS Trust | London | EC1A 7BE | United Kingdom | Details | ||
| The Christie NHS Foundation Trust, Department of Medical Oncology | Manchester | M20 4BX | United Kingdom | Details | ||
| University Hospital Southampton Nhs Foundation Trust | Southampton | SO16 6YD | United Kingdom | Details |