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| NCT ID | NCT05508867 |
| Title | A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Physician's Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory Classical Hodgkin Lymphoma (MK-4280A-008) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | POL | ISR | GBR | FRA | ESP | DEU | CZE | CHE | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The University of Arizona Cancer Center - North Campus ( Site 2216) | Tucson | Arizona | 85719 | United States | Details | |
| UCLA Hematology/Oncology - Santa Monica ( Site 2208) | Los Angeles | California | 90404 | United States | Details | |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA-Hematology and Medical Oncology ( Site | Torrance | California | 90502 | United States | Details | |
| Moffitt Cancer Center ( Site 2200) | Tampa | Florida | 33612 | United States | Details | |
| University of Kentucky Chandler Medical Center ( Site 2201) | Lexington | Kentucky | 40536 | United States | Details | |
| University of Maryland-Greenebaum Comprehensive Cancer Center ( Site 2210) | Baltimore | Maryland | 21201 | United States | Details | |
| Johns Hopkins University-The Sidney Kimmel Comprehensive Cancer Center ( Site 2206) | Baltimore | Maryland | 21231 | United States | Details | |
| University of Michigan ( Site 2215) | Ann Arbor | Michigan | 48109 | United States | Details | |
| Cancer and Hematology Centers of Western Michigan ( Site 2222) | Grand Rapids | Michigan | 49503 | United States | Details | |
| Rutgers Cancer Institute of New Jersey ( Site 2217) | New Brunswick | New Jersey | 08903 | United States | Details | |
| Roswell Park Cancer Institute ( Site 2220) | Buffalo | New York | 14263 | United States | Details | |
| University Hospitals Cleveland Medical Center ( Site 2214) | Cleveland | Ohio | 44106 | United States | Details | |
| Cleveland Clinic-Taussig Cancer Center ( Site 2203) | Cleveland | Ohio | 44195 | United States | Details | |
| AHN West Penn Hospital ( Site 2213) | Pittsburgh | Pennsylvania | 15224 | United States | Details | |
| UPMC Hillman Cancer Center ( Site 2205) | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Fred Hutchinson Cancer Center ( Site 2212) | Seattle | Washington | 98109 | United States | Details | |
| Hospital Aleman-oncohematologic diseases ( Site 2302) | Buenos Aires | C1118AAT | Argentina | Details | ||
| Fundacion Centro Oncologico de Integración Regional-Medical Oncology ( Site 2301) | Mendoza | M5500AYB | Argentina | Details | ||
| The Townsville Hospital ( Site 0006) | Townsville | Queensland | 4814 | Australia | Details | |
| Royal Adelaide Hospital ( Site 0005) | Adelaide | South Australia | 5000 | Australia | Details | |
| Western Health-Sunshine & Footscray Hospitals-Cancer Services-Cancer Research ( Site 0002) | St Albans | Victoria | 3021 | Australia | Details | |
| Royal Perth Hospital-Haematology ( Site 0004) | Perth | Western Australia | 6000 | Australia | Details | |
| UZ Leuven-Hematology ( Site 0101) | Leuven | Vlaams-Brabant | 3000 | Belgium | Details | |
| Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godi | Namur | 5530 | Belgium | Details | ||
| Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0202) | Barretos | Sao Paulo | 14784400 | Brazil | Details | |
| Hospital Paulistano-Americas Oncologia ( Site 0207) | Sao Paulo | 01321-001 | Brazil | Details | ||
| Cross Cancer Institute ( Site 0313) | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Princess Margaret Cancer Centre ( Site 0310) | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Jewish General Hospital ( Site 0309) | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| McGill University Health Centre ( Site 0314) | Montréal | Quebec | H4A 3J1 | Canada | Details | |
| FALP-UIDO ( Site 0400) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
| Clínica Inmunocel ( Site 0407) | Santiago | Region M. De Santiago | 7580206 | Chile | Details | |
| Anhui Provincial Cancer Hospital ( Site 0501) | Hefei | Anhui | 230031 | China | Details | |
| Beijing Hospital ( Site 0514) | Beijing | Beijing | 100005 | China | Details | |
| Peking University Third Hospital-Hematology ( Site 0519) | Beijing | Beijing | 100091 | China | Details | |
| The First Affiliated hospital of Xiamen University ( Site 0512) | Xiamen | Fujian | 361003 | China | Details | |
| Sun Yat-sen University Cancer Center ( Site 0500) | Guangzhou | Guangdong | 510060 | China | Details | |
| Henan Cancer Hospital ( Site 0515) | Zhengzhou | Henan | 450008 | China | Details | |
| Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 0509) | Wuhan | Hubei | 430010 | China | Details | |
| Xiangya Hospital Central South University ( Site 0513) | Changsha | Hunan | 410008 | China | Details | |
| Hunan Cancer Hospital ( Site 0503) | Changsha | Hunan | 410013 | China | Details | |
| The First Hospital of Jilin University-Hematology ( Site 0516) | Changchun | Jilin | 130021 | China | Details | |
| Fudan University Shanghai Cancer Center ( Site 0520) | Shanghai | Shanghai | 200032 | China | Details | |
| West China Hospital of Sichuan University-Head and Neck Oncology ( Site 0502) | Cheng Du | Sichuan | 610041 | China | Details | |
| Tianjin Medical University Cancer Institute & Hospital-lymphoma ( Site 0506) | Tianjin | Tianjin | 300060 | China | Details | |
| Zhejiang Cancer Hospital ( Site 0510) | Hangzhou | Zhejiang | 310022 | China | Details | |
| Ningbo First Hospital ( Site 0518) | Ningbo | Zhejiang | 315010 | China | Details | |
| Fakultní nemocnice Brno Bohunice-Interni hematologicka a onkologicka klinika ( Site 0901) | Brno | Brno-mesto | 625 00 | Czechia | Details | |
| Fakultni nemocnice Hradec Kralove-IV. interni hematologicka klinika ( Site 0902) | Hradec Kralove | 500 05 | Czechia | Details | ||
| Vseobecna fakultni nemocnice v Praze-I. Interní klinika - klinika hematologie ( Site 0903) | Praha 2 | 128 08 | Czechia | Details | ||
| Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou-haematology ( Site 0707) | Rennes | Bretagne | 35033 | France | Details | |
| Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE ( Site 0706) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren ( Site 0704) | Limoges | Haute-Vienne | 87042 | France | Details | |
| Institut Curie - site Saint-Cloud ( Site 0708) | Saint-Cloud | Hauts-de-Seine | 92210 | France | Details | |
| CENTRE LEON BERARD-Medical oncology ( Site 0703) | Lyon | Rhone | 69008 | France | Details | |
| HENRI MONDOR HOSPITAL ( Site 0702) | Créteil | Seine-et-Marne | 94000 | France | Details | |
| Klinikum Stuttgart - Katharinenhospital ( Site 0804) | Stuttgart | Baden-Wurttemberg | 70174 | Germany | Details | |
| Universitaetsklinikum Ulm-Department of Internal Medicine III ( Site 0805) | Ulm | Baden-Wurttemberg | 89081 | Germany | Details | |
| Universitaetsklinikum Essen ( Site 0807) | Essen | Nordrhein-Westfalen | 45147 | Germany | Details | |
| Universitaetsklinikum Koeln-Klinik I für Innere Medizin ( Site 0801) | Köln | Nordrhein-Westfalen | 50937 | Germany | Details | |
| Universitätsklinikum Münster - Albert Schweitzer Campus ( Site 0806) | Münster | Nordrhein-Westfalen | 48149 | Germany | Details | |
| Universitaetsklinikum Carl Gustav Carus Dresden-University Cancer Center Early Clinical Trial Unit ( | Dresden | Sachsen | 01307 | Germany | Details | |
| Universitätsklinikum Leipzig ( Site 0803) | Leipzig | Sachsen | 04103 | Germany | Details | |
| Rambam Health Care Campus ( Site 1004) | Haifa | 3109601 | Israel | Details | ||
| Carmel Hospital ( Site 1007) | Haifa | 3436212 | Israel | Details | ||
| Hadassah Medical Center-Hemato-Oncology ( Site 1000) | Jerusalem | 9112001 | Israel | Details | ||
| Rabin Medical Center-Hemato-Oncology ( Site 1001) | Petah-Tikva | 4910021 | Israel | Details | ||
| Sheba Medical Center-Hemato Oncology ( Site 1005) | Ramat Gan | 5265601 | Israel | Details | ||
| Sourasky Medical Center ( Site 1002) | Tel Aviv | 6423906 | Israel | Details | ||
| Pusan National University Hospital-Internal Medicine ( Site 1704) | Busan | Pusan-Kwangyokshi | 49241 | Korea, Republic of | Details | |
| Seoul National University Hospital ( Site 1701) | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1702) | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center-Department of Oncology ( Site 1703) | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center ( Site 1700) | Seoul | 06351 | Korea, Republic of | Details | ||
| Centro de Infusion Superare ( Site 2503) | Ciudad de México | Distrito Federal | 03100 | Mexico | Details | |
| Unidad Médica Onco-hematológica ( Site 2507) | Puebla | 72424 | Mexico | Details | ||
| Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckieg-Klinika Hematologii, Nowotworów Krwi i | Wrocław | Dolnoslaskie | 50-556 | Poland | Details | |
| Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 1406) | Kraków | Malopolskie | 31-826 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Kilinka Onkologii I Hematologii ( Site | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Uniwersyteckie Centrum Kliniczne-Klinika Hematologii i Transplantologii ( Site 1402) | Gdansk | Pomorskie | 80-214 | Poland | Details | |
| Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Hematologii i Transplantacji S | Kielce | Swietokrzyskie | 25-734 | Poland | Details | |
| Hospital Universitario Marqués de Valdecilla ( Site 1805) | Santander | Cantabria | 39008 | Spain | Details | |
| Hospital Universitari Vall d'Hebron ( Site 1803) | Barcelona | Cataluna | 08035 | Spain | Details | |
| CHUAC-Complejo Hospitalario Universitario A Coruña ( Site 1812) | A Coruña | La Coruna | 15006 | Spain | Details | |
| Hospital Insular de Gran Canaria-Oncology ( Site 1807) | Las Palmas de Gran Canaria | Las Palmas | 35016 | Spain | Details | |
| Hospital General Universitario de Alicante ( Site 1806) | Alicante | 03010 | Spain | Details | ||
| Hospital Universitario 12 de Octubre-Hemathology and hemotherapy ( Site 1810) | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario Virgen de la Victoria ( Site 1808) | Malaga | 29010 | Spain | Details | ||
| Hospital Universitario de Salamanca - Complejo Asistencial U-Servicio de Hematologia ( Site 1801) | Salamanca | 37007 | Spain | Details | ||
| Skånes Universitetssjukhus Lund ( Site 1901) | Lund | Skane Lan | 22185 | Sweden | Details | |
| Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 1900) | Uppsala | Uppsala Lan | 751 85 | Sweden | Details | |
| Ospedale Regionale Bellinzona e Valli-IOSI ( Site 1600) | Bellinzona | Ticino | 6501 | Switzerland | Details | |
| Mega Medipol-Hematology ( Site 2005) | Stanbul | Istanbul | 34214 | Turkey | Details | |
| Ankara Universitesi Tip Fakultesi Hastanesi-hematology ( Site 2000) | Ankara | 06100 | Turkey | Details | ||
| Hacettepe Universite Hastaneleri-Department of Hematology ( Site 2006) | Ankara | 06230 | Turkey | Details | ||
| Antalya Egitim ve Arastırma Hastanesi ( Site 2011) | Antalya | 07100 | Turkey | Details | ||
| Ege Universitesi Hastanesi ( Site 2001) | İzmir | 35100 | Turkey | Details | ||
| Kocaeli Üniversitesi-Hematology ( Site 2009) | Kocaeli | 41380 | Turkey | Details | ||
| Derriford Hospital ( Site 2107) | Plymouth | Devon | Pl6 8DH | United Kingdom | Details | |
| The Beatson West of Scotland Cancer Centre ( Site 2110) | Glasgow | Glasgow City | G12 0YN | United Kingdom | Details | |
| St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 2105) | London | London, City Of | EC1A 7BE | United Kingdom | Details | |
| GenesisCare - Oxford ( Site 2104) | Oxford | Oxfordshire | OX4 6LB | United Kingdom | Details | |
| St James's University Hospital ( Site 2109) | Leeds | LS9 7TF | United Kingdom | Details | ||
| Leicester Royal Infirmary ( Site 2100) | Leicester | LE1 5WW | United Kingdom | Details | ||
| Clatterbridge Cancer Centre - Liverpool-Heamatology ( Site 2108) | Liverpool | L7 8YA | United Kingdom | Details |