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| NCT ID | NCT05566795 |
| Title | DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Day One Biopharmaceuticals, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | child |
| Covered Countries | USA | SWE | SVN | NZL | NOR | NLD | ITA | ISR | IRL | HUN | GRC | GBR | FRA | FIN | ESP | DNK | DEU | CZE | CHE | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Children's of Alabama | RECRUITING | Birmingham | Alabama | 35233 | United States | Details |
| Phoenix Children's Hospital | RECRUITING | Phoenix | Arizona | 85016 | United States | Details |
| Children's Hospital Los Angeles | RECRUITING | Los Angeles | California | 90027 | United States | Details |
| UCSF Benioff Children's Hospital | RECRUITING | San Francisco | California | 94158 | United States | Details |
| Children's Hospital Colorado | RECRUITING | Aurora | Colorado | 80045 | United States | Details |
| Children's National Medical Center | RECRUITING | Washington | District of Columbia | 20010 | United States | Details |
| Arnold Palmer Hospital for Children | RECRUITING | Orlando | Florida | 32806 | United States | Details |
| Children's Healthcare of Atlanta | RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Ann & Robert H. Lurie Children's Hospital of Chicago | RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| Riley Hospital for Children at Indiana University Health | RECRUITING | Indianapolis | Indiana | 46202 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| University of Michigan - - C.S. Mott Children's Hospital | RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| St. Louis Children's Hospital | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| New York University Langone Health | RECRUITING | New York | New York | 10016 | United States | Details |
| University of Rochester | RECRUITING | Rochester | New York | 14642 | United States | Details |
| Duke Cancer Institute | RECRUITING | Durham | North Carolina | 27705 | United States | Details |
| Cleveland Clinic Main Campus | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| University of Texas Southwestern Medical Center | RECRUITING | Dallas | Texas | 75390 | United States | Details |
| Texas Children's Hospital | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Seattle Children's Hospital | RECRUITING | Seattle | Washington | 98105 | United States | Details |
| Children's Health Queensland Hospital and Health Service | RECRUITING | South Brisbane | Queensland | 4101 | Australia | Details |
| Perth Children's Hospital | RECRUITING | Nedlands | 6009 | Australia | Details | |
| Women's and Children's Health Network | RECRUITING | North Adelaide | 5006 | Australia | Details | |
| The Royal Children's Hospital - Children's Cancer Centre | RECRUITING | Parkville | 3052 | Australia | Details | |
| Sydney Children's Hospital - Randwick | RECRUITING | Randwick | 2031 | Australia | Details | |
| Children's Hospital at Westmead | RECRUITING | Westmead | 2145 | Australia | Details | |
| Medizinische Universität Innsbruck | RECRUITING | Innsbruck | Tirol | 6020 | Austria | Details |
| Medizinische Universität Wien | RECRUITING | Wien | 1090 | Austria | Details | |
| Cliniques Universitaires Saint-Luc | RECRUITING | Brussel | 1200 | Belgium | Details | |
| Universitair Ziekenhuis Gent | RECRUITING | Ghent | 9000 | Belgium | Details | |
| Universitair Ziekenhuis Leuven - Campus Gasthuisberg | RECRUITING | Leuven | 3000 | Belgium | Details | |
| Alberta Children's Hospital | RECRUITING | Calgary | Alberta | T3B 6A8 | Canada | Details |
| British Columbia Children's Hospital | RECRUITING | Vancouver | British Columbia | V6H 3N1 | Canada | Details |
| Children's Hospital of Eastern Ontario | RECRUITING | Ottawa | Ontario | K1H 8L1 | Canada | Details |
| CHU Sainte-Justine | RECRUITING | Montréal | Quebec | H3T IC5 | Canada | Details |
| The Montreal Children's Hospital | RECRUITING | Montréal | Quebec | H4A 3J1 | Canada | Details |
| Centre Hospitalier de l'Université Laval et Centre Mère-Enfant Soleil | RECRUITING | Québec | G1V 4G2 | Canada | Details | |
| SickKids - The Hospital for Sick Children | RECRUITING | Toronto | M5G 1X8 | Canada | Details | |
| Fakultní Nemocnice Brno - D?tská Nemocnice | RECRUITING | Brno | 625 00 | Czechia | Details | |
| Motol University Hospital | RECRUITING | Prague | 5 150 06 | Czechia | Details | |
| Aarhus Universitetshospital | RECRUITING | Aarhus | Midtjylland | 8200 | Denmark | Details |
| Rigshospitalet | RECRUITING | Copenhagen | 2100 | Denmark | Details | |
| Helsingin yliopistollinen sairaala (HUS) | RECRUITING | Helsinki | FI-00290 | Finland | Details | |
| Tampereen Yliopistollinen Sairaala | RECRUITING | Tampere | 33520 | Finland | Details | |
| Centre de Lutte contre le Cancer - Centre Oscar Lambret | RECRUITING | Lille | 59020 | France | Details | |
| Centre Léon Bérard | RECRUITING | Lyon | 69008 | France | Details | |
| Hôpital de la Timone | RECRUITING | Marseille | 13005 | France | Details | |
| Institut Curie | RECRUITING | Paris | 75248 | France | Details | |
| Gustave Roussy | RECRUITING | Villejuif | 94805 | France | Details | |
| Universitätsklinikum Freiburg | RECRUITING | Freiburg | Baden-Württemberg | 79106 | Germany | Details |
| Universitätsklinikum Augsburg | RECRUITING | Augsburg | Bayern | 86156 | Germany | Details |
| Universitätsklinikum Erlangen | RECRUITING | Erlangen | Bayern | 91054 | Germany | Details |
| Universitätsklinikum Würzburg | RECRUITING | Würzburg | Bayern | 97080 | Germany | Details |
| Universitätsklinikum Frankfurt | RECRUITING | Frankfurt | Hessen | 60590 | Germany | Details |
| Medizinische Hochschule Hannover | RECRUITING | Hannover | Niedersachsen | 30625 | Germany | Details |
| Universitätsklinikum Leipzig | RECRUITING | Leipzig | Sachsen | 4103 | Germany | Details |
| Charité Universitätsmedizin Berlin | RECRUITING | Berlin | 13353 | Germany | Details | |
| Evangelische Klinikum Bethel (EvKB) | RECRUITING | Bielefeld | 33617 | Germany | Details | |
| Universitätsklinikum Hamburg-Eppendorf | RECRUITING | Hamburg | 20246 | Germany | Details | |
| Universitätsklinikum Heidelberg | RECRUITING | Heidelberg | 69120 | Germany | Details | |
| Universitätsklinikum Tübingen | RECRUITING | Tübingen | 72076 | Germany | Details | |
| Aghia Sofia General Children's Hospital | RECRUITING | Athens | 11527 | Greece | Details | |
| Athens General Children's Hospital | RECRUITING | Athens | 11527 | Greece | Details | |
| Semmelweis Egyetem Tűzoltó utcai II. Sz. Gyermekgyógyászati Kliniká | RECRUITING | Budapest | 1094 | Hungary | Details | |
| Children's Health Ireland at Crumlin | RECRUITING | Crumlin | Dublin | D12 N512 | Ireland | Details |
| Schneider Children's Medical Center of Israel | RECRUITING | Petah tikva | 49202 | Israel | Details | |
| The Edmond and Lily Safra Children's Hospital | RECRUITING | Ramat Gan | 5265601 | Israel | Details | |
| Fondazione IRCCS - Istituto Nazionale dei Tumori | RECRUITING | Milano | Milan | 20133 | Italy | Details |
| Ospedale Pediatrico Bambino Gesù | RECRUITING | Roma | Rome | 00165 | Italy | Details |
| Ospedale Infantile Regina Margherita | RECRUITING | Torino | Turin | 10126 | Italy | Details |
| Azienda Universitaria Ospedaliera Consorziale - Policlinico di Bari | RECRUITING | Bari | 70124 | Italy | Details | |
| Istituto Giannina Gaslini | RECRUITING | Genova | 16147 | Italy | Details | |
| Azienda Ospedaliera di Rilievo Nazional Santobono Pausilipon | RECRUITING | Napoli | 80131 | Italy | Details | |
| Azienda Ospedale Università di Padova | RECRUITING | Padova | 35128 | Italy | Details | |
| Azienda Sanitaria Universitaria Friuli Centrale - P.O. Santa Maria della Misericordia | RECRUITING | Udine | 33100 | Italy | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Severance Hospital | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Prinses Maxima Centrum Kinderoncologie | RECRUITING | Utrecht | 3584 CS | Netherlands | Details | |
| Starship Paediatric Blood & Cancer Center | RECRUITING | Grafton | 1023 | New Zealand | Details | |
| Universitetssykehuset Nord-Norge - Tromsø | RECRUITING | Tromsø | Troms | 9038 | Norway | Details |
| Oslo Universitetssykehus | RECRUITING | Oslo | 372 | Norway | Details | |
| SingHealth Group - KK Women's and Children's Hospital | RECRUITING | Singapore | 229899 | Singapore | Details | |
| Univerzitetni Klinini Center Ljubljana | RECRUITING | Ljubljana | 1000 | Slovenia | Details | |
| Hospital Universitario Cruces | RECRUITING | Barakaldo | 48903 | Spain | Details | |
| Hospital Universitari Vall d'Hebrón | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Sant Joan de Déu Barcelona | RECRUITING | Barcelona | 08950 | Spain | Details | |
| Hospital Infantil Universitario Niño Jesús | RECRUITING | Madrid | 28009 | Spain | Details | |
| Hospital Universitario La Paz | RECRUITING | Madrid | 28046 | Spain | Details | |
| Hospital Universitario Virgen del Rocío | RECRUITING | Sevilla | 41013 | Spain | Details | |
| Hospital Universitari i Politècnic La Fe | RECRUITING | Valencia | 46026 | Spain | Details | |
| Drottning Silvias barn- och ungdomssjukhus | RECRUITING | Göteborg | 416 85 | Sweden | Details | |
| Skånes Universitetssjukhus - Lund | RECRUITING | Lund | 221 85 | Sweden | Details | |
| Astrid Lindgrens Barnsjukhus Solna | RECRUITING | Stockholm | 171 77 | Sweden | Details | |
| Centre Hospitalier Universitaire Vaudois Lausanne | RECRUITING | Lausanne | 1011 | Switzerland | Details | |
| Universitaets - Kinderspital Zürich | RECRUITING | Zurich | 8032 | Switzerland | Details | |
| Birmingham Women's and Children's NHS Foundation Trust | RECRUITING | Birmingham | England | B4 6NH | United Kingdom | Details |
| Leeds Teaching Hospital NHS Trust | RECRUITING | Leeds | England | LS1 3EX | United Kingdom | Details |
| Alder Hey Children's NHS Foundation Trust | RECRUITING | Liverpool | England | L12 2AP | United Kingdom | Details |
| Manchester University NHS Foundation Trust | RECRUITING | Manchester | England | M13 PWL | United Kingdom | Details |
| The Newcastle Upon Tyne Hospitals NHS Foundation Trust | RECRUITING | Newcastle Upon Tyne | England | NE1 4LP | United Kingdom | Details |
| Great Ormond Street Hospital for Children | RECRUITING | Oxford | England | WC1N 3JH | United Kingdom | Details |
| Royal Belfast Hospital for Sick Children | RECRUITING | Belfast | Northern Ireland | BT9 7AB | United Kingdom | Details |
| NHS Greater Glasgow and Clyde | RECRUITING | Glasgow | Scotland | G51 4TF | United Kingdom | Details |
| The Royal Marsden NHS Foundation Trust | RECRUITING | Sutton | Surrey | SM2 5PT | United Kingdom | Details |
| University Hospitals Bristol and Weston NHS Foundation Trust | RECRUITING | Bristol | BS2 8HW | United Kingdom | Details | |
| Cambridge University Hospitals NHS Foundation Trust | RECRUITING | Cambridge | CB2 0QQ | United Kingdom | Details |