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NCT ID NCT05609968
Title Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) >=50% (MK-3475-D46)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme LLC
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | TUR | ROU | POL | LVA | LTU | ITA | ISR | GRC | GBR | EST | DEU | CAN | BRA | AUS

Facility Status City State Zip Country Details
Infirmary Cancer Care ( Site 0418) RECRUITING Mobile Alabama 36607 United States Details
Clermont Oncology Center ( Site 0421) RECRUITING Clermont Florida 34711 United States Details
University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 0417) RECRUITING Miami Florida 33136 United States Details
Mid Florida Hematology and Oncology Center ( Site 0416) RECRUITING Orange City Florida 32763 United States Details
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0407) RECRUITING Marietta Georgia 30060 United States Details
Our Lady of the Lake RMC ( Site 0424) RECRUITING Baton Rouge Louisiana 70808 United States Details
Henry Ford Hospital ( Site 0412) RECRUITING Detroit Michigan 48202 United States Details
Allina Health Cancer Institute - Abbott Northwestern Hospital ( Site 0425) RECRUITING Minneapolis Minnesota 55407 United States Details
White Plains Hospital-Center for Cancer Care ( Site 0403) RECRUITING White Plains New York 10601 United States Details
Kaiser Permanente Northwest-Central Interstate--Oncology ( Site 0408) RECRUITING Portland Oregon 97227 United States Details
Houston Methodist Hospital ( Site 0419) RECRUITING Houston Texas 77030 United States Details
Central Texas Veterans health care ( Site 0414) RECRUITING Temple Texas 76504 United States Details
Orange Hospital-Clinical Trials Unit ( Site 0600) RECRUITING Orange New South Wales 2800 Australia Details
Cancer Research SA-St Andrews Hospital ( Site 0603) RECRUITING Adelaide South Australia 5000 Australia Details
Frankston Hospital-Oncology and Haematology ( Site 0601) RECRUITING Frankston Victoria 3199 Australia Details
CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA ( Site 0320) RECRUITING Fortaleza Ceara 60336232 Brazil Details
Hospital Tacchini ( Site 0322) RECRUITING Bento Goncalves Rio Grande Do Sul 95700-068 Brazil Details
Hospital da Cidade de Passo Fundo ( Site 0321) RECRUITING Passo Fundo Rio Grande Do Sul 99010-260 Brazil Details
Instituto de Oncologia Saint Gallen ( Site 0317) RECRUITING Santa Cruz do Sul Rio Grande Do Sul 96830-180 Brazil Details
Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0318) RECRUITING Barretos Sao Paulo 14784400 Brazil Details
A. C. Camargo Cancer Center ( Site 0324) RECRUITING Sao Paulo 01509-010 Brazil Details
BC Cancer Abbotsford-Medical Oncology ( Site 0433) RECRUITING Abbotsford British Columbia V2S 0C2 Canada Details
Southlake Regional Health Centre-Oncology Clinical Trials ( Site 0435) RECRUITING Newmarket Ontario L3Y 2P9 Canada Details
Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre ( Site 0430) RECRUITING Greenfield Park Quebec J4V 2H1 Canada Details
St. Marys Hospital Center-Oncology ( Site 0434) RECRUITING Montreal Quebec H3T 1M5 Canada Details
Centre integre universitaire de sante et de services sociaux-oncology ( Site 0431) RECRUITING Trois-Rivières Quebec G8Z 3R9 Canada Details
Oncovida ( Site 0334) RECRUITING Santiago Region M. De Santiago 7510032 Chile Details
Pontificia Universidad Catolica de Chile-Centro del Cáncer ( Site 0332) RECRUITING Santiago Region M. De Santiago 8330032 Chile Details
Second Affiliated hospital of Anhui Medical University ( Site 0126) RECRUITING Hefei Anhui 230000 China Details
Anhui Provincial Hospital ( Site 0136) RECRUITING Hefei Anhui 230071 China Details
Beijing Cancer hospital ( Site 0104) RECRUITING Beijing Beijing 100142 China Details
Beijing Peking Union Medical College Hospital-pneumology department ( Site 0106) RECRUITING Beijing Beijing 100730 China Details
Beijing Chest Hospital,Capital Medical University ( Site 0105) RECRUITING Beijing Beijing 101149 China Details
Chongqing University Cancer Hospital-Medical Oncology ( Site 0130) RECRUITING Chongqing Chongqing 400030 China Details
Fujian Provincial Cancer Hospital ( Site 0131) RECRUITING Fuzhou Fujian 350014 China Details
The First Affiliated hospital of Xiamen University ( Site 0132) RECRUITING Xiamen Fujian 361003 China Details
Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( RECRUITING Guangzhou Guangdong 510515 China Details
Guangxi Medical University Affiliated Tumor Hospital-Respiratory Oncology ( Site 0113) RECRUITING Nanning Guangxi 530021 China Details
Harbin Medical University Cancer Hospital ( Site 0119) RECRUITING Harbin Heilongjiang 150081 China Details
Henan Cancer Hospital ( Site 0127) RECRUITING Zhengzhou Henan 450008 China Details
Tongji Hospital Tongji Medical,Science & Technology ( Site 0116) RECRUITING Wuhan Hubei 430000 China Details
Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 0115) RECRUITING Wuhan Hubei 430010 China Details
Hubei Cancer Hospital ( Site 0107) RECRUITING Wuhan Hubei 430079 China Details
Xiangya Hospital Central South University ( Site 0124) RECRUITING Changsha Hunan 410008 China Details
The Second Xiangya Hospital of Central South University ( Site 0135) RECRUITING Changsha Hunan 410011 China Details
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School ( Site 0112 RECRUITING NanJing Jiangsu 210000 China Details
Nantong Tumor Hospital-Medical Oncology ( Site 0122) RECRUITING Nantong Jiangsu 226361 China Details
The First Affliated Hospital of Suzhou University ( Site 0114) RECRUITING Suzhou Jiangsu 215000 China Details
The Second Affiliated Hospital of Nanchang University ( Site 0134) RECRUITING Nanchang Jiangxi 330006 China Details
The First Hospital of Jilin University ( Site 0117) RECRUITING Changchun Jilin 130021 China Details
Jilin Province Tumor Hospital ( Site 0118) RECRUITING Changchun Jilin 132000 China Details
The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 0133) RECRUITING Xi'an Shaanxi 710061 China Details
Jinan Central Hospital-oncology department ( Site 0121) RECRUITING Jinan Shandong 250013 China Details
LinYi Cancer Hospital ( Site 0120) RECRUITING Linyi Shandong 276001 China Details
Shanghai Chest Hospital ( Site 0101) RECRUITING Shanghai Shanghai 200030 China Details
Fudan University Shanghai Cancer Center-Oncology ( Site 0102) RECRUITING Shanghai Shanghai 200032 China Details
Huashan Hospital, Fudan University ( Site 0103) RECRUITING Shanghai Shanghai 200040 China Details
West China Hospital of Sichuan University ( Site 0129) RECRUITING Cheng Du Sichuan 610041 China Details
Sichuan Cancer hospital ( Site 0128) RECRUITING Chengdu Sichuan 610042 China Details
The First Affiliated Hospital, Zhejiang University ( Site 0109) RECRUITING Hangzhou Zhejiang 310006 China Details
Sir Run Run Shaw Hospital-Medical Oncology ( Site 0111) RECRUITING Hangzhou Zhejiang 310016 China Details
Zhejiang Cancer Hospital ( Site 0108) RECRUITING Hangzhou Zhejiang 310022 China Details
The Second Affiliated hospital of Zhejiang University school of medicine ( Site 0110) RECRUITING Hangzhou Zhejiang 310052 China Details
North Estonia Medical Centre Foundation-Chemotherapy ( Site 0621) RECRUITING Tallinn Harjumaa 13419 Estonia Details
Tartu University Hospital-Radiotherapy and oncology ( Site 0620) RECRUITING Tartu Tartumaa 50406 Estonia Details
Universitätsmedizin Mannheim ( Site 0654) RECRUITING Mannheim Baden-Wurttemberg 68167 Germany Details
Klinikum Kempten ( Site 0655) RECRUITING Kempten Bayern 87439 Germany Details
Klinikum Würzburg Mitte ( Site 0651) RECRUITING Wuerzburg Bayern 97074 Germany Details
Katholisches Klinikum Koblenz ( Site 0650) RECRUITING Koblenz Rheinland-Pfalz 56073 Germany Details
Krankenhaus Martha-Maria Halle-Dölau-Klinik für Innere Medizin II ( Site 0657) RECRUITING Halle Sachsen-Anhalt 06120 Germany Details
Vivantes Hospital Spandau-Klinik für Innere Medizin, Hämatologie, Onkologie und Gastroenterologie- ( RECRUITING Berlin 13585 Germany Details
Helios Klinikum Emil von Behring Berlin-Zehlendorf-Lungenklinik Heckeshorn ( Site 0653) RECRUITING Berlin 14165 Germany Details
Errikos Dunant Hospital Center-Fourth Department of Oncology and Clinical Trials Unit ( Site 0141) RECRUITING Athens Attiki 115 26 Greece Details
Sotiria Thoracic Diseases Hospital of Athens-3rd Dept of Internal Medicine, Oncology Unit ( Site 014 RECRUITING Athens Attiki 115 27 Greece Details
European Interbalkan Medical Center-Oncology Department ( Site 0142) RECRUITING Thessaloniki 57001 Greece Details
Shaare Zedek Medical Center-Oncology ( Site 0176) RECRUITING Jerusalem 9103102 Israel Details
Meir Medical Center-oncology ( Site 0171) RECRUITING KfarSaba 4428164 Israel Details
Rabin Medical Center-Oncology ( Site 0174) RECRUITING Petah Tikva 4941492 Israel Details
Sourasky Medical Center-Oncology ( Site 0175) RECRUITING Tel Aviv 6423906 Israel Details
Yitzhak Shamir Medical Center. ( Site 0179) RECRUITING Zerifin 70300 Israel Details
Azienda Ospedaliera S. Giovanni Addolorata-Oncologia Medica ( Site 0677) RECRUITING Roma Lazio 00185 Italy Details
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII ( Site 0674) RECRUITING Bergamo Lombardia 24127 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 0673) RECRUITING Milan Lombardia 20133 Italy Details
Azienda Ospedaliera Dei Colli-U.O.C Pneumologia Oncologica DH PNL ONC ( Site 0671) RECRUITING Naples Napoli 80131 Italy Details
Azienda Ospedaliera Universitaria Careggi-SOD ONCOLOGIA MEDICA ( Site 0675) RECRUITING Firenze Toscana 50134 Italy Details
Casa di Cura Dott. Pederzoli-LUNG-UNIT TORACIC ( Site 0670) RECRUITING Peschiera del Garda Verona 37019 Italy Details
Azienda Ospedaliero Universitaria di Parma-UO Oncologia Medica ( Site 0676) RECRUITING Parma 43126 Italy Details
Aichi Cancer Center Hospital ( Site 0018) RECRUITING Nagoya Aichi 464-8681 Japan Details
National Hospital Organization Shikoku Cancer Center ( Site 0008) RECRUITING Matsuyama Ehime 791-0280 Japan Details
Kurume University Hospital ( Site 0014) RECRUITING Kurume Fukuoka 830-0011 Japan Details
Takarazuka City Hospital ( Site 0015) RECRUITING Takarazuka Hyogo 665-0827 Japan Details
Kanazawa University Hospital ( Site 0019) RECRUITING Kanazawa Ishikawa 920-8641 Japan Details
Kanagawa cancer center ( Site 0016) RECRUITING Yokohama Kanagawa 241-8515 Japan Details
Miyagi Cancer Center ( Site 0001) RECRUITING Natori Miyagi 981-1293 Japan Details
Sendai Kousei Hospital ( Site 0012) RECRUITING Sendai Miyagi 981-0914 Japan Details
Niigata Cancer Center Hospital ( Site 0017) RECRUITING Niigata-shi Niigata 951-8566 Japan Details
Kurashiki Central Hospital ( Site 0011) RECRUITING Kurashiki Okayama 710-8602 Japan Details
Kansai Medical University Hospital ( Site 0005) RECRUITING Hirakata Osaka 573-1191 Japan Details
Kindai University Hospital- Osakasayama Campus ( Site 0013) RECRUITING Osaka-sayama Osaka 589-8511 Japan Details
Saitama Prefectural Cancer Center ( Site 0002) RECRUITING Ina-machi Saitama 362-0806 Japan Details
Shizuoka Cancer Center ( Site 0004) RECRUITING Nagaizumi-cho,Sunto-gun Shizuoka 411-8777 Japan Details
National Hospital Organization Kyushu Medical Center ( Site 0009) RECRUITING Fukuoka 810-8563 Japan Details
Kyushu University Hospital ( Site 0010) RECRUITING Fukuoka 812-8582 Japan Details
Okayama University Hospital ( Site 0007) RECRUITING Okayama 700-8558 Japan Details
Nippon Medical School Hospital ( Site 0003) RECRUITING Tokyo 113-8603 Japan Details
Wakayama Medical University Hospital ( Site 0006) RECRUITING Wakayama 641-8510 Japan Details
Chonnam National University Hwasun Hospital-Pulmonology ( Site 0061) RECRUITING Hwasun Jeonranamdo 58128 Korea, Republic of Details
Pusan National University Yangsan Hospital ( Site 0060) RECRUITING Busan Kyongsangnam-do 50612 Korea, Republic of Details
Chungnam national university hospital-Department of Internal Medicine ( Site 0063) RECRUITING Daejeon Taejon-Kwangyokshi 35015 Korea, Republic of Details
Asan Medical Center ( Site 0064) RECRUITING Seoul 05505 Korea, Republic of Details
Korea University Guro Hospital-Internal Medicine ( Site 0062) RECRUITING Seoul Korea, Republic of Details
Daugavpils Regional Hospital-Oncology Department ( Site 0194) RECRUITING Daugavpils Daugavpils Novads 5417 Latvia Details
Liepjas reionl slimnca ( Site 0191) RECRUITING Liepaja LV-3414 Latvia Details
Pauls Stradins Clinical Univeristy Hospital-Chemotherapy department ( Site 0192) RECRUITING Riga LV1002 Latvia Details
RIGA EAST UNIVERSITY HOSPITAL ,Oncology Centre of Latvia-Out-patient and Day patient facility of Ch RECRUITING Riga LV1079 Latvia Details
Hospital of Lithuanian University of Health Sciences Kauno klinikos-Pulmonology ( Site 0692) RECRUITING Kaunas Kauno Apskritis 50161 Lithuania Details
National Cancer Institute-Department of Thoracic Surgery and Oncology ( Site 0691) RECRUITING Vilnius Vilniaus Miestas 08660 Lithuania Details
Hospital Raja Perempuan Zainab II-Medical Department ( Site 0035) RECRUITING Kota Bharu Kelantan 15586 Malaysia Details
Hospital Pulau Pinang-Oncology, radiotherapy and palliat ( Site 0034) RECRUITING George Town Pulau Pinang 10450 Malaysia Details
Beacon Hospital Sdn Bhd ( Site 0033) RECRUITING Petaling Jaya Selangor 46050 Malaysia Details
Clinica Vallesur - AUNA ( Site 0360) RECRUITING Arequipa Ariqipa 04001 Peru Details
Instituto Regional de Enfermedades Neoplasicas del Centro (IREN CENTRO) ( Site 0362) RECRUITING Concepcion Junin 12125 Peru Details
Centro de investigacion Clínica Trujillo ( Site 0358) RECRUITING Trujillo La Libertad 13001 Peru Details
Detecta Clínica ( Site 0364) RECRUITING Surquillo Lima 15038 Peru Details
Clínica Internacional - Sede San Borja ( Site 0356) RECRUITING Lima 15036 Peru Details
Hospital Cayetano Heredia ( Site 0361) RECRUITING Lima 15102 Peru Details
Metro Davao Medical and Research Center ( Site 0047) RECRUITING Davao City Davao Del Sur 8000 Philippines Details
ST. LUKE'S MEDICAL CENTER ( Site 0046) RECRUITING Quezon City National Capital Region 1102 Philippines Details
Cebu Doctors University Hospital ( Site 0045) RECRUITING Cebu 6000 Philippines Details
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 0208) RECRUITING Bydgoszcz Kujawsko-pomorskie 85-796 Poland Details
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 0201) RECRUITING Siedlce Mazowieckie 08-110 Poland Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier RECRUITING Warszawa Mazowieckie 02-781 Poland Details
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 0203) RECRUITING Przemysl Podkarpackie 37-700 Poland Details
Szpital Specjalistyczny w Prabutach Spolka z o.o. ( Site 0202) RECRUITING Prabuty Pomorskie 82-550 Poland Details
Szpital Rejonowy im. dr. J. Rostka w Raciborzu ( Site 0207) RECRUITING Racibórz Slaskie 47-400 Poland Details
Med-Polonia Sp. z o. o. ( Site 0204) RECRUITING Poznan Wielkopolskie 60-693 Poland Details
Gral Medical SRL-Medical Oncology ( Site 0220) RECRUITING București Bucuresti 031422 Romania Details
Cardiomed SRL Cluj-Napoca ( Site 0217) RECRUITING Cluj-Napoca Cluj 400015 Romania Details
Amethyst Radiotherapy Center-Oncologie Medicala ( Site 0216) RECRUITING Florești Cluj 407280 Romania Details
Centrul de Oncologie "Sfântul Nectarie"-Medical Oncology ( Site 0215) RECRUITING Craiova Dolj 200542 Romania Details
Cabinet Medical Oncomed ( Site 0219) RECRUITING Timișoara Timis 300239 Romania Details
Institutul Oncologic-Oncologie Medicala ( Site 0218) RECRUITING Cluj 400015 Romania Details
Chung Shan Medical University Hospital ( Site 0078) RECRUITING Taichung City Taichung 402 Taiwan Details
National Taiwan University Cancer Center (NTUCC) ( Site 0079) RECRUITING Taipei City Taipei 106 Taiwan Details
E-Da hospital ( Site 0075) RECRUITING Kaohsiung 82445 Taiwan Details
National Cheng Kung University Hospital-Clinical Trial Center ( Site 0076) RECRUITING Tainan 704 Taiwan Details
National Taiwan University Hospital-Internal Medicine ( Site 0080) RECRUITING Taipei 10002 Taiwan Details
Chang Gung Medical Foundation-Linkou Branch ( Site 0082) RECRUITING Taoyuan 333 Taiwan Details
Maharaj Nakorn Chiang Mai Hospital ( Site 0092) RECRUITING Muang Chiang Mai 50200 Thailand Details
Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 0097) RECRUITING Bangkok Krung Thep Maha Nakhon 10300 Thailand Details
Faculty of Medicine Siriraj Hospital ( Site 0090) RECRUITING Bangkok Krung Thep Maha Nakhon 10700 Thailand Details
Lampang Cancer Hospital ( Site 0098) RECRUITING Mueang Lampang Lampang 52000 Thailand Details
Songklanagarind hospital ( Site 0091) RECRUITING Hatyai Songkhla 90110 Thailand Details
Sunpasitthiprasong Hospital ( Site 0093) RECRUITING Ubon Ratchathani 34000 Thailand Details
Hacettepe Universite Hastaneleri-oncology hospital ( Site 0265) RECRUITING Ankara 06230 Turkey Details
Liv Hospital Ankara-Oncology ( Site 0274) RECRUITING Ankara 06680 Turkey Details
Ankara City Hospital-Medical Oncology ( Site 0268) RECRUITING Ankara 06800 Turkey Details
Trakya University-Medical Oncology ( Site 0270) RECRUITING Edirne 22030 Turkey Details
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 0267) RECRUITING Istanbul 34722 Turkey Details
VM Medical Park Pendik Hospital ( Site 0271) RECRUITING Istanbul 34899 Turkey Details
I.E.U. Medical Point Hastanesi-Oncology ( Site 0266) RECRUITING Izmir 35575 Turkey Details
Mersin Sehir Eğitim ve Araştırma Hastanesi ( Site 0275) RECRUITING Mersin 33240 Turkey Details
University College London Hospital ( Site 0305) RECRUITING London England NW1 2PG United Kingdom Details
Leicester Royal Infirmary-HOPE Clinical Trials Unit ( Site 0300) RECRUITING Leicester Leicestershire LE1 5WW United Kingdom Details
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 0302) RECRUITING London London, City Of EC1A 7BE United Kingdom Details
The Clatterbridge Cancer Centre ( Site 0303) RECRUITING Wirral CH63 4JY United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field