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| NCT ID | NCT05687266 |
| Title | Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations (AVANZAR) |
| Acronym | AVANZAR |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | POL | ITA | HUN | GRC | GBR | FRA | ESP | DEU | CAN | BRA | BGR | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85054 | United States | Details | |
| Research Site | Tucson | Arizona | 85704 | United States | Details | |
| Research Site | Hot Springs National Park | Arkansas | 71913 | United States | Details | |
| Research Site | Little Rock | Arkansas | 72205 | United States | Details | |
| Research Site | Springdale | Arkansas | 72762 | United States | Details | |
| Research Site | Fountain Valley | California | 92708 | United States | Details | |
| Research Site | Los Angeles | California | 90017 | United States | Details | |
| Research Site | Orange | California | 92868 | United States | Details | |
| Research Site | Boulder | Colorado | 80303 | United States | Details | |
| Research Site | Fort Myers | Florida | 33901 | United States | Details | |
| Research Site | Jacksonville | Florida | 32224 | United States | Details | |
| Research Site | Lakeland | Florida | 33812 | United States | Details | |
| Research Site | Saint Petersburg | Florida | 33705 | United States | Details | |
| Research Site | West Palm Beach | Florida | 33401 | United States | Details | |
| Research Site | Hinsdale | Illinois | 60521 | United States | Details | |
| Research Site | Fort Wayne | Indiana | 46845 | United States | Details | |
| Research Site | Bettendorf | Iowa | 52722 | United States | Details | |
| Research Site | Des Moines | Iowa | 50309 | United States | Details | |
| Research Site | Iowa City | Iowa | 52242 | United States | Details | |
| Research Site | Baton Rouge | Louisiana | 70808 | United States | Details | |
| Research Site | Covington | Louisiana | 70433 | United States | Details | |
| Research Site | Duluth | Minnesota | 55805 | United States | Details | |
| Research Site | Rochester | Minnesota | 55905 | United States | Details | |
| Research Site | Hannibal | Missouri | 63401 | United States | Details | |
| Research Site | Lincoln | Nebraska | 68506 | United States | Details | |
| Research Site | Lincoln | Nebraska | 68516 | United States | Details | |
| Research Site | Clifton Park | New York | 12065 | United States | Details | |
| Research Site | Asheville | North Carolina | 28806 | United States | Details | |
| Research Site | Canton | Ohio | 44710 | United States | Details | |
| Research Site | Columbus | Ohio | 43219 | United States | Details | |
| Research Site | Maumee | Ohio | 43537 | United States | Details | |
| Research Site | Tulsa | Oklahoma | 74134 | United States | Details | |
| Research Site | Portland | Oregon | 97239 | United States | Details | |
| Research Site | Salem | Oregon | 97301 | United States | Details | |
| Research Site | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Research Site | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| Research Site | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Research Site | York | Pennsylvania | 17403 | United States | Details | |
| Research Site | Watertown | South Dakota | 57201 | United States | Details | |
| Research Site | Memphis | Tennessee | 38120 | United States | Details | |
| Research Site | Dallas | Texas | 75246 | United States | Details | |
| Research Site | Fort Worth | Texas | 76104 | United States | Details | |
| Research Site | Houston | Texas | 77030 | United States | Details | |
| Research Site | Houston | Texas | 77090 | United States | Details | |
| Research Site | Irving | Texas | 75063 | United States | Details | |
| Research Site | Fairfax | Virginia | 22031 | United States | Details | |
| Research Site | Henrico | Virginia | 23229 | United States | Details | |
| Research Site | Norfolk | Virginia | 23502 | United States | Details | |
| Research Site | Renton | Washington | 98055 | United States | Details | |
| Research Site | Spokane | Washington | 99202 | United States | Details | |
| Research Site | Tacoma | Washington | 98405 | United States | Details | |
| Research Site | Appleton | Wisconsin | 54911 | United States | Details | |
| Research Site | La Crosse | Wisconsin | 54601 | United States | Details | |
| Research Site | Graz | 8036 | Austria | Details | ||
| Research Site | Rankweil | 6830 | Austria | Details | ||
| Research Site | Wien | 1090 | Austria | Details | ||
| Research Site | Wien | 1210 | Austria | Details | ||
| Research Site | Blumenau | 89010-340 | Brazil | Details | ||
| Research Site | Florianópolis | 88034-000 | Brazil | Details | ||
| Research Site | Fortaleza | 60336-045 | Brazil | Details | ||
| Research Site | Londrina | 86015-520 | Brazil | Details | ||
| Research Site | Porto Alegre | 90035-903 | Brazil | Details | ||
| Research Site | Sao Paulo | 01327-001 | Brazil | Details | ||
| Research Site | Sao Paulo | 01509-900 | Brazil | Details | ||
| Research Site | Sao Paulo | 09323-900 | Brazil | Details | ||
| Research Site | São Paulo | 01246-000 | Brazil | Details | ||
| Research Site | Taubaté | 12030-200 | Brazil | Details | ||
| Research Site | Vitoria | 29043-260 | Brazil | Details | ||
| Research Site | Sofia | 1113 | Bulgaria | Details | ||
| Research Site | Sofia | 1330 | Bulgaria | Details | ||
| Research Site | Varna | 9010 | Bulgaria | Details | ||
| Research Site | Saint John | New Brunswick | E2L 4L2 | Canada | Details | |
| Research Site | Brampton | Ontario | L6R 3J7 | Canada | Details | |
| Research Site | Kitchener | Ontario | N2G 1G3 | Canada | Details | |
| Research Site | Newmarket | Ontario | L3Y 2P9 | Canada | Details | |
| Research Site | Sudbury | Ontario | P3E 5J1 | Canada | Details | |
| Research Site | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| Research Site | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Research Site | Montreal | Quebec | H4J 1C5 | Canada | Details | |
| Research Site | St-Jerome | Quebec | J7Z 5T3 | Canada | Details | |
| Research Site | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details | |
| Research Site | Beijing | 100010 | China | Details | ||
| Research Site | Beijing | 100029 | China | Details | ||
| Research Site | Beijing | 100037 | China | Details | ||
| Research Site | Beijing | 100039 | China | Details | ||
| Research Site | Beijing | 100853 | China | Details | ||
| Research Site | Beijing | CN-100730 | China | Details | ||
| Research Site | Changsha | 410008 | China | Details | ||
| Research Site | Changsha | 410013 | China | Details | ||
| Research Site | Chengdu | 610041 | China | Details | ||
| Research Site | Chengdu | 610072 | China | Details | ||
| Research Site | Chongqing | 400037 | China | Details | ||
| Research Site | Guangzhou | 510000 | China | Details | ||
| Research Site | Guangzhou | 510100 | China | Details | ||
| Research Site | Hefei | 230601 | China | Details | ||
| Research Site | Jinan | 250021 | China | Details | ||
| Research Site | Kunming | 650101 | China | Details | ||
| Research Site | Lanzhou | 730000 | China | Details | ||
| Research Site | Liuzhou | 545006 | China | Details | ||
| Research Site | Shandong | China | Details | |||
| Research Site | Shanghai | 200030 | China | Details | ||
| Research Site | Shanghai | 200032 | China | Details | ||
| Research Site | Shanghai | 200080 | China | Details | ||
| Research Site | Shantou | 515041 | China | Details | ||
| Research Site | Shenyang | 110004 | China | Details | ||
| Research Site | Shenzhen | 517108 | China | Details | ||
| Research Site | Taiyuan | 030000 | China | Details | ||
| Research Site | Tianjin | 300060 | China | Details | ||
| Research Site | Wenzhou | 325000 | China | Details | ||
| Research Site | Wuhan | 430030 | China | Details | ||
| Research Site | Wuhan | 430060 | China | Details | ||
| Research Site | Xiamen | 361004 | China | Details | ||
| Research Site | Yangzhou | 225001 | China | Details | ||
| Research Site | Zhengzhou | 450052 | China | Details | ||
| Research Site | Brest | 29200 | France | Details | ||
| Research Site | Creteil | 94010 | France | Details | ||
| Research Site | Gleize | 69400 | France | Details | ||
| Research Site | Montpellier | 34070 | France | Details | ||
| Research Site | Nimes | 30029 | France | Details | ||
| Research Site | Paris CEDEX 14 | 75674 | France | Details | ||
| Research Site | Paris | 75018 | France | Details | ||
| Research Site | Rouen | 76031 | France | Details | ||
| Research Site | Saint-Quentin | 02321 | France | Details | ||
| Research Site | Strasbourg Cedex | 67091 | France | Details | ||
| Research Site | Toulon Cedex 9 | 83800 | France | Details | ||
| Research Site | Toulouse | 31059 | France | Details | ||
| Research Site | Tours | 37000 | France | Details | ||
| Research Site | Bad Berka | 99437 | Germany | Details | ||
| Research Site | Berlin | 14109 | Germany | Details | ||
| Research Site | Frankfurt A. Main | 60590 | Germany | Details | ||
| Research Site | Gauting | 82131 | Germany | Details | ||
| Research Site | Gütersloh | 33332 | Germany | Details | ||
| Research Site | Hamburg | 20251 | Germany | Details | ||
| Research Site | Kassel | 34125 | Germany | Details | ||
| Research Site | Kiel | 24116 | Germany | Details | ||
| Research Site | Koblenz | 56073 | Germany | Details | ||
| Research Site | Minden | 32429 | Germany | Details | ||
| Research Site | Rosenheim | 83022 | Germany | Details | ||
| Research Site | Velbert | 42551 | Germany | Details | ||
| Research Site | Würzburg | 97074 | Germany | Details | ||
| Research Site | Athens | 11526 | Greece | Details | ||
| Research Site | Athens | 11527 | Greece | Details | ||
| Research Site | Athens | 155 62 | Greece | Details | ||
| Research Site | Peiraias | 185 47 | Greece | Details | ||
| Research Site | Thessaloniki | 55236 | Greece | Details | ||
| Research Site | Thessaloniki | 57001 | Greece | Details | ||
| Research Site | Budapest | 1121 | Hungary | Details | ||
| Research Site | Budapest | 1122 | Hungary | Details | ||
| Research Site | Gyöngyös - Mátraháza | 3200 | Hungary | Details | ||
| Research Site | Kaposvár | 7400 | Hungary | Details | ||
| Research Site | Pécs | 7624 | Hungary | Details | ||
| Research Site | Szekszárd | 7100 | Hungary | Details | ||
| Research Site | Szolnok | 5000 | Hungary | Details | ||
| Research Site | Törökbálint | 2045 | Hungary | Details | ||
| Research Site | Calicut | 673601 | India | Details | ||
| Research Site | Delhi | 110029 | India | Details | ||
| Research Site | Delhi | 110085 | India | Details | ||
| Research Site | Jaipur | 302017 | India | Details | ||
| Research Site | Kolkata | 700160 | India | Details | ||
| Research Site | Madurai | 625107 | India | Details | ||
| Research Site | Puducherry | 605006 | India | Details | ||
| Research Site | Firenze | 50134 | Italy | Details | ||
| Research Site | Lecco | 23900 | Italy | Details | ||
| Research Site | Messina | 98158 | Italy | Details | ||
| Research Site | Napoli | 80131 | Italy | Details | ||
| Research Site | Orbassano | 10043 | Italy | Details | ||
| Research Site | Padova | 35128 | Italy | Details | ||
| Research Site | Parma | 43126 | Italy | Details | ||
| Research Site | Peschiera Del Garda | 37019 | Italy | Details | ||
| Research Site | Rozzano | 20089 | Italy | Details | ||
| Research Site | Bunkyo-ku | 113-8603 | Japan | Details | ||
| Research Site | Chuo-ku | 104-0045 | Japan | Details | ||
| Research Site | Hamamatsu-shi | 431-3192 | Japan | Details | ||
| Research Site | Hamamatsu-shi | 432-8580 | Japan | Details | ||
| Research Site | Hidaka-shi | 350-1298 | Japan | Details | ||
| Research Site | Hirosaki-shi | 036-8563 | Japan | Details | ||
| Research Site | Hiroshima-shi | 730-8518 | Japan | Details | ||
| Research Site | Kumamoto-shi | 860-8556 | Japan | Details | ||
| Research Site | Nagoya-shi | 464-8681 | Japan | Details | ||
| Research Site | Nagoya-shi | 466-8560 | Japan | Details | ||
| Research Site | Okayama-shi | 700-8558 | Japan | Details | ||
| Research Site | Osaka-shi | 545-8586 | Japan | Details | ||
| Research Site | Osakasayama-shi | 589-8511 | Japan | Details | ||
| Research Site | Sapporo-shi | 060-8638 | Japan | Details | ||
| Research Site | Sunto-gun | 411-8777 | Japan | Details | ||
| Research Site | Wakayama-shi | 641-8510 | Japan | Details | ||
| Research Site | Yokohama-shi | 221-0855 | Japan | Details | ||
| Research Site | Yokohama-shi | 241-8515 | Japan | Details | ||
| Research Site | Busan | 48108 | Korea, Republic of | Details | ||
| Research Site | Cheongju-si | 28644 | Korea, Republic of | Details | ||
| Research Site | Jinju-si | 52727 | Korea, Republic of | Details | ||
| Research Site | Seoul | 03080 | Korea, Republic of | Details | ||
| Research Site | Seoul | 03722 | Korea, Republic of | Details | ||
| Research Site | Seoul | 05505 | Korea, Republic of | Details | ||
| Research Site | Seoul | 06351 | Korea, Republic of | Details | ||
| Research Site | Seoul | 07061 | Korea, Republic of | Details | ||
| Research Site | Suwon-si | 16499 | Korea, Republic of | Details | ||
| Research Site | Suwon | 16247 | Korea, Republic of | Details | ||
| Research Site | Cdmx | 03810 | Mexico | Details | ||
| Research Site | Del. Cuauhtemoc | 06700 | Mexico | Details | ||
| Research Site | Mexico | 14080 | Mexico | Details | ||
| Research Site | San Luis Potosí | 78209 | Mexico | Details | ||
| Research Site | Arequipa | 04002 | Peru | Details | ||
| Research Site | Concepción | 12125 | Peru | Details | ||
| Research Site | Lima | 15036 | Peru | Details | ||
| Research Site | Lima | 34 | Peru | Details | ||
| Research Site | Lima | LIMA 27 | Peru | Details | ||
| Research Site | Lima | LIMA 29 | Peru | Details | ||
| Research Site | Bydgoszcz | 85-796 | Poland | Details | ||
| Research Site | Bystra | 43-360 | Poland | Details | ||
| Research Site | Grudziądz | 86-300 | Poland | Details | ||
| Research Site | Kielce | 25-734 | Poland | Details | ||
| Research Site | Koszalin | 75-581 | Poland | Details | ||
| Research Site | Olsztyn | 10-357 | Poland | Details | ||
| Research Site | Poznań | 60-569 | Poland | Details | ||
| Research Site | Przemysl | 37-700 | Poland | Details | ||
| Research Site | Racibórz | 47-400 | Poland | Details | ||
| Research Site | Radom | 26-600 | Poland | Details | ||
| Research Site | Siedlce | 08-110 | Poland | Details | ||
| Research Site | Las Palmas de Gran Canaria | 35016 | Spain | Details | ||
| Research Site | Lugo | 27003 | Spain | Details | ||
| Research Site | Madrid | 28041 | Spain | Details | ||
| Research Site | Santander | 39008 | Spain | Details | ||
| Research Site | Sevilla | 41013 | Spain | Details | ||
| Research Site | Valencia | 46010 | Spain | Details | ||
| Research Site | Zaragoza | 50009 | Spain | Details | ||
| Research Site | Gävle | 801 88 | Sweden | Details | ||
| Research Site | Linköping | 581 85 | Sweden | Details | ||
| Research Site | Lund | 221 85 | Sweden | Details | ||
| Research Site | Stockholm | 17176 | Sweden | Details | ||
| Research Site | Uppsala | 751 85 | Sweden | Details | ||
| Research Site | Hsinchu | 300 | Taiwan | Details | ||
| Research Site | Taichung | 40705 | Taiwan | Details | ||
| Research Site | Tainan City | 73657 | Taiwan | Details | ||
| Research Site | Taipei City | 11217 | Taiwan | Details | ||
| Research Site | Taipei | 235 | Taiwan | Details | ||
| Research Site | Taoyuan City | 333 | Taiwan | Details | ||
| Research Site | Adana | 01060 | Turkey | Details | ||
| Research Site | Ankara | 06800 | Turkey | Details | ||
| Research Site | Edirne | 22030 | Turkey | Details | ||
| Research Site | Istanbul | 34098 | Turkey | Details | ||
| Research Site | Izmir | 35110 | Turkey | Details | ||
| Research Site | Aberdeen | AB25 2ZN | United Kingdom | Details | ||
| Research Site | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Research Site | Cardiff | CF14 2TL | United Kingdom | Details | ||
| Research Site | Cheltenham | GL53 7AN | United Kingdom | Details | ||
| Research Site | Edinburgh | EH4 2XU | United Kingdom | Details | ||
| Research Site | London | SE1 9RT | United Kingdom | Details | ||
| Research Site | London | W6 8RF | United Kingdom | Details | ||
| Research Site | Manchester | M20 4BX | United Kingdom | Details | ||
| Research Site | Middlesborough | TS4 3BW | United Kingdom | Details | ||
| Research Site | Newcastle-Upon-Tyne | NE7 7DN | United Kingdom | Details | ||
| Research Site | Taunton | TA1 5DA | United Kingdom | Details | ||
| Research Site | Hanoi | 100000 | Vietnam | Details | ||
| Research Site | Ho Chi Minh city | 700000 | Vietnam | Details | ||
| Research Site | Ho Chi Minh | 700000 | Vietnam | Details |