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| NCT ID | NCT05696626 |
| Title | Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation (ELAINEIII) |
| Acronym | ELAINEIII |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Sermonix Pharmaceuticals Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | ROU | POL | ITA | ISR | GBR | FRA | ESP | DEU | CZE | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic - Phoenix | RECRUITING | Phoenix | Arizona | 85054 | United States | Details |
| University of Arizona - Cancer Center | RECRUITING | Tucson | Arizona | 85719 | United States | Details |
| California Research Institute | RECRUITING | Los Angeles | California | 90027 | United States | Details |
| Providence Medical Foundation - Santa Rosa, CA | RECRUITING | Santa Rosa | California | 95403 | United States | Details |
| Boca Raton Regional Hospital | RECRUITING | Boca Raton | Florida | 33486 | United States | Details |
| Mayo Clinic - Jacksonville | RECRUITING | Jacksonville | Florida | 32224 | United States | Details |
| Miami Cancer Institute | RECRUITING | Miami | Florida | 33143 | United States | Details |
| Miami Cancer Institute Plantation | RECRUITING | Plantation | Florida | 33324 | United States | Details |
| Emory University School of Medicine | RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Norton Cancer Institute | RECRUITING | Louisville | Kentucky | 40202 | United States | Details |
| Hematology Oncology Clinic | RECRUITING | Baton Rouge | Louisiana | 70809 | United States | Details |
| Johns Hopkins Kimmel Cancer Center | RECRUITING | Baltimore | Maryland | 21231 | United States | Details |
| Massachusetts General Hospital | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02115 | United States | Details |
| Beth Israel Deaconess Medical Center | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Cancer and Hematology Centers of Western Michigan | RECRUITING | Grand Rapids | Michigan | 49503 | United States | Details |
| Allina Health System DBA Virginia Piper Cancer Institute | NOT_YET_RECRUITING | Minneapolis | Minnesota | 55407 | United States | Details |
| Mayo Clinic - Rochester | RECRUITING | Rochester | Minnesota | 55905 | United States | Details |
| Saint Luke's Cancer Institute | RECRUITING | Kansas City | Missouri | 64111 | United States | Details |
| Washington University School of Medicine | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| University of Nebraska Medical Center | SUSPENDED | Omaha | Nebraska | 68198 | United States | Details |
| Renown Regional Medical Centre | NOT_YET_RECRUITING | Reno | Nevada | 89502 | United States | Details |
| New Jersey Cancer Care, PA | NOT_YET_RECRUITING | Belleville | New Jersey | 07109 | United States | Details |
| Icahn School of Medicine at Mount Sinai | RECRUITING | New York | New York | 10029 | United States | Details |
| David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center | RECRUITING | New York | New York | 10065 | United States | Details |
| Duke University Medical Center | RECRUITING | Durham | North Carolina | 27705 | United States | Details |
| Altru Health Systems | RECRUITING | Grand Forks | North Dakota | 58201 | United States | Details |
| The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solovev Research Institute (OSUCCC - James) | RECRUITING | Columbus | Ohio | 42112 | United States | Details |
| Oklahoma University Health Sciences Center | RECRUITING | Oklahoma City | Oklahoma | 73104 | United States | Details |
| University of Pittsburgh Medical Center | RECRUITING | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| Lyndon B. Johnson Hospital | RECRUITING | Houston | Texas | 77026 | United States | Details |
| Baylor College of Medicine | RECRUITING | Houston | Texas | 77030 | United States | Details |
| MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Harris Health System - Smith Clinic | RECRUITING | Houston | Texas | 77054 | United States | Details |
| University of Vermont Medical Center | NOT_YET_RECRUITING | Burlington | Vermont | 05401 | United States | Details |
| Blacktown Hospital | RECRUITING | Blacktown | Australia | Details | ||
| Concord Repatriation General Hospital | NOT_YET_RECRUITING | Concord | Australia | Details | ||
| Mater Misericordiae Ltd, South Brisbane | NOT_YET_RECRUITING | South Brisbane | Australia | Details | ||
| Cliniques Universitaires Saint-Luc | NOT_YET_RECRUITING | Brussels | Belgium | Details | ||
| Antwerp University Hospital (UZA) | NOT_YET_RECRUITING | Edegem | Belgium | Details | ||
| Universitaire Ziekenhuizen Leuven | NOT_YET_RECRUITING | Leuven | Belgium | Details | ||
| Clinique CHC MontLégia | NOT_YET_RECRUITING | Liège | Belgium | Details | ||
| CHU UCL Namur - Site De Sainte-Elisabeth | NOT_YET_RECRUITING | Namur | Belgium | Details | ||
| The Ottawa General Hospital | RECRUITING | Ottawa | Ontario | Canada | Details | |
| Sunnybrook Health Sciences Centre -Bayview Campus | RECRUITING | Toronto | Ontario | Canada | Details | |
| Hospital Maisonneuve-Rosemont | NOT_YET_RECRUITING | Montréal | Quebec | Canada | Details | |
| Lady Davis Institute for Medical Research Jewish General Hospital | NOT_YET_RECRUITING | Montréal | Quebec | Canada | Details | |
| Masarykuv onkologicky ustav | SUSPENDED | Brno | Czechia | Details | ||
| Fakultni nemocnice Hradec Kralove | SUSPENDED | Hradec Králové | Czechia | Details | ||
| Fakultni nemocnice Olomouc - Oncology clinic | SUSPENDED | Olomouc | Czechia | Details | ||
| Fakultní nemocnice v Motole | SUSPENDED | Praha 5 | Czechia | Details | ||
| Service d'Oncologie Medicale - CHRU Besancon | NOT_YET_RECRUITING | Besançon | France | Details | ||
| Institut Bergonie | NOT_YET_RECRUITING | Bordeaux | France | Details | ||
| Centre Francois Baclesse | NOT_YET_RECRUITING | CAEN Cedex 05 | France | Details | ||
| Centre Oscar Lambret | NOT_YET_RECRUITING | Lille | France | Details | ||
| Centre Leon Berard | RECRUITING | Lyon | France | Details | ||
| Institut Paoli-Calmettes | RECRUITING | Marseille | France | Details | ||
| CHU Poitiers - Pole Regional de Cancerologie de Poitiers (PRC) | NOT_YET_RECRUITING | Poitiers | France | Details | ||
| Centre Henri Becquerel | NOT_YET_RECRUITING | Rouen | France | Details | ||
| Institut de cancerologie Strasbourg Europe (ICANS) | NOT_YET_RECRUITING | Strasbourg | France | Details | ||
| Institut Claudius Regaud | RECRUITING | Toulouse | France | Details | ||
| Universitaetsklinikum Carl Gustav Carus Dresden | NOT_YET_RECRUITING | Dresden | Germany | Details | ||
| Universitaetsklinikum Ulm | NOT_YET_RECRUITING | Ulm | Germany | Details | ||
| Rambam Health Care Campus | RECRUITING | Haifa | Israel | Details | ||
| Hadassah Ein-Karem Medical Center | RECRUITING | Jerusalem | Israel | Details | ||
| Shaare Zedek Medical Center | RECRUITING | Jerusalem | Israel | Details | ||
| Rabin MC | RECRUITING | Petach Tikva | Israel | Details | ||
| Kaplan Medical Center | NOT_YET_RECRUITING | Reẖovot | Israel | Details | ||
| Tel Aviv Sourasky Medical Center | RECRUITING | Tel Aviv | Israel | Details | ||
| Sheba Medical Center | RECRUITING | Tel HaShomer | Israel | Details | ||
| Centro Riferimento Oncologico - Aviano | NOT_YET_RECRUITING | Aviano | Italy | Details | ||
| IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST S.r.l. | RECRUITING | Meldola | Italy | Details | ||
| Istituto Europeo di Oncologia | NOT_YET_RECRUITING | Milano | Italy | Details | ||
| Humanitas Istituto Clinico Catanese | NOT_YET_RECRUITING | Misterbianco | Italy | Details | ||
| Azienda Ospedaliero-Universitaria di Modena | NOT_YET_RECRUITING | Modena | Italy | Details | ||
| Istituto Nazionale Tumori IRCCS Fondazione G. Pascale | RECRUITING | Napoli | Italy | Details | ||
| Azienda Ospedaliero Universitaria di Parma | NOT_YET_RECRUITING | Parma | Italy | Details | ||
| Fondazione IRCCS Policlinico San Matteo | NOT_YET_RECRUITING | Pavia | Italy | Details | ||
| Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore | RECRUITING | Roma | Italy | Details | ||
| Azienda Ospedaliera Universitaria Integrata Verona-Ospedale Borgo Trento | NOT_YET_RECRUITING | Verona | Italy | Details | ||
| National Cancer Center | NOT_YET_RECRUITING | Gyeonggi-do | Korea, Republic of | Details | ||
| Chonnam National University Hwasun Hospital | NOT_YET_RECRUITING | Hwasun | 58128 | Korea, Republic of | Details | |
| Asan Medical Center | NOT_YET_RECRUITING | Seoul | Korea, Republic of | Details | ||
| Korea University Anam Hospital | NOT_YET_RECRUITING | Seoul | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | NOT_YET_RECRUITING | Seoul | Korea, Republic of | Details | ||
| KO - MED Centra Kliniczne Sp. z o.o., Wojewodzki Szpital Specjalistyczny w Bialej Podlaskiej | NOT_YET_RECRUITING | Biała Podlaska | Poland | Details | ||
| Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii | NOT_YET_RECRUITING | Gdańsk | Poland | Details | ||
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Oddzial w Gliwicach, I Klinika Radioterapii i Chemioterapii | NOT_YET_RECRUITING | Gliwice | Poland | Details | ||
| Swietokrzyskie Centrum Onkologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej, Klinika Onkologii Klinicznej | NOT_YET_RECRUITING | Kielce | Poland | Details | ||
| Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie - Oddzial Onkologii Klinicznej z Pododdzialem Dziennym | NOT_YET_RECRUITING | Krakow | Poland | Details | ||
| SP ZOZ Szpital Uniwersytecki w Krakowie, Oddzial Onkologii Klinicznej | NOT_YET_RECRUITING | Kraków | Poland | Details | ||
| NeuroMed | NOT_YET_RECRUITING | Lublin | Poland | Details | ||
| Wielkopolskie Centrum Onkologii (WCO) / The Greater Poland Cancer Center | NOT_YET_RECRUITING | Poznań | Poland | Details | ||
| Mazowiecki Szpital Onkologiczny | NOT_YET_RECRUITING | Wieliszew | Poland | Details | ||
| Instytut Centrum Zdrowia Matki Polki - Klinika Onkologii | RECRUITING | Łódź | Poland | Details | ||
| Centrul Medical Focus | NOT_YET_RECRUITING | Bucharest | Romania | Details | ||
| Filantropia Clinical Hospital | NOT_YET_RECRUITING | Bucharest | Romania | Details | ||
| Radiotherapy Center Cluj | NOT_YET_RECRUITING | Cluj-Napoca | Romania | Details | ||
| Onco Clinic Consult SA | NOT_YET_RECRUITING | Craiova | Romania | Details | ||
| Oncology Center Sfantul Nectarie | NOT_YET_RECRUITING | Craiova | Romania | Details | ||
| Gral Medical SRL | NOT_YET_RECRUITING | Piteşti | Romania | Details | ||
| OncoMed Oncology Center | NOT_YET_RECRUITING | Timişoara | Romania | Details | ||
| National Cancer Centre Singapore | NOT_YET_RECRUITING | Singapore | 168583 | Singapore | Details | |
| Curie Oncology | NOT_YET_RECRUITING | Singapore | 329563 | Singapore | Details | |
| Hospital Clinic Barcelona | RECRUITING | Barcelona | Spain | Details | ||
| Hospital Universitario Vall d'Hebron | NOT_YET_RECRUITING | Barcelona | Spain | Details | ||
| Hospital Universitario Reina Sofia | RECRUITING | Córdoba | Spain | Details | ||
| Clinica Universidad de Navarra - Madrid | RECRUITING | Madrid | Spain | Details | ||
| Hospital General Universitario Gregorio Maranon | RECRUITING | Madrid | Spain | Details | ||
| Hospital Universitario 12 de Octubre | RECRUITING | Madrid | Spain | Details | ||
| Hospital Universitario de La Princesa | RECRUITING | Madrid | Spain | Details | ||
| Hospital Regional Universitario de Malaga | RECRUITING | Málaga | Spain | Details | ||
| Clinica Universidad de Navarra - Pamplona | RECRUITING | Pamplona | Spain | Details | ||
| Instituto Valenciano de Oncologia | RECRUITING | Valencia | Spain | Details | ||
| Changhua Christian Hospital (CCH) | NOT_YET_RECRUITING | Changhua | Taiwan | Details | ||
| Kaohsiung Medical University Chung-Ho Memorial Hospital (KMUH) | NOT_YET_RECRUITING | Kaohsiung | Taiwan | Details | ||
| National Cheng Kung University Hospital | NOT_YET_RECRUITING | Tainan | Taiwan | Details | ||
| Tri-Service General Hospital | NOT_YET_RECRUITING | Taipei City | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center | NOT_YET_RECRUITING | Taipei | Taiwan | Details | ||
| National Taiwan University Hospital | NOT_YET_RECRUITING | Taipei | Taiwan | Details | ||
| Linkou Chang Gung Memorial Hospital (CGMHLK) | NOT_YET_RECRUITING | Taoyuan City | Taiwan | Details | ||
| Trakya University Medical Faculty | SUSPENDED | Merkez | Edirne | Turkey | Details | |
| Kocaeli University Faculty of Medicine | SUSPENDED | İzmit | Kocaeli | Turkey | Details | |
| Ankara University Medical Faculty Medical Oncology Department | SUSPENDED | Ankara | Turkey | Details | ||
| Uludag University Medical Faculty | SUSPENDED | Bursa | Turkey | Details | ||
| Liv Hospital Ankara | SUSPENDED | Cankaya | Turkey | Details | ||
| Goztepe Prof. Dr. Suleyman Yalcin City Hospital | SUSPENDED | Istanbul | Turkey | Details | ||
| Medical Point Izmir Hospital | SUSPENDED | İzmir | Turkey | Details | ||
| Suat Seren Training and Research Hospital | SUSPENDED | İzmir | Turkey | Details | ||
| West Middlesex University Hospital | NOT_YET_RECRUITING | Isleworth | United Kingdom | Details | ||
| Leeds Teaching Hospitals NHS Trust | NOT_YET_RECRUITING | Leeds | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | NOT_YET_RECRUITING | Manchester | United Kingdom | Details | ||
| Nottingham City Hospital | NOT_YET_RECRUITING | Nottingham | United Kingdom | Details | ||
| Lancashire Teaching Hospitals | NOT_YET_RECRUITING | Preston | United Kingdom | Details |