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| NCT ID | NCT05789082 |
| Title | A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation (Krascendo 170) |
| Acronym | Krascendo 170 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | POL | NLD | ITA | ISR | GBR | ESP | CHE | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCSD Moores Cancer Center | RECRUITING | La Jolla | California | 92093 | United States | Details |
| Yale Cancer Center | RECRUITING | New Haven | Connecticut | 06520 | United States | Details |
| NYU Langone Hospital - Long Island | RECRUITING | Mineola | New York | 11501 | United States | Details |
| NYU Cancer Center; NYU Cancer Institute | RECRUITING | New York | New York | 10016 | United States | Details |
| MD Anderson Cancer Center; Oncology | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Hospital Britanico; Oncologia | RECRUITING | Buenos Aires | C1280AEB | Argentina | Details | |
| Clinica Adventista Belgrano; Oncology | RECRUITING | Ciudad Autonoma Buenos Aires | C1430EGF | Argentina | Details | |
| Centro Oncologico Riojano Integral (CORI) | RECRUITING | La Rioja | F5300COE | Argentina | Details | |
| Concord Repatriation General Hospital; Concord Cancer Centre | RECRUITING | Concord | New South Wales | 2139 | Australia | Details |
| Peter MacCallum Cancer Centre; Medical Oncology | RECRUITING | Melbourne | Victoria | 3000 | Australia | Details |
| Alfred Health | RECRUITING | Melbourne | Victoria | 3004 | Australia | Details |
| Cliniques Universitaires St-Luc | RECRUITING | Bruxelles | 1200 | Belgium | Details | |
| Jessa Zkh (Campus Virga Jesse) | RECRUITING | Hasselt | 3500 | Belgium | Details | |
| Clinique Ste-Elisabeth | RECRUITING | Namur | 5000 | Belgium | Details | |
| AZ Delta (Campus Rumbeke) | RECRUITING | Roeselare | 8800 | Belgium | Details | |
| Crio - Centro Regional Integrado de Oncologia | WITHDRAWN | Fortaleza | CE | 60336-232 | Brazil | Details |
| Hospital Nossa Senhora da Conceicao | WITHDRAWN | Porto Alegre | RS | 90040-373 | Brazil | Details |
| Hospital de Cancer de Barretos | RECRUITING | Barretos | SP | 14784-400 | Brazil | Details |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | RECRUITING | Sao Paulo | SP | 01246-000 | Brazil | Details |
| Princess Margaret Cancer Center | ACTIVE_NOT_RECRUITING | Toronto | Ontario | M5G 1Z5 | Canada | Details |
| Jewish General Hospital | ACTIVE_NOT_RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Hunan Cancer Hospital | ACTIVE_NOT_RECRUITING | Changsha CITY | 410013 | China | Details | |
| Harbin Medical University Cancer Hospital | ACTIVE_NOT_RECRUITING | Harbin | 150081 | China | Details | |
| Shanghai Pulmonary Hospital | ACTIVE_NOT_RECRUITING | Shanghai | 200433 | China | Details | |
| Rambam Medical Center; Oncology | RECRUITING | Haifa | 3109601 | Israel | Details | |
| Rabin MC; Davidof Center - Oncology Institute | RECRUITING | Petach Tikva | 4941492 | Israel | Details | |
| Tel Aviv Sourasky Medical Ctr; Oncology | RECRUITING | Tel Aviv | 6423906 | Israel | Details | |
| Istituto Nazionale Tumori Fondazione G. Pascale | RECRUITING | Napoli | Campania | 80131 | Italy | Details |
| Policlinico Universitario Agostino Gemelli IRCCS; UOS Fase 1 | ACTIVE_NOT_RECRUITING | Roma | Lazio | 00168 | Italy | Details |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1 | RECRUITING | Milano | Lombardia | 20133 | Italy | Details |
| A.O. UNIVERSITARIA S. LUIGI GONZAGA; Oncologia Medica | RECRUITING | Orbassano | Piemonte | 10043 | Italy | Details |
| Pusan National University Hospital | RECRUITING | Busan | 602-739 | Korea, Republic of | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Asan Medical Center | RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Korea University Guro Hospital | RECRUITING | Seoul | 08308 | Korea, Republic of | Details | |
| NKI The Netherlands Cancer Institute | ACTIVE_NOT_RECRUITING | Amsterdam | 1066 CX | Netherlands | Details | |
| UMC St Radboud | RECRUITING | Nijmegen | 6525 GA | Netherlands | Details | |
| Uniwersyteckie Centrum Kliniczne; Osrodek Badan Wczesnych Faz | RECRUITING | Gda?sk | 80-214 | Poland | Details | |
| Krakowski Szpital Specjalistyczny im sw. Jana Paw?a II; Oddzia? Onkologiczny | RECRUITING | Kraków | 31-202 | Poland | Details | |
| Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie; Oddzial onkologii z pododdzialem chemioterapii | ACTIVE_NOT_RECRUITING | Olsztyn | 10-357 | Poland | Details | |
| ICO Badalona-H.U. Germans Trias i Pujol | RECRUITING | Badalona | Barcelona | 08916 | Spain | Details |
| NEXT Oncology-Hospital Quironsalud Madrid | WITHDRAWN | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details |
| Vall d?Hebron Institute of Oncology (VHIO), Barcelona | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital General Universitario Gregorio Marañon; Servicio de Oncologia | RECRUITING | Madrid | 28009 | Spain | Details | |
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | RECRUITING | Madrid | 28041 | Spain | Details | |
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | ACTIVE_NOT_RECRUITING | Sevilla | 41013 | Spain | Details | |
| Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia | RECRUITING | Valencia | 46010 | Spain | Details | |
| Sahlgrenska University Hospital; Sahlgrenska Clinical Trial unit / Department of Oncology | RECRUITING | Göteborg | 413 45 | Sweden | Details | |
| Universitätsspital Basel; Oncology - Klinische Forschung | ACTIVE_NOT_RECRUITING | Basel | 4031 | Switzerland | Details | |
| Inselspital Bern; Universitätsklinik für Medizinische Onkologie, Klinische Forschungseinheit | RECRUITING | Bern | 3010 | Switzerland | Details | |
| National Cheng Kung University Hospital; Internal Medicine | RECRUITING | North Dist. | 70403 | Taiwan | Details | |
| Taichung Veterans General Hospital; Dept of Internal Medicine | RECRUITING | Taichung | 407 | Taiwan | Details | |
| National Taiwan Uni Hospital; Internal Medicine | RECRUITING | Taipei | 100 | Taiwan | Details | |
| Chang Gung Medical Foundation - Linkou; Chest Dept | ACTIVE_NOT_RECRUITING | Taoyuan | 333 | Taiwan | Details | |
| Adana City Hospital, Medical Oncology | WITHDRAWN | Adana | 01060 | Turkey | Details | |
| Ankara Bilkent City Hospital | WITHDRAWN | Ankara | 06490 | Turkey | Details | |
| Koc University Hospital; Oncology | WITHDRAWN | Istanbul | Turkey | Details | ||
| Beatson West of Scotland Cancer Centre | RECRUITING | Glasgow | G12 0YN | United Kingdom | Details | |
| Barts & London School of Med; Medical Oncology | RECRUITING | London | EC1A 7BE | United Kingdom | Details |