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| NCT ID | NCT05845814 |
| Title | A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | ISR | GBR | FRA | ESP | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Moores Cancer Center ( Site 3028) | La Jolla | California | 92093 | United States | Details | |
| University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 3045) | Orange | California | 92868 | United States | Details | |
| Anschutz Cancer Pavilion ( Site 3017) | Aurora | Colorado | 80045 | United States | Details | |
| Emory University School of Medicine ( Site 3043) | Atlanta | Georgia | 30322 | United States | Details | |
| Indiana University Melvin and Bren Simon Cancer Center ( Site 3011) | Indianapolis | Indiana | 46202 | United States | Details | |
| Washington University School of Medicine ( Site 3038) | Saint Louis | Missouri | 63110 | United States | Details | |
| Icahn School of Medicine at Mount Sinai ( Site 3018) | New York | New York | 10029 | United States | Details | |
| Memorial Sloan Kettering Cancer Center ( Site 3031) | New York | New York | 10065 | United States | Details | |
| Cleveland Clinic-Taussig Cancer Center ( Site 3036) | Cleveland | Ohio | 44195 | United States | Details | |
| UPMC Hillman Cancer Center ( Site 3014) | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Huntsman Cancer Institute-HCI Clinical Trials Office ( Site 3041) | Salt Lake City | Utah | 84112 | United States | Details | |
| Royal Brisbane and Women's Hospital-Medical Oncology Clinical Trials Unit, Cancer Care Services ( Si | Brisbane | Queensland | 4029 | Australia | Details | |
| Austin Health-Cancer Clinical Trials Centre ( Site 3950) | Heidelberg | Victoria | 3084 | Australia | Details | |
| The Ottawa Hospital - General Campus-The Ottawa Hospital Cancer Centre ( Site 3105) | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Research Institute - Odette Cancer Centre ( Site 3108) | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Princess Margaret Cancer Centre ( Site 3106) | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| FALP-UIDO ( Site 3151) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
| Bradfordhill-Clinical Area ( Site 3155) | Santiago | Region M. De Santiago | 8420383 | Chile | Details | |
| ONCOCENTRO APYS-ACEREY ( Site 3158) | Viña del Mar | Valparaiso | 2520598 | Chile | Details | |
| Bradford Hill Norte ( Site 3152) | Antofagasta | 1240000 | Chile | Details | ||
| CHU de Bordeaux Hop St ANDRE ( Site 3607) | Bordeaux | Aquitaine | 33075 | France | Details | |
| Centre Georges François Leclerc-Centre de recherche clinique ( Site 3608) | Dijon | Cote-d Or | 21079 | France | Details | |
| Oncopole Claudius Regaud ( Site 3610) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Hôpital Européen Georges Pompidou ( Site 3605) | Paris | Ile-de-France | 75015 | France | Details | |
| centre hospitalier lyon sud ( Site 3606) | Pierre-Bénite | Rhone | 69310 | France | Details | |
| Rambam Health Care Campus-Oncology Division ( Site 3501) | Haifa | 3109601 | Israel | Details | ||
| Rabin Medical Center-Oncology ( Site 3504) | Petah Tikva | 4941492 | Israel | Details | ||
| Sheba Medical Center-ONCOLOGY ( Site 3503) | Ramat Gan | 5265601 | Israel | Details | ||
| Ospedale San Raffaele-Oncologia Medica ( Site 3403) | Milano | Lombardia | 20132 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 3405) | Milan | Lombardia | 20133 | Italy | Details | |
| Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 3406) | Napoli | 80131 | Italy | Details | ||
| Severance Hospital, Yonsei University Health System-Medical oncology ( Site 3903) | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center-Department of Oncology ( Site 3901) | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center ( Site 3902) | Seoul | 06351 | Korea, Republic of | Details | ||
| Maastricht UMC+ ( Site 3304) | Maastricht | Limburg | 6229 HX | Netherlands | Details | |
| Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)-medical oncology ( Site 3302) | Amsterdam | Noord-Holland | 1066 CX | Netherlands | Details | |
| Erasmus Medisch Centrum-Medical Oncology ( Site 3303) | Rotterdam | Zuid-Holland | 3015 GD | Netherlands | Details | |
| Hospital Universitari Vall d'Hebron ( Site 3767) | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinico San Carlos ( Site 3765) | Madrid | 28040 | Spain | Details | ||
| Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 3802) | Kaohsiung | 83301 | Taiwan | Details | ||
| National Cheng Kung University Hospital-Clinical Trial Center ( Site 3803) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital-Oncology ( Site 3801) | Taipei | 10002 | Taiwan | Details | ||
| St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 3206) | London | London, City Of | EC1A 7BE | United Kingdom | Details | |
| ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 3201) | London | London, City Of | SW3 6JJ | United Kingdom | Details |