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| NCT ID | NCT05894239 |
| Title | A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | POL | ITA | GBR | FRA | FIN | ESP | DEU | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Banner Health MD Anderson AZ | RECRUITING | Gilbert | Arizona | 85234 | United States | Details |
| Disney Family Cancer Center | RECRUITING | Burbank | California | 91505 | United States | Details |
| Lawrence J. Ellison Institute for Transformative Medicine | RECRUITING | Los Angeles | California | 90064 | United States | Details |
| Georgetown Uni Hospital; 4-N Main Hospital | RECRUITING | Washington | District of Columbia | 20007 | United States | Details |
| Medstar Research Institute | RECRUITING | Hyattsville | Maryland | 20783 | United States | Details |
| Dana Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Henry Ford Hospital | RECRUITING | Detroit | Michigan | 48202 | United States | Details |
| Hackensack University Medical Center | RECRUITING | Hackensack | New Jersey | 07601 | United States | Details |
| Atrium Health | RECRUITING | Charlotte | North Carolina | 28209 | United States | Details |
| Hightower Clinical | RECRUITING | Oklahoma City | Oklahoma | 73102 | United States | Details |
| Lumi Research | WITHDRAWN | Kingwood | Texas | 77339 | United States | Details |
| Kadlec Clinic Hematology and Oncology | RECRUITING | Kennewick | Washington | 99336-7774 | United States | Details |
| Swedish Medical Center | RECRUITING | Seattle | Washington | 98104-1360 | United States | Details |
| Fundación CENIT para la Investigación en Neurociencias | ACTIVE_NOT_RECRUITING | Buenos Aires | C1125ABD | Argentina | Details | |
| Centro Oncologico Korben; Oncology | RECRUITING | Ciudad Autonoma Buenos Aires | C1426AGE | Argentina | Details | |
| Instituto de Oncología de Rosario | RECRUITING | Rosario | S2000KZE | Argentina | Details | |
| Hospital Provincial del Centenario | RECRUITING | Rosario | S2002KDS | Argentina | Details | |
| CER San Juan Centro Polivalente de Asistencia e Investigacion Clinica | RECRUITING | San Juan | J5400DIL | Argentina | Details | |
| Clínica Viedma | RECRUITING | Viedma Rio Negro | R8500ACE | Argentina | Details | |
| Blacktown Hospital | RECRUITING | Blacktown | New South Wales | 2148 | Australia | Details |
| Kinghorn Cancer Centre; St Vincents Hospital | RECRUITING | Darlinghurst | New South Wales | 2010 | Australia | Details |
| Gosford Hospital; Cancer Care Services | RECRUITING | Gosford | New South Wales | 2250 | Australia | Details |
| University of the Sunshine Coast | RECRUITING | Sippy Downs | Queensland | 4556 | Australia | Details |
| Monash Health | RECRUITING | Clayton | Victoria | 3168 | Australia | Details |
| Sir Charles Gairdner Hospital; Medical Oncology | RECRUITING | Perth | Western Australia | 6009 | Australia | Details |
| Cliniques Universitaires St-Luc | RECRUITING | Bruxelles | 1200 | Belgium | Details | |
| GHdC Site Notre Dame | RECRUITING | Charleroi | 6000 | Belgium | Details | |
| Jessa Zkh (Campus Virga Jesse) | RECRUITING | Hasselt | 3500 | Belgium | Details | |
| Clinique Ste-Elisabeth | RECRUITING | Namur | 5000 | Belgium | Details | |
| Hospital Sao Rafael - HSR | RECRUITING | Salvador | BA | 41253-190 | Brazil | Details |
| Crio - Centro Regional Integrado de Oncologia | RECRUITING | Fortaleza | CE | 60336-232 | Brazil | Details |
| Hospital Araujo Jorge; Departamento de Ginecologia E Mama | RECRUITING | Goiania | GO | 74605-070 | Brazil | Details |
| Hospital do Cancer de Pernambuco - HCP | RECRUITING | Recife | PE | 50040-000 | Brazil | Details |
| Hospital do Câncer de Londrina | RECRUITING | Londrina | PR | 86015-520 | Brazil | Details |
| Hospital de Amor Amazônia | RECRUITING | Porto Velho | RO | 76834-899 | Brazil | Details |
| Santa Casa de Misericordia de Porto Alegre | ACTIVE_NOT_RECRUITING | Porto Alegre | RS | 90020-090 | Brazil | Details |
| Hospital Sao Lucas - PUCRS | RECRUITING | Porto Alegre | RS | 90610-000 | Brazil | Details |
| Hospital de Cancer de Barretos | RECRUITING | Barretos | SP | 14784-400 | Brazil | Details |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | RECRUITING | Sao Paulo | SP | 01246-000 | Brazil | Details |
| Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda | RECRUITING | Sao Paulo | SP | 01317-001 | Brazil | Details |
| Tom Baker Cancer Centre-Calgary | RECRUITING | Calgary | Alberta | T2N 4N2 | Canada | Details |
| The Moncton Hospital | RECRUITING | Moncton | New Brunswick | E1C 6Z8 | Canada | Details |
| Eastern Health - General Hospital | RECRUITING | St. John's | Newfoundland and Labrador | A1B 3V6 | Canada | Details |
| Jewish General Hospital | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Hôpital du Sacré-Coeur de Montreal | RECRUITING | Montreal | Quebec | H4J 1C5 | Canada | Details |
| Hopital du Saint Sacrement | RECRUITING | Quebec City | Quebec | G1S 4L8 | Canada | Details |
| Allan Blair Cancer Center | RECRUITING | Regina | Saskatchewan | S4T 7T1 | Canada | Details |
| Affiliated Hospital of Hebei University; Department of medical oncology | RECRUITING | Baoding | 071000 | China | Details | |
| Beijing Cancer Hospital | RECRUITING | Beijing | 100142 | China | Details | |
| The First Hospital of Jilin University | RECRUITING | Changchun City | 130021 | China | Details | |
| Sichuan Provincial Cancer Hospital | RECRUITING | Chengdu | 610041 | China | Details | |
| Sichuan Provincial People's Hospital | RECRUITING | Chengdu | 610072 | China | Details | |
| Fujian Cancer Hospital | RECRUITING | Fuzhou | 350014 | China | Details | |
| The Second Affiliated Hospital of Zhejiang University School of Medicine | WITHDRAWN | Hangzhou City | 310009 | China | Details | |
| Zhejiang Cancer Hospital; Breast Surgery | RECRUITING | Hangzhou City | 310022 | China | Details | |
| Harbin Medical University Tumor Hospital; Department of Surgery; Pharmacy | RECRUITING | Harbin | 150049 | China | Details | |
| Shandong Cancer Hospital | RECRUITING | Jinan | 250117 | China | Details | |
| The First Affiliated Hospital to Henan University of Science and Technology | RECRUITING | Luoyang City | 471031 | China | Details | |
| The Second Affiliated Hospital to Nanchang University | RECRUITING | Nanchang | 330006 | China | Details | |
| Guangxi Cancer Hospital of Guangxi Medical University | RECRUITING | Nanning City | 530021 | China | Details | |
| Shantou Center Hospital | RECRUITING | Shantou City | 515031 | China | Details | |
| Tianjin Cancer Hospital; Department of Breast Oncology | RECRUITING | Tianjin | 300000 | China | Details | |
| Union Hospital Tongji Medical College Huazhong University of Science and Technology | RECRUITING | Wuhan City | 430023 | China | Details | |
| Hubei Cancer Hospital | RECRUITING | Wuhan | 430079 | China | Details | |
| Clinica De La Costa | COMPLETED | Barranquilla | 080020 | Colombia | Details | |
| Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo | RECRUITING | Bogota, D.C. | 110131 | Colombia | Details | |
| Oncomedica S.A. | RECRUITING | Monteria | 230002 | Colombia | Details | |
| Tampere University Hospital; Dept of Oncology | RECRUITING | Tampere | 33520 | Finland | Details | |
| Turku Uni Central Hospital; Oncology Clinics | RECRUITING | Turku | 20520 | Finland | Details | |
| Institut Sainte Catherine | RECRUITING | Avignon | 84082 | France | Details | |
| Centre Hospitalier de La Cote Basque; Oncologie | RECRUITING | Bayonne | 64109 | France | Details | |
| Polyclinique Bordeaux Nord Aquitaine | RECRUITING | Bordeaux | 33300 | France | Details | |
| Klinikum St. Marien; Frauenklinik | RECRUITING | Amberg | 92224 | Germany | Details | |
| Marienhospital Bottrop gGmbH; Department of Gynecology and Obstetrics | RECRUITING | Bottrop | 46236 | Germany | Details | |
| Gynonco Düsseldorf, MVZ Medical Center GmbH | RECRUITING | Düsseldorf | 40235 | Germany | Details | |
| Frauenarztpraxis Dr. Apel, Dr. Kolpin | RECRUITING | Erfurt | 99084 | Germany | Details | |
| Praxis für Interdisziplinäre Onkologie und Hämatologie GbR | RECRUITING | Freiburg | 79110 | Germany | Details | |
| Klinik & Poliklinik für Frauenheilkunde und Geburtshilfe, Campus Innenstadt | RECRUITING | München | 80336 | Germany | Details | |
| Caritas Klinik St. Theresia -Frauenklinik Brustzentrum | RECRUITING | Saarbruecken | 66113 | Germany | Details | |
| Gynäkologie Kompetenzzentrum; Praxis Dr. med. Carsten Hielscher | RECRUITING | Stralsund | 18439 | Germany | Details | |
| Queen Mary Hospital; Dept. of Clinical Oncology | RECRUITING | Hong Kong | Hong Kong | Details | ||
| Tuen Mun Hospital; Clinical Oncology | RECRUITING | Hong Kong | Hong Kong | Details | ||
| Max Super Speciality Hospital; Oncology | RECRUITING | NEW Delhi Delhi | Delhi | 110092 | India | Details |
| Sunshine Global Hospital (A unit of Baroda Medicare Pvt Ltd) | RECRUITING | Surat CITY | Gujarat | 395007 | India | Details |
| Artemis Hospital | RECRUITING | Gurugram | Haryana | 122001 | India | Details |
| Tata Medical Center | RECRUITING | Kolkata | WEST Bengal | 700160 | India | Details |
| I.R.S.T Srl IRCCS; Oncologia Medica | RECRUITING | Meldola | Emilia-Romagna | 47014 | Italy | Details |
| Ospedale San Giovanni Addolorata; Oncologia | RECRUITING | Roma | Lazio | 00185 | Italy | Details |
| Ospedale San Raffaele; Medical Oncology | RECRUITING | Milano | Lombardia | 20132 | Italy | Details |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1 | RECRUITING | Milano | Lombardia | 20133 | Italy | Details |
| Irccs Istituto Europeo Di Oncologia (IEO); Ricerca Di Senologia Medica | RECRUITING | Milano | Lombardia | 20141 | Italy | Details |
| Ospedale San Gerardo; Centro Di Ricerca di Fase I ? Piano 8 ? Settore C | RECRUITING | Monza | Lombardia | 20900 | Italy | Details |
| A.O.U. Maggiore della Carità | RECRUITING | Novara | Piemonte | 28100 | Italy | Details |
| Casa di Cura La Maddalena; Oncologia Medica | RECRUITING | Palermo | Sicilia | 90146 | Italy | Details |
| Ospedale Santa Maria Annunziata; Oncologia | RECRUITING | Bagno a Ripoli | Toscana | 50012 | Italy | Details |
| "Azienda Ospedaliera Universitaria Integrata Verona Ospedale Borgo Trento" | RECRUITING | Verona | Veneto | 37124 | Italy | Details |
| King Hussein Cancer Center | RECRUITING | Amman | 11941 | Jordan | Details | |
| University of Nairobi - Institute of Tropical and Infectious Diseases | RECRUITING | Nairobi | 19676-00202 | Kenya | Details | |
| National Cancer Center | ACTIVE_NOT_RECRUITING | Goyang-si | 10408 | Korea, Republic of | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | ACTIVE_NOT_RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Asan Medical Center | ACTIVE_NOT_RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| Gangnam Severance Hospital | RECRUITING | Seoul | 06273 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Seoul St Mary's Hospital | RECRUITING | Seoul | 06591 | Korea, Republic of | Details | |
| Hospital Civil de Guadalajara Fray Antonio Alcalde | RECRUITING | Guadalajara | Jalisco | 44280 | Mexico | Details |
| OncoMed; Supportive Care | RECRUITING | Ciudad de México | Mexico CITY (federal District) | 03100 | Mexico | Details |
| Centro Oncológico Hematológico Roma | RECRUITING | Mexico City | Mexico CITY (federal District) | 06700 | Mexico | Details |
| Hospital Universitario; Dr. Jose E. Gonzalez | RECRUITING | Monterrey | Nuevo LEON | 64460 | Mexico | Details |
| Hospital Zambrano Hellion TecSalud | WITHDRAWN | Monterrey | Nuevo LEON | 66278 | Mexico | Details |
| CENEIT Oncologicos; DENTRO DE CONDOMINIO SAN FRANCISCO | RECRUITING | Mexico City | 03100 | Mexico | Details | |
| Centrum Onkologii im. Prof. Franciszka ?ukaszczyka; Ambulatorium Chemioterapii | RECRUITING | Bydgoszcz | 85-796 | Poland | Details | |
| Uniwersyteckie Centrum Kliniczne; Klinika Onkologii i Radioterapii | RECRUITING | Gdansk | 80-214 | Poland | Details | |
| Szpital Morski im.PCK; Oddzial Onkologii Klinicznej, Oddzial Dzienny | RECRUITING | Gdynia | 81-519 | Poland | Details | |
| Narodowy Instytut Onkologii Odzia? w Gliwicach; Centrum Diagnostyki i Leczenia Chorób Piersi | RECRUITING | Gliwice | 44-102 | Poland | Details | |
| Przychodnia Lekarska KOMED, Roman Karaszewski | RECRUITING | Konin | 62-500 | Poland | Details | |
| Szpital Wojewódzki im. Miko?aja Kopernika; Oddzia? Dzienny Chemioterapii | RECRUITING | Koszalin | 75-581 | Poland | Details | |
| Centrum Onkologii Instytut im.M. Sklodowskiej-Curie; Klin. Nowot. Piersii i Chirurgii Rekonstruk | RECRUITING | Warszawa | 02-781 | Poland | Details | |
| National University Hospital; National University Cancer Institute, Singapore (NCIS) | RECRUITING | Singapore | 119228 | Singapore | Details | |
| National Cancer Centre; Medical Oncology | ACTIVE_NOT_RECRUITING | Singapore | 168583 | Singapore | Details | |
| Icon Cancer Centre Farrer Park | RECRUITING | Singapore | 217562 | Singapore | Details | |
| Tan Tock Seng Hospital; Oncology | RECRUITING | Singapore | 308433 | Singapore | Details | |
| Hopelands Cancer Centre | RECRUITING | Hilton | 3245 | South Africa | Details | |
| Charlotte Maxeke Academic Hospital | RECRUITING | Johannesburg | 2193 | South Africa | Details | |
| Medical Oncology Centre of Rosebank; Oncology | RECRUITING | Johannesburg | 2196 | South Africa | Details | |
| Limpopo Cancer Research Institute | RECRUITING | Polokwane | 0700 | South Africa | Details | |
| Steve Biko Academic Hospital; Oncology | RECRUITING | Pretoria | 0002 | South Africa | Details | |
| Chris Hani Baragwanath Clinical Trial Site | ACTIVE_NOT_RECRUITING | Soweto | 2013 | South Africa | Details | |
| Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia | RECRUITING | A Coruña | LA Coruña | 15006 | Spain | Details |
| Hospital Universitari Dexeus - Grupo Quironsalud; Servicio de Oncologia Medica | RECRUITING | Barcelona | 08028 | Spain | Details | |
| Hospital Universitari Vall d'Hebron | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital General Universitario Gregorio Marañon; Servicio de Oncologia | RECRUITING | Madrid | 28009 | Spain | Details | |
| Hospital Ramon y Cajal; Servicio de Oncologia | RECRUITING | Madrid | 28034 | Spain | Details | |
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | ACTIVE_NOT_RECRUITING | Madrid | 28041 | Spain | Details | |
| Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia | RECRUITING | Malaga | 29010 | Spain | Details | |
| Hospital Universitario Virgen Macarena; Servicio de Oncologia | RECRUITING | Sevilla | 41009 | Spain | Details | |
| National Taiwan Uni Hospital; General Surgery | RECRUITING | Taipei | 100 | Taiwan | Details | |
| Tri-Service General Hospital; Department of Haematology and Oncology | RECRUITING | Taipei | Taiwan | Details | ||
| Chang Gung Memorial Hospital-Linkou; Dept of Oncology | RECRUITING | Taoyuan County | 333 | Taiwan | Details | |
| Gazi University Medical Faculty | RECRUITING | Ankara | 06500 | Turkey | Details | |
| Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji | RECRUITING | Bakirkoy / Istanbul | 34147 | Turkey | Details | |
| Dicle University Faculty of Medicine | RECRUITING | Diyarbakir | 21280 | Turkey | Details | |
| Medipol Mega Üniversite Hastanesi Göztepe | RECRUITING | Istanbul | 34214 | Turkey | Details | |
| Katip Celebi University Ataturk Training and Research Hospital; Oncology | RECRUITING | Izmir | 35360 | Turkey | Details | |
| Medical Park Seyhan Hospital; Oncology Department | ACTIVE_NOT_RECRUITING | Seyhan | 01140 | Turkey | Details | |
| Hacettepe Uni Medical Faculty Hospital; Oncology Dept | RECRUITING | Sihhiye/Ankara | 06230 | Turkey | Details | |
| Blackpool Victoria Hospital | RECRUITING | Blackpool | FY3 8NR | United Kingdom | Details | |
| Colchester General Hospital | RECRUITING | Colchester, Essex | CO4 5JL | United Kingdom | Details | |
| Mount Vernon Hospital; Centre For Cancer Treatment | RECRUITING | Northwood | HA6 2RN | United Kingdom | Details | |
| Nottingham City Hospital; Oncology | RECRUITING | Nottingham | NG5 1PB | United Kingdom | Details | |
| Churchill Hospital; Oxford Cancer and Haematology Centre | RECRUITING | Oxford | OX3 7LJ | United Kingdom | Details |