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| NCT ID | NCT05907304 |
| Title | A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations (SEACRAFT-1) |
| Acronym | SEACRAFT-1 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | Yes |
| Sponsors | Erasca, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | child | adult | senior |
| Covered Countries | USA | GBR | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama | WITHDRAWN | Birmingham | Alabama | 35294 | United States | Details |
| University of California, San Francisco | RECRUITING | San Francisco | California | 94143 | United States | Details |
| Yale Cancer Center | COMPLETED | New Haven | Connecticut | 06510 | United States | Details |
| Florida Cancer Specialists - St. Petersburg | RECRUITING | Saint Petersburg | Florida | 33705 | United States | Details |
| Florida Cancer Specialists - Sarasota | RECRUITING | Sarasota | Florida | 34232 | United States | Details |
| Emory University School of Medicine | ACTIVE_NOT_RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Henry Ford Health System | COMPLETED | Detroit | Michigan | 48202 | United States | Details |
| Washington University School of Medicine | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| Comprehensive Cancer Center of Nevada (CCCN) | ACTIVE_NOT_RECRUITING | Las Vegas | Nevada | 89169 | United States | Details |
| Oregon Health & Science University | RECRUITING | Portland | Oregon | 97239 | United States | Details |
| SCRI Oncology Partners (formerly Tennessee Oncology) | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| The University of Texas MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Inova Schar Cancer Institute | ACTIVE_NOT_RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| NEXT Virginia | ACTIVE_NOT_RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| University of Wisconsin | ACTIVE_NOT_RECRUITING | Madison | Wisconsin | 53792 | United States | Details |
| Macquarie University | ACTIVE_NOT_RECRUITING | Macquarie Park | New South Wales | Australia | Details | |
| St. Vincent's Hospital | ACTIVE_NOT_RECRUITING | Melbourne | Victoria | Australia | Details | |
| Linear Clinical Research, LTD | ACTIVE_NOT_RECRUITING | Perth | Australia | Details | ||
| Cross Cancer Institute- Alberta Health Services (AHS) | ACTIVE_NOT_RECRUITING | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| British Columbia Cancer Agency | RECRUITING | Vancouver | British Columbia | V5Z 4E6 | Canada | Details |
| London Regional Cancer Center | RECRUITING | London | Ontario | Canada | Details | |
| Princess Margaret Cancer Centre | ACTIVE_NOT_RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Inje University Haeundae Paik Hospital | ACTIVE_NOT_RECRUITING | Busan | Busan Gwang'yeogsi | 48108 | Korea, Republic of | Details |
| Samsung Medical Center | ACTIVE_NOT_RECRUITING | Seoul | Seoul Teugbyeolsi | 06351 | Korea, Republic of | Details |
| National Cancer Center | ACTIVE_NOT_RECRUITING | Goyang-si | Korea, Republic of | Details | ||
| Seoul National University Hospital Bundang | ACTIVE_NOT_RECRUITING | Gyeonggi-do | Korea, Republic of | Details | ||
| Seoul National University Hospital | ACTIVE_NOT_RECRUITING | Seoul | Korea, Republic of | Details | ||
| The Catholic University Hospital | ACTIVE_NOT_RECRUITING | Seoul | Korea, Republic of | Details | ||
| Sarah Cannon Research Institute - HCA Healthcare | RECRUITING | City Of London | London | W1G 6AD | United Kingdom | Details |
| Beatson West of Scotland Cancer Center | RECRUITING | Glasgow | United Kingdom | Details |