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| NCT ID | NCT05933577 |
| Title | A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | POL | NZL | ITA | ISR | GRC | GBR | FRA | ESP | DNK | DEU | CHE | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Aalborg Universitetshospital, Syd ( Site 3302) | Aalborg | Nordjylland | 9000 | Denmark | Details | |
| Acibadem Universitesi Atakent Hastanesi-Medical Oncology ( Site 3008) | Istanbul | 34303 | Turkey | Details | ||
| Addenbrooke's Hospital ( Site 1800) | Cambridge | Cambridgeshire | CB2 2QQ | United Kingdom | Details | |
| Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 3002) | Ankara | 06800 | Turkey | Details | ||
| AO Santa Maria della Misericordia ( Site 1403) | Perugia | Umbria | 06129 | Italy | Details | |
| Assistance Publique Hôpitaux de Marseille - Hôpital de la Ti-Service de Dermatologie et Cancérologi | Marseille | Bouches-du-Rhone | 13385 | France | Details | |
| Atlantic Health System ( Site 1925) | Morristown | New Jersey | 07960 | United States | Details | |
| AZ Groeninge Campus Kennedylaan-Oncology ( Site 3401) | Kortrijk | West-Vlaanderen | 8500 | Belgium | Details | |
| Azienda Ospedaliero Universitaria Senese-U.O.C. Immunoterapia Oncologica ( Site 1402) | Siena | Toscana | 53100 | Italy | Details | |
| BC Cancer Vancouver-Clinical Trials Unit ( Site 1106) | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Beth Israel Deaconess Medical Center ( Site 1957) | Boston | Massachusetts | 02215 | United States | Details | |
| Bialostockie Centrum Onkologii ( Site 2905) | Bialystok | Podlaskie | 15-027 | Poland | Details | |
| Bioclinic Thessalonikis Private Clinic Single Member S.A.-Oncology ( Site 3703) | Thessaloniki | Kentriki Makedonia | 546 22 | Greece | Details | |
| Bradfordhill ( Site 2401) | Santiago | Region M. De Santiago | 8420383 | Chile | Details | |
| Bristol Haematology and Oncology Centre ( Site 1811) | Bristol | Bristol, City Of | BS2 8ED | United Kingdom | Details | |
| Cancer and Hematology Centers of Western Michigan ( Site 1932) | Grand Rapids | Michigan | 49503 | United States | Details | |
| Cape Town Oncology Trials ( Site 4100) | Cape Town | Western Cape | 7570 | South Africa | Details | |
| Capital, Coast and Hutt Valley District - Wellington Regional Hospital ( Site 1502) | Newtown | Wellington | 6021 | New Zealand | Details | |
| Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 1206) | Rennes | Ille-et-Vilaine | 35042 | France | Details | |
| Centre Georges François Leclerc ( Site 1210) | Dijon | Cote-d Or | 21079 | France | Details | |
| Centre Hospitalier de l'Université de Montréal-Unité de Recherche Clinique en Oncologie et Hématolo | Montréal | Quebec | H2X 0X9 | Canada | Details | |
| centre hospitalier lyon sud-Service de dermatologie ( Site 1202) | Pierre-Bénite | Rhone | 69310 | France | Details | |
| Centre Hospitalier Universitaire de Nice - Hôpital l'Archet-Dermatology Department ( Site 1211) | Nice cedex 3 | Alpes-Maritimes | 06200 | France | Details | |
| Centre intégré de cancérologie du CHU de Québec Université L-Hemato-Oncology ( Site 1101) | Quebec City | Quebec | G1J 1Z4 | Canada | Details | |
| Centro Avançado de Tratamento Oncológico- CENANTRON ( Site 2303) | Belo Horizonte | Minas Gerais | 30130-090 | Brazil | Details | |
| Centro Privado de RMI Río Cuarto S.A. II ( Site 2201) | Río Cuarto | Cordoba | X5800ALB | Argentina | Details | |
| Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2908) | Bydgoszcz | Kujawsko-pomorskie | 85-796 | Poland | Details | |
| Chang Gung Medical Foundation-Linkou Branch ( Site 4003) | Taoyuan | 33305 | Taiwan | Details | ||
| Chang Gung Memorial Hospital at Kaohsiung (Site 4000) | Kaohsiung | 83301 | Taiwan | Details | ||
| Charité Universitaetsmedizin Berlin - Campus Mitte-Hauttumorcentrum Charité (HTCC) ( Site 1302) | Berlin | 10115 | Germany | Details | ||
| CHU Besançon ( Site 1209) | Besançon | Doubs | 25030 | France | Details | |
| CHU d'Amiens-Picardie - Hôpital Sud-Dermatologie ( Site 1208) | Amiens | Somme | 80054 | France | Details | |
| CHU de Bordeaux Hop St ANDRE-Service de Dermatologie ( Site 1204) | Bordeaux | Gironde | 33075 | France | Details | |
| Chungnam national university hospital-Department of Internal Medicine ( Site 3903) | Daejeon | Taejon-Kwangyokshi | 35015 | Korea, Republic of | Details | |
| Clinica Adventista Belgrano-Oncology ( Site 2204) | Caba | 1430 | Argentina | Details | ||
| Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 2500) | Bogota | Distrito Capital De Bogota | 111321 | Colombia | Details | |
| Clinica Somer-Unidad de Investigacion y Docencia ( Site 2506) | Rionegro | Antioquia | 054040 | Colombia | Details | |
| Clínica UC San Carlos de Apoquindo-Hemato-Oncology ( Site 2402) | Santiago | Region M. De Santiago | 7620002 | Chile | Details | |
| Columbia University Irving Medical Center-CUIMC Herbert Irving Comprehensive Cancer Center Clinical | New York | New York | 10032 | United States | Details | |
| Cross Cancer Institute ( Site 1104) | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Dana-Farber Cancer Institute ( Site 1956) | Boston | Massachusetts | 02215 | United States | Details | |
| Duke Cancer Institute ( Site 1911) | Durham | North Carolina | 27710 | United States | Details | |
| Ege University Medical Faculty Hospital ( Site 3011) | Izmir | 35100 | Turkey | Details | ||
| Emek Medical Center ( Site 2003) | Afula | 1834111 | Israel | Details | ||
| European Interbalkan Medical Center-Oncology Department ( Site 3702) | Thessaloniki | 57001 | Greece | Details | ||
| FALP-UIDO ( Site 2400) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 1401) | Milan | Lombardia | 20133 | Italy | Details | |
| Fred Hutchinson Cancer Center ( Site 1901) | Seattle | Washington | 98109 | United States | Details | |
| Fundación Valle del Lili ( Site 2505) | Cali | Valle Del Cauca | 760032 | Colombia | Details | |
| General Hospital of Athens "Laiko"-First Department of Internal Medicine ( Site 3700) | Athens | Attiki | 115 26 | Greece | Details | |
| Gustave Roussy-Dermatologie ( Site 1201) | Villejuif | Val-de-Marne | 94800 | France | Details | |
| H.R.U Málaga - Hospital General-Oncology ( Site 1605) | Málaga | Malaga | 29011 | Spain | Details | |
| Hacettepe Universite Hastaneleri ( Site 3006) | Ankara | 06230 | Turkey | Details | ||
| Hadassah Medical Center ( Site 2004) | Jerusalem | 9112001 | Israel | Details | ||
| Harbour Cancer & Wellness ( Site 1500) | Auckland | 1023 | New Zealand | Details | ||
| Herlev and Gentofte Hospital ( Site 3301) | Copenhagen | Hovedstaden | 2730 | Denmark | Details | |
| Highlands Oncology Group ( Site 1943) | Springdale | Arkansas | 72762 | United States | Details | |
| Hopital Claude Huriez - CHU de Lille ( Site 1207) | Lille | Nord | 59037 | France | Details | |
| Hospital Aleman ( Site 2200) | Buenos Aires | C1118AAT | Argentina | Details | ||
| HOSPITAL CLINICO DE VALENCIA ( Site 1604) | Valencia | Valenciana, Comunitat | 46010 | Spain | Details | |
| HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Sit | Barcelona | Cataluna | 08036 | Spain | Details | |
| Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 2202) | Caba | Buenos Aires | C1199ABB | Argentina | Details | |
| Hospital Nossa Senhora da Conceição ( Site 2309) | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details | |
| Hospital of the University of Pennsylvania Perelman Center for Advanced Medicine ( Site 1905) | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1601) | Barcelona | 08035 | Spain | Details | ||
| HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1603) | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details | |
| Hospital Universitario Ramón y Cajal ( Site 1602) | Madrid | Madrid, Comunidad De | 28034 | Spain | Details | |
| Hôpital Saint-Louis ( Site 1200) | Paris | 75010 | France | Details | ||
| I.E.U. Medical Point Hastanesi-Oncology ( Site 3005) | Izmir | 35575 | Turkey | Details | ||
| ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO ( Site 2300) | Sao Paulo | 01246-000 | Brazil | Details | ||
| Inova Schar Cancer Institute ( Site 1900) | Fairfax | Virginia | 22031 | United States | Details | |
| Instituto Alexander Fleming-Alexander Fleming ( Site 2203) | Ciudad Autónoma de Buenos Aires | Caba | 1426 | Argentina | Details | |
| Instituto Nacional de Câncer - INCA-Pesquisa Clinica HC II ( Site 2305) | Rio de Janeiro | 20220-410 | Brazil | Details | ||
| Instituto Português de Oncologia de Lisboa Francisco Gentil ( Site 3601) | Lisbon | Lisboa | 1099-023 | Portugal | Details | |
| Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 3604) | Porto | 4200-072 | Portugal | Details | ||
| Istituto Europeo di Oncologia IRCCS ( Site 1404) | Milano | Lombardia | 20141 | Italy | Details | |
| Istituto Nazionale Tumori IRCCS Fondazione Pascale-s.c. melanoma, immunoterapia oncologica e terapi | Napoli | 80131 | Italy | Details | ||
| Johannes Wesling Klinikum Minden-Skin Cancer Center Minden ( Site 1301) | Minden | Nordrhein-Westfalen | 32429 | Germany | Details | |
| John Theurer Cancer Center at Hackensack University Medical Center ( Site 1944) | Hackensack | New Jersey | 07601 | United States | Details | |
| Johns Hopkins Hospital-Sidney Kimmel Comprehensive Cancer Center - Melanoma ( Site 1912) | Baltimore | Maryland | 21287 | United States | Details | |
| Kantonsspital Graubünden-Medizin ( Site 1703) | Chur | Grisons | 7000 | Switzerland | Details | |
| Klinik und Poliklinik für Dermatologie und Allergologie-Dermato-oncology ( Site 1315) | München | Bayern | 80337 | Germany | Details | |
| Kyungpook National University Chilgok Hospital-Hematology/oncology ( Site 3904) | Daegu | Taegu-Kwangyokshi | 41404 | Korea, Republic of | Details | |
| Massachusetts General Hospital ( Site 1927) | Boston | Massachusetts | 02114 | United States | Details | |
| Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 2903) | Siedlce | Mazowieckie | 08-110 | Poland | Details | |
| Medical Oncology Centre of Rosebank ( Site 4106) | Johannesburg | Gauteng | 2196 | South Africa | Details | |
| Medical University of South Carolina-Hollings Cancer Center ( Site 1934) | Charleston | South Carolina | 29425 | United States | Details | |
| Melanoma Institute Australia-Clinical Trials Unit ( Site 1000) | Wollstonecraft | New South Wales | 2065 | Australia | Details | |
| Memorial Ankara Hastanesi-Medical Oncology ( Site 3010) | Ankara | 06520 | Turkey | Details | ||
| Memorial Sloan Kettering Cancer Center ( Site 1914) | New York | New York | 10065 | United States | Details | |
| Metropolitan Hospital-A' Oncology Dpt ( Site 3701) | Neo Faliro | Attiki | 185 47 | Greece | Details | |
| Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center ( Site 1945) | Tampa | Florida | 33612 | United States | Details | |
| Nagoya University Hospital ( Site 4201) | Nagoya | Aichi | 466-8560 | Japan | Details | |
| Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 2907) | Gliwice | Slaskie | 44-101 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| National Cancer Center Hospital ( Site 4200) | Chuo | Tokyo | 104-0045 | Japan | Details | |
| National Cheng Kung University Hospital-Clinical Trial Center ( Site 4004) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital (Site 4001) | Taipei | 10002 | Taiwan | Details | ||
| Norfolk and Norwich University Hospitals NHS Foundation Trust ( Site 1813) | Cringleford | England | NR4 7UY | United Kingdom | Details | |
| Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 1950) | Marietta | Georgia | 30060 | United States | Details | |
| NYU Langone Health-Perlmutter Cancer Center ( Site 1917) | New York | New York | 10016 | United States | Details | |
| Odense Universitetshospital ( Site 3300) | Odense C | Syddanmark | 5000 | Denmark | Details | |
| Oncomedica S.A.S ( Site 2503) | Montería | Cordoba | 230002 | Colombia | Details | |
| ONCOSITE - Centro de Pesquisa Clinica em Oncologia ( Site 2302) | Ijui | Rio Grande Do Sul | 98700-000 | Brazil | Details | |
| One Clinical Research ( Site 1002) | Nedlands | Western Australia | 6009 | Australia | Details | |
| Orlando Health Cancer Institute ( Site 1937) | Orlando | Florida | 32806 | United States | Details | |
| Paula Fox Melanoma & Cancer Centre ( Site 1004) | Melbourne | Victoria | 3004 | Australia | Details | |
| Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 1958) | Mineola | New York | 11501 | United States | Details | |
| Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 1005) | Melbourne | Victoria | 3000 | Australia | Details | |
| Princess Alexandra Hospital ( Site 1003) | Brisbane | Queensland | 4102 | Australia | Details | |
| Princess Margaret Cancer Centre-Division of Medical Oncology and Hematology ( Site 1102) | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Rabin Medical Center ( Site 2000) | Petah Tikva | 4941492 | Israel | Details | ||
| ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 1804) | London | Kensington And Chelsea | SW3 6JJ | United Kingdom | Details | |
| Sahlgrenska Universitetssjukhuset ( Site 3200) | Gothenburg | Vastra Gotalands Lan | 413 45 | Sweden | Details | |
| Samsung Medical Center-Division of Hematology/Oncology ( Site 3900) | Seoul | 06351 | Korea, Republic of | Details | ||
| Sanatorio Finochietto ( Site 2205) | Buenos Aires | C1187AAN | Argentina | Details | ||
| Sanford Cancer Center ( Site 1951) | Sioux Falls | South Dakota | 57104 | United States | Details | |
| SCRI Oncology Partners ( Site 1910) | Nashville | Tennessee | 37203 | United States | Details | |
| Seoul National University Hospital-Oncology ( Site 3902) | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System-Medical oncology ( Site 3901) | Seoul | 03722 | Korea, Republic of | Details | ||
| Sheba Medical Center ( Site 2001) | Ramat Gan | 5265601 | Israel | Details | ||
| Shizuoka Cancer Center ( Site 4202) | Nagaizumi-cho,Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| Skånes Universitetssjukhus Lund ( Site 3201) | Lund | Skane Lan | 22185 | Sweden | Details | |
| SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1306) | Gera | Thuringen | 07548 | Germany | Details | |
| St James's University Hospital-Leeds Cancer Centre ( Site 1808) | Leeds | LS9 7TF | United Kingdom | Details | ||
| Sunnybrook Research Institute ( Site 1103) | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch | Kielce | Swietokrzyskie | 25-734 | Poland | Details | |
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 3003) | Istanbul | 34722 | Turkey | Details | ||
| Texas Oncology - Austin ( Site 1903) | Austin | Texas | 78731 | United States | Details | |
| Texas Oncology - Dallas (Sammons) ( Site 1902) | Dallas | Texas | 75246 | United States | Details | |
| The Christie NHS Foundation Trust ( Site 1814) | Manchester | m20 4bx | United Kingdom | Details | ||
| The Churchill Hospital ( Site 1805) | Oxford | Oxfordshire | OX3 7LE | United Kingdom | Details | |
| UCLA Hematology/Oncology - Westwood (Building 100) ( Site 1918) | Los Angeles | California | 90095 | United States | Details | |
| UCSF Medical Center at Mission Bay ( Site 1929) | San Francisco | California | 94158 | United States | Details | |
| Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 3603) | Lisbon | Lisboa | 1649-035 | Portugal | Details | |
| Unidade Local de Saude Lisboa Ocidental - Hospital de São Francisco Xavier ( Site 3602) | Lisboa | 1449-005 | Portugal | Details | ||
| Universitaetsklinikum Augsburg ( Site 1312) | Augsburg | Bayern | 86156 | Germany | Details | |
| Universitaetsklinikum des Saarlandes ( Site 1313) | Homburg | Saarland | 66424 | Germany | Details | |
| Universitaetsklinikum Essen-Klinik für Dermatologie, Venerologie und Allergologie ( Site 1300) | Essen | Nordrhein-Westfalen | 45147 | Germany | Details | |
| Universitaetsklinikum Hamburg-Eppendorf ( Site 1309) | Hamburg | 20246 | Germany | Details | ||
| Universitaetsklinikum Koeln ( Site 1307) | Köln | Nordrhein-Westfalen | 50937 | Germany | Details | |
| University College London Hospital ( Site 1807) | London | London, City Of | NW1 2PG | United Kingdom | Details | |
| University of Iowa-Holden Comprehensive Cancer Center ( Site 1935) | Iowa City | Iowa | 52242 | United States | Details | |
| University of Michigan ( Site 1915) | Ann Arbor | Michigan | 48109 | United States | Details | |
| University of North Carolina Medical Center-Lineberger Comprehensive Cancer Center ( Site 1949) | Chapel Hill | North Carolina | 27599 | United States | Details | |
| University of Texas MD Anderson Cancer Center ( Site 1920) | Houston | Texas | 77030 | United States | Details | |
| Universitätsmedizin Göttingen - Georg-August-Universität-Dermatology ( Site 1308) | Göttingen | Niedersachsen | 37075 | Germany | Details | |
| Universitätsmedizin Mannheim ( Site 1305) | Mannheim | Baden-Wurttemberg | 68167 | Germany | Details | |
| Universitätsmedizin Rostock-Klinik und Poliklinik für Dermatologie und Venerologie ( Site 1310) | Rostock | Mecklenburg-Vorpommern | 18057 | Germany | Details | |
| UniversitätsSpital Zürich-Dermatology ( Site 1700) | Zürich Flughafen | Zurich | 8058 | Switzerland | Details | |
| Uniwersytecki Szpital Kliniczny w Poznaniu ( Site 2909) | Poznan | Wielkopolskie | 60-569 | Poland | Details | |
| Uniwersyteckie Centrum Kliniczne-Klinika Chirurgii Onkologicznej, Transplantacyjnej i Ogólnej ( Site | Gdańsk | Pomorskie | 80-214 | Poland | Details | |
| UPMC Hillman Cancer Center ( Site 1909) | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| UZ Brussel-Medische oncologie ( Site 3405) | Brussels | Bruxelles-Capitale, Region De | 1090 | Belgium | Details | |
| UZ Gent ( Site 3403) | Gent | Oost-Vlaanderen | 9000 | Belgium | Details | |
| UZ Leuven ( Site 3400) | Leuven | Vlaams-Brabant | 3000 | Belgium | Details | |
| Valley Health Systems - Ridgewood Campus ( Site 1947) | Ridgewood | New Jersey | 07450 | United States | Details | |
| Western General Hospital ( Site 1806) | Edinburgh | Midlothian | EH4 2XU | United Kingdom | Details | |
| Westmead Hospital-Department of Medical Oncology ( Site 1001) | Westmead | New South Wales | 2145 | Australia | Details | |
| Wilgers Oncology Centre ( Site 4103) | Pretoria | Gauteng | 0040 | South Africa | Details | |
| William Osler Health System ( Site 1105) | Brampton | Ontario | L6R 3J7 | Canada | Details | |
| Winship Cancer Institute of Emory University ( Site 1940) | Atlanta | Georgia | 30322 | United States | Details | |
| Yale-New Haven Hospital-Yale Cancer Center ( Site 1933) | New Haven | Connecticut | 06510 | United States | Details | |
| Zachodniopomorskie Centrum Onkologii ( Site 2904) | Szczecin | Zachodniopomorskie | 71-730 | Poland | Details | |
| Ziekenhuis Oost-Limburg, Campus St.-Jan ( Site 3402) | Genk | Limburg | 3600 | Belgium | Details |
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