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| NCT ID | NCT05947500 |
| Title | Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care | RECRUITING | Irvine | California | 92612 | United States | Details |
| Keck Medicine of USC Koreatown | RECRUITING | Los Angeles | California | 90020 | United States | Details |
| Los Angeles General Medical Center | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| USC / Norris Comprehensive Cancer Center | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| USC Norris Oncology/Hematology-Newport Beach | RECRUITING | Newport Beach | California | 92663 | United States | Details |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | RECRUITING | Orange | California | 92868 | United States | Details |
| Yale University | RECRUITING | New Haven | Connecticut | 06520 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Aventura | RECRUITING | Aventura | Florida | 33180 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Coral Gables | RECRUITING | Coral Gables | Florida | 33146 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach | RECRUITING | Deerfield Beach | Florida | 33442 | United States | Details |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | RECRUITING | Miami | Florida | 33136 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Kendall | RECRUITING | Miami | Florida | 33176 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Plantation | RECRUITING | Plantation | Florida | 33324 | United States | Details |
| Moffitt Cancer Center - McKinley Campus | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| Moffitt Cancer Center | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| Emory University Hospital/Winship Cancer Institute | RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Northwestern University | RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| Memorial Hospital East | RECRUITING | Shiloh | Illinois | 62269 | United States | Details |
| University of Kansas Cancer Center | RECRUITING | Kansas City | Kansas | 66160 | United States | Details |
| University of Kansas Cancer Center-Overland Park | RECRUITING | Overland Park | Kansas | 66210 | United States | Details |
| University of Kansas Hospital-Indian Creek Campus | RECRUITING | Overland Park | Kansas | 66211 | United States | Details |
| University of Kansas Hospital-Westwood Cancer Center | RECRUITING | Westwood | Kansas | 66205 | United States | Details |
| Johns Hopkins University/Sidney Kimmel Cancer Center | RECRUITING | Baltimore | Maryland | 21287 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Siteman Cancer Center at West County Hospital | RECRUITING | Creve Coeur | Missouri | 63141 | United States | Details |
| University of Kansas Cancer Center - North | RECRUITING | Kansas City | Missouri | 64154 | United States | Details |
| University of Kansas Cancer Center - Lee's Summit | RECRUITING | Lee's Summit | Missouri | 64064 | United States | Details |
| Washington University School of Medicine | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| Siteman Cancer Center-South County | RECRUITING | Saint Louis | Missouri | 63129 | United States | Details |
| Siteman Cancer Center at Christian Hospital | RECRUITING | Saint Louis | Missouri | 63136 | United States | Details |
| Siteman Cancer Center at Saint Peters Hospital | RECRUITING | Saint Peters | Missouri | 63376 | United States | Details |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | RECRUITING | New York | New York | 10016 | United States | Details |
| Wake Forest University Health Sciences | RECRUITING | Winston-Salem | North Carolina | 27157 | United States | Details |
| University of Oklahoma Health Sciences Center | RECRUITING | Oklahoma City | Oklahoma | 73104 | United States | Details |
| University of Pittsburgh Cancer Institute (UPCI) | RECRUITING | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| UT Southwestern/Simmons Cancer Center-Dallas | RECRUITING | Dallas | Texas | 75390 | United States | Details |
| Huntsman Cancer Institute/University of Utah | RECRUITING | Salt Lake City | Utah | 84112 | United States | Details |
| University of Virginia Cancer Center | RECRUITING | Charlottesville | Virginia | 22908 | United States | Details |
| Virginia Commonwealth University/Massey Cancer Center | RECRUITING | Richmond | Virginia | 23298 | United States | Details |
| Fred Hutchinson Cancer Center | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| University Health Network-Princess Margaret Hospital | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |