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| NCT ID | NCT06074588 |
| Title | Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | ITA | ISR | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mid Florida Hematology and Oncology Center ( Site 0005) | RECRUITING | Orange City | Florida | 32763 | United States | Details |
| Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0003) | RECRUITING | Marietta | Georgia | 30060 | United States | Details |
| Karmanos Cancer Institute ( Site 0018) | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Hattiesburg Clinic Hematology/Oncology ( Site 0010) | RECRUITING | Hattiesburg | Mississippi | 39401 | United States | Details |
| University Of Nebraska Medical Center ( Site 0011) | RECRUITING | Omaha | Nebraska | 68198 | United States | Details |
| Capital Health Medical Center - Hopewell ( Site 0006) | COMPLETED | Pennington | New Jersey | 08534 | United States | Details |
| University of Cincinnati Medical Center-University of Cincinnati Cancer Center ( Site 0015) | RECRUITING | Cincinnati | Ohio | 45219 | United States | Details |
| St. George Private Hospital ( Site 3004) | RECRUITING | Kogarah | New South Wales | 2217 | Australia | Details |
| Westmead Hospital-Department of Medical Oncology ( Site 3000) | RECRUITING | Westmead | New South Wales | 2145 | Australia | Details |
| Monash Health-Oncology Research ( Site 3001) | RECRUITING | Clayton | Victoria | 3168 | Australia | Details |
| Western Health-Sunshine & Footscray Hospitals-Cancer Services-Cancer Research ( Site 3003) | RECRUITING | Melbourne | Victoria | 3021 | Australia | Details |
| Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 0447) | RECRUITING | Natal | Rio Grande Do Norte | 59075-740 | Brazil | Details |
| Hospital Nossa Senhora da Conceição-Centro Integrado de Pesquisa em Oncologia ( Site 0440) | RECRUITING | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details |
| Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0444) | RECRUITING | Barretos | Sao Paulo | 14784-400 | Brazil | Details |
| Hospital Paulistano-Americas Oncologia ( Site 0441) | RECRUITING | Sao Paulo | 01321-001 | Brazil | Details | |
| A. C. Camargo Cancer Center-CAPEC ( Site 0442) | RECRUITING | Sao Paulo | 01509-010 | Brazil | Details | |
| Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 0446) | RECRUITING | Sao Paulo | 04014-002 | Brazil | Details | |
| William Osler Health System ( Site 0205) | RECRUITING | Brampton | Ontario | L6R 3J7 | Canada | Details |
| Princess Margaret Cancer Centre ( Site 0204) | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Centro Investigacion Cancer James Lind ( Site 0513) | RECRUITING | Temuco | Araucania | 4780000 | Chile | Details |
| Clinica Universidad Catolica del Maule-Oncology ( Site 0501) | RECRUITING | Talca | Maule | 3465584 | Chile | Details |
| Orlandi Oncologia-Oncology ( Site 0504) | RECRUITING | Santiago | Region M. De Santiago | 7500713 | Chile | Details |
| FALP-UIDO ( Site 0509) | RECRUITING | Santiago | Region M. De Santiago | 7500921 | Chile | Details |
| Pontificia Universidad Catolica de Chile-Centro del Cáncer ( Site 0502) | RECRUITING | Santiago | Region M. De Santiago | 8330032 | Chile | Details |
| Bradfordhill-Clinical Area ( Site 0507) | RECRUITING | Santiago | Region M. De Santiago | 8420383 | Chile | Details |
| ONCOCENTRO APYS-ACEREY ( Site 0500) | RECRUITING | Viña del Mar | Valparaiso | 2520598 | Chile | Details |
| Beijing Cancer hospital-Thoracic Cancer Department A ( Site 2810) | RECRUITING | Beijing | Beijing | 100142 | China | Details |
| Beijing Peking Union Medical College Hospital-pneumology department ( Site 2815) | RECRUITING | Beijing | Beijing | 100730 | China | Details |
| Chongqing University Cancer Hospital-Medical Oncology ( Site 2814) | RECRUITING | Chongqing | Chongqing | 400030 | China | Details |
| Fujian Cancer Hospital ( Site 2819) | RECRUITING | Fuzhou | Fujian | 350014 | China | Details |
| The First Affiliated hospital of Xiamen University ( Site 2820) | RECRUITING | Xiamen | Fujian | 361003 | China | Details |
| Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( | RECRUITING | Guangzhou | Guangdong | 510515 | China | Details |
| Guangxi Medical University Cancer Hospital-Respiratory Oncology ( Site 2816) | RECRUITING | Nanning | Guangxi | 530200 | China | Details |
| Harbin Medical University Cancer Hospital-oncology of department ( Site 2807) | RECRUITING | Harbin | Heilongjiang | 150081 | China | Details |
| Henan Cancer Hospital-henan cancer hospital ( Site 2813) | RECRUITING | Zhengzhou | Henan | 450000 | China | Details |
| Tongji Hospital Tongji Medical,Science & Technology ( Site 2805) | RECRUITING | Wuhan | Hubei | 430000 | China | Details |
| Wuhan Union Hospital Cancer Center-Cancer Center ( Site 2806) | RECRUITING | Wuhan | Hubei | 430022 | China | Details |
| Hubei Cancer Hospital ( Site 2809) | RECRUITING | Wuhan | Hubei | 430079 | China | Details |
| The Second Xiangya Hospital of Central South University ( Site 2827) | RECRUITING | Changsha | Hunan | 410011 | China | Details |
| Hunan Cancer Hospital-thoracic oncology II ( Site 2808) | RECRUITING | Changsha | Hunan | 410013 | China | Details |
| Nanjing Drum Tower Hospital ( Site 2812) | RECRUITING | Nangjing | Jiangsu | 210008 | China | Details |
| The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2821) | RECRUITING | Nanchang | Jiangxi | 330006 | China | Details |
| Jilin Province Tumor Hospital-clinical research ( Site 2803) | RECRUITING | Changchun | Jilin | 132000 | China | Details |
| The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 2817) | RECRUITING | Xi'an | Shaanxi | 710061 | China | Details |
| Jinan Central Hospital-oncology department ( Site 2802) | RECRUITING | Jinan | Shandong | 250013 | China | Details |
| LinYi Cancer Hospital ( Site 2804) | RECRUITING | Linyi | Shandong | 276001 | China | Details |
| Shanghai Chest Hospital-Oncology department ( Site 2800) | RECRUITING | Shanghai | Shanghai | 200030 | China | Details |
| Fudan University Shanghai Cancer Center-Oncology ( Site 2811) | RECRUITING | Shanghai | Shanghai | 200032 | China | Details |
| Sichuan Cancer hospital. ( Site 2822) | RECRUITING | Chengdu | Sichuan | 610042 | China | Details |
| Yunnan Province Cancer Hospital ( Site 2824) | RECRUITING | Kunming | Yunnan | 650118 | China | Details |
| Sir Run Run Shaw Hospital School of Medicine Zhejiang University ( Site 2828) | RECRUITING | Hangzhou | Zhejiang | 310016 | China | Details |
| Zhejiang Cancer Hospital ( Site 2829) | RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 1100) | RECRUITING | Brno | Brno-mesto | 656 53 | Czechia | Details |
| Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni odd ( Site 1103) | RECRUITING | Ostrava | Ostrava Mesto | 703 00 | Czechia | Details |
| Fakultni nemocnice Plzen ( Site 1104) | RECRUITING | Pilsen | Plzensky Kraj | 305 99 | Czechia | Details |
| Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 1102) | RECRUITING | Olomouc | 779 00 | Czechia | Details | |
| Vseobecna fakultni nemocnice v Praze-Onkologicka klinika ( Site 1105) | RECRUITING | Praha 2 | 122 00 | Czechia | Details | |
| Institut Bergonié - Centre Régional de Lutte Contre Le Cance-Medical Oncology ( Site 1303) | RECRUITING | Bordeaux | Aquitaine | 33076 | France | Details |
| CENTRE LEON BERARD ( Site 1305) | RECRUITING | Lyon Cedex08 | Rhone-Alpes | 69373 | France | Details |
| Institut Curie-Thorax Institute ( Site 1304) | RECRUITING | Paris | 75248 | France | Details | |
| Klinikum Chemnitz - Flemmingstraße ( Site 1401) | RECRUITING | Chemnitz | Sachsen | 09116 | Germany | Details |
| Errikos Dunant Hospital Center-Fourth Department of Oncology and Clinical Trials Unit ( Site 2705) | RECRUITING | Athens | Attiki | 115 26 | Greece | Details |
| THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol | RECRUITING | Athens | Attiki | 115 27 | Greece | Details |
| ATTIKON GENERAL UNIVERSITY HOSPITAL-Oncology ( Site 2704) | RECRUITING | Chaidari, Athens | Attiki | 124 62 | Greece | Details |
| "Theagenio" Cancer Hospital of Thessaloniki ( Site 2703) | RECRUITING | Thessaloniki | Kentriki Makedonia | 540 07 | Greece | Details |
| Papageorgiou General Hospital of Thessaloniki ( Site 2701) | RECRUITING | Thessaloniki | 564 29 | Greece | Details | |
| Hong Kong Integrated Oncology Centre ( Site 3200) | RECRUITING | Central | 0000 | Hong Kong | Details | |
| Queen Mary Hospital ( Site 3203) | RECRUITING | Hksar | Hong Kong | Details | ||
| Queen Elizabeth Hospital-Department of Clinical Oncology ( Site 3204) | RECRUITING | Kowloon | 999077 | Hong Kong | Details | |
| Princess Margaret Hospital-Department of Oncology ( Site 3201) | RECRUITING | Lai Chi Kok | 55555 | Hong Kong | Details | |
| Rambam Health Care Campus-Oncology Division ( Site 1702) | RECRUITING | Haifa | 3109601 | Israel | Details | |
| Shaare Zedek Medical Center ( Site 1700) | RECRUITING | Jerusalem | 9103102 | Israel | Details | |
| Rabin Medical Center ( Site 1703) | RECRUITING | Petah Tikva | 4941492 | Israel | Details | |
| IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 18 | RECRUITING | Meldola | Emilia-Romagna | 47014 | Italy | Details |
| Istituto Clinico Humanitas ( Site 1803) | RECRUITING | Rozzano | Lombardia | 20089 | Italy | Details |
| Aichi Cancer Center Hospital ( Site 3400) | RECRUITING | Nagoya | Aichi | 464-8681 | Japan | Details |
| National Cancer Center Hospital East ( Site 3406) | RECRUITING | Kashiwa | Chiba | 277-8577 | Japan | Details |
| National Hospital Organization Shikoku Cancer Center ( Site 3415) | RECRUITING | Matsuyama | Ehime | 791-0280 | Japan | Details |
| Gunma Prefectural Cancer Center ( Site 3418) | RECRUITING | Otashi | Gunma | 373-8550 | Japan | Details |
| Takarazuka City Hospital ( Site 3409) | RECRUITING | Takarazuka | Hyogo | 665-0827 | Japan | Details |
| Kanazawa University Hospital-Pulmonology ( Site 3414) | RECRUITING | Kanazawa | Ishikawa | 920-8641 | Japan | Details |
| Kanagawa cancer center-Department of Thoracic Oncology ( Site 3404) | RECRUITING | Yokohama | Kanagawa | 241-8515 | Japan | Details |
| Miyagi Cancer Center-Department of Respiratory Medicine ( Site 3416) | RECRUITING | Natori | Miyagi | 981-1293 | Japan | Details |
| Sendai Kousei Hospital ( Site 3401) | RECRUITING | Sendai | Miyagi | 981-0914 | Japan | Details |
| Kansai Medical University Hospital ( Site 3410) | RECRUITING | Hirakata | Osaka | 573-1191 | Japan | Details |
| Shizuoka Cancer Center ( Site 3403) | RECRUITING | Nagaizumi-cho,Sunto-gun | Shizuoka | 411-8777 | Japan | Details |
| The Cancer Institute Hospital of JFCR ( Site 3402) | RECRUITING | Koto | Tokyo | 135-8550 | Japan | Details |
| National Hospital Organization Kyushu Medical Center ( Site 3412) | RECRUITING | Fukuoka | 810-8563 | Japan | Details | |
| Kyushu University Hospital ( Site 3407) | RECRUITING | Fukuoka | 812-8582 | Japan | Details | |
| Okayama University Hospital ( Site 3417) | RECRUITING | Okayama | 700-8558 | Japan | Details | |
| Osaka International Cancer Institute ( Site 3413) | RECRUITING | Osaka | 541-8567 | Japan | Details | |
| Nippon Medical School Hospital ( Site 3408) | RECRUITING | Tokyo | 113-8603 | Japan | Details | |
| Chungbuk National University Hospital-Internal medicine ( Site 3809) | RECRUITING | Cheongju-si | Chungbuk | 28644 | Korea, Republic of | Details |
| Chonnam National University Hwasun Hospital-Pulmonology ( Site 3807) | RECRUITING | Hwasun | Jeonranamdo | 58128 | Korea, Republic of | Details |
| National Cancer Center-Lung Cancer Center ( Site 3810) | RECRUITING | Goyang-si | Kyonggi-do | 10408 | Korea, Republic of | Details |
| Seoul National University Bundang Hospital ( Site 3806) | RECRUITING | Seongnam | Kyonggi-do | 13620 | Korea, Republic of | Details |
| The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 3803) | RECRUITING | Suwon-si | Kyonggi-do | 16247 | Korea, Republic of | Details |
| Pusan National University Yangsan Hospital-Lung Cancer Clinic ( Site 3811) | RECRUITING | Yangsan | Kyongsangnam-do | 50612 | Korea, Republic of | Details |
| Pusan National University Hospital ( Site 3805) | RECRUITING | Busan | Pusan-Kwangyokshi | 49241 | Korea, Republic of | Details |
| Chungnam national university hospital ( Site 3808) | RECRUITING | Jung-gu | Taejon-Kwangyokshi | 35015 | Korea, Republic of | Details |
| Kangbuk Samsung Hospital ( Site 3813) | RECRUITING | Seoul | 03181 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System-Lung Cancer Center ( Site 3804) | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Konkuk University Medical Center ( Site 3812) | RECRUITING | Seoul | 05030 | Korea, Republic of | Details | |
| Asan Medical Center ( Site 3801) | RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| Samsung Medical Center-Division of Hematology/Oncology ( Site 3802) | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Korea University Guro Hospital-Internal Medicine ( Site 3800) | RECRUITING | Seoul | 08308 | Korea, Republic of | Details | |
| Hospital Raja Perempuan Zainab II-Medical Department ( Site 3502) | RECRUITING | Kota Bharu | Kelantan | 15586 | Malaysia | Details |
| National Cancer Institute-Radiotherapy and Oncology ( Site 3504) | RECRUITING | Putrajaya | Kuala Lumpur | 62250 | Malaysia | Details |
| Sarawak General Hospital-Radiotherapy Unit ( Site 3500) | RECRUITING | Kuching | Sarawak | 93586 | Malaysia | Details |
| CIO - Centro de Inmuno-Oncología de Occidente ( Site 0706) | RECRUITING | Guadalajara | Jalisco | 44630 | Mexico | Details |
| Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Hematologia and Oncologia ( Site 0704) | RECRUITING | Monterrey | Nuevo Leon | 66460 | Mexico | Details |
| Centro de Investigacion Clinica de Oaxaca ( Site 0701) | RECRUITING | Oaxaca de Juarez | Oaxaca | 68020 | Mexico | Details |
| Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu ( Site 2009) | RECRUITING | Torun | Kujawsko-pomorskie | 87-100 | Poland | Details |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier | RECRUITING | Warszawa | Mazowieckie | 02-781 | Poland | Details |
| Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 2001) | RECRUITING | Przemysl | Podkarpackie | 37-700 | Poland | Details |
| Narodowy Instytut Onkologii - Oddzial w Gliwicach-II Klinika Radioterapi i Chemioterapii ( Site 2002 | RECRUITING | Gliwice | Slaskie | 44-102 | Poland | Details |
| Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej ( Site 2005) | RECRUITING | Kielce | Swietokrzyskie | 25-734 | Poland | Details |
| HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Sit | RECRUITING | Barcelona | Cataluna | 08036 | Spain | Details |
| Hospital Insular de Gran Canaria-Oncology ( Site 2305) | RECRUITING | Las Palmas de Gran Canaria | Las Palmas | 35016 | Spain | Details |
| HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 2303) | RECRUITING | Madrid | Madrid, Comunidad De | 28009 | Spain | Details |
| HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 2301) | RECRUITING | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details |
| H.R.U Málaga - Hospital General-Oncology ( Site 2302) | RECRUITING | Málaga | Malaga | 29011 | Spain | Details |
| Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2300) | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Clinica Universidad de Navarra-Medical Oncology ( Site 2306) | RECRUITING | Madrid | 28027 | Spain | Details | |
| Changhua Christian Hospital ( Site 3908) | RECRUITING | Changhua County | Changhua | 50006 | Taiwan | Details |
| Chang Gung Memorial Hospital at Kaohsiung ( Site 3906) | RECRUITING | Kaohsiung Niao Sung Dist | Kaohsiung | 83301 | Taiwan | Details |
| Chi Mei Medical Center ( Site 3910) | RECRUITING | Tainan City | Tainan | 71004 | Taiwan | Details |
| National Taiwan University Cancer Center (NTUCC) ( Site 3903) | RECRUITING | Taipei City | Taipei | 106 | Taiwan | Details |
| National Taiwan University Hospital - Hsinchu branch ( Site 3907) | RECRUITING | Hsinchu | 300 | Taiwan | Details | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 3912) | RECRUITING | Kaohsiung | 807 | Taiwan | Details | |
| E-Da hospital ( Site 3911) | RECRUITING | Kaohsiung | 82445 | Taiwan | Details | |
| National Cheng Kung University Hospital ( Site 3909) | RECRUITING | Tainan | 704 | Taiwan | Details | |
| National Taiwan University Hospital-Oncology ( Site 3904) | RECRUITING | Taipei | 10002 | Taiwan | Details | |
| Mackay Memorial Hospital-Chest Medicine ( Site 3902) | RECRUITING | Taipei | 10449 | Taiwan | Details | |
| Taipei Medical University Hospital ( Site 3900) | RECRUITING | Taipei | 110301 | Taiwan | Details | |
| Faculty of Medicine Siriraj Hospital ( Site 4000) | RECRUITING | Bangkok | Krung Thep Maha Nakhon | 10700 | Thailand | Details |
| Songklanagarind hospital ( Site 4001) | RECRUITING | HatYai | Songkhla | 90110 | Thailand | Details |
| Maharaj Nakorn Chiang Mai Hospital ( Site 4003) | RECRUITING | Chiang Mai | 50200 | Thailand | Details | |
| Faculty of Medicine - Khon Kaen University ( Site 4004) | RECRUITING | Khon Kaen | 40002 | Thailand | Details | |
| Medipol Mega Universite Hastanesi-oncology ( Site 2505) | RECRUITING | Stanbul | Istanbul | 34214 | Turkey | Details |
| Hacettepe Universite Hastaneleri-oncology hospital ( Site 2500) | RECRUITING | Ankara | 06230 | Turkey | Details | |
| Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 2501) | RECRUITING | Ankara | 06800 | Turkey | Details | |
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2502) | RECRUITING | Istanbul | 34722 | Turkey | Details | |
| ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 2606) | RECRUITING | London | Kensington And Chelsea | SW3 6JJ | United Kingdom | Details |
| St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 2600) | RECRUITING | London | London, City Of | EC1A 7BE | United Kingdom | Details |
| Guy's & St Thomas' NHS Foundation Trust-Oncology & Haematology Clinical Trials ( Site 2603) | RECRUITING | London | London, City Of | SE1 9RT | United Kingdom | Details |
| Royal Marsden Hospital (Sutton) ( Site 2605) | RECRUITING | London | Sutton | SM2 5PT | United Kingdom | Details |
| The Clatterbridge Cancer Centre ( Site 2602) | RECRUITING | Wirral | CH63 4JY | United Kingdom | Details | |
| Hanoi Oncology Hospital ( Site 4102) | RECRUITING | Hanoi | Ha Noi | 100000 | Vietnam | Details |
| K Hospital - National Cancer Hospital ( Site 4105) | RECRUITING | Hanoi | Ha Noi | 100000 | Vietnam | Details |
| National Lung Hospital-Oncology Department ( Site 4104) | RECRUITING | Hanoi | Ha Noi | 100000 | Vietnam | Details |