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| NCT ID | NCT06252649 |
| Title | Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naive Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation (CodeBreaK 301) |
| Acronym | CodeBreaK 301 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Amgen |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | ROU | ITA | HUN | GRC | FRA | EST | ESP | DNK | DEU | CZE | CHE | BRA | BGR | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Ironwood Cancer and Research Centers Scottsdale | RECRUITING | Chandler | Arizona | 85224 | United States | Details |
| Providence Saint Jude Medical Center | RECRUITING | Fullerton | California | 92835 | United States | Details |
| Cancer and Blood Specialty Clinic | RECRUITING | Los Alamitos | California | 90720 | United States | Details |
| California Research Institute | RECRUITING | Los Angeles | California | 90027 | United States | Details |
| Norwalk Hospital | RECRUITING | Norwalk | Connecticut | 06856 | United States | Details |
| Cancer Specialists of North Florida | RECRUITING | Jacksonville | Florida | 32256 | United States | Details |
| D and H Cancer Research Center | RECRUITING | Margate | Florida | 33063 | United States | Details |
| Mid Florida Hematology and Oncology Centers PA | RECRUITING | Orange City | Florida | 32763 | United States | Details |
| Boca Raton Clinical Research Medical Center Inc | RECRUITING | Plantation | Florida | 33322 | United States | Details |
| Georgia Cancer Specialists | RECRUITING | Atlanta | Georgia | 30342 | United States | Details |
| Hope and Healing Cancer Services | RECRUITING | Hinsdale | Illinois | 60521 | United States | Details |
| Orchard Healthcare Research Inc | RECRUITING | Skokie | Illinois | 60076 | United States | Details |
| Pikeville Medical Center | RECRUITING | Pikeville | Kentucky | 41501 | United States | Details |
| Cancer and Hematology Centers of Western Michigan | RECRUITING | Grand Rapids | Michigan | 49503 | United States | Details |
| Saint Louis Cancer Care West County | RECRUITING | Bridgeton | Missouri | 63044 | United States | Details |
| Minniti Center for Medical Oncology and Hematology | RECRUITING | Mickleton | New Jersey | 08056 | United States | Details |
| Duke Cancer Center | RECRUITING | Durham | North Carolina | 27710 | United States | Details |
| FirstHealth Cancer Center | RECRUITING | Pinehurst | North Carolina | 28374 | United States | Details |
| Thomas Jefferson University | RECRUITING | Philadelphia | Pennsylvania | 19107 | United States | Details |
| Carolina Blood and Cancer Care | RECRUITING | Rock Hill | South Carolina | 29732 | United States | Details |
| Hospital Universitario Fundacion Favaloro | RECRUITING | Caba | Buenos Aires | C1093AAS | Argentina | Details |
| Instituto Argentino de Diagnóstico y Tratamiento | RECRUITING | Caba | Buenos Aires | C1093AAS | Argentina | Details |
| Investigaciones Clinicas Moleculares - Centro de Endocrinologia y Diabetes Dr Raul Gutman SRL | RECRUITING | Caba | Buenos Aires | C1425BGH | Argentina | Details |
| Cemic | RECRUITING | Ciudad Autonoma de Buenos Aires | Buenos Aires | C1431FWO | Argentina | Details |
| Sanatorio Británico de Rosario | RECRUITING | La Plata | Buenos Aires | 1900 | Argentina | Details |
| Instituto de Investigaciones clinicas de Mar del Plata | RECRUITING | Mar Del Plata | Buenos Aires | B7600FZO | Argentina | Details |
| Sanatorio Allende | RECRUITING | Cordoba | Córdoba | X5000JHQ | Argentina | Details |
| Clinica Universitaria Privada Reina Fabiola | RECRUITING | Cordoba | Córdoba | X5004FHP | Argentina | Details |
| Clinica Viedma | RECRUITING | Viedma | Río Negro | 8500 | Argentina | Details |
| Exelsus Oncologia Clinica | RECRUITING | San Miguel de Tucuman | Tucuman | 4000 | Argentina | Details |
| Hospital Britanico de Buenos Aires | RECRUITING | Buenos Aires | C1280AEB | Argentina | Details | |
| Centro Oncologico Riojano Integral | RECRUITING | La Rioja | F5300COE | Argentina | Details | |
| Chris OBrien Lifehouse | RECRUITING | Camperdown | New South Wales | 2050 | Australia | Details |
| Toowoomba Hospital | RECRUITING | Toowoomba | Queensland | 4350 | Australia | Details |
| Flinders Medical Centre | RECRUITING | Bedford Park | South Australia | 5042 | Australia | Details |
| The Queen Elizabeth Hospital | RECRUITING | Woodville South | South Australia | 5011 | Australia | Details |
| Austin Health, Austin Hospital | RECRUITING | Heidelberg | Victoria | 3084 | Australia | Details |
| Ordensklinikum Linz Barmherzige Schwestern | RECRUITING | Linz | 4010 | Austria | Details | |
| Landeskrankenhaus Feldkirch | RECRUITING | Rankweil | 6830 | Austria | Details | |
| Institut Jules Bordet | RECRUITING | Brussels | B-1070 | Belgium | Details | |
| Universitair Ziekenhuis Gent | RECRUITING | Gent | 9000 | Belgium | Details | |
| Algemeen Ziekenhuis Sint-Maarten | RECRUITING | Mechelen | 2800 | Belgium | Details | |
| AZ Delta Campus Rumbeke | RECRUITING | Roeselare | 8800 | Belgium | Details | |
| Hospital Sirio Libanes | RECRUITING | Brasilia | Distrito Federal | 70200-730 | Brazil | Details |
| Hospital Evangelico de Cachoeiro de Itapemirim | RECRUITING | Cachoeiro de Itapemirim | Espírito Santo | 29308-020 | Brazil | Details |
| Vencer e Oncoclinica | RECRUITING | Teresina | Piauí | 64049-200 | Brazil | Details |
| Liga Norte-Riograndense Contra O Cancer | RECRUITING | Natal | Rio Grande Do Norte | 59075-740 | Brazil | Details |
| Oncosite Centro de Pesquisa Clinica Em Oncologia Ltda | RECRUITING | Ijui | Rio Grande Do Sul | 98700-000 | Brazil | Details |
| Irmandade da Santa Casa de Misericordia de Porto Alegre | RECRUITING | Porto Alegre | Rio Grande Do Sul | 90050-170 | Brazil | Details |
| Associação Hospitalar Moinhos de Vento | RECRUITING | Porto Alegre | Rio Grande Do Sul | 90560-030 | Brazil | Details |
| Clinica de Neoplasias Litoral | RECRUITING | Itajai | Santa Catarina | 88301-220 | Brazil | Details |
| Fundacao Pio 12 Hospital de Amor de Barretos | RECRUITING | Barretos | São Paulo | 14784-400 | Brazil | Details |
| Oncoclinicas Belo Horizonte | RECRUITING | Barretos | São Paulo | 14784-400 | Brazil | Details |
| Fundacao Antonio Prudente AC Camargo Cancer Center | RECRUITING | Sao Paulo | São Paulo | 01246-000 | Brazil | Details |
| Oncologia Rede D Or | RECRUITING | Sao Paulo | São Paulo | 04501-000 | Brazil | Details |
| Hospital de Base de Sao Jose do Rio Preto | RECRUITING | São José do Rio Preto | São Paulo | 15090-000 | Brazil | Details |
| Oncoclinicas Rio de Janeiro S A | RECRUITING | Rio de Janeiro | 22250-905 | Brazil | Details | |
| Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira Icesp | RECRUITING | São Paulo | 01246-000 | Brazil | Details | |
| Instituto Brasileiro de Controle do Cancer Ibcc | RECRUITING | São Paulo | 04014-002 | Brazil | Details | |
| Specialized Hospital for Active Treatment of Oncology - Haskovo EOOD | RECRUITING | Haskovo | 6300 | Bulgaria | Details | |
| Multiprofile Hospital for Active Treatment Central Onco Hospital OOD | RECRUITING | Plovdiv | 4000 | Bulgaria | Details | |
| Complex Oncology Center Plovdiv EOOD | RECRUITING | Plovdiv | 4004 | Bulgaria | Details | |
| Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia | RECRUITING | Sofia | 1606 | Bulgaria | Details | |
| Multiprofile Hospital for Active Treatment Serdika EOOD | RECRUITING | Sofia | 1632 | Bulgaria | Details | |
| James Lind Centro de Investigacion del Cancer | RECRUITING | Temuco | Cautín | 4800827 | Chile | Details |
| Centro de oncologia de precision Spa | RECRUITING | Las Condes | Santiago | Chile | Details | |
| Clinica Redsalud Vitacura, Instituto del Cancer | RECRUITING | Vitacura | Santiago | 7650018 | Chile | Details |
| Fundacion Arturo Lopez Perez | RECRUITING | Santiago | 7500921 | Chile | Details | |
| Institucion Prestadora de Servicios de Salud Sociedad Médica Rionegro SA Somer SA | RECRUITING | Rionegro | Antioquia | 054040 | Colombia | Details |
| Instituto Nacional de Cancerologia | RECRUITING | Bogota | Cundinamarca | 111711 | Colombia | Details |
| Centro de Tratamiento e Investigación sobre Cancer Luis Carlos Sarmiento Angulo Ctic | RECRUITING | Bogotá | Cundinamarca | 110131 | Colombia | Details |
| Instituto Medico de Alta Tecnologia sas - Imat sas | RECRUITING | Montería | Córdoba | 230018 | Colombia | Details |
| Fundacion Oftalmologica de Santander - Foscal | RECRUITING | Floridablanca | Santander | 681004 | Colombia | Details |
| Masarykuv onkologicky ustav | RECRUITING | Brno | 656 53 | Czechia | Details | |
| Fakultni nemocnice Olomouc | RECRUITING | Olomouc | 779 00 | Czechia | Details | |
| Fakultni nemocnice Kralovske Vinohrady | RECRUITING | Praha 10 | 100 34 | Czechia | Details | |
| Fakultni nemocnice v Motole | RECRUITING | Praha 5 | 150 06 | Czechia | Details | |
| Aalborg Sygehus | RECRUITING | Aalborg | 9000 | Denmark | Details | |
| Aarhus University Hospital | RECRUITING | Aarhus N | 8200 | Denmark | Details | |
| Rigshospitalet | RECRUITING | Copenhagen | 2100 | Denmark | Details | |
| Odense University Hospital | RECRUITING | Odense C | 5000 | Denmark | Details | |
| North Estonia Medical Centre Foundation | RECRUITING | Tallinn | 13419 | Estonia | Details | |
| Centre Hospitalier Universitaire de Clermont Ferrand - Hopital Estaing | RECRUITING | Clermont-Ferrand cedex 1 | 63003 | France | Details | |
| Centre Hospitalier Universitaire de Poitiers | RECRUITING | Poitiers Cedex | 86021 | France | Details | |
| Charite - Universitaetsmedizin Berlin, Campus Virchow | RECRUITING | Berlin | 13353 | Germany | Details | |
| Klinikum Chemnitz gGmbH | RECRUITING | Chemnitz | 09116 | Germany | Details | |
| Universitaetsklinikum Dresden | RECRUITING | Dresden | 01307 | Germany | Details | |
| Universitaetsklinikum Essen | RECRUITING | Essen | 45147 | Germany | Details | |
| UCT Universitaeres Zentrum fuer Tumorerkrankungen Frankfurt | RECRUITING | Frankfurt am Main | 60488 | Germany | Details | |
| Haematologisch Onkologische Praxis Eppendorf | RECRUITING | Hamburg | 20246 | Germany | Details | |
| Regional Kliniken Holding Klinikum Ludwigsburg | RECRUITING | Ludwigsburg | 71640 | Germany | Details | |
| Klinikum der LMU Muenchen | RECRUITING | Muenchen | 81377 | Germany | Details | |
| Universitaetsklinikum Ulm | RECRUITING | Ulm | 89081 | Germany | Details | |
| Klinikum der Stadt Wolfsburg | RECRUITING | Wolfsburg | 38440 | Germany | Details | |
| Agios Savvas Anticancer Hospital | RECRUITING | Athens | 11522 | Greece | Details | |
| Metropolitan Hospital | RECRUITING | Athens | 18547 | Greece | Details | |
| Bioclinic of Thessaloniki | RECRUITING | Thessaloniki | 54622 | Greece | Details | |
| Agios Loukas Clinic | RECRUITING | Thessaloniki | 55236 | Greece | Details | |
| Saint Lukes Hospital SA | RECRUITING | Thessaloniki | 55236 | Greece | Details | |
| European Interbalkan Medical Center | RECRUITING | Thessaloniki | 57001 | Greece | Details | |
| Queen Mary Hospital, The University of Hong Kong | RECRUITING | Hong Kong | Hong Kong | Details | ||
| Princess Margaret Hospital | RECRUITING | Kowloon | Hong Kong | Details | ||
| Debreceni Egyetem Klinikai Kozpont | RECRUITING | Debrecen | 4032 | Hungary | Details | |
| Bekes Varmegyei Kozponti Korhaz Pandy Kalman Tagkorhaz | RECRUITING | Gyula | 5700 | Hungary | Details | |
| Somogy Varmegyei Kaposi Mor Oktato Korhaz | RECRUITING | Kaposvar | 7400 | Hungary | Details | |
| Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz Nyiregyhazi Josa Andras Tagkorhaz | RECRUITING | Nyiregyhaza | 4400 | Hungary | Details | |
| Jasz-Nagykun-Szolnok Varmegyei Hetenyi Geza Korhaz-Rendelointezet | RECRUITING | Szolnok | 5000 | Hungary | Details | |
| Istituto Ospedaliero Fondazione Poliambulanza | RECRUITING | Brescia | 25124 | Italy | Details | |
| Aichi Cancer Center | RECRUITING | Nagoya-shi | Aichi | 464-8681 | Japan | Details |
| Chiba Cancer Center | RECRUITING | Chiba-shi | Chiba | 260-8717 | Japan | Details |
| National Cancer Center Hospital East | RECRUITING | Kashiwa-shi | Chiba | 277-8577 | Japan | Details |
| National Hospital Organization Shikoku Cancer Center | RECRUITING | Matsuyama-shi | Ehime | 791-0280 | Japan | Details |
| National Hospital Organization Kyushu Cancer Center | RECRUITING | Fukuoka-shi | Fukuoka | 811-1395 | Japan | Details |
| Hokkaido University Hospital | RECRUITING | Sapporo | Hokkaido | 060-8648 | Japan | Details |
| Hyogo Cancer Center | RECRUITING | Akashi-shi | Hyogo | 673-8558 | Japan | Details |
| St Marianna University Hospital | RECRUITING | Kawasaki-shi | Kanagawa | 216-8511 | Japan | Details |
| Yokohama City University Medical Center | RECRUITING | Yokohama-shi | Kanagawa | 232-0024 | Japan | Details |
| Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center | RECRUITING | Yokohama-shi | Kanagawa | 241-8515 | Japan | Details |
| Niigata Cancer Center Hospital | RECRUITING | Niigata-shi | Niigata | 951-8566 | Japan | Details |
| Kansai Medical University Hospital | RECRUITING | Hirakata-shi | Osaka | 573-1191 | Japan | Details |
| National Hospital Organization Osaka National Hospital | RECRUITING | Osaka-shi | Osaka | 540-0006 | Japan | Details |
| Osaka University Hospital | RECRUITING | Suita-shi | Osaka | 565-0871 | Japan | Details |
| Saitama Cancer Center | RECRUITING | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details |
| Shizuoka Cancer Center | RECRUITING | Sunto-gun | Shizuoka | 411-8777 | Japan | Details |
| Tokushima University Hospital | RECRUITING | Tokushima-shi | Tokushima | 770-8503 | Japan | Details |
| National Cancer Center Hospital | RECRUITING | Chuo-ku | Tokyo | 104-0045 | Japan | Details |
| The Cancer Institute Hospital of Japanese Foundation for Cancer Research | RECRUITING | Koto-ku | Tokyo | 135-8550 | Japan | Details |
| National Cancer Center | RECRUITING | Goyang-si Gyeonggi-do | 10408 | Korea, Republic of | Details | |
| Korea University Anam Hospital | RECRUITING | Seoul | 02841 | Korea, Republic of | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Severance Hospital Yonsei University Health System | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| The Catholic University of Korea Seoul St Marys Hospital | RECRUITING | Seoul | 06591 | Korea, Republic of | Details | |
| Korea University Guro Hospital | RECRUITING | Seoul | 08308 | Korea, Republic of | Details | |
| Asan Medical Center | RECRUITING | Seoul | 138-736 | Korea, Republic of | Details | |
| Centro Especializado en Investigacion y Tratamiento Oncologicos SC | RECRUITING | Benito Juárez | Distrito Federal | 03104 | Mexico | Details |
| Health Pharma Professional Research SA de CV | RECRUITING | Mexico City | Distrito Federal | 03100 | Mexico | Details |
| Hospital da Luz, SA | RECRUITING | Lisboa | 1500-650 | Portugal | Details | |
| Institutul Clinic Fundeni | RECRUITING | Bucharest | 022328 | Romania | Details | |
| Centrul de Oncologie Sf Nectarie SRL | RECRUITING | Craiova | 200542 | Romania | Details | |
| Institutul Regional de Oncologie Iasi | RECRUITING | Iasi | 700483 | Romania | Details | |
| SC Oncomed SRL | RECRUITING | Timisoara | 300239 | Romania | Details | |
| Hospital Universitario Reina Sofia | RECRUITING | Cordoba | Andalucía | 14004 | Spain | Details |
| Hospital Universitario Virgen de las Nieves | RECRUITING | Granada | Andalucía | 18014 | Spain | Details |
| Hospital Regional Universitario de Malaga | RECRUITING | Malaga | Andalucía | 29010 | Spain | Details |
| Hospital Universitario Virgen del Rocio | RECRUITING | Sevilla | Andalucía | 41013 | Spain | Details |
| Hospital Universitario Marques de Valdecilla | RECRUITING | Santander | Cantabria | 39008 | Spain | Details |
| Hospital Universitario de Burgos | RECRUITING | Burgos | Castilla León | 09006 | Spain | Details |
| Hospital Universitari Vall d Hebron | RECRUITING | Barcelona | Cataluña | 08035 | Spain | Details |
| Hospital de la Santa Creu i Sant Pau | RECRUITING | Barcelona | Cataluña | 08041 | Spain | Details |
| Hospital General Universitario de Elche | RECRUITING | Elche | Comunidad Valenciana | 03203 | Spain | Details |
| Hospital General Universitario de Valencia | RECRUITING | Valencia | Comunidad Valenciana | 46014 | Spain | Details |
| Hospital General Universitario Gregorio Maranon | RECRUITING | Madrid | 28009 | Spain | Details | |
| Hospital Universitario 12 de Octubre | RECRUITING | Madrid | 28041 | Spain | Details | |
| Hospital Universitario La Paz | RECRUITING | Madrid | 28046 | Spain | Details | |
| Södersjukhuset, onkologikliniken | RECRUITING | Stockholm | 118 83 | Sweden | Details | |
| Universitaetsspital Zuerich | RECRUITING | Zuerich | 8091 | Switzerland | Details | |
| China Medical University Hospital | RECRUITING | Taichung | 40447 | Taiwan | Details | |
| Taichung Veterans General Hospital | RECRUITING | Taichung | 40705 | Taiwan | Details | |
| Taipei Veterans General Hospital | RECRUITING | Taipei | 11217 | Taiwan | Details | |
| Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation | RECRUITING | Taoyuan | 33305 | Taiwan | Details | |
| Siriraj Hospital | RECRUITING | Bangkok | 10700 | Thailand | Details | |
| Adana Sehir Egitim ve Arastirma Hastanesi | RECRUITING | Adana | 01370 | Turkey | Details | |
| Hacettepe Universitesi Tip Fakultesi Hastanesi | RECRUITING | Ankara | 06230 | Turkey | Details | |
| Gazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi | RECRUITING | Ankara | 06560 | Turkey | Details | |
| Ankara Universitesi Tip Fakultesi Hastanesi | RECRUITING | Ankara | 06590 | Turkey | Details | |
| Ankara Bilkent Sehir Hastanesi | RECRUITING | Ankara | 06800 | Turkey | Details | |
| Trakya Universitesi Saglik Arastirma ve Uygulama Merkezi | RECRUITING | Edirne | 22030 | Turkey | Details | |
| Bezmialem Vakif Universitesi Hastanesi | RECRUITING | Istanbul | 34093 | Turkey | Details | |
| Bagcilar Medipol Mega Universite Hastanesi | RECRUITING | Istanbul | 34214 | Turkey | Details | |
| Acibadem Altunizade Hastanesi | RECRUITING | Istanbul | 34662 | Turkey | Details | |
| Ege Universitesi Tip Fakultesi Hastanesi | RECRUITING | Izmir | 35100 | Turkey | Details | |
| Necmettin Erbakan Universitesi Tip Fakultesi Hastanesi | RECRUITING | Konya | 42080 | Turkey | Details | |
| Inonu Universitesi Turgut Ozal Tip Merkezi | RECRUITING | Malatya | 44280 | Turkey | Details |