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| NCT ID | NCT06312176 |
| Title | A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010) |
| Acronym | MK-2870-010 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ROU | POL | NZL | NLD | ITA | ISR | HUN | GRC | GBR | FRA | ESP | CHE | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Providence Medical Foundation-Oncology ( Site 0020) | RECRUITING | Fullerton | California | 92835 | United States | Details |
| Yale Cancer Center ( Site 0060) | RECRUITING | New Haven | Connecticut | 06510 | United States | Details |
| AdventHealth Altamonte Springs ( Site 0021) | RECRUITING | Altamonte Springs | Florida | 32701 | United States | Details |
| Orlando Health Cancer Institute ( Site 0011) | RECRUITING | Orlando | Florida | 32806 | United States | Details |
| Archbold Memorial Hospital-Lewis Hall Singletary Oncology Center ( Site 0032) | RECRUITING | Thomasville | Georgia | 31792 | United States | Details |
| Mary Bird Perkins Cancer Center-Breast & GYN Pavilion ( Site 0042) | RECRUITING | Baton Rouge | Louisiana | 70817 | United States | Details |
| Mercy Medical Center - Baltimore-Medical Oncology and Hematology ( Site 0028) | RECRUITING | Baltimore | Maryland | 21202 | United States | Details |
| Hematology Oncology Associates of Rockland ( Site 0054) | RECRUITING | Nyack | New York | 10960 | United States | Details |
| Stony Brook University-Cancer Center ( Site 0034) | RECRUITING | Stony Brook | New York | 11794 | United States | Details |
| Providence Portland Medical Center ( Site 0044) | RECRUITING | Portland | Oregon | 97213 | United States | Details |
| Providence St. Vincent Medical Center ( Site 0081) | RECRUITING | Portland | Oregon | 97225 | United States | Details |
| The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( | RECRUITING | Tyler | Texas | 75701 | United States | Details |
| Instituto Alexander Fleming-Alexander Fleming ( Site 0382) | RECRUITING | Ciudad Autónoma de Buenos Aires | Caba | 1426 | Argentina | Details |
| Fundacion Estudios Clinicos-Oncology ( Site 0384) | RECRUITING | Rosario | Santa Fe | S2000DEJ | Argentina | Details |
| Hospital Aleman-Oncology ( Site 0386) | RECRUITING | Buenos Aires | C1118AAT | Argentina | Details | |
| Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 0383) | RECRUITING | Buenos Aires | C1431FWO | Argentina | Details | |
| Hospital Italiano de Córdoba ( Site 0385) | RECRUITING | Cordoba | X5004BAL | Argentina | Details | |
| Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0387) | RECRUITING | La Rioja | F5300COE | Argentina | Details | |
| Macquarie University-MQ Health Clinical Trials Unit ( Site 2002) | RECRUITING | Macquarie University | New South Wales | 2109 | Australia | Details |
| Westmead Hospital-Westmead Breast Cancer Institute ( Site 2000) | RECRUITING | Westmead | New South Wales | 2145 | Australia | Details |
| Frankston Hospital-Oncology and Haematology ( Site 2003) | RECRUITING | Frankston | Victoria | 3199 | Australia | Details |
| Fiona Stanley Hospital-Medical Oncology ( Site 2004) | RECRUITING | Murdoch | Western Australia | 6150 | Australia | Details |
| AZ Maria Middelares-IKG ( Site 1106) | RECRUITING | Gent | Oost-Vlaanderen | 9000 | Belgium | Details |
| Oncoclínica Oncologistas Associados-Clinical Research ( Site 0407) | RECRUITING | Teresina | Piaui | 64049-200 | Brazil | Details |
| Hospital Moinhos de Vento ( Site 0403) | RECRUITING | Porto Alegre | Rio Grande Do Sul | 90035-001 | Brazil | Details |
| Hospital do Câncer Mãe de Deus ( Site 0404) | RECRUITING | Porto Alegre | Rio Grande Do Sul | 90110-270 | Brazil | Details |
| Instituto de Oncologia Saint Gallen ( Site 0412) | RECRUITING | Santa Cruz do Sul | Rio Grande Do Sul | 96830-180 | Brazil | Details |
| Instituto do Câncer Brasil - Unidade Taubaté ( Site 0408) | RECRUITING | Taubaté | Sao Paulo | 12030-200 | Brazil | Details |
| IBCC - Núcleo de Pesquisa e Ensino ( Site 0401) | RECRUITING | Sao Paulo | 04014-002 | Brazil | Details | |
| CIUSSS de l'Est-de-l'Île-de-Montréal ( Site 0301) | RECRUITING | Montreal | Quebec | H1T 2M4 | Canada | Details |
| Jewish General Hospital ( Site 0303) | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| FALP-UIDO ( Site 0451) | RECRUITING | Santiago | Region M. De Santiago | 7500921 | Chile | Details |
| Oncovida ( Site 0453) | RECRUITING | Santiago | Region M. De Santiago | 7510032 | Chile | Details |
| Clínica RedSalud Vitacura ( Site 0455) | RECRUITING | Santiago | Region M. De Santiago | 7650018 | Chile | Details |
| Pontificia Universidad Catolica de Chile-Centro del Cáncer ( Site 0454) | RECRUITING | Santiago | Region M. De Santiago | 8330032 | Chile | Details |
| Bradfordhill ( Site 0452) | RECRUITING | Santiago | Region M. De Santiago | 8420383 | Chile | Details |
| Bradford Hill Norte ( Site 0456) | RECRUITING | Antofagasta | 1263521 | Chile | Details | |
| Fundacion Colombiana de Cancerología Clinica Vida ( Site 0506) | RECRUITING | Medellín | Antioquia | 050030 | Colombia | Details |
| Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501) | RECRUITING | Valledupar | Cesar | 200001 | Colombia | Details |
| Oncomédica S.A.S ( Site 0502) | RECRUITING | Monteria | Cordoba | 230002 | Colombia | Details |
| FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Sit | RECRUITING | Bogota | Distrito Capital De Bogota | 110131 | Colombia | Details |
| Fundación Valle del Lili ( Site 0508) | RECRUITING | Cali | Valle Del Cauca | 760032 | Colombia | Details |
| CIMCA ( Site 0551) | RECRUITING | San José | San Jose | 10103 | Costa Rica | Details |
| Hospital Metropolitano - Sede Lindora ( Site 0550) | RECRUITING | Santa Ana | San Jose | 10903 | Costa Rica | Details |
| ICIMED ( Site 0552) | RECRUITING | San Jose | 10108 | Costa Rica | Details | |
| Centre François Baclesse ( Site 1250) | RECRUITING | Caen | Calvados | 14076 | France | Details |
| Centre de Cancérologie du Grand Montpellier ( Site 1244) | RECRUITING | Montpellier | Languedoc-Roussillon | 34070 | France | Details |
| Hôpital privé du Confluent SAS-Service d'oncologie médicale ( Site 1242) | RECRUITING | Nantes | Loire-Atlantique | 44277 | France | Details |
| Pitie Salpetriere University Hospital ( Site 1249) | RECRUITING | Paris | Orne | 75013 | France | Details |
| Hopital Prive Jean Mermoz-Oncology ( Site 1246) | RECRUITING | Lyon | Rhone-Alpes | 69008 | France | Details |
| Institut Curie-Oncology medical Department ( Site 1240) | RECRUITING | Paris | 75248 | France | Details | |
| Errikos Dunant Hospital Center ( Site 1348) | RECRUITING | Athens | Attiki | 115 26 | Greece | Details |
| Agios Loukas Clinic ( Site 1347) | RECRUITING | Thessaloniki | Kentriki Makedonia | 552 36 | Greece | Details |
| University General Hospital of Larissa ( Site 1343) | RECRUITING | Larissa | Thessalia | 411 10 | Greece | Details |
| Queen Mary Hospital ( Site 2040) | RECRUITING | Hksar | Hong Kong | Details | ||
| Prince of Wales Hospital ( Site 2041) | RECRUITING | Shatin | Hong Kong | Details | ||
| Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterápiás Klinika ( Site 1379) | RECRUITING | Szeged | Csongrad | 6720 | Hungary | Details |
| Somogy Vármegyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1371) | RECRUITING | Kaposvár | Somogy | 7400 | Hungary | Details |
| Zala Vármegyei Szent Rafael Kórház-Onkológiai osztály ( Site 1372) | RECRUITING | Zalaegerszeg | Zala | 8900 | Hungary | Details |
| Budapesti Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 1373) | RECRUITING | Budapest | 1145 | Hungary | Details | |
| Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1375) | RECRUITING | Debrecen | 4032 | Hungary | Details | |
| Rambam Health Care Campus-Oncology Division ( Site 1452) | RECRUITING | Haifa | 3109601 | Israel | Details | |
| Hadassah Medical Center ( Site 1451) | RECRUITING | Jerusalem | 9112001 | Israel | Details | |
| Rabin Medical Center ( Site 1453) | RECRUITING | Petah Tikva | 4941492 | Israel | Details | |
| Sheba Medical Center ( Site 1450) | RECRUITING | Ramat Gan | 5265601 | Israel | Details | |
| CRO-IRCCS ( Site 1478) | RECRUITING | Aviano | Friuli-Venezia Giulia | 33081 | Italy | Details |
| Istituto Europeo di Oncologia IRCCS-Divisione di Senologia Medica ( Site 1475) | RECRUITING | Milano | Lombardia | 20141 | Italy | Details |
| Istituto Clinico Humanitas ( Site 1476) | RECRUITING | Rozzano | Milano | 20089 | Italy | Details |
| IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1474) | RECRUITING | Bologna | 40138 | Italy | Details | |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( | RECRUITING | Roma | 00168 | Italy | Details | |
| Seoul National University Hospital-Internal Medicine ( Site 2353) | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System-Medical oncology ( Site 2350) | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Asan Medical Center-Department of Oncology ( Site 2352) | RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| Samsung Medical Center-Division of Hematology/Oncology ( Site 2351) | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Hospital Sultan Ismail ( Site 2153) | RECRUITING | Johor Bahru | Johor | 81100 | Malaysia | Details |
| Sarawak General Hospital ( Site 2154) | RECRUITING | Kuching | Sarawak | 93586 | Malaysia | Details |
| Pantai Hospital Kuala Lumpur ( Site 2151) | RECRUITING | Kuala Lumpur | 59100 | Malaysia | Details | |
| Health Pharma Professional Research S.A. de C.V: ( Site 0598) | RECRUITING | Ciudad de México | Distrito Federal | 03100 | Mexico | Details |
| Grupo Médico ASSET-Clinical Research ( Site 0596) | RECRUITING | Mexico City | Distrito Federal | 03100 | Mexico | Details |
| CIO - Centro de Inmuno-Oncología de Occidente ( Site 0592) | RECRUITING | Guadalajara | Jalisco | 44630 | Mexico | Details |
| CENTRO MEDICO ZAMBRANO HELLION-Centro de Cáncer de Mama ( Site 0595) | RECRUITING | San Pedro Garza Garcia | Nuevo Leon | 66278 | Mexico | Details |
| Ziekenhuis Rijnstate-Rijnstate Centrum Oncologisch Onderzoek ( Site 1524) | RECRUITING | Arnhem | Gelderland | 6815 AD | Netherlands | Details |
| Maastricht UMC+-Medical Oncology ( Site 1522) | RECRUITING | Maastricht | Limburg | 6229 HX | Netherlands | Details |
| Amphia Ziekenhuis, locatie Breda Molengracht-oncologie ( Site 1523) | RECRUITING | Breda | Noord-Brabant | 4800 RK | Netherlands | Details |
| Catharina Ziekenhuis ( Site 1526) | RECRUITING | Eindhoven | Noord-Brabant | 5623 EJ | Netherlands | Details |
| Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)-medical oncology ( Site 1520) | RECRUITING | Amsterdam | Noord-Holland | 1066 CX | Netherlands | Details |
| Meander Medisch Centrum ( Site 1521) | RECRUITING | Amersfoort | Utrecht | 3813TZ | Netherlands | Details |
| Auckland City Hospital-Cancer & Blood Research ( Site 2031) | RECRUITING | Auckland | 1023 | New Zealand | Details | |
| Clinica Vallesur - AUNA ( Site 0652) | RECRUITING | Arequipa | Ariqipa | 04001 | Peru | Details |
| Hospital Militar Central Luis Arias Schereiber ( Site 0651) | RECRUITING | Jesús María | Lima | 18 | Peru | Details |
| Oncosalud ( Site 0650) | RECRUITING | Lima | Muni Metro De Lima | 15036 | Peru | Details |
| IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0653) | RECRUITING | Lima | 15036 | Peru | Details | |
| Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1582) | RECRUITING | Bydgoszcz | Kujawsko-pomorskie | 85-796 | Poland | Details |
| Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1584) | RECRUITING | Siedlce | Mazowieckie | 08-110 | Poland | Details |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Piersi i Chirurgii ( | RECRUITING | Warszawa | Mazowieckie | 02-781 | Poland | Details |
| Mazowiecki Szpital Onkologiczny ( Site 1581) | RECRUITING | Wieliszew | Mazowieckie | 05-135 | Poland | Details |
| Mrukmed-Mrukmed ( Site 1592) | RECRUITING | Rzeszow | Podkarpackie | 35-021 | Poland | Details |
| Bialostockie Centrum Onkologii ( Site 1585) | RECRUITING | Bialystok | Podlaskie | 15-027 | Poland | Details |
| Szpitale Pomorskie Sp. z o. o.-Oddział Onkologii Klinicznej ( Site 1593) | RECRUITING | Gdynia | Pomorskie | 81-519 | Poland | Details |
| Narodowy Instytut Onkologii - Oddzial w Gliwicach-Centrum Diagnostyki i Leczenia Chorob Piersi ( Sit | RECRUITING | Gliwice | Slaskie | 44-102 | Poland | Details |
| Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch | RECRUITING | Kielce | Swietokrzyskie | 25-734 | Poland | Details |
| Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1583) | RECRUITING | Koszalin | Zachodniopomorskie | 75-581 | Poland | Details |
| Unidade Local de Saude Amadora/Sintra - Hospital Prof Dr Fernando Fonseca ( Site 1663) | RECRUITING | Lisbon | Lisboa | 2720-276 | Portugal | Details |
| Puerto Rico Medical Research Center LLC ( Site 0675) | RECRUITING | Hato Rey | 00917 | Puerto Rico | Details | |
| UPR Comprehensive Cancer Center-Comprehensive Cancer Center Hospital ( Site 0677) | RECRUITING | San Juan | 00935 | Puerto Rico | Details | |
| Spitalul Clinic Filantropia ( Site 1703) | RECRUITING | București | Bucuresti | 011171 | Romania | Details |
| SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 1702) | RECRUITING | Florești | Cluj | 407280 | Romania | Details |
| Centrul Medical Neolife- Baneasa ( Site 1704) | RECRUITING | Bucuresti | 077190 | Romania | Details | |
| Institutul Oncologic Cluj ( Site 1701) | RECRUITING | Cluj | 400015 | Romania | Details | |
| National University Hospital ( Site 2250) | RECRUITING | Singapore | Central Singapore | 119074 | Singapore | Details |
| HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1758) | RECRUITING | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details |
| HOSPITAL CLINICO DE VALENCIA-Oncology ( Site 1752) | RECRUITING | Valencia | Valenciana, Comunitat | 46010 | Spain | Details |
| Hospital Universitari Vall d'Hebron-Oncology ( Site 1750) | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Universitario Reina Sofia-Oncologia Medica ( Site 1754) | RECRUITING | Cordoba | 14004 | Spain | Details | |
| Hospital Beata María Ana-oncology ( Site 1755) | RECRUITING | Madrid | 28007 | Spain | Details | |
| HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 1756) | RECRUITING | Madrid | 28009 | Spain | Details | |
| Hospital Universitario Virgen Macarena ( Site 1757) | RECRUITING | Sevilla | 41009 | Spain | Details | |
| University Hospital Basel-Gynecology & Gynecologic Oncology ( Site 1844) | RECRUITING | Basel | Basel-Stadt | 4031 | Switzerland | Details |
| Spital Thun ( Site 1840) | RECRUITING | Thun | Berne | 3600 | Switzerland | Details |
| Brust-Zentrum ( Site 1841) | RECRUITING | Zürich | Zurich | 8008 | Switzerland | Details |
| Changhua Christian Hospital ( Site 2410) | RECRUITING | Changhua County | Changhua | 50006 | Taiwan | Details |
| Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 2413) | RECRUITING | Kaohsiung | 83301 | Taiwan | Details | |
| National Cheng Kung University Hospital-Surgery ( Site 2411) | RECRUITING | Tainan | 704 | Taiwan | Details | |
| National Taiwan University Hospital-Oncology ( Site 2415) | RECRUITING | Taipei | 10002 | Taiwan | Details | |
| Mackay Memorial Hospital ( Site 2412) | RECRUITING | Taipei | 10449 | Taiwan | Details | |
| Chang Gung Medical Foundation-Linkou Branch-General Surgery ( Site 2414) | RECRUITING | Taoyuan | 333 | Taiwan | Details | |
| The Royal Cornwall Hospital ( Site 1943) | RECRUITING | Truro | England | TR1 3LJ | United Kingdom | Details |
| St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1940) | RECRUITING | London | London, City Of | EC1A 7BE | United Kingdom | Details |
| University College London Hospital-Cancer Clinical Trials Unit ( Site 1942) | RECRUITING | London | London, City Of | NW1 2PG | United Kingdom | Details |
| City Hospital, Nottingham University Hospitals NHS Trust ( Site 1945) | RECRUITING | Nottingham | NG5 1PB | United Kingdom | Details |