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| NCT ID | NCT06346067 |
| Title | A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2) |
| Acronym | SEACRAFT-2 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Erasca, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | CZE | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alfred Hospital | RECRUITING | Melbourne | 3004 | Australia | Details | |
| APHP - Hopital Saint Louis | RECRUITING | Paris | 9001 | France | Details | |
| Assistance Publique Hopitaux de Marseille (AP-HM) - Hopital de la Timone | RECRUITING | Marseille | 13005 | France | Details | |
| Azienda Sanitaria Universitaria del Friuli Centrale | RECRUITING | Udine | 33100 | Italy | Details | |
| Barbara Ann Karmanos Cancer Institute | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Calvary Mater Newcastle | RECRUITING | Waratah | New South Wales | 2298 | Australia | Details |
| Centre Hospitalier du Mans | RECRUITING | Le Mans | 72000 | France | Details | |
| Centre Hospitalier Lyon-Sud | RECRUITING | Lyon | 69310 | France | Details | |
| Centre Hospitalier Universitaire (CHU) de Bordeaux - Hospitalier Saint-Andre | RECRUITING | Bordeaux | 33075 | France | Details | |
| Christie Hospital | ACTIVE_NOT_RECRUITING | Manchester | M20 4GJ | United Kingdom | Details | |
| CHRU de Lille - Hôpital Claude Huriez | RECRUITING | Lille | 59000 | France | Details | |
| CHU Dijon Bourgogne - Hopital Francois Mitterand (Hopital du Bocage) | RECRUITING | Dijon | 21079 | France | Details | |
| CLCC Institute Gustave Roussy | RECRUITING | Villejuif | 94805 | France | Details | |
| Cleveland Clinic Foundation | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| Fakultni nemocnice Hradec Kralove | RECRUITING | Nový Hradec Králové | 50005 | Czechia | Details | |
| Fred Hutchinson Cancer Center | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| Hollywood Private Hospital | RECRUITING | Nedlands | Western Australia | 6009 | Australia | Details |
| Hospital Ambroise Pairs | RECRUITING | Paris | 75010 | France | Details | |
| Hospital Clinic de Barcelona | RECRUITING | Barcelona | 08036 | Spain | Details | |
| Hospital General Universitario Gregorio Marañón | RECRUITING | Madrid | 28007 | Spain | Details | |
| Hospital HM Sanchinarro | RECRUITING | Madrid | 28050 | Spain | Details | |
| Hospital Universitari Vall d'Hebron - Vall d'Hebron Institut d'Oncologia (VHIO) | ACTIVE_NOT_RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Universitario Central de Asturias | ACTIVE_NOT_RECRUITING | Oviedo | 33011 | Spain | Details | |
| Hospital Universitario Ramon y Cajal | RECRUITING | Madrid | 28034 | Spain | Details | |
| IRCCS Istituto Nazionale Tumori Regina Elena | RECRUITING | Roma | 00144 | Italy | Details | |
| Isala Ziekenhuis | RECRUITING | Amsterdam | 8025 | Netherlands | Details | |
| Istituto Dermopatico dell Immacolata IDI-IRCCS | RECRUITING | Roma | 00167 | Italy | Details | |
| Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele (HSR) (Istituto Scientifico Universitario Sa | RECRUITING | Milan | 20132 | Italy | Details | |
| Leids Universitair Medisch Centrum | RECRUITING | Leiden | 2333 ZC | Netherlands | Details | |
| Masarykuv Onkologicky Ustav-MOU | RECRUITING | Brno | 65653 | Czechia | Details | |
| Massachusetts General Hospital | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Mayo Clinic | RECRUITING | Rochester | Minnesota | 70121 | United States | Details |
| Mayo Clinic - Arizona | RECRUITING | Phoenix | Arizona | 85054 | United States | Details |
| Mayo Clinic - Florida | RECRUITING | Jacksonville | Florida | 70121 | United States | Details |
| McGill University Health Centre | RECRUITING | Montréal | Quebec | H4A3J1 | Canada | Details |
| Memorial Sloan Kettering Cancer Center | RECRUITING | New York | New York | 10065 | United States | Details |
| Ochsner Clinic Foundation | ACTIVE_NOT_RECRUITING | Jefferson | Louisiana | 70121 | United States | Details |
| Peter MacCallum Cancer Institute | RECRUITING | Melbourne | Victoria | 3000 | Australia | Details |
| Princess Alexandra Hospital | RECRUITING | Woolloongabba | Queensland | 4102 | Australia | Details |
| Queen Elizabeth II Health Sciences Centre | RECRUITING | Halifax | Nova Scotia | B3J 3R4 | Canada | Details |
| Radboud University | RECRUITING | Nijmegen | 6525 GA | Netherlands | Details | |
| Royal Devon and Exeter Hospital | RECRUITING | Exeter | EX25DW | United Kingdom | Details | |
| Royal Preston Hospital | RECRUITING | Preston | Lancashire | PR29H | United Kingdom | Details |
| Sanatorium Profesora Arenbergera | RECRUITING | Prague | 1502 | Czechia | Details | |
| Sarah Cannon Research Institute - HCA Healthcare | RECRUITING | City of London | London | W1G 6AD | United Kingdom | Details |
| SCRI Oncology Partners (formerly Tennessee Oncology) | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Tasman Health Care | RECRUITING | Southport | Queensland | 4215 | Australia | Details |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | RECRUITING | Dallas | Texas | 75246 | United States | Details |
| Texas Oncology- Austin Midtown | RECRUITING | Austin | Texas | 78705 | United States | Details |
| The Melanoma and Skin Care Institute | RECRUITING | Englewood | Colorado | 80113 | United States | Details |
| The Royal Marsden NHS Foundation Trust | ACTIVE_NOT_RECRUITING | London | SM2 5PT | United Kingdom | Details | |
| The University of Texas MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| The University of Utah - Huntsman Cancer Institute (HCI) | RECRUITING | Salt Lake City | Utah | 84112 | United States | Details |
| University of California, San Francisco | RECRUITING | San Francisco | California | 94143 | United States | Details |
| University of Kansas Cancer Center | RECRUITING | Kansas City | Kansas | 66205 | United States | Details |
| University of Miami Sylvester Cancer | RECRUITING | Miami | Florida | 33136 | United States | Details |
| University of Wisconsin | RECRUITING | Madison | Wisconsin | 53792 | United States | Details |
| Virginia Oncology Associates | RECRUITING | Norfolk | Virginia | 23502-1871 | United States | Details |
| Washington University School of Medicine | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
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